BRUKER DALTONICS

Billerica, Massachusetts, U.S.A.  All United States companies → — Founded 1960
Medical Device / Hardware Point-of-Care Diagnostics
Infectious Disease Laboratory Medicine
Lab & Diagnostics
Public (Bruker Corporation is publicly traded on Nasdaq)
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Products

MALDI BIOTYPER CA (MBT-CA) SYSTEM
BRUKER DALTONICS
Lab & Diagnostics
The Bruker MALDI Biotyper CA System is an FDA-cleared in vitro diagnostic mass spectrometry system for rapid, accurate, and reliable identification of microorganisms from human specimens in clinical microbiology laboratories.
Contact vendor for pricing

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About BRUKER DALTONICS

Bruker Daltonics, an operating company of Bruker Corporation, is a leading developer and provider of innovative life science tools based on mass spectrometry. The company designs, manufactures, and markets a broad array of products to meet the growing needs of diverse customers, including pharmaceutical, biotechnology, proteomics, and molecular diagnostics companies, as well as academic institutions and government agencies. Their offerings include high-performance mass spectrometers, software, and accessories that enhance the productivity and capabilities of analytical operations. Bruker Daltonics is dedicated to advancing molecular exploration, equipping scientists with cutting-edge tools to drive discoveries in life sciences and biotechnology.

For physicians, Bruker Daltonics’ technologies are crucial in areas such as clinical microbiology and molecular diagnostics, including rapid pathogen identification platforms like the MALDI Biotyper. Their mass spectrometry solutions are also applied in clinical diagnostics, drug metabolism studies, and biomarker discovery and identification. The company emphasizes research-use instruments and software designed to deliver precise, reliable data to inform scientific decisions, supporting advancements in post-genomic disease research and drug discovery. Recent developments include expanding multiomics capabilities and integrating AI-lab automation and software for enhanced workflows.

Bruker Daltonics’ diverse technology platforms integrate various mass spectrometry systems, such as MALDI-TOF, FTMS, and ESI-Q-q-TOF, with automated sample processing systems and productivity-enhancing software for life science applications. They are also involved in supplying systems for substance and pathogen detection in security, defense, and anti-terrorism. The company’s focus on innovation extends to spatial biology, proteomics, and multiomics, with platforms like the timsTOF series enabling 4D-Proteomics™ and SpatialOMx® for deeper insights into biological systems.

Focus Areas

mass spectrometry analytical and diagnostic solutions life science molecular research applied and pharma applications microscopy and nanoanalysis industrial applications cell biology preclinical imaging clinical phenomics and proteomics research clinical microbiology spatial biology single-cell analysis multiomics proteomics metabolomics lipidomics infectious disease diagnostics food safety environmental monitoring forensics industrial quality control drug discovery

Business Intelligence

TechnologyMass spectrometry (MALDI-TOF, MALDI-TOF/TOF, ESI, ion trap, ESI-TOF, ESI-qTOF, UHR-TOF, FTMS, ICP-MS, GC-MS, GC-triple quadrupole mass spectrometer), Trapped Ion Mobility Spectrometry (TIMS), Magnetic Resonance Mass Spectrometry (MRMS), X-ray technologies, atomic force microscopy, fluorescence optical microscopy, infrared and Raman molecular spectroscopy, laboratory automation, software solutions (SCiLS Lab, MetaboScape, Biopharma Compass)

