Products

VX1+
Volta Medical
Cardiology AI
AI-powered software that assists electrophysiologists in real-time identification of abnormal electrograms during cardiac ablation procedures for atrial fibrillation and atrial tachycardia.
VX1
Volta Medical
Cardiology AI
Volta Medical's VX1 is an FDA-cleared AI software that assists cardiac electrophysiologists in real-time identification of dispersed electrograms during atrial fibrillation and atrial tachycardia ablation procedures.
Volta AF-Xplorer II
Volta Medical
Cardiology AI
Volta AF-Xplorer II is an AI-powered digital companion from Volta Medical, designed to assist electrophysiologists in the real-time identification of spatio-temporal dispersed electrograms during complex atrial fibrillation and atrial tachycardia ablation procedures.

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About Volta Medical

Volta Medical is a pioneering health technology company that develops artificial intelligence (AI) software solutions to assist cardiac electrophysiologists in treating complex cardiac arrhythmias, primarily atrial fibrillation (AF) and atrial tachycardia. Their core mission is to enhance patient care by providing state-of-the-art, data-driven medical devices trained on extensive databases of procedural data.

The company’s flagship product, VOLTA AF-Xplorer (and its successor, AF-Xplorer II), is an AI-driven decision-support software designed to provide real-time identification and annotation of specific abnormal electrograms, known as spatio-temporal dispersed electrograms, on 3D anatomical and electrical maps of the heart during catheter ablation procedures. This technology aims to improve the precision and consistency of ablations, potentially leading to optimized clinical outcomes for patients and reducing the need for repeat treatments. The VOLTA AF-Xplorer system has received both CE Mark approval in Europe and 510(k) clearance from the U.S. FDA.

Volta Medical’s solutions are engineered for versatility, integrating seamlessly with leading AF mapping and recording systems and compatible with common ablation modalities. Recent clinical trials, such as TAILORED-AF, have demonstrated improved freedom from AF in patients treated with AI-guided ablation compared to conventional anatomical ablation. The company also focuses on R&D and clinical research to further enhance treatment strategies and is expanding its market reach, particularly in the US healthcare sector, through partnerships with leading centers and companies like GE HealthCare.

Focus Areas

Cardiac arrhythmias Atrial Fibrillation (AFib) Persistent Atrial Fibrillation Atrial Tachycardia (AT) Interventional Cardiology Electrophysiology Cardiac Ablation Procedures Real-time Electrogram Analysis Spatio-temporal Dispersion Mapping AI Decision-Support Software

Business Intelligence

Key InvestorsVensana Capital, Lightstone Ventures, Gilde Healthcare, La French Tech, Groupe Pasteur Mutualité
PartnershipsGE HealthCare (for integration of Volta AF-Xplorer AI solution with GE's Prucka 3 digital platform and CardioLab EP recording system), Abbott Laboratories (EnSite X mapping system integration), Biosense Webster (Octaray multi-polar mapping catheter compatibility), Medtronic (Sphere-9 mapping and ablation catheter compatibility)
TechnologyAI-based software solutions, machine learning and deep learning algorithms, real-time cue-giving interface, VoltaPlex data collection and enrichment ecosystem, trained on extensive proprietary databases of AF electrograms, cloud-native (implied by software solution and data processing)
FDA Clearances2 cleared products (estimated)

