DeepXray

by Alpha Intelligence Manifolds  · Based in Taiwan → — Affordable Smart Precision Care Serving Aging Society
Orthopedics Radiology Rheumatology

Subscription-based
Regulatory Status Disclosed

Overview

DeepXray is an AI-powered software developed by Alpha Intelligence Manifolds that assists medical professionals in analyzing X-rays to detect signs of osteoarthritis and measure joint space width, as well as for precision diagnosis and automated monitoring of osteoporosis. It is a fully automated image processing software designed to aid in evaluating knee, lumbar spine, and pelvic X-rays. The software measures minimum joint space width and assesses signs of osteoarthritis, including sclerosis, joint space narrowing, and osteophytes, based on established radiographic criteria. For osteoporosis, it estimates Bone Mineral Density (BMD) of the Total Hip and Lumbar Spine L1-L4 and provides fracture risk categories. DeepXray provides detailed grading and offers an interactive report for clinician review and editing before finalization. It is intended for use by trained professionals such as radiologists, orthopedists, physicians, and medical technicians.

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Key Features

  • AI-assisted diagnosis system for knee X-rays (osteoarthritis)
  • Automated measurement of joint space width
  • Assessment of osteoarthritis signs (sclerosis, joint space narrowing, osteophytes)
  • Grading based on OARSI criteria
  • Interactive report generation for clinician review and editing
  • AI-assisted diagnosis system for osteoporosis using X-rays (DeepXray Coxa/Spina)
  • Automated progression monitoring for chronic bone diseases
  • Bone Mineral Density (BMD) estimation (DeepXray Coxa/Spina)
  • Fracture risk categories based on WHO Criteria (DeepXray Coxa/Spina)
  • Integration with DeepPACS AI-assisted PACS platform

Use Cases

  • Early detection and diagnosis of osteoarthritis
  • Automated monitoring of osteoarthritis progression
  • Precision diagnosis and monitoring of osteoporosis
  • Assisting radiologists, orthopedists, and physicians in X-ray interpretation
  • Streamlining workflow in medical imaging via AI-driven reporting
  • Enhancing patient awareness and return visit rates for chronic bone diseases

What Physicians Need to Know

Evidence Base
DeepXray's assessment of osteoarthritis (OA) is based on established radiographic criteria, including the Kellgren-Lawrence Grade (KL Grade) and OARSI (Osteoarthritis Research Society International) grading criteria. For osteoporosis, it utilizes T-score, Z-score, BMD conversion based on ISCD and NHANES, and fracture risk categories aligned with WHO Criteria.
Clinical Validation Studies
DeepXray Genu's clinical performance for knee OA was validated on an independent test dataset from the Osteoarthritis Initiative (OAI), comprising 6,125 knee radiographs from 1,121 individuals, demonstrating good agreement with clinical professionals' labeling. DeepXray Coxa/Spina for osteoporosis shows excellent agreement with DXA, with a Pearson's correlation coefficient > 0.9, accuracy RMSE 90%. The tool has received FDA 510(k) clearance and T-FDA approval.
Clinical Workflow Integration
DeepXray is a fully automated image processing software designed to generate interactive reports for clinician review and editing. It supports a 'Zero-Click' instant AI report generation through its DeepPACS integration, leveraging standard DICOM services for a streamlined workflow. Clinicians can verify AI reports side-by-side with original radiographs and modify automated analysis results based on their professional judgment.
Decision Audit Trail
The system allows clinical professionals to modify AI analysis results based on their professional judgment before saving and outputting the report, implying a record of the AI's initial output and any subsequent human intervention. DeepXray is compliant with HIPAA, GDPR, and ISO 27001, indicating adherence to data security and accountability standards.
Physician Tip

1. **Review and Validate:** Always leverage the interactive reports to review AI analysis alongside original X-rays. Use your clinical judgment to confirm or modify findings before finalization, as DeepXray is an assistive tool and not a replacement for full patient evaluation.n2. **Standardize Assessment:** Utilize the automated measurements and grading (e.g., KL/OARSI for OA, T/Z-scores for osteoporosis) to standardize assessments, track disease progression, and enhance consistency in reporting over time.n3. **Streamline Workflow:** Integrate DeepXray with your existing PACS/RIS systems to benefit from streamlined workflows and 'Zero-Click' instant AI report generation, optimizing efficiency in your practice.

DeepXray is designed for seamless integration within existing medical imaging infrastructure, particularly through its DeepPACS platform. It supports standard DICOM services, enabling efficient image transfer and 'Zero-Click' AI report generation. The system offers flexible deployment models (SaaS, on-premise, or hybrid) and is compatible with key healthcare data standards including DICOM, HL7 v2, FHIR, SNOMED CT, and ICD-10.

Details

Category Clinical Decision Support & Reference, Radiology & Imaging AI
Pricing Subscription-based — Subscription-based; contact vendor directly for detailed pricing information.
DeploymentSaaS, on-premise, hybrid
Compliance
BAA AvailableUnknown AI-estimated
HIPAA CompliantUnknown AI-estimated
FDA Status 1 AI-estimated

DeepXray has received FDA 510(k) clearance (K223621) as a standalone software device that utilizes artificial intelligence and computer vision algorithms to assist clinical professionals in analyzing and measuring radiographic abnormalities of knee osteoarthritis during review of X-rays.

