RayStation

by RaySearch Laboratories AB (publ)  · Based in Sweden → — Advancing cancer treatment through innovative and intelligent radiation therapy planning software.
Oncology Radiology

Enterprise
Documentation ProvidedRegulatory Status Disclosed

Overview

RayStation® is a flexible and innovative treatment planning system (TPS) developed by RaySearch Laboratories, designed to significantly enhance the efficiency and precision of radiation therapy for cancer patients. It is utilized by leading cancer centers worldwide to streamline complex planning processes and optimize treatment outcomes across a broad spectrum of modalities.

The system integrates advanced capabilities such as automated treatment planning driven by sophisticated machine learning and deep learning algorithms. This includes features like automated organ segmentation, plan-generating protocols, scripting, and the Plan Explorer module, which allows for rapid generation and comparison of multiple treatment plans. RayStation supports a wide array of treatment techniques, including 3D-CRT, IMRT, VMAT, electron therapy, helical TomoTherapy, CyberKnife, proton therapy, carbon-ion therapy, and Boron Neutron Capture Therapy (BNCT).

A core strength of RayStation lies in its adaptive therapy capabilities, featuring modules for dose tracking, deformable registration, and adaptive re-planning. This enables clinicians to account for anatomical changes during the course of treatment, ensuring continuous optimization and personalization of patient care. The system also boasts ultrafast and accurate dose computations, including Monte Carlo algorithms, which allow for efficient assessment of various treatment scenarios.

RayStation is designed for high connectivity and interoperability, compatible with most commercially available linear accelerators, Oncology Information Systems (OIS), and third-party Quality Assurance (QA) systems. Its data model is fully compatible with the DICOM standard, facilitating seamless import and export of DICOM RT objects. Furthermore, it supports standard protocols like HL7 and FHIR for data exchange with other hospital information systems, including tight integration with RaySearch’s own oncology information system, RayCare.

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Key Features

  • Automated Treatment Planning (Machine Learning & Deep Learning)
  • Adaptive Radiation Therapy (Dose Tracking, Deformable Registration, Re-planning)
  • Multi-Criteria Optimization (MCO)
  • Support for diverse treatment machines (Linacs, Proton, Carbon-ion, TomoTherapy, CyberKnife)
  • Fast and Accurate Dose Computations (Monte Carlo)
  • Deep Learning Segmentation
  • Plan Explorer for treatment plan comparison
  • Scripting for workflow automation (IronPython, CPython)
  • Brachytherapy Planning Support
  • Upright Treatment Planning Support

Use Cases

  • Comprehensive radiation therapy treatment planning
  • Adaptive radiation therapy for anatomical changes
  • Automated organ and target volume segmentation
  • Dose tracking and accumulation
  • Quality assurance for treatment plans
  • Research and data analysis in radiation oncology

What Physicians Need to Know

Evidence Base
RayStation incorporates advanced algorithms, including machine learning and deep learning, for automated treatment planning and organ segmentation, with models trained and evaluated on curated clinical data. It supports a wide range of treatment techniques (e.g., photon, electron, proton, carbon ion, brachytherapy) and optimization algorithms (e.g., IMRT, VMAT, SBRT, SRS, TomoTherapy, CyberKnife, PBS). The system offers biological optimization and evaluation tools, utilizing biological models for TCPs and NTCPs, and Relative Biological Effectiveness (RBE) scaling for different modalities. Multi-criteria optimization (MCO) is a core feature, allowing clinicians to explore Pareto-optimal treatment plans and balance conflicting clinical goals in real-time. Automated planning algorithms, such as ECHO (developed by Memorial Sloan Kettering Cancer Center), are integrated to optimize plans based on predefined clinical protocols.
Clinical Validation Studies
Dose calculation algorithms, including Monte Carlo (MC) and collapsed cone (CC), have undergone validation studies for various treatment machines like CyberKnife M6, demonstrating dose differences generally within u00b11%. The Monte Carlo dose algorithm has also been validated using realistic animal tissue phantoms and water breast phantoms, showing excellent agreement with measured doses. Integration of RayStation's AI-based auto-contouring with other treatment planning systems (TPS) has been clinically validated, showing significant reductions in contouring time and improved consistency. Retrospective studies have evaluated the use of RayStation's scripting for automated radiotherapy plans, indicating improved dose conformity and reduced organ-at-risk (OAR) exposure. Robust optimization, introduced in RayStation in 2014, is a standard tool in ion therapy and is gaining traction in photon planning.
Alert Fatigue Management
While RayStation generates warnings related to safe operation and data integrity (e.g., during DICOM import/export or when setting safety parameters), there is no explicit feature described for 'alert fatigue management' within the system itself. However, the system's scripting capabilities offer flexibility for clinics to customize workflows, which could indirectly contribute to managing alert volume by automating routine tasks or routing non-critical communications.
Override Rate Data
RayStation allows users to define overrides for various attributes, such as dose rates for setup beams and material overrides in dose computation. The system's instructions emphasize careful review of these overrides to ensure correct input for dose calculations. Specific data on the frequency or rate of these overrides is not publicly available or detailed in the provided information.
Clinical Workflow Integration
RayStation offers seamless integration with various treatment delivery systems, including Accuray's CyberKnife, TomoTherapy, and Radixact Systems. It boasts high connectivity with most commercially available linear accelerators, Oncology Information Systems (OIS), and third-party Quality Assurance (QA) systems, leveraging the DICOM standard for comprehensive data exchange. Custom scripting capabilities (e.g., Python, C#) enable automated data exchange and integration with other TPS for tasks like AI-based auto-contouring, enhancing efficiency and consistency. Enhanced integration with RayCare, RaySearch's OIS, supports adaptive workflows and complex information management. Automated interfaces with surface guidance systems like Vision RT's MapRT provide clearance maps to guide safe non-coplanar treatment planning. Workflow automation is a key design principle, utilizing protocols, scripting, and machine learning to streamline plan generation and optimization.
Decision Audit Trail
While RayStation itself, as a treatment planning system, does not explicitly detail an internal 'decision audit trail' feature in the provided information, its close integration with RayCare, RaySearch's Oncology Information System, suggests that treatment planning decisions, especially within adaptive therapy workflows, would be part of a broader, structured audit trail managed by the OIS. RayCare is designed to automatically document decisions and notes, such as those from tumor board meetings. Scripting functionality within RayStation can also be used to log and track specific actions or data.
Physician Tip

