Boulder Ventures

VC Boulder, United States · Founded 1995

About Boulder Ventures

Boulder Ventures is a venture capital firm based in Boulder that supports life sciences and healthcare technology startups emerging from the Colorado ecosystem. Healthcare exposure spans life sciences tools and health IT software, which gives the firm an unusual combination of bench-science adjacency and software fluency. AI is not the headline; what the firm brings is regional specialization and ties to Front Range universities, research institutions, and the broader Mountain West technology cluster.

The fund invests at Series A and Series B with check sizes of $1M to $5M. That sizing makes Boulder Ventures a candidate to participate meaningfully in early-mid stage rounds, often co-investing alongside larger national funds rather than leading by itself. The Boulder location reflects a real geographic preference: founders with a Colorado footprint or Mountain West ties will get faster traction.

Founders should approach Boulder Ventures when they are building a life sciences tools company — instrumentation, software for research workflows, lab automation — or a health IT platform with regional roots. Therapeutics, devices, services-heavy care delivery, and pure consumer health are unlikely to be a good fit. Because the firm spans two distinct sub-verticals, partner alignment matters; founders should target the pitch accordingly. Expect questions about how the company scales beyond the local ecosystem and what national co-investors will look like in subsequent rounds. Bring clarity on milestones and capital plan.

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Team

Kyle Lefkoff
Founder & General Partner
LinkedIn

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Last updated 2026-05-06. Sourced from this fund's published materials.
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