Cleerly ISCHEMIA vs cmAngio®

Similar category, different focus. These tools serve overlapping but distinct needs. Comparability 65/100 Comparability is an AI-graded 0–100 score of how directly these two tools compete — higher means a more apples-to-apples comparison.
by Cleerly
VS
by CureMetrix

AI Verdict

While both Cleerly ISCHEMIA and cmAngio® utilize AI in medical imaging for cardiovascular insights, their primary applications and input modalities differ. Cleerly ISCHEMIA focuses on non-invasively determining the likelihood of coronary artery ischemia using CCTA scans for direct heart disease assessment. In contrast, cmAngio® detects Breast Arterial Calcifications on mammograms to aid in early cardiovascular risk assessment, rather than direct coronary disease diagnosis.

Choose Cleerly ISCHEMIA if…

Choose Cleerly ISCHEMIA if you require a comprehensive, non-invasive assessment of coronary artery disease and the likelihood of ischemia at a vessel level. This tool is ideal for physicians utilizing CCTA scans to precisely characterize coronary plaque, assess stenosis severity, and guide personalized treatment plans for patients with suspected or known heart disease.

View Cleerly ISCHEMIA →

Choose cmAngio® if…

Choose cmAngio® if you aim to leverage existing mammography data for early cardiovascular risk assessment in women. This AI software is best suited for identifying Breast Arterial Calcifications (BAC) on both FFDM and DBT exams, providing valuable insights into a patient's cardiovascular health without requiring additional radiation or procedures.

View cmAngio® →

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Quick Comparison

Feature Cleerly ISCHEMIA cmAngio®
Pricing Unknown Paid, out-of-pocket
Deployment Web-based solution Cloud-based, integrates with any DICOM-compliant viewer
BAA Available Yes AI-estimated Unknown
FDA Status Cleared AI-estimated Cleared AI-estimated
HIPAA Yes AI-estimated Yes AI-estimated

Head-to-Head

AI-generated assessment across six dimensions based on each tool's documented features and compliance posture. Grounded in public data — not a substitute for hands-on evaluation.

Usability

Cleerly ISCHEMIA

Cleerly ISCHEMIA offers comprehensive interactive web-based reports and explicitly mentions compliance with usability engineering standards, including formative and summative evaluations with cardiac specialists. While cmAngio boasts quick installation and compatibility with any DICOM viewer, Cleerly's focus on interactive reporting and validated usability suggests a potentially richer user experience.

Clinical Value

Cleerly ISCHEMIA

Cleerly ISCHEMIA provides direct diagnostic and prognostic value for coronary artery disease by non-invasively determining the likelihood of ischemia at a vessel level, estimating FFR, and characterizing plaque, validated in multiple trials against invasive FFR. cmAngio offers valuable cardiovascular risk assessment by detecting breast arterial calcifications on mammograms, but Cleerly's immediate diagnostic and prognostic impact on active heart disease management is more direct and comprehensive.

Pricing & Value

Cleerly ISCHEMIA

Cleerly ISCHEMIA has a significant advantage with established Category I CPT codes (75580 for FFR estimation and 75577 for plaque analysis in 2026), providing clear reimbursement pathways and reducing financial uncertainty for providers. While both tools require contacting for specific pricing, Cleerly's transparent reimbursement structure offers a stronger value proposition for healthcare systems.

Enterprise Readiness

Cleerly ISCHEMIA

Cleerly ISCHEMIA explicitly states it has a Business Associate Agreement (BAA) and is HIPAA compliant, which is a critical component for enterprise-level data handling and compliance in healthcare. Although cmAngio is also HIPAA compliant and has expanded compatibility with imaging platforms, its requirement to contact the vendor for BAA details introduces a minor hurdle compared to Cleerly's upfront declaration of BAA availability.

Innovation

Cleerly ISCHEMIA

Cleerly ISCHEMIA demonstrates higher innovation by non-invasively estimating fractional flow reserve (FFR) and providing a comprehensive 3-in-1 assessment of atherosclerosis, stenosis, and ischemia from a single CCTA, which previously required more invasive or separate functional tests. While cmAngio innovatively repurposes existing mammography data for cardiovascular risk assessment, Cleerly's advancement in functional cardiac assessment from non-invasive imaging represents a more profound technological leap in its field.

Support & Docs

Cleerly ISCHEMIA

Cleerly ISCHEMIA provides a more extensive and clearly categorized array of support and documentation resources, including patient education, FAQs, billing guidelines, imaging protocols, and various publications. While cmAngio mentions an Operator's Manual and publications, Cleerly's broader range of accessible materials for different stakeholders suggests a more comprehensive support ecosystem.

Feature-by-Feature

Detail beyond the Quick Comparison summary. For pricing, deployment, BAA, FDA, and HIPAA see the Overview tab.

Feature Cleerly ISCHEMIA cmAngio®
Name Cleerly ISCHEMIA cmAngiou00ae
Primary Use Case / Target Condition Non-invasively determine the likelihood of coronary artery ischemia at a vessel level, aiding physicians in personalized diagnosis and treatment planning for heart disease. Detecting Breast Arterial Calcifications (BAC) on mammograms, providing insights into cardiovascular health and aiding early risk assessment.
Key Analysis Method AI-enabled CCTA analysis; Non-invasive fractional flow reserve (FFR) estimation; Coronary plaque characterization; Stenosis severity assessment. AI-based detection of Breast Arterial Calcifications (BAC).
Input Data Type CCTA scans Full-Field Digital Mammography (FFDM) and Digital Breast Tomosynthesis (DBT) exams
Specialties Cardiology, Radiology Cardiology, Obstetrics & Gynecology, Radiology

Videos

Demos, reviews, and walkthroughs featuring Cleerly ISCHEMIA and cmAngio®.

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Frequently Asked Questions

Cleerly ISCHEMIA analyzes CCTA scans to non-invasively determine the likelihood of coronary artery ischemia at a vessel level, aiding in personalized diagnosis and treatment planning for heart disease. cmAngio detects Breast Arterial Calcifications (BAC) on mammograms, providing insights into cardiovascular health and aiding early risk assessment, primarily for women.
Cleerly ISCHEMIA analyzes Coronary Computed Tomography Angiography (CCTA) scans. cmAngio processes both Full-Field Digital Mammography (FFDM) and Digital Breast Tomosynthesis (DBT) exams.
Cleerly ISCHEMIA provides non-invasive fractional flow reserve (FFR) estimation, coronary plaque characterization (volume, type, location), stenosis severity assessment, and comprehensive interactive web-based reports with 3D digital models of coronary arteries. cmAngio provides visualization of BAC location on a scorecard and enables BAC identification and reporting.
Cleerly ISCHEMIA is a web-based platform with data transfer via Cleerly Proxy (VPN or virtual appliance) and integrates with PowerScribe via API. cmAngio is compatible with any DICOM-compliant viewer and offers quick and easy installation, typically in less than an hour.

Backers

Who funded each tool's parent company.

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