To maximize the benefits of RayStation, physicians should actively engage with its multi-criteria optimization (MCO) module to explore various treatment plan trade-offs and make informed decisions that best balance tumor coverage and organ-at-risk sparing. Leverage the system's extensive automation tools, including scripting, protocols, and templates, to enhance planning efficiency and consistency for routine cases, freeing up time for more complex scenarios and patient consultations. Fully utilize the adaptive therapy capabilities for dose tracking and replanning to dynamically adjust to anatomical changes during the course of treatment, ensuring optimal patient outcomes. Always review and approve auto-generated contours and treatment plans, maintaining clinical oversight while benefiting from the system's productivity enhancements. Exercise caution and thoroughly review any user-defined overrides for material properties or safety parameters, particularly in complex particle therapy planning, to ensure accuracy and patient safety.

RayStation is designed for extensive interoperability, offering high connectivity with a wide array of linear accelerators, Oncology Information Systems (OIS), and third-party Quality Assurance (QA) systems, all facilitated by its full compatibility with the DICOM standard for seamless data exchange. Key integrations include Accuray treatment delivery systems (CyberKnife, TomoTherapy, Radixact) and RaySearch's own OIS, RayCare, which together provide a comprehensive ecosystem for radiation oncology workflow management and adaptive therapy. Its robust scripting capabilities (Python, C#) allow for custom integrations with other treatment planning systems, such as automated AI-based auto-contouring with Eclipse, and enable flexible data exchange beyond standard DICOM. Furthermore, automated interfaces with surface guidance systems like Vision RT's MapRT enhance planning safety by providing real-time clearance maps for complex non-coplanar treatments.

Details

Category Clinical Decision Support & Reference, Radiology & Imaging AI
Pricing Enterprise
  • Custom pricing based on specific clinic needs and modules; RayCare Flow integration available via subscription model at $9,000 (US) per RayStation planning installation annually
DeploymentOn premise
Mobile AppNone
API Available Yes
Data Export Yes
LanguagesEnglish
Training Yes
Target SizeSolo to large health systems
Compliance
BAA AvailableUnknown AI-estimated
HIPAA CompliantUnknown AI-estimated
FDA Status Cleared AI-estimated — 510(k) number: K222312 (for RayStation 12A)
Integrations
EHR Not specified
Specialties Oncology, Radiology

Social Proof

Customers1000+ cancer centers in 44 countries (as of Jan 2024)
Notable
Massachusetts General HospitalWest German Proton Therapy Center EssenPrincess Margaret Cancer CentreMoffitt Cancer CenterChina Japan Friendship HospitalUniversity of Tokyo HospitalYonsei Cancer Center

Support & Reliability

Training Provided Yes

What the Web Says

RayStation is a highly regarded radiation therapy treatment planning system, particularly favored by medical physicists and radiation oncologists for its advanced capabilities and intuitive interface. It aims to deliver an unmatched user experience and leading functionality, with a strong focus on improving treatment quality and speeding up planning processes. The system is designed for extensive interoperability with various linear accelerators, Oncology Information Systems (OIS), and third-party Quality Assurance (QA) systems.

