Renalytix AI

London, United Kingdom (registered office) / New York, United States (main country of operation)  All United Kingdom companies → — Founded 2018
Point-of-Care Diagnostics Specialty-Focused AI
Endocrinology Internal Medicine Nephrology
Endocrinology & Metabolic AI Lab & Diagnostics
Post-IPO Equity

Products

KidneyIntelX.dkd
Renalytix AI
Endocrinology & Metabolic AI
KidneyIntelX.dkd by Renalytix AI is an FDA-authorized AI-enabled diagnostic test that predicts the risk of progressive kidney function decline in adults with Type 2 diabetes and early-stage chronic kidney disease, enabling earlier intervention.

See all 1 product →

About Renalytix AI

Renalytix AI is an artificial intelligence-enabled in vitro diagnostics company focused on improving the clinical management of kidney disease to enhance patient outcomes and reduce healthcare costs. The company’s primary product, KidneyIntelX, is a diagnostic platform that utilizes a proprietary AI-enabled algorithm. This algorithm integrates diverse data inputs, including validated blood-based biomarkers, inherited genetics, and personalized patient data from electronic health record (EHR) systems, to generate a unique patient risk score. This score helps predict progressive kidney function decline in individuals with chronic kidney disease (CKD), allowing physicians and healthcare systems to optimize treatment and allocate clinical resources more effectively to high-risk patients.

KidneyIntelX is particularly focused on diabetic kidney disease (DKD), which accounts for nearly 40% of CKD cases. The test has received FDA approval and Medicare reimbursement, and the company is actively expanding its reach through partnerships with healthcare providers and insurers. Renalytix AI aims to transform kidney disease risk assessment and clinical management by providing early detection and intervention capabilities, ultimately striving to lower healthcare costs and improve the quality of life for patients.

Focus Areas

AI-enabled in vitro diagnostics kidney disease diabetic kidney disease (DKD) risk assessment patient outcomes precision medicine chronic kidney disease management

Business Intelligence

TechnologyKidneyIntelX, an AI-enabled in vitro diagnostics platform that utilizes a proprietary machine learning algorithm (random forest) to combine blood-based biomarkers (sTNFR1, sTNFR2, KIM1), inherited genetics, and electronic health record (EHR) data to generate a patient risk score for progressive kidney function decline.

What Physicians Need to Know

Specialization
Renalytix AI specializes in AI-enabled in vitro diagnostics for kidney disease, particularly diabetic kidney disease (DKD). Their primary focus is on risk assessment, improving patient outcomes, and advancing precision medicine and chronic kidney disease management.
Key Product
Their flagship product is KidneyIntelX.dkd, an FDA-approved and Medicare-reimbursed prognostic test.
Risk Assessment
KidneyIntelX.dkd uses a machine learning algorithm to assess a patient's risk (low, moderate, or high) for progressive decline in kidney function over five years. This assessment combines blood-based biomarkers (sTNFR1, sTNFR2, and KIM1), inherited genetics, and data from electronic health records (EHR).
Improved Outcomes
The test aims to enable earlier, risk-guided interventions, reduce costly dialysis starts, and improve long-term kidney and cardiovascular health. Studies have shown that KidneyIntelX.dkd can lead to a 72% relative improvement in identifying high-risk patients compared to traditional methods.
Precision Medicine
Renalytix AI's approach allows clinicians to tailor monitoring and treatment strategies, leading to more precise and effective interventions. High-risk patients are more likely to be prescribed life-preserving medications and referred to nephrologists earlier.
Physician Tip

For physicians, Renalytix AI's KidneyIntelX.dkd offers a powerful tool to identify patients with type 2 diabetes and early-stage chronic kidney disease who are at high risk of rapid kidney function decline. This allows for earlier, guideline-recommended treatment and intervention, potentially slowing disease progression and improving patient outcomes. The test provides an easy-to-understand risk score with specific clinical recommendations, helping to optimize patient treatment and compliance. The integration of blood biomarkers and EHR data provides a comprehensive risk assessment that goes beyond traditional kidney function markers. This precision medicine approach can help physicians make informed decisions about patient management, including medication adjustments (e.g., SGLT2 inhibitors), lifestyle interventions, and timely referrals to specialists.

Renalytix AI's KidneyIntelX.dkd integrates data from blood-based biomarkers and electronic health records (EHR) using AI-enabled algorithms. They have established partnerships with healthcare systems and digital health companies like Carna Health and Tempus AI to expand access and integrate their testing into existing clinical workflows. This allows for electronic reporting of patient results to ordering clinicians and patient portals. Collaborations with academic medical centers like Mount Sinai, Emory University, and the University of Pennsylvania have been crucial for clinical validation and data generation.