What Physicians Need to Know

Mass Spectrometry
Bruker Daltonics offers a wide array of innovative mass spectrometry solutions, including MALDI-TOF, ESI-TOF, ESI-quadrupole TOF (qTOF), UHR-TOF, FTMS, and ICP-MS systems. Their innovations include Trapped Ion Mobility Spectrometry (TIMS) for enhanced separation and sensitivity, smartbeam and scanning lasers for MALDI-MS Imaging with true pixel fidelity, and eXtreme Resolution FTMS (XR) technology for revealing Isotopic Fine Structure (IFS) signatures. Key products like the timsTOF series (Pro, fleX, Ultra 2) leverage PASEF® technology for rapid, sensitive, and high-throughput proteomics, lipidomics, and spatial multiomics. Bruker's MRMS technology (scimaX® and solariX series) provides exceptional resolution and mass accuracy for complex sample analysis and compound identification. They also offer solutions for targeted analytical testing and broader discovery research with outstanding dynamic range and MS/MS performance.
Analytical and Diagnostic Solutions
Bruker provides high-performance scientific instruments and analytical and diagnostic solutions that enable exploration of life and materials at molecular, cellular, and microscopic levels. Their offerings include integrated instrument and software tools for various applications, such as the TargetAnalysis™ software for multi-target compound screening in complex matrices, and MetaboScape® for metabolomics data evaluation and biomarker identification. They also specialize in solutions for clinical microbiology, including the MALDI Biotyper® for rapid and accurate identification of microorganisms.
Life Science Molecular Research
Bruker supports life science molecular research by providing tools for structural biology, proteomics, metabolomics, and spatial biology. Their solutions enable deeper insights into disease biology and drug discovery, with workflows for functional proteomics, proteoform analysis, and glycopeptide characterization. They offer advanced tools for single-cell analysis and multiomics, including spatial multiomics imaging for cancer research.
Applied and Pharma Applications
Bruker's solutions cater to applied and pharma markets, including drug discovery and development, with tools for high-throughput screening, protein analysis, and drug metabolism studies. They offer specialized equipment for forensic toxicology and doping control, providing rapid and reliable identification of drugs. Their technology also supports biopharma applications with software solutions like Biopharma Compass®.
Microscopy and Nanoanalysis
Bruker develops and manufactures a wide range of advanced optical, spectroscopic, and electron microscopy solutions for exploring life and materials at atomic, molecular, cellular, and microscopic scales. This includes infrared and Raman microscopy for micro chemical analysis of small traces and sensitive evidence.
Industrial Applications
Bruker's analytical tools are used in various industrial applications, including food safety, environmental monitoring, and industrial quality control. They provide solutions for rapid identification of materials, compositional analysis, and detection of contaminants in food and other products.
Cell Biology
Bruker offers solutions for cell biology research, including advanced imaging techniques to investigate the morphology and surface structure of cells and individual biomolecules at submolecular resolution.
Preclinical Imaging
Bruker provides preclinical imaging solutions for a broad spectrum of application fields, such as oncology, neurology, cardiology, inflammation, and infectious diseases. Their multimodal imaging approaches allow real-time visualization of cancer-related processes with high sensitivity and resolution.
Clinical Phenomics and Proteomics Research
Bruker is a leader in clinical phenomics and proteomics research, offering advanced workflows for deeper protein-sequence coverage, targeted validation, and proteoform analysis. Their timsTOF platforms, with PASEF® technology, are crucial for in-depth proteomics and phenomics studies, enabling the identification of biomarkers related to diseases.
Clinical Microbiology
Bruker supports clinical microbiology with rapid and accurate identification and analysis of microorganisms. Their MALDI Biotyper® platform uses proteomic fingerprints for molecular identification of bacteria, yeasts, and fungi, offering faster time-to-result compared to traditional methods. They also offer integrated NGS and molecular diagnostics workflows for deeper genomic characterization.
Spatial Biology and Single-Cell Analysis
Bruker provides cutting-edge solutions for spatial biology and single-cell analysis, including MALDI HiPLEX-IHC tissue imaging for multiplexed spatial proteomics and unbiased multiomic imaging for cancer research. Their CellScape™ instrument enables high-plex spatial imaging and quantification of protein biomarkers with single-cell and sub-cellular resolution.
Multiomics
Bruker is at the forefront of multiomics research, integrating different 'omics' data to provide a comprehensive understanding of biological systems. Their timsTOF fleX platform allows for spatial multiomics, combining protein mapping with unbiased small molecule imaging (lipids, glycans, metabolites) from the same tissue section.
Proteomics
Bruker offers advanced proteomics solutions, including the timsTOF Pro and timsTOF Ultra 2, which provide ultimate sensitivity, speed, and dynamic range for deep proteome analysis. They focus on functional proteomics, enabling researchers to move beyond canonical protein lists to understand biologically functional proteoforms and post-translational modifications (PTMs).
Metabolomics
Bruker's metabolomics solutions aim for comprehensive qualitative and quantitative analysis of small molecules to identify biomarkers related to diseases, drug toxicity, or environmental variations. Their MetaboScape® software, with the T-ReX algorithm, aids in identifying biomarkers in large sample cohorts and provides confident identification of known and unknown metabolites. They also offer specialized libraries like Bruker HMDB Metabolite Library and MetaboBASE® Plant Library for enhanced compound identification.
Lipidomics
Bruker provides advanced lipidomics workflows, including machine-learning based CCSPredict™ for reliable lipid identification and reduced reliance on retention time matching. Their 4D-Lipidomics workflows, utilizing TIMS technology and MetaboScape software, offer increased confidence in lipid identification by separating co-eluting isobaric lipids and providing accurate CCS values.
Infectious Disease Diagnostics
Bruker supports infectious disease diagnostics with rapid identification and analysis of microorganisms. Their MALDI Biotyper® platform is a key tool for clinical routine microbial identification, and they are developing rapid AST (Antimicrobial Susceptibility Testing) workflows for bloodstream infections and sepsis diagnostics.
Food Safety
Bruker offers analytical solutions to enhance food safety by enabling easier and faster detection of contaminants like toxins, bacteria, and other undesired materials in food products. They provide solutions for comprehensive chemical residue screening, targeted quantitation of pesticides, and food authenticity analysis.
Environmental Monitoring
Bruker's mass spectrometry systems are utilized in environmental monitoring for multi-target compound screening in complex matrices.
Forensics
Bruker provides analytical tools for forensic science, including illegal drug analysis, fiber and paint chip characterization, and gunshot residue analysis. Their solutions enable rapid and unambiguous characterization of forensic evidence, extracting maximum information from small samples. They also offer a benchtop FT-NMR solution for forensic narcotics testing.
Industrial Quality Control
Bruker's solutions contribute to industrial quality control by providing advanced analytical capabilities for various materials and products.
Drug Discovery
Bruker's technologies are instrumental in drug discovery, offering solutions for functional proteomics, proteoform analysis, and the investigation of drug targets. They provide tools for understanding disease biology and developing new applications that improve human life.
Physician Tip

