Serena

VC Paris, France · Founded 2008

Serena is an operationally-driven venture capital firm that partners with early-stage startups from pre-seed to Series A, with a strong focus on applied AI, digital health, and deep technology transitions.

About Serena

Serena is a Paris-based generalist venture firm investing across consumer technology, B2B software, fintech, and selectively in health technology, with a portfolio that has historically included digital health and life-sciences-adjacent businesses. Stage focus is typically Series A and B, with checks in the EUR 2M to 10M range and the depth to lead. Healthcare exposure is opportunistic and most credible in digital health, applied AI for clinical workflows, and selectively life-sciences software; the firm operates a community-and-coach model that adds operating support to portfolio companies. Physician founders building European-anchored digital health, clinical AI, or B2B health software with credible commercial momentum are the right profile. Founders building therapeutics, devices, consumer wellness brands, or US-only commercial models without European center of gravity should pitch elsewhere. Geographic posture is European-led with French anchor and broader EU deal capacity. The realistic entry path is a warm introduction from a Serena portfolio CEO, a co-investing French seed fund, or a French ecosystem operator; the partners are responsive but prefer referred deals. Founders should arrive with traction signal, defended unit economics, and a credible European expansion narrative. Treat Serena as one of the more credible French generalist partners for software-shape healthcare companies and a thoughtful Series A lead, particularly for founders with French or broader European engineering centers of gravity.

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Healthcare AI tools backed by Serena

Tools made by companies in Serena's portfolio that we cover in the directory.

HeartFocus (V.1.1.1)
Deski
Cardiology AI
HeartFocus by Deski is an FDA-cleared AI-powered cardiac imaging software that enables healthcare professionals, including novices, to perform diagnostic-quality heart ultrasounds with real-time AI guidance.
Implicity ILR ECG Analyzer
Implicity
Cardiology AI
Implicity's AI-powered platform provides smart remote monitoring solutions for cardiac implantable electronic devices (CIEDs) and implantable loop recorders (ILRs), enhancing arrhythmia detection and optimizing clinical workflows.
SignalHF
Implicity
Cardiology AI
SignalHF by Implicity is an FDA-cleared AI algorithm that predicts heart failure hospitalizations within 30 days by analyzing data from various cardiac implantable electronic devices, enabling early intervention and personalized care.

Portfolio companies in our directory

Other portfolio companies

Companies in Serena's portfolio not currently in our directory.

Team

Marc Fournier
CEO & Co-founder
LinkedIn
Xavier Lorphelin
Managing Partner & Co-founder
LinkedIn
Philippe Hayat
Managing Partner & Co-founder
LinkedIn
Bertrand Diard
Partner - Associate - Serena Data Ventures
LinkedIn
Lu00e9a Zaslavsky
Partner at Racineu00b2
LinkedIn
Su00e9bastien Le Roy
Partner
LinkedIn

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Last updated 2026-05-06. Sourced from this fund's published materials.
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