Products by Renalytix AI

1 product in the directory

KidneyIntelX.dkd
Renalytix AI
Endocrinology & Metabolic AI
KidneyIntelX.dkd by Renalytix AI is an FDA-authorized AI-enabled diagnostic test that predicts the risk of progressive kidney function decline in adults with Type 2 diabetes and early-stage chronic kidney disease, enabling earlier intervention.

What the Web Says

Renalytix AI is a healthcare technology company that utilizes artificial intelligence to improve kidney disease diagnosis and management, primarily through its KidneyIntelX platform. The company's main product, KidneyIntelX.dkd, is an FDA-authorized prognostic test that identifies patients at risk for progressive decline in kidney function, especially those with Type 2 diabetes and early-stage chronic kidney disease. While there's enthusiasm for its innovative technology and potential to improve patient outcomes and reduce healthcare costs, some employer reviews suggest challenges with senior management and a potentially unhealthy work environment.

Overall: Mixed

Strengths

  • Innovative AI-powered diagnostic platform for kidney disease.
  • FDA authorization for KidneyIntelX.dkd.
  • Potential to improve patient outcomes and lower healthcare costs.
  • Strong partnerships, including with Mount Sinai Health System.
  • Employees are excited about contributing to game-changing technology.
  • Remote work philosophy and comprehensive benefits for US employees.

Limitations

  • Some employer reviews mention an unhealthy work environment.
  • Concerns about absentee leadership and incompatible senior management.
  • Lengthy FDA review process for KidneyIntelX.
  • Limited information available on G2, Glassdoor, and Capterra specifically for Renalytix AI product reviews.
  • Reddit discussions primarily focus on stock performance and investment potential rather than product or employer experience.

Based on reviews from: G2.com, LWW.com, Ovid.com, FierceBiotech.com, Investing.com, Renalytix.com, MedTechDive.com, Reddit.com, Indeed.com, AnnualReports.com, Capterra.com, Trustpilot.com

Last updated: 2026-10-29

Videos

News, demos, and interviews about Renalytix AI.

Loading videos...

Videos load interactively. If none appear, search YouTube for Renalytix AI →

View all on YouTube

Press & Coverage

kalkinemedia.com
UBS Group AG Reduces Stake in Renalytix PLC (RENX) Below 5% Voting Rights Threshold
UBS Group AG's Investment Bank and Global Wealth Management division reduced its stake in Renalytix PLC to below the 5% major shareholding threshold on October 27, 2026, with trading book holdings declining to zero reportable voting rights. This regulatory disclosure indicates a significant change in the institutional shareholder base of the AI-driven kidney disease diagnostics firm.
2026-10
renalytix.com
KidneyIntelX® Delivers Unprecedented Two-Year Real-World Outcomes in Diabetic Kidney Disease: No Comparable Risk Assessment Tool Exists
Renalytix announced results published in the peer-reviewed medical journal Diabetes, Obesity and Metabolism from its most comprehensive real-world evidence study for its FDA-approved KidneyIntelX.dkd test. The study, spanning 2,470 patients, demonstrates sustained risk-stratified improvements in kidney function and increased guideline-directed therapy uptake over two years.
2026-06
renalytix.com
Renalytix™ and Carna Health Partner to Solve Kidney Disease Crisis: Bridging the Existing Gap Between Population Screening and Precision Intervention
Renalytix PLC and Carna Health announced a partnership to transform how health systems identify, stratify, and manage chronic kidney disease and its interconnected cardiovascular-kidney-metabolic complications. This collaboration aims to bridge the gap between population screening and precision intervention in kidney disease.
2026-05
renalytix.com
Renalytix Announces Collaboration with Tempus to Advance Intelligent Risk Assessment in Diabetic Kidney Disease
Renalytix plc announced an agreement with Tempus AI, Inc. to make KidneyIntelX.dkd prognostic blood testing more widely available for eligible patients within Tempus's US network of healthcare institutions. This collaboration aims to accelerate the adoption of Renalytix's FDA-approved and Medicare-reimbursed test.
2025-09
dealroom.co
Renalytix raises $14M through AIM placing and retail offer | Dealroom News
Renalytix, a kidney-disease diagnostics company, raised approximately £10.5 million ($14.2 million) in gross proceeds through a placing, a subscription, and a WRAP Retail Offer. This funding aims to strengthen the company's balance sheet and support its operations.
2026-09
startupfundraising.com
Renalytix AI Funding: $46M Raised, Investors & Rounds
Renalytix AI has raised a total of $46 million in disclosed funding. The company is based in Salt Lake City, UT.
2026-07
renalytix.com
Renalytix welcomes new KDIGO 2024 CKD Guideline updates
Renalytix announced that its KidneyIntelX In-Vitro Diagnostic test has been included in the final KDIGO (Kidney Disease Improving Global Outcomes) 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease. The guideline highlights the role of risk prediction in guiding care for patients.
2024-03
mobihealthnews.com
Renalytix AI lands $29M
Renalytix AI, a developer of AI-enabled clinical diagnostics for kidney disease, secured $29 million in funding. This funding coincided with the company's announcement of being publicly traded on the London Stock Exchange.
2018-11