For physicians, Bruker Daltonics' advanced mass spectrometry and analytical solutions offer significant advantages in diagnostics and research. Their clinical microbiology platforms, like the MALDI Biotyper®, enable rapid and accurate identification of microorganisms, which is crucial for timely and effective treatment of infectious diseases, including sepsis. The ongoing development of rapid Antimicrobial Susceptibility Testing (AST) workflows will further enhance clinical decision-making for critically ill patients. In clinical phenomics and proteomics, Bruker's high-resolution mass spectrometry systems provide deeper insights into disease mechanisms and potential biomarkers, moving beyond traditional protein analysis to functional proteoform characterization. This can lead to a better understanding of disease states and treatment responses. The spatial biology and multiomics capabilities allow for detailed analysis of tissue samples, providing a more complete picture of disease progression and therapeutic targets, particularly in cancer research. These technologies can aid in personalized medicine by offering comprehensive molecular profiling.

Bruker Daltonics emphasizes integrated instrument and software tools to enhance productivity and capabilities. Examples include the MetaboScape® software for metabolomics data processing and biomarker identification, and the TargetAnalysis™ software for multi-target compound screening. Their systems are designed to work with various separation technologies, including LC-MS and GC-MS. Bruker also collaborates with other companies, such as Evosep, to provide robust, high-throughput liquid chromatography systems that complement their mass spectrometry platforms. Furthermore, their clinical microbiology workflows are being integrated with next-generation sequencing (NGS) for a more comprehensive diagnostic pipeline.