Integrations
EHR Not specified
Specialties Orthopedics, Radiology, Rheumatology

What the Web Says

DeepXray, developed by Alpha Intelligence Manifolds, is an AI-powered software designed to assist medical professionals in analyzing knee X-rays for signs of osteoarthritis and measuring joint space width. It provides automated image processing, detailed grading based on OARSI criteria, and interactive reports for clinician review. The software is FDA-cleared and intended for use by trained professionals such as radiologists, orthopedists, physicians, and medical technicians.

Overall: Positive

Strengths

  • AI-assisted diagnosis for knee X-rays.
  • Automated measurement of joint space width.
  • Assessment of osteoarthritis signs (sclerosis, joint space narrowing, osteophytes).
  • Grading based on OARSI criteria.
  • Interactive report generation for clinician review and editing.
  • FDA clearance for use in the United States.

Limitations

  • No specific cons found for DeepXray in the provided search results.
  • General concerns about AI research tools include accuracy issues, lack of context, and limitations with data access.

Based on reviews from: HealthAidb, Capterra, Reddit, G2

Last updated: 2026-07-17

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Press & Coverage

Alpha Intelligence Manifolds, Inc. (AIMfolds)
DeepXrayu2122 u52c7u596au65e5u672cITEM2025u91abu7642u5f71u50cfu5c55u7b2c2u540d (DeepXrayu2122 Wins 2nd Place at Japan ITEM2025 Medical Imaging Exhibition)
AIM's independently developed AI medical imaging assisted diagnosis system, DeepXrayu2122, won second place at the International Medical Imaging Technology and Equipment Exhibition (ITEM2025) held in Yokohama, Japan in April.
2025-07
Alpha Intelligence Manifolds, Inc. (AIMfolds)
u91c7u98a8u667au532fu65bcIOF Regional 2025uff0cTokyo u767cu8868u591au9805AI u9aa8u5bc6u5ea6u8de8u570bu7814u7a76u6210u679c (AIMfolds Presents Multiple AI Bone Density International Research Results at IOF Regional 2025, Tokyo)
AIMfolds, in collaboration with osteoporosis experts from Taiwan and Japan, presented several AI bone density international research results at IOF Regional 2025 in Tokyo, focusing on the clinical evidence of osteoporosis detection and fracture risk prediction.
2025-12
Alpha Intelligence Manifolds, Inc. (AIMfolds)
u4e9eu6771u91abu9662u5c0eu5165DeepXrayu2122 u9aa8u9b06AIu8f14u52a9u8a3au65b7u7cfbu7d71 (Far Eastern Memorial Hospital Introduces DeepXrayu2122 Osteoporosis AI-Assisted Diagnosis System)
Far Eastern Memorial Hospital has adopted the DeepXrayu2122 osteoporosis AI-assisted diagnosis system, which can detect bone mineral density from a single X-ray, aiming to build a proactive osteoporosis prevention network in Taiwan.
2025-10
Alpha Intelligence Manifolds, Inc. (AIMfolds)
u91c7u98a8u667au532fu65b0u7522u54c1uff1aDeepXrayu2122 Spinau9aa8u8ceau758fu9b06u75c7AIu8f14u52a9u8a3au65b7u8edfu9ad4u518du7372TFDAu8a31u53ef (AIMfolds New Product: DeepXrayu2122 Spina Osteoporosis AI-Assisted Diagnosis Software Receives Another TFDA Approval)
Alpha Intelligence Manifolds, Inc. (AIM) announced that its new product, DeepXrayu2122 Spina, an AI-assisted diagnostic software for osteoporosis, has once again received TFDA approval.
2024-11
Alpha Intelligence Manifolds, Inc. (AIMfolds)
u667au6167u5316u9aa8u79d1u6162u6027u75c5u6aa2u6e2cu555fu52d5u8a18u8005u6703-u6843u885bu5c40u8207u91c7u98a8u667au532fu5408u4f5cu63a8u52d5u9aa8u8ceau5bc6u5ea6u53cau9000u5316u6027u95dcu7bc0u708eAIu5224u8b80u6aa2u6e2c (Smart Orthopedic Chronic Disease Detection Launch Press Conference - Taoyuan Department of Health Collaborates with AIMfolds to Promote AI Interpretation of Bone Mineral Density and Osteoarthritis)
The Taoyuan Department of Health is collaborating with Alpha Intelligence Manifolds (AIMfolds) to promote AI-powered bone mineral density and osteoarthritis interpretation, marking the launch of smart orthopedic chronic disease detection.
2024-06
Alpha Intelligence Manifolds, Inc. (AIMfolds)
DeepXrayu2122 Coxa and DeepXrayu2122 Spina enables faster and more extensive clinical capabilities of diagnosing osteoporosis using conventional X-ray equipment.
DeepXrayu2122 Coxa and DeepXrayu2122 Spina offer enhanced clinical capabilities for osteoporosis diagnosis using standard X-ray equipment, providing precision diagnosis, multi-part BMD estimation, and fracture risk categorization.
2024-10
accessdata.fda.gov
DeepXray is substantially equivalent to its predicate devices.
The FDA determined that DeepXray is substantially equivalent to its predicate devices, affirming its intended use, similar indications, technological characteristics, and principles of operation for aiding medical professionals in osteoarthritis assessment.
2023-08
Annals of African Medicine
Predicting Osteoporosis Risk from Knee Radiographs and Clinical Features through Deep Learning: A Multimodal Approach
This study demonstrates a promising multimodal deep learning approach combining radiographic features from knee X-rays with clinical parameters for osteoporosis screening, offering a cost-effective alternative in settings with limited DEXA scan access.
2026-04

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Suggest an Edit → | Last Verified: 2026-04-17 | First Added: 2026-04-17
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