HeartFlow Analysis vs Tempus ECG-Low EF

Similar category, different focus. These tools serve overlapping but distinct needs. Comparability 65/100 Comparability is an AI-graded 0–100 score of how directly these two tools compete — higher means a more apples-to-apples comparison.
by Heartflow
VS
by Tempus

AI Verdict

HeartFlow Analysis is designed for non-invasive diagnosis and management of coronary artery disease, leveraging CT scans to create 3D models and assess coronary blood flow and plaque characteristics. In contrast, Tempus ECG-Low EF utilizes AI to analyze ECG recordings to detect signs associated with low left ventricular ejection fraction, aiding in the identification of patients at risk for heart failure. While both are cardiology AI tools, they serve distinct diagnostic purposes, utilize different input data (CT vs. ECG), and provide different types of clinical insights.

Choose HeartFlow Analysis if…

Choose HeartFlow Analysis if you require a comprehensive, non-invasive assessment of coronary artery disease, including both anatomical stenosis and its functional impact. This tool is ideal for patients with suspected or known CAD who need detailed insights into blood flow and plaque characteristics derived from standard CT scans, helping to guide treatment decisions and potentially avoid invasive procedures.

View HeartFlow Analysis →

Choose Tempus ECG-Low EF if…

Choose Tempus ECG-Low EF if you need an efficient, AI-powered screening tool to identify patients aged 40 or older at risk of heart failure by detecting signs of low left ventricular ejection fraction from a standard 12-lead ECG. This solution is best suited for rapid risk stratification in clinical settings to prompt further diagnostic evaluation, such as an echocardiogram, for those identified as having potential low LVEF.

View Tempus ECG-Low EF →

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Quick Comparison

Feature HeartFlow Analysis Tempus ECG-Low EF
Pricing Contact vendor for pricing Unknown
Deployment Cloud-based (AWS) Integrates with current ECG platforms and electronic health records (EHRs).
BAA Available Yes AI-estimated Unknown
FDA Status Cleared AI-estimated Cleared AI-estimated

Head-to-Head

AI-generated assessment across six dimensions based on each tool's documented features and compliance posture. Grounded in public data — not a substitute for hands-on evaluation.

Usability

Tempus ECG-Low EF

Tempus ECG-Low EF provides a straightforward binary output (Low LVEF Detected / Not Detected) from standard ECG recordings, making it highly usable for quick interpretation and integration into fast-paced clinical workflows. HeartFlow Analysis, while valuable, generates detailed 3D models and FFRct values, which may require more specialized review and interpretation time.

Clinical Value

HeartFlow Analysis

HeartFlow Analysis offers a comprehensive, non-invasive diagnostic assessment for coronary artery disease (CAD) by providing FFRct analysis, plaque quantification, and 3D models, directly guiding treatment decisions. Tempus ECG-Low EF serves as a valuable screening tool for low LVEF, aiding in identifying patients at risk of heart failure, but it prompts further evaluation rather than providing a definitive diagnosis for a specific disease.

Pricing & Value

HeartFlow Analysis

HeartFlow Analysis has established Category I CPT codes for FFRct Analysis and AI-Enabled Quantitative Plaque Analysis, with CMS payment rates already in place. This clear reimbursement pathway significantly de-risks adoption for healthcare providers. Tempus ECG-Low EF's pricing and reimbursement details are not specified in the provided information, making its financial value proposition less transparent.

Enterprise Readiness

Tie

Both tools demonstrate strong foundational enterprise readiness with FDA clearance, HIPAA compliance, and Business Associate Agreements (BAAs). HeartFlow explicitly mentions cloud-based deployment on AWS, suggesting scalability, while Tempus states integration into healthcare facility workflows. Without more specific details on their respective integration capabilities and enterprise features, it is difficult to definitively distinguish between them.

Innovation

HeartFlow Analysis

HeartFlow Analysis represents a significant innovation by integrating AI with advanced computational fluid dynamics (CFD) to derive functional fractional flow reserve (FFRct) from standard CT scans, offering a non-invasive alternative to invasive FFR. While Tempus ECG-Low EF's application of AI to ECGs for LVEF detection is also innovative, HeartFlow's approach involved a more complex scientific and engineering breakthrough to transform anatomical data into functional insights.

Support & Docs

Tie

The provided structured facts do not contain any specific information regarding the availability, quality, or scope of support and documentation for either HeartFlow Analysis or Tempus ECG-Low EF. Therefore, it is not possible to make a comparative judgment on this dimension.

Feature-by-Feature

Detail beyond the Quick Comparison summary. For pricing, deployment, BAA, FDA, and HIPAA see the Overview tab.

Feature HeartFlow Analysis Tempus ECG-Low EF
Tool Name HeartFlow Analysis Tempus ECG-Low EF
Company HeartFlow Tempus AI
Primary Function Non-invasive diagnosis and management of coronary artery disease (CAD) via 3D models from CT scans Detects signs associated with low left ventricular ejection fraction (LVEF u226440%) from 12-lead ECG recordings
Data Input Standard CT scans 12-lead ECG recordings
Key Output AI-powered 3D modeling of coronary arteries, FFRct analysis, Plaque Analysis, Roadmapu2122 Analysis Binary output (Low LVEF Detected / Not Detected)
Target Condition Coronary Artery Disease (CAD) Low Left Ventricular Ejection Fraction (LVEF u226440%)

Videos

Demos, reviews, and walkthroughs featuring HeartFlow Analysis and Tempus ECG-Low EF.

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Frequently Asked Questions

HeartFlow Analysis is designed for diagnosing and managing coronary artery disease (CAD) by providing detailed insights into coronary artery anatomy, plaque characteristics, and blood flow. Tempus ECG-Low EF is intended to analyze 12-lead ECG recordings to detect signs associated with low left ventricular ejection fraction (LVEF u226440%) in patients 40 years or older at risk of heart failure.
HeartFlow Analysis utilizes data from standard CT scans of the coronary arteries to create its personalized 3D models and analyses. Tempus ECG-Low EF requires resting, non-ambulatory 12-lead ECG recordings for its AI-powered analysis.
HeartFlow Analysis provides personalized 3D models of coronary arteries, fractional flow reserve derived from CT (FFRct) analysis, and plaque quantification and characterization. In contrast, Tempus ECG-Low EF delivers a binary output indicating whether low LVEF is detected or not detected.
HeartFlow Analysis has established Category I CPT codes for FFRct Analysis (75580) and AI-Enabled Quantitative Plaque Analysis (75577 for 2026), with coverage by Medicare and most U.S. commercial payers and established CMS payment rates. For Tempus ECG-Low EF, pricing requires contacting the vendor, and while Tempus's ECG-AF algorithm has received CMS reimbursement, specific Category I CPT codes for ECG-Low EF are not detailed in the provided information.
HeartFlow Analysis is primarily used by cardiologists and radiologists for the diagnosis and management of CAD. Tempus ECG-Low EF is intended for use by cardiologists, emergency medicine physicians, and internal medicine physicians to aid in identifying patients at risk of heart failure due to low LVEF.

Backers

Who funded each tool's parent company.

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