Products by BRUKER DALTONICS

1 product in the directory

MALDI BIOTYPER CA (MBT-CA) SYSTEM
BRUKER DALTONICS
Lab & Diagnostics
The Bruker MALDI Biotyper CA System is an FDA-cleared in vitro diagnostic mass spectrometry system for rapid, accurate, and reliable identification of microorganisms from human specimens in clinical microbiology laboratories.
Contact vendor for pricing

What the Web Says

Bruker Daltonics is a leading provider of high-performance scientific instruments and analytical solutions, specializing in mass spectrometry and other technologies for life sciences, materials research, and industrial testing. Product reviews highlight impressive quality, efficient A/B testing capabilities, and user-friendly dashboards for certain products. However, some users note a learning curve and initial missing features that were later updated. Employer reviews indicate a mixed sentiment, with appreciation for talented personnel and opportunities for growth, but also concerns about management, limited upward mobility, and work-life balance.

Overall: Mixed

Strengths

  • Impressive product quality, meeting expectations in drug discovery.
  • Efficient A/B testing capabilities with rapid and intelligent experimentation.
  • Easy-to-use dashboard with smooth integrations and clear data visualizations.
  • Talented and committed employees who go the extra mile for customers.
  • Productive environment with opportunities for advancement and growth for some employees.
  • Relaxed workplace with generous vacation days for some roles.

Limitations

  • Higher cost compared to alternative products.
  • Slight learning curve and some non-intuitive functions in certain products.
  • Initial missing features in some products, though prompt updates are noted.
  • Patriarchal and confused management structure, with some senior management being disconnected from the business and customers.
  • Limited growth opportunities and upward mobility for employees.
  • Concerns about work-life balance, pay, and benefits in some reviews.

Based on reviews from: G2, Indeed, Biocompare, SelectScience, Reddit, Simply Hired

Last updated: 2026-11-01

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Press & Coverage

bruker.com
Bruker Spatial Biology Showcases High Fidelity Spatial Data and Integrated Multi-platform Workflows for Unprecedented Multiomic Insights at AACR 2026
Bruker Spatial Biology will present new cross-platform workflows and 208-plex datasets at AACR 2026, highlighting integrated spatial biology platforms for deeper insights into oncology and accelerated translational research. The company will showcase how its high-fidelity spatial platforms work together to reveal biological relationships not captured by single modalities.
2026-04
bruker.com
Bruker Advances Functional Proteomics with Novel timsUltra AIP and timsOmni Workflows for Drug Discovery & Development and Disease Biology Research
Bruker announced new timsUltra AIP and timsOmni workflows at the Human Proteome Organization World Congress 2026, designed for deeper protein-sequence coverage, targeted validation, and structural proteomics. These advancements aim to provide more comprehensive insights for drug discovery, development, and disease biology research.
2026-09
selectscience.net
Bruker highlights new technologies and latest innovations at AAPS 2026 PharmSci 360
Bruker showcased its latest analytical tools and software ecosystems at AAPS 2026 PharmSci 360, focusing on accelerating pharmaceutical research, drug development, and manufacturing. Key highlights included advancements in timsTOF platforms, integration with organ-on-a-chip technology, and updated process spectrometers.
2026-10
bruker.com
Bruker advances Functional Proteomics 2.0 with timsOmni™ mass spectrometry proteoform analysis for deeper insights into disease biology
Bruker announced advancements in Functional Proteomics 2.0 workflows on the timsOmni™ mass spectrometer, enabling researchers to analyze functional proteoforms and PTM-resolved peptide variants. New software releases in Bruker ProteoScape™, OmniScape™, and GlycoScape™ support advanced PTM discovery and glycoproteomics.
2026-02
nasdaq.com
Bruker Corporation Launches New timsMRMS System for Petroleomics, Sustainable Fuels and Advanced Energy Storage
Bruker launched the new timsMRMS system at ASMS, combining Trapped Ion Mobility Spectrometry (TIMS) with Magnetic Resonance Mass Spectrometry (MRMS) to analyze complex molecular structures in fossil fuels and green energy materials. This system offers unparalleled mass resolution and accuracy for confident molecular identification.
2026-06
fda.gov
510(k) Premarket Notification
A 510(k) Premarket Notification was filed by Bruker Daltonics GmbH & Co. KG, received on May 15, 2025, and a decision was made on August 13, 2025. The notification pertains to a product classified under code QBN.
2025-08
vanderbilt.edu
Spraggins awarded $4M NSF grant to develop next-generation molecular imaging platform
Jeff Spraggins of Vanderbilt was awarded a $4 million NSF grant to develop a next-generation molecular imaging platform, which will be a key resource at the Mass Spectrometry Research Center. This platform will be accessible to collaborators in academia, national labs, and industry.
unknown
nih.gov
Performance evaluation of a novel MBT LipidART module (Bruker Daltonics) for detection of colistin resistance in Escherichia coli and Klebsiella pneumoniae
A study evaluated the MBT LipidART module on a MALDI Biotyper® Sirius System from Bruker Daltonics for rapid detection of colistin resistance in E. coli and K. pneumoniae by analyzing lipid A profiles. The module showed high categorical agreement for E. coli but faced challenges with K. pneumoniae isolates.
2025-03

