VX1
Overview
VX1 by Volta Medical is an artificial intelligence-based decision-support software designed to assist cardiac electrophysiologists during catheter ablation procedures. The system is built for use in electrophysiology (EP) laboratories and clinical environments where complex cardiac arrhythmias, such as persistent atrial fibrillation (AF) and atrial tachycardia (AT), are diagnosed and treated.
The software integrates into the clinical workflow by analyzing intracardiac electrograms (EGMs) in real time. It automatically identifies and annotates areas of spatiotemporal dispersion, which are localized electrical abnormalities that can act as drivers for arrhythmias. By providing real-time visual annotations on 3D anatomical and electrical maps of the human atria, VX1 helps operators locate specific regions of interest.
Notable capabilities of VX1 include:
- Real-Time Dispersion Detection: Employs machine learning and deep learning algorithms to identify and tag dispersed electrograms during mapping.
- Broad Compatibility: Integrates with major 3D mapping systems, EP recording systems, and standard multipolar mapping catheters.
- Booster Mode: Allows operators to increase software sensitivity during slow atrial fibrillation or atrial tachycardia to refine signal analysis.
- Standardized Mapping: Offers a consistent, data-driven approach to mapping, reducing operator-dependent variability in identifying complex atrial signals.
Reviewed by Pouyan Golshani, MD — Interventional Radiologist
Key Features
- AI-guided real-time identification of dispersed electrograms (EGMs)
- Assists cardiologists during AFib and atrial tachycardia ablation procedures
- Analyzes 3D anatomical and electrical maps of human atria
- Compatible with most EP recording, 3D navigation systems, and mapping catheters
- Designed to reduce inter-operator variability and standardize outcomes
- Provides cycle length estimation from electrograms
- Booster mode for increased sensitivity during AT or slow AF
Use Cases
- Assisting electrophysiologists during catheter ablation for persistent atrial fibrillation
- Improving outcomes in complex atrial fibrillation and atrial tachycardia treatments
- Real-time identification of arrhythmia drivers during procedures
- Standardizing electrogram-based ablation outcomes across operators and centers
What Physicians Need to Know
VX1 is designed to assist electrophysiologists by providing real-time, objective identification of dispersed electrograms during atrial fibrillation and atrial tachycardia ablation procedures. This can help standardize EGM-based ablation outcomes, potentially reducing inter-operator variability and improving the efficacy of procedures by more precisely pinpointing optimal ablation locations. While the clinical significance for catheter ablation of atrial arrhythmias has not yet been fully established by clinical investigations, ongoing trials like TAILORED-AF aim to demonstrate its impact.
VX1 is built for broad compatibility, working with most commercially available multipolar catheters and various EP recording and 3D navigation systems. This flexibility allows for seamless integration into existing electrophysiology lab setups and workflows. The VX1+ iteration offers enhanced integration with systems like Abbott Laboratories' EnSite X mapping system and compatibility with Biosense Webster's Octaray multi-polar mapping catheter.
Details
| Category | Cardiology AI, Surgical AI |
| Pricing | Contact for pricing |
| Deployment | Software integrated with existing electrophysiology (EP) lab mapping and recording systems. |
| Compliance | |
| BAA Available | Unknown AI-estimated |
| HIPAA Compliant | Unknown AI-estimated |
| FDA Status |
1 AI-estimated The VX1 software is U.S. FDA 510(k) cleared (K201298) and European CE Mark approved. It assists operators in the real-time manual annotation of 3D anatomical and electrical maps of human atria for the presence of multipolar intra-cardiac atrial electrograms exhibiting spatiotemporal dispersion during atrial fibrillation or atrial tachycardia. |
| Integrations | |
| EHR | Not specified |
| Specialties | Cardiology |
What the Web Says
Volta Medical's VX1 is an AI-powered software designed to assist electrophysiologists in real-time during atrial fibrillation (AFib) ablation procedures. It aims to standardize the identification of abnormal electrograms (EGMs) and improve treatment outcomes for patients with persistent AFib. The software has received FDA clearance and CE mark, and initial studies suggest it can lead to high rates of freedom from AFib after ablation.
Overall: PositiveStrengths
- Reproduces expert-physician EGM analysis, standardizing abnormal electrogram detection across different operators and centers.
- Assists physicians in real-time identification of specific abnormal electrograms (dispersed EGMs) during ablation procedures.
- Shows promise in potentially reducing inter-operator variability in procedural data analysis.
- May lead to improved patient outcomes with high rates of freedom from AFib and atrial arrhythmia after one year.
- Compatible with most readily available multipolar catheters and mapping technologies.
- Intuitive and user-friendly interface with visual and sound cues for operators.
Limitations
- Clinical significance of utilizing VX1 to identify areas with spatiotemporal dispersion for catheter ablation has not been fully established by clinical investigations.
- The ongoing TAILORED-AF trial is expected to confirm the potential of the technology and establish it as a new standard of care, indicating that this is still a developing area.
- No specific negative reviews from physicians, healthcare IT, tech reviewers, Reddit, G2, or Capterra were found in the search results.
Based on reviews from: PRNewswire, BioWorld, BioSpace, Cardiac Rhythm News, Medium, Journal of Cardiovascular Electrophysiology (via PMC)
Last updated: 2026-07-19
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Press & Coverage
Videos
Product demos, reviews, and walkthroughs for VX1.
ABLATION for ATRIAL FIBRILLATION: Watch a live procedure!
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