Cleerly ISCHEMIA vs ElucidVivo A.3

Similar category, different focus. These tools serve overlapping but distinct needs. Comparability 70/100 Comparability is an AI-graded 0–100 score of how directly these two tools compete — higher means a more apples-to-apples comparison.
by Cleerly
VS
by Elucid

AI Verdict

Cleerly ISCHEMIA focuses on assessing the likelihood of coronary artery ischemia and characterizing coronary plaque from CCTA scans to guide heart disease diagnosis and treatment. ElucidVivo A.3, while also analyzing arterial plaque from CT angiography, specializes in quantitative analysis of plaque composition and stability, including specific components like LRNC, to stratify atherosclerosis patients. Therefore, Cleerly is more geared towards functional assessment of ischemia, while ElucidVivo provides deeper insights into the structural and compositional risks associated with plaque.

Choose Cleerly ISCHEMIA if…

Choose Cleerly ISCHEMIA if your primary goal is to non-invasively determine the likelihood of coronary artery ischemia at a vessel level and obtain a comprehensive characterization of coronary plaque from CCTA scans. This tool is ideal for physicians seeking to personalize diagnosis and treatment planning for patients with suspected heart disease by understanding both functional impairment and overall plaque burden.

View Cleerly ISCHEMIA →

Choose ElucidVivo A.3 if…

Choose ElucidVivo A.3 if you require detailed, quantitative analysis of arterial plaque composition and stability, including specific quantification of Lipid-Rich Necrotic Core (LRNC), from CT angiography. This system is particularly well-suited for stratifying atherosclerosis patients and optimizing treatment decisions based on precise, histology-validated insights into plaque vulnerability and characteristics.

View ElucidVivo A.3 →

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Quick Comparison

Feature Cleerly ISCHEMIA ElucidVivo A.3
Deployment Web-based solution Cloud and on-premise secure deployment.
BAA Available Yes AI-estimated Unknown
FDA Status Cleared AI-estimated Cleared AI-estimated
HIPAA Yes AI-estimated Yes AI-estimated

Head-to-Head

AI-generated assessment across six dimensions based on each tool's documented features and compliance posture. Grounded in public data — not a substitute for hands-on evaluation.

Usability

Cleerly ISCHEMIA

Cleerly ISCHEMIA operates on a web-based platform with comprehensive interactive web-based reports, suggesting a modern and accessible user experience. Furthermore, its compliance with usability engineering standards and documented evaluations indicate a focus on user-friendly design.

Clinical Value

Cleerly ISCHEMIA

Cleerly ISCHEMIA directly determines the likelihood of coronary artery ischemia at a vessel level and provides non-invasive FFR estimation, validated against invasive FFR. It has also demonstrated prognostic utility for future Major Adverse Cardiac Events (MACE), offering a more immediately actionable clinical impact for guiding treatment decisions.

Pricing & Value

Tie

Both tools require direct contact for pricing, making a comparative assessment of cost impossible. However, both Cleerly ISCHEMIA and ElucidVivo A.3 have secured Category I CPTu00ae codes for their respective analyses, which significantly enhances their value proposition to providers through improved reimbursement potential.

Enterprise Readiness

Cleerly ISCHEMIA

Cleerly ISCHEMIA explicitly states its HIPAA compliance and the availability of a Business Associate Agreement (BAA). Its deployment as a web-based platform with a clear data transfer mechanism via Cleerly Proxy and integration with PowerScribe via API demonstrates a well-defined and transparent enterprise strategy.

Innovation

ElucidVivo A.3

While both leverage AI for advanced CCTA analysis, ElucidVivo A.3's innovation stands out in its objective quantification of specific arterial plaque components, such as Lipid-Rich Necrotic Core (LRNC), matrix, and calcifications, which is uniquely validated against ground-truth histology. This provides a deeper and more precise understanding of plaque stability and vulnerability.

Support & Docs

Cleerly ISCHEMIA

Cleerly ISCHEMIA provides explicit client support channels, including a dedicated form for technical support for existing users and specified operating hours (Monday-Friday, 10 am ET to 6 pm ET). This level of transparency and readily available support resources is not as evident for ElucidVivo A.3 based on the available information.

Feature-by-Feature

Detail beyond the Quick Comparison summary. For pricing, deployment, BAA, FDA, and HIPAA see the Overview tab.

Feature Cleerly ISCHEMIA ElucidVivo A.3
Primary Purpose Analyzes CCTA scans to non-invasively determine the likelihood of coronary artery ischemia at a vessel level, aiding physicians in personalized diagnosis and treatment planning for heart disease. Provides quantitative analysis of arterial plaque composition and stability from CT angiography, assisting physicians in atherosclerosis patient stratification and optimizing treatment decisions.
Target Specialties Cardiology, Radiology Cardiology, Radiology, Vascular Surgery
Core Analysis Focus AI-enabled CCTA analysis, vessel-level ischemia likelihood determination, coronary plaque characterization, stenosis severity assessment. AI-powered quantitative analysis of arterial plaque, objectively quantifies Lipid-Rich Necrotic Core (LRNC), matrix, and calcifications from CT images, aids in stratifying patients with atherosclerosis.
FFR Estimation Non-invasive fractional flow reserve (FFR) estimation Derives fractional flow reserve (FFRct) based on vessel wall vasodilative capacity
Plaque Characterization Coronary plaque characterization (volume, type, location) Objectively quantifies Lipid-Rich Necrotic Core (LRNC), matrix, and calcifications from CT images; visualizes lesion-level plaque composition; validated on ground-truth histology.
3D Visualization 3D digital models of coronary arteries Provides 3D visualization of highlighted vessels; offers rotatable curved MPR vessel views and cross-sections.

Videos

Demos, reviews, and walkthroughs featuring Cleerly ISCHEMIA and ElucidVivo A.3.

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Frequently Asked Questions

Cleerly ISCHEMIA is designed to non-invasively determine the likelihood of coronary artery ischemia at a vessel level and assess stenosis severity using CCTA scans. ElucidVivo A.3 focuses on providing quantitative analysis of arterial plaque composition and stability from CT angiography to aid in atherosclerosis patient stratification.
Cleerly ISCHEMIA offers coronary plaque characterization, including volume, type, and location, along with stenosis severity assessment. ElucidVivo A.3 objectively quantifies specific plaque components such as Lipid-Rich Necrotic Core (LRNC), matrix, and calcifications from CT images, and visualizes lesion-level plaque composition.
Cleerly ISCHEMIA provides non-invasive fractional flow reserve (FFR) estimation as part of its vessel-level ischemia likelihood determination, with its algorithm using measurements based on invasive FFR data. ElucidVivo A.3 derives fractional flow reserve (FFRct) based on vessel wall vasodilative capacity.
Cleerly ISCHEMIA is a web-based platform with data transfer facilitated by Cleerly Proxy (VPN or virtual appliance) and offers integration with PowerScribe via API. ElucidVivo A.3 is a software application, likely on-premise or cloud-based, that integrates with PACS/EMR systems.
ElucidVivo A.3 explicitly states that its detailed visualization and measurement of plaque characteristics are validated against ground-truth histology. Cleerly ISCHEMIA's description mentions its analyses are grounded in science and based on extensive image data from clinical trials, and its ischemia determination was validated against invasive FFR as the gold standard, but does not explicitly detail histology validation for plaque composition.

Backers

Who funded each tool's parent company.

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