Overall: Positive

Strengths

  • Intuitive and user-friendly interface, often described as cleaner and easier to adapt than competitors.
  • Highly customizable and flexible, especially with Python scripting capabilities, allowing for automation and streamlined workflows.
  • Advanced features like Multi-Criteria Optimization (MCO), Plan Explorer, deformable registration, and 4D adaptive radiation therapy.
  • Ultrafast and accurate dose computations, including Monte Carlo algorithms, which are particularly advantageous for advanced techniques and tissue heterogeneities.
  • Seamless integration with various treatment delivery systems and high connectivity with most commercially available linear accelerators and OIS.
  • Strong focus on continuous development and innovation, including machine learning for automated segmentation and treatment planning.

Limitations

  • Can be expensive, especially with additional licenses and features.
  • Learning curve can be steep for new users, though some find it easier than competing systems.
  • Potential hiccups when exporting data to non-RaySearch systems, particularly Varian machines, due to vendor ecosystems.
  • Some users have reported that plan review can be clumsy, lacking quick ways to see if clinical goals are met.
  • Optimization can be slow in some complex cases, such as H&N planning with many constraints.
  • Concerns about integration complexity and training costs for hospital administrators, despite technical excellence.

Based on reviews from: Reddit, RaySearch Laboratories (Customer Stories), Physician AI Tools, PubMed, American Society for Radiation Oncology (ASTRO), MDPI, Google Groups

Last updated: 2026-07-19

Ratings & Reviews

No reviews yet. Be the first to review this tool!

Rate RayStation

Clinical Value
Ease of Use
Integration
Support & Docs
Value for Money

Press & Coverage

RaySearch Laboratories
RaySearch releases RayStation v2026
RayStation v2026 introduces enhanced support for reirradiation, integrated patient-specific quality assurance, expanded automation, and improvements in particle therapy. This version helps clinics manage advanced treatments with greater efficiency and confidence.
2026-07
RaySearch Laboratories
RaySearch to present automation, speed, and analytics advancements at AAPM 2026
RaySearch will showcase advancements in automation, speed, and analytics for cancer treatment at AAPM 2026, highlighting innovations in RayStation, RayCare, and RayIntelligence.
2026-07
RaySearch Laboratories
Preliminary results for the second quarter of 2026
RaySearch Laboratories announced its preliminary results for the second quarter of 2026.
2026-07
RaySearch Laboratories
First online adaptive treatment on TrueBeam using RayStation and RayCare
Iridium Network in Belgium successfully completed its first online adaptive radiation treatment using RayStation and RayCare on a Varian TrueBeam linear accelerator. This milestone demonstrates the ability to perform adaptive radiotherapy on commonly installed machines.
2026-05
RaySearch Laboratories
Institut Hartmann selects RayStation and RayCare
Institut de Radiothu00e9rapie et de Radiochirurgie Hartmann in France has chosen RayStation and RayCare to enhance clinical workflows across its radiotherapy environment, marking RaySearch's first RayCare sale in France.
2026-04
RaySearch Laboratories
RaySearch publishes Annual Report for 2025
RaySearch Laboratories published its Annual Report and Sustainability Report for the financial year 2025, highlighting record net sales and important clinical milestones despite macroeconomic uncertainty.
2026-04
PR Newswire
RayStation used for pioneering clinical milestone at Helsinki University Hospital - first treatment with accelerator-based BNCT in Europe
RayStation was utilized in the first European treatment with accelerator-based Boron Neutron Capture Therapy (BNCT) at Helsinki University Hospital, marking a significant clinical advancement.
2025-06
GE HealthCare
GE HealthCare debuts AI-supported solution, designed to improve and shorten the radiation therapy workflow, at ASTRO 2025
GE HealthCare unveiled updates to its Intelligent Radiation Therapy (iRT) solution at ASTRO 2025, which, when integrated with RayStation, has reduced simulation to treatment planning time from seven days to seven minutes.
2025-09

Videos

Product demos, reviews, and walkthroughs for RayStation.

