Xcala

Angel Network Montevideo, Uruguay · Founded 2014

Catalyzes angel investment across Latin America and the Caribbean through training and networking.

About Xcala

Xcala is a Montevideo-based angel investment platform that catalyzes angel investing across Latin America and the Caribbean through training, networking, and capital deployment. Stage focus is pre-seed and seed with checks below $250k, and AI is not flagged as a primary focus. The platform’s distinctive value lies in its regional network of trained angel investors across multiple LatAm and Caribbean markets, which is a relatively rare structure in a region where angel investing has historically been less institutionalized than in the US or Europe. Healthcare interest spans digital health and consumer wellness within a broader technology mandate. The right founder for Xcala is a LatAm or Caribbean operator, often first-time founders or experienced operators on a second venture, building a digital health, telehealth, wellness, or healthcare software business with credible local market wedge and a willingness to engage with the angel network for hiring, customer introductions, and strategic advice. The wrong founder is a deep medtech or therapeutics team, a US-pedigreed founder using LatAm only as an engineering hub, or a Series A-plus company looking for an institutional lead. Intro paths run through Montevideo and Buenos Aires’s tight venture community, the broader regional angel networks including ANII in Uruguay, IAE Argentina, and the regional Endeavor cohorts, and through frequent co-investors and follow-on partners including LIV Capital, Polymath Ventures, NXTP Ventures, and the IDB Lab. Direct outreach through Xcala’s program is the standard entry. In the pitch, lead with the founding team’s depth, the unit economics in local currencies with realistic FX assumptions especially given Argentine and Uruguayan currency dynamics, and a credible regional expansion story since single-country small LatAm markets are rarely sufficient for Series A economics. Be specific about regulatory posture in your primary markets including ANMAT Argentina, MSP Uruguay, and analogous regimes. Show that you understand the difference between high-income concentrated urban markets and broader regional realities. Caveats include the syndicate dynamics typical of angel networks: diligence speed varies by which angels lead, term sheets are negotiated rather than templated, post-investment engagement depends on which specific angels engage, and the network’s check size alone will not finance a full seed round. Founders should plan parallel syndicate construction. For LatAm and Caribbean healthcare founders, Xcala is a useful regional angel network with structured training infrastructure.

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Team

Isabelle Chaquiriand
Executive Director
LinkedIn
Marcelo Roca
Executive Director
LinkedIn

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Last updated 2026-05-06. Sourced from this fund's published materials.
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