What Physicians Need to Know

Cardiac Arrhythmias & AFib Specialization
Volta Medical specializes in the treatment of complex cardiac arrhythmias, with a strong focus on Atrial Fibrillation (AFib), including persistent AFib, and Atrial Tachycardia (AT). They aim to improve outcomes for patients suffering from these conditions.
Interventional Cardiology & Electrophysiology
The company develops AI-driven solutions to assist electrophysiologists during interventional cardiology procedures, specifically cardiac ablation procedures, by providing real-time insights into the heart's electrical activity.
AI Decision-Support Software
Volta Medical's flagship product, Volta AF-Xploreru2122 II, is a digital AI companion that leverages artificial intelligence, including machine and deep learning algorithms, to provide real-time decision support to cardiologists during ablation procedures.
Real-time Electrogram Analysis
Their technology is designed for the real-time identification and analysis of spatio-temporal dispersed electrograms (EGMs), which are indicative of arrhythmia drivers. This goes beyond traditional visual interpretation.
Spatio-temporal Dispersion Mapping
A core specialization is the mapping of spatio-temporal dispersion areas within the heart, which are believed to be the root cause of complex arrhythmias like AFib. The AF-Xploreru2122 II identifies and annotates these unique abnormalities on 3D anatomical and electrical maps.
Improved Ablation Outcomes
Clinical trials, such as the TAILORED-AF and RESTART trials, have demonstrated that AI-guided ablation procedures using Volta's technology can lead to significantly higher rates of freedom from AFib and other atrial arrhythmias compared to standard approaches, particularly in complex and persistent AFib cases.
Physician Tip

For physicians, Volta Medical's AI solutions offer enhanced precision in identifying arrhythmia drivers, potentially leading to more effective and durable ablation outcomes, especially for challenging persistent AFib cases. The real-time guidance can standardize and optimize ablation strategies, reducing reliance on subjective interpretation and potentially improving procedural efficiency. Consider integrating Volta AF-Xploreru2122 II to augment your existing mapping systems for a data-driven approach to targeting complex arrhythmias and improving patient quality of life. The technology is designed to assist in complex cases, including those with recurrent AF after previous ablations.

Volta Medical's AF-Xploreru2122 II is engineered for versatility and integrates seamlessly with leading AF mapping and recording systems (e.g., CARTO 3, ENSITE X, AFFERA, OPAL HDx) and is compatible with most common ablation modalities, including PFA catheters. They have a strategic partnership with GE HealthCare, allowing for integration with the GE HealthCare CardioLab AltiX AI.i EP recording platform for a unified workspace and enhanced workflow efficiency.

Products by Volta Medical

4 products in the directory

VX1+
Volta Medical
Cardiology AI
AI-powered software that assists electrophysiologists in real-time identification of abnormal electrograms during cardiac ablation procedures for atrial fibrillation and atrial tachycardia.
VX1
Volta Medical
Cardiology AI
Volta Medical's VX1 is an FDA-cleared AI software that assists cardiac electrophysiologists in real-time identification of dispersed electrograms during atrial fibrillation and atrial tachycardia ablation procedures.
Volta AF-Xplorer II
Volta Medical
Cardiology AI
Volta AF-Xplorer II is an AI-powered digital companion from Volta Medical, designed to assist electrophysiologists in the real-time identification of spatio-temporal dispersed electrograms during complex atrial fibrillation and atrial tachycardia ablation procedures.
Volta AF-Xplorer
Volta Medical
Cardiology AI
Volta AF-Xplorer is an AI-assisted mapping and decision-support system for electrophysiology ablation procedures, automatically detecting dispersed electrograms in real-time to guide treatment for complex atrial fibrillation and atrial tachycardia.