View all on YouTube

Frequently Asked Questions

RayStation provides advanced tools like automated treatment planning, deep learning segmentation for auto-contouring, and multi-criteria optimization (MCO) to streamline the planning process. These features aim to increase efficiency, improve plan consistency, and allow physicians to explore various treatment options and tradeoffs in real-time, ultimately supporting informed clinical decisions.
RayStation has received FDA 510(k) clearance in the USA for its machine learning functionalities, including automated organ segmentation and planning. Additionally, it complies with the Medical Device Regulation (MDR) 2017/745 in the EU, and regulatory information is provided in its Instructions for Use.
Key competitors in the treatment planning system (TPS) market include Varian's Eclipse and Philips Healthcare's Pinnacle. Oncology Information Systems (OIS) like Mosaiq and ARIA also offer overlapping functionalities in treatment planning and workflow management.
Physicians should be aware that dose calculation algorithms can lead to discrepancies between Pareto optimal and final deliverable plans, requiring careful clinical judgment. Additionally, while highly automated, complex or novel cases may still necessitate significant manual oversight and expert review.
The MCO module allows physicians and planners to continuously explore tradeoffs between conflicting clinical goals, such as target coverage and organ-at-risk sparing, in real-time. This interactive approach facilitates more informed and structured decision-making, potentially reducing iterative plan adjustments and increasing physician engagement in the planning process.
RayStation integrates AI and deep learning for tasks like automated organ segmentation and generating treatment plans, significantly reducing manual contouring and planning time. This automation aims to improve plan consistency, free up clinical staff for more complex patient care, and enable the generation of high-quality, personalized plans more efficiently.
While specific pricing for RayStation itself is not publicly detailed, RaySearch products often utilize a subscription model. For example, RayCare Flow, which integrates with RayStation, is offered with an annual subscription fee per installed RayStation planning system, typically including installation, training, and support. This suggests a service-oriented pricing approach rather than a one-time purchase.

Related Tools

Cortex
Cortex
Clinical Decision Support & Reference
Cortex Workspace is a secure, HIPAA-compliant AI platform designed to streamline healthcare workflows and enhance decision-making for physicians.
SureMediks ProView
SureMediks (Rasimo Systems, LLC)
Clinical Decision Support & Reference
SureMediks is an AI-powered clinical decision support and metabolic health platform that automates care workflows for specialists, providing AI-generated patient summaries, automated chart review, and real-time biometric alerts.
SOAP Health
SOAP Health
Clinical Decision Support & Reference
SOAP Health is a Florida-based startup transforming patient intake with AI-powered diagnosis, offering a comprehensive solution that improves diagnosis accuracy and empowers patients and physicians.
Oxipit ChestLink
Oxipit (part of Sectra group)
Clinical Decision Support & Reference
Oxipit ChestLink is the world's first CE Class IIb-certified autonomous AI application for healthy chest X-ray reporting, capable of identifying normal studies with 99.9% sensitivity. It automates the reporting of normal chest X-rays, reducing radiologist workload and improving efficiency.
KATE AI
Mednition
Clinical Decision Support & Reference
KATE AI is a nurse-built clinical decision support tool for emergency departments that analyzes incoming patients in real-time to flag high-risk cases that standard acuity scoring might miss. It has supported over 5,000,000 patient visits, helping emergency teams deliver safer, faster, and more informed care.
MCG Health
MCG Health
Clinical Decision Support & Reference
MCG Health provides industry-leading evidence-based guidance and technologies to optimize health outcomes, drive operational efficiency, and achieve cost savings. Their solutions are utilized by thousands of hospitals, a majority of U.S. health plans, and various government health programs.

See all Clinical Decision Support & Reference tools →

More from RaySearch Laboratories AB (publ)

RayCare
RaySearch Laboratories AB (publ)
EMR / EHR Systems
RayCare is an innovative oncology information system (OIS) from RaySearch Laboratories, designed to streamline and automate workflows across all oncology disciplines, from patient registration to treatment delivery and follow-up. It integrates with various hospital systems and supports advanced features like adaptive radiation therapy and comprehensive patient management.
RayStation 11B
RaySearch Laboratories AB (publ)
Oncology AI
RayStation 11B by RaySearch Laboratories is an advanced treatment planning system for radiation oncology, featuring improved dose calculation accuracy, adaptive therapy capabilities, and AI-powered machine learning for automated planning and segmentation.
RayStation 12A
RaySearch Laboratories AB (publ)
Oncology AI
RayStation 12A is an AI-driven treatment planning system for radiation oncology, offering deep learning segmentation, multi-criteria optimization, and adaptive therapy for various cancer treatment techniques.
RayStation 2023B
RaySearch Laboratories AB (publ)
Oncology AI
RayStation 2023B is a comprehensive AI-powered treatment planning system for radiation therapy, developed by RaySearch Laboratories. It offers advanced features like automated planning, adaptive therapy, multi-criteria optimization, and support for various treatment techniques to improve cancer care.

View company profile →

Suggest an Edit → | Last Verified: 2026-04-19 | First Added: 2026-04-19
AI Tool Finder
AI-powered search. Results may not be comprehensive.