Frequently Asked Questions

Renalytix AI's primary product is KidneyIntelX.dkd, an AI-enabled in vitro diagnostic platform. It combines blood-based biomarkers, inherited genetics, and electronic health record data to generate a patient-specific risk score for progressive kidney function decline in adults with type 2 diabetes and early-stage chronic kidney disease (stages 1-3b).
KidneyIntelX.dkd helps clinicians identify patients at high, moderate, or low risk for rapid kidney function decline, enabling earlier, targeted interventions and personalized treatment plans. This precision medicine approach aims to slow disease progression, reduce costly events like dialysis starts, and improve overall kidney and cardio-metabolic outcomes.
KidneyIntelX.dkd has received FDA approval and Medicare reimbursement, and it is commercially available in the United States. It was also granted Breakthrough Device designation by the FDA, recognizing it as a breakthrough technology for kidney disease.
Clinical validation studies have shown KidneyIntelX.dkd to be more effective than standard-of-care markers in identifying high-risk patients. Real-world evidence demonstrates that its use leads to improved clinical decisions, increased prescriptions of guideline-directed therapies like SGLT2 inhibitors, and measurable reductions in patient risk trajectories over time.
Renalytix AI handles sensitive medical data and has achieved ISO 27001 certification for its Information Security Management System (ISMS), demonstrating its commitment to data security and compliance. The company also operates CLIA-certified and CAP-accredited laboratory facilities.
Renalytix AI collaborates with major healthcare systems like Mount Sinai Health System, insurance companies, and patient advocacy groups such as the National Kidney Foundation. They have also partnered with Tempus AI to expand access to KidneyIntelX.dkd testing and with Carna Health to integrate their diagnostic with a digital health platform for comprehensive CKD management.
The national price for KidneyIntelX.dkd under Medicare's Clinical Laboratory Fee Schedule is set at $950 per test. Renalytix AI aims to provide educational resources and practical support to clinicians, and they are working to secure broad insurance network coverage.
While currently focused on diabetic kidney disease, Renalytix AI plans to expand its platform to include screening, diagnosis, next-generation prognostic tools, and monitoring of treatment efficacy for a broader range of kidney diseases and comorbidities. They also aim to apply their AI-enabled diagnostics to improve patient characterization and enrich targeting for drug clinical trials.

Related Companies

AIRA Matrix is a healthcare AI company that develops cutting-edge artificial intelligence solutions for life sciences applications, with a strong emphasis on deep learning for medical image analysis. Their innovative products and services are designed to enhance diagnostic accuracy, improve workflow efficiency, and reduce turnaround times in pathology laboratories. The company provides diagnostic, prognostic, and […]

AI-LabTest is a secure, AI-powered digital health platform designed to help individuals understand their medical lab reports. The platform analyzes uploaded bloodwork or diagnostic results (in PDF, JPG, or TXT formats) and translates complex medical data into clear, personalized summaries. These summaries highlight key findings, potential implications, and practical next steps in patient-friendly language. The […]

Google DeepMind is a British-American artificial intelligence (AI) research laboratory and a subsidiary of Alphabet Inc.. Formed in April 2023 through the merger of DeepMind and Google AI’s Google Brain division, the company focuses on advancing artificial general intelligence (AGI) and developing AI systems for widespread public benefit and scientific discovery. Their work involves an […]

Tempus AI, Inc. is an American health technology company that utilizes data and artificial intelligence to deliver precision medicine services. The company was founded with the mission to bring data-driven precision medicine into routine care, initially focusing on oncology. Tempus has developed a platform that sequences tumor samples and employs AI models to assist physicians […]

SureMediks, a product of Rasimo Systems, LLC, is an AI-powered Clinical Operating System designed for longitudinal care, aiming to transform episodic healthcare into continuous, intelligent, and personalized patient management. The platform integrates patients, healthcare providers, clinical protocols, AI, connected medical devices, and electronic medical records into a unified ecosystem. SureMediks processes continuous real-world patient data […]

SigXA is a healthcare AI company that specializes in ambient AI medical scribe and assistant technology. Their platform captures clinician-patient conversations and converts them into structured clinical notes, which can then be pushed to Electronic Health Record (EHR) systems such as Epic, Cerner, Athenahealth, DrChrono, and eClinicalWorks. The AI is designed to understand medical context […]

AI Tool Finder
AI-powered search. Results may not be comprehensive.