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Press & Coverage

Volta Medical (via PRNewswire)
Volta Medical Announces Activities at Heart Rhythm Society 2026 in Chicago, IL, USA
Volta Medical announced its participation in the Heart Rhythm Society 2026 Annual Meeting, featuring presentations and demonstrations of its AI-enhanced mapping and clinical evidence for treating complex cardiac arrhythmias.
2026-04
Volta Medical (via PRNewswire)
Volta Medical's RESTART Trial Shows Promising Findings for AI Solutions in Recurrent Atrial Fibrillation
The RESTART trial demonstrated that Volta Medical's AI solution achieved 83% freedom from atrial fibrillation at 12 months in patients with recurrent AF, a population that historically has suboptimal outcomes.
2026-02
Diagnostic and Interventional Cardiology
Volta Medical and GE HealthCare Announce Successful U.S. Launch of Joint AI-Driven Electrophysiology Solutions
Volta Medical and GE HealthCare successfully launched their joint AI-driven electrophysiology solutions in the U.S., aiming to enhance performance and streamline workflows for electrophysiologists treating atrial fibrillation.
2025-11
Volta Medical
Volta Medical Brings Volta AF-Xploreru2122 II to the U.S., Ushering in a New Era of AI in Ablation for Complex Atrial Fibrillation
Volta Medical announced the U.S. launch of its next-generation AI solution, AF-Xplorer II, designed to simplify real-time assessment of complex atrial fibrillation and improve patient outcomes.
2025-11
Volta Medical (via PR Newswire)
Volta Medical Announces U.S. Label Expansion for Volta AF-Xploreru2122 to Include Pivotal TAILORED-AF Clinical Trial Data
Volta Medical secured a significant U.S. label expansion for its Volta AF-Xplorer system, now including groundbreaking clinical data from the TAILORED-AF trial, which demonstrated improved long-term outcomes for persistent AF patients.
2025-06
EP Lab Digest
Volta Medical Artificial Intelligence-guided Cardiac Ablation Procedure Improves Treatment of Atrial Fibrillation
Volta Medical announced the publication of the landmark TAILORED-AF clinical trial, showing that AI-guided cardiac ablation combined with pulmonary vein isolation was superior to standard care for persistent atrial fibrillation.
2025-02
Volta Medical
Volta Medical Enters into Joint Development Agreement with GE HealthCare to Enhance Arrhythmia Procedures with AI-Driven Electrophysiology Technologies
Volta Medical and GE HealthCare announced a Joint Development Agreement to integrate Volta's AI solution, Volta AF-Xplorer, with GE HealthCare's Prucka 3 and CardioLab EP Recording system to improve atrial fibrillation procedures.
2024-07
Volta Medical
Volta Medical Featured in Latest Consensus Statement from Leading International Cardiac Electrophysiology Societies on Atrial Fibrillation Ablation
Volta Medical's AI companion technology and the TAILORED-AF clinical trial were highlighted in a consensus statement from leading cardiac electrophysiology societies, focusing on advancements in atrial fibrillation treatment.
2024-05

Frequently Asked Questions

Volta Medical's core technology is the AF-Xploreru2122 II AI-driven software, designed to assist electrophysiologists in real-time identification of spatio-temporal dispersed electrograms (EGMs) during cardiac ablation procedures for AFib and AT. This AI companion analyzes 3D anatomical and electrical maps of the atria to pinpoint specific abnormal EGM regions, which are suspected drivers of these arrhythmias.
The landmark TAILORED-AF clinical trial demonstrated that an AI-guided procedure for persistent AF, combined with conventional pulmonary vein isolation (PVI), resulted in significantly better outcomes than PVI alone. Specifically, 88% of patients in the AI-guided group achieved freedom from AF symptoms within one year, compared to 70% in the PVI-only group.
Volta Medical's AF-Xploreru2122 II (and its previous iterations) has received U.S. FDA 510(k) clearance and European CE Mark approval. These clearances confirm that the software meets the necessary safety and performance standards for use in interventional cardiac electrophysiology procedures in both the United States and the European Union.
Volta Medical's AF-Xploreru2122 II is designed for seamless integration with leading AF mapping and recording systems, including GE HealthCare's CardioLabu2122 AltiX AI.i EP recording system. A key partnership with GE HealthCare aims to enhance arrhythmia procedures by combining advanced signal clarity with AI-driven insights, streamlining workflows and providing a unified workspace for electrophysiologists.
Yes, the RESTART trial demonstrated positive outcomes for patients with recurrent atrial fibrillation and isolated pulmonary veins who underwent ablation using Volta's AI solution. The trial reported an 83% rate of freedom from AF at 12 months after a single AI-guided repeat ablation procedure.
Volta Medical has demonstrated strong financial stability, having secured u20ac36 million (approximately $38.1 million) in Series B funding, bringing their total capital raised to over u20ac70 million (approximately $74.2 million). This significant investment, led by Vensana Capital with co-investment from Lightstone Ventures and Gilde Healthcare, supports ongoing product development, clinical trials, and global commercialization efforts.
Volta Medical focuses on providing practical, interoperable tools designed for seamless integration with existing EP lab equipment to ensure ease of adoption and workflow efficiency. They have also created the 'AI for Persistent AF Care' program to offer resources and education about AF and AI-guided treatment to patients, caregivers, and providers.

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