Products

AI100
SigTuple Technologies Pvt.
Lab & Diagnostics
SigTuple AI100 is an AI-powered in-vitro diagnostic device that automates the microscopic analysis of blood and urine samples, enhancing diagnostic accuracy and efficiency for pathology labs and hospitals.

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About SigTuple Technologies Pvt.

SigTuple Technologies Pvt. Ltd. is a pioneering healthtech company that leverages artificial intelligence (AI), robotics, and cloud technology to revolutionize medical diagnostics, aiming to make healthcare more accurate, accessible, and affordable. The company’s core innovation lies in automating and enhancing traditional pathology lab processes, particularly the manual microscopic review of biological samples.

Their flagship product, AI100, is an AI-powered digital microscope and analyzer designed for the automated analysis of visual medical data from samples such as blood, urine, and semen. This system captures high-quality microscopic images and uses proprietary AI models to analyze them, streamlining diagnostic workflows, improving reliability, and significantly reducing the time required for analysis. The AI100 system can pre-classify cells and generate reports within minutes, aiding in the detection of various health conditions including blood cancers, infections, inflammations, different types of anemia, and viral infections.

SigTuple’s solutions are designed for seamless integration into existing systems within hospitals, diagnostic centers, and other healthcare providers. Beyond pathology, the company also extends its AI platform to ophthalmology for analyzing retinal images to detect conditions like diabetic retinopathy, glaucoma, and age-related macular degeneration (AMD). By providing real-time insights and enabling AI-assisted remote diagnostics, SigTuple empowers medical professionals and contributes to better patient outcomes globally.

Focus Areas

AI-powered diagnostic solutions digital microscopy pathology hematology urine analysis robotics cloud computing data science medical diagnosis

Business Intelligence

Key InvestorsAccel, Endiya Partners, Trusted Insight, SIDBI Venture Capital, Chiratae Ventures, Venture Highway, Pi Ventures, Sachin Bansal, Binny Bansal, IDG Capital, Trifecta Capital, NetApp Excellerator, Axilor Ventures
PartnershipsKrsnaa Diagnostics, HCG Hospitals, Thyrocare Technologies, Molbio Diagnostics, HORIBA Medical
TechnologyAI100 (AI-powered digital microscope), Shonit (blood analyzer), Shrava (urine analyzer), Manthana (continuous learning AI platform), robotics, cloud-based platform
FDA Clearances1 cleared products (estimated)

What Physicians Need to Know

AI-powered Diagnostic Solutions
SigTuple specializes in AI-driven solutions for the healthcare industry, transforming diagnostic and monitoring processes. Their primary innovation involves automating pathology labs and blood testing procedures using artificial intelligence to analyze medical images and data, aiming to automate the manual review of visual medical data.
Digital Microscopy & Pathology Automation
Their flagship product, AI100, is an automated digital microscope that converts physical samples into microscopic digital images. This is coupled with AI-powered software that analyzes these digital images to generate reports for review by pathologists.
Hematology & Urine Analysis
SigTuple's solutions specifically automate the microscopic analysis of blood smears (Shonitu2122) and urine samples (Shravau2122). These systems can detect various health issues, including blood cancer, infections, inflammations, different kinds of anemia, viral infections like Dengue, hemoparasite affections like malaria, and urinary tract infections.
Robotics Integration
The company combines AI, robotics, and data science to build smart healthcare screening solutions. The AI100 automated digital microscope utilizes a robotic arm to precisely position samples for high-quality image capture.
Cloud Computing & Data Science
SigTuple leverages cloud-based analysis and data science extensively. Their AI-powered software modules on the cloud utilize digitized slides to generate comprehensive reports, and their core 'Manthana' platform is a continuous learning AI platform for healthcare that churns data to generate intelligence.
Enhanced Medical Diagnosis
Their core mission is to dramatically improve diagnostic accuracy, speed, and efficiency, reducing human error and improving patient outcomes. They provide detailed clinical insights to pathologists, accessible via a standard web browser.
Physician Tip

For physicians, SigTuple's AI-powered solutions offer significant advantages. Embrace the AI-assisted diagnostics to streamline routine tasks, allowing you to dedicate more time to complex cases and critical decision-making. Leverage the remote review capabilities of platforms like AI100 to provide expert opinions and manage workload efficiently, overcoming geographical barriers. The system's ability to detect rarer abnormalities more effectively than manual methods can lead to earlier and more accurate diagnoses. Utilize the visual evidence provided alongside AI-generated reports for verification, enhancing confidence in your diagnoses and improving patient outcomes through faster turnaround times and reduced human error.

SigTuple's solutions, including the AI100 platform, are designed for seamless integration into existing systems within hospitals, diagnostic centers, and healthcare providers to enhance diagnostic workflows. They are deployed in major laboratory and hospital chains. The company typically charges an upfront cost for the hardware and a recurring charge for the usage of the software, facilitating a comprehensive and integrated diagnostic ecosystem.

Products by SigTuple Technologies Pvt.

1 product in the directory

AI100
SigTuple Technologies Pvt.
Lab & Diagnostics
SigTuple AI100 is an AI-powered in-vitro diagnostic device that automates the microscopic analysis of blood and urine samples, enhancing diagnostic accuracy and efficiency for pathology labs and hospitals.

What the Web Says

SigTuple Technologies Pvt. receives mixed reviews, with some users praising its AI-driven healthcare solutions for efficiency and accuracy, particularly in pathology and ophthalmology. However, others express concerns about product maturity, customer support responsiveness, and internal company culture, citing high workload and management issues.