Frequently Asked Questions

Bruker Daltonics offers a variety of mass spectrometry systems, including MALDI-TOF, ESI-TOF, and UHR-TOF, which are designed for clinical diagnostics and research applications. Their solutions are used for diverse analytical problems in clinical proteomics, such as patient stratification, screening, monitoring disease progression, and predicting treatment response. Bruker's timsTOF platforms, for instance, are utilized in plasma proteomics research for biomarker discovery and personalized healthcare, enabling high-throughput analysis of proteins and post-translational modifications.
Bruker Daltonics provides a comprehensive analytical ecosystem for drug discovery, development, and manufacturing, utilizing mass spectrometry, NMR, and other techniques. Their solutions support various stages, including high-throughput screening for lead discovery, detailed studies of ADME-Toxicity, and lead optimization through investigation of protein-ligand interactions. The rapifleX® MALDI PharmaPulse, for example, offers high-throughput label-free mass spectrometry for large screening campaigns.
Bruker Daltonics is a significant contributor to multiomics research, offering solutions for proteomics, metabolomics, and lipidomics. Their timsTOF series, with Trapped Ion Mobility Spectrometry (TIMS) technology, enables 4D-Proteomics™, 4D-Multiomics, and SpatialOMx®, providing deeper insights into complex biological samples. For metabolomics and lipidomics, they offer solutions like MetaboScape® software and the timsMetabo platform for comprehensive analysis and identification of biomarkers.
Bruker Daltonics provides solutions for clinical microbiology and infectious disease diagnostics, including instrumentation for DNA extraction and PCR amplification for in vitro diagnostic applications. They have also collaborated on biosensor systems for identifying infectious organisms. Their technologies aim to streamline laboratory practices and enhance diagnostic capabilities, with products like FluoroType® and LiquidArray® for nucleic acid sequence detection.
Bruker Daltonics supports spatial biology and single-cell analysis with advanced platforms like the timsTOF fleX, which combines MALDI technology with spatial resolution for SpatialOMx®. They also offer the CellScape™ XR, a next-generation spatial proteomics platform designed for high-throughput, reproducible spatial proteomics in translational and clinical applications. The timsTOF SCP optimizes ion transfer for single-cell proteomics and immunopeptidomics.
Bruker Daltonics offers comprehensive support, including training courses and maintenance agreements, to ensure the reliability and productivity of their instruments. They engage in strategic partnerships and collaborations with research institutions and companies to advance diagnostic and research capabilities. Bruker also assists with grant writing efforts for SpatialOMx funding proposals, demonstrating their commitment to collaborative research.
Bruker Daltonics is committed to meeting strict regulatory data integrity standards, offering updated compliance and automation software pipelines. Their solutions are designed to provide high accuracy, efficiency, and reliability, which are crucial for regulatory compliance in clinical and pharmaceutical settings. While many products are for research use only, their focus on robust and accurate data is essential for eventual clinical translation.

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