Overall: Mixed

Strengths

  • AI-powered diagnostics improve efficiency and accuracy in pathology and ophthalmology.
  • Potential to reduce manual errors and improve diagnostic turnaround time.
  • Innovative technology with a focus on healthcare automation.
  • Some employees appreciate the learning opportunities and challenging work.
  • Solutions can be beneficial for remote diagnostics and underserved areas.
  • Positive impact on reducing healthcare costs through automation.

Limitations

  • Product maturity and stability issues reported by some users.
  • Customer support responsiveness and effectiveness can be inconsistent.
  • High workload and demanding work environment reported by some employees.
  • Concerns about management style and internal communication.
  • Integration challenges with existing healthcare IT systems.
  • Some users found the user interface to be less intuitive or requiring a learning curve.

Based on reviews from: G2, Glassdoor, Capterra, Reddit, Healthcare IT Reviewers (general)

Last updated: 2026-07-20

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Press & Coverage

CXOtoday
SigTuple Launches AS76, an Edge-AI Digital Morphology Analyzer for Peripheral Blood Smear Review Powered by NVIDIA
SigTuple launched AS76, an Edge-AI Digital Morphology Analyzer for peripheral blood smear review, powered by NVIDIA, in February 2026.
2026-02
The Economic Times
Medtech startup SigTuple raises $4 million from Sidbi Venture Capital, others
SigTuple raised $4 million in an extended Series C funding round led by Sidbi Venture Capital in August 2024, with participation from existing investors.
2024-08
Express Healthcare
AI100 with Shonit by SigTuple receives USFDA 510(k) clearance
SigTuple's AI100 with Shonit, a peripheral blood smear application, received U.S. FDA 510(k) clearance in September 2023, making it the first integrated hardware and AI medical device from India to achieve this.
2023-09
PMC - NIH (Cureus Journal of Medical Science)
Transformative Role of Artificial Intelligence in Reporting Haematology Cases
A study published in November 2024 explores the use of SigTuple's AI100 automated machine for microscopic analysis of peripheral blood smears, demonstrating its efficiency in cell identification and accelerating diagnostic turnaround times.
2024-11
Entrepreneur India
SigTuple Raises INR 34.5 Crore Fresh Round Of Funding
SigTuple secured INR 34.5 crore in a funding round in March 2023, led by existing investors Endiya Partners and Accel, to drive geographical expansion, product portfolio expansion, and regulatory clearances.
2023-03
NITI Aayog
AI-Enabled Diagnostics: SigTuple's Breakthrough in Indian Pathology
This article from July 2025 highlights how SigTuple's AI-powered diagnostic device, AI100, is revolutionizing pathology in India by addressing the shortage of pathologists and improving diagnostic speed and accuracy.
2025-07
IJIRMS (International Journal of Innovative Research in Medical Science)
Evaluation of Automated Blood Microscopy System AI100 with Shonit in a Tertiary Care Center in Northern India
A publication in 2024 details the evaluation of SigTuple's Automated Blood Microscopy System AI100 with Shonit in a tertiary care center in Northern India.
2024
VCCircle
Med-tech startup SigTuple gets new investor in Series C round
SigTuple raised $16 million in a Series C funding round in April 2019, led by Trusted Insight, with participation from existing investors and Flipkart co-founder Binny Bansal.
2019-04

Frequently Asked Questions

SigTuple's flagship product is the AI100, an automated digital microscope that digitizes biological samples like blood and urine. This hardware is complemented by AI-powered software, specifically Shonitu2122 for peripheral blood smear analysis in hematology and Shravau2122 for urine analysis, which classify cells and flag abnormalities on a cloud-based platform called Manthana.
SigTuple's AI algorithms are trained on extensive datasets, including over 25,000 pathology slides, and have undergone more than eight clinical trials analyzing over 15,000 samples. The system provides clinical insights backed by visual evidence, allowing pathologists to review and, if necessary, modify AI classifications, thereby enhancing accuracy and reducing human error and fatigue.
SigTuple's AI100 device, along with its Shonitu2122 and Shravau2122 applications, is CE certified. Notably, the AI100 with Shonitu2122 received US FDA 510(k) clearance in 2023, marking it as the first integrated hardware and AI medical device from India to achieve this. The company also ensures compliance with data privacy regulations such as GDPR and HIPAA by not requiring personally identifiable patient information.
SigTuple often offers its smart microscope at very affordable prices or even for free to some labs, charging a cloud service fee on a pay-per-diagnosis basis for the AI analysis. They also provide free access to their Manthana platform in exchange for anonymized data, aiming to make advanced diagnostics more accessible and affordable.
SigTuple provides 24/7 customer support and proactive technical assistance, with most issues handled remotely. Their maintenance plan includes predictive maintenance to anticipate device failures, annual preventive maintenance, and corrective maintenance with a service engineer dispatched within six hours for complaints.
SigTuple has partnered with numerous hospitals and laboratory chains for data collection and clinical trials, and has a distribution partnership with HORIBA Medical for the Indian subcontinent. They are also collaborating with Molbio Diagnostics to develop AI-powered, portable point-of-care diagnostic devices, expanding their reach and decentralizing testing.
Founded in 2015, SigTuple has demonstrated strong financial stability, raising over $40 million in funding from investors like Accel, Endiya Partners, and SIDBI Venture Capital, with the latest round in August 2024. Their long-term vision is to democratize quality healthcare by expanding their product portfolio, including a next-generation product (AS76) and point-of-care solutions, and driving geographical expansion into Europe and the Americas.
While currently focused on hematology (Shonitu2122) and urine analysis (Shravau2122), SigTuple is actively working on expanding its AI capabilities to other tests on the same platform, including a universal scanner and histopathology applications. They are also developing point-of-care devices using microfluidics for essential tests in hematology, biochemistry, and electrochemistry, aiming to bring diagnostics closer to patients.

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