Products

Massive Bio
Massive Bio
Patient Engagement & Education
Massive Bio is an AI-powered precision oncology platform connecting cancer patients with clinical trials and drug matching based on their medical profiles and genomics, streamlining access to advanced treatments globally.

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About Massive Bio

Massive Bio is a digital health company that leverages artificial intelligence (AI) to revolutionize oncology clinical trial matching and patient access to advanced cancer treatments. Their mission is to ensure every cancer patient can access clinical trials, irrespective of their geographical location or financial status. The company’s proprietary AI platform, including tools like SYNERGY-AI and Deep Learning Clinical Trial Matching System (DLCTMS), meticulously analyzes comprehensive patient data—such as diagnosis, disease stage, genomic profiles, biomarkers, and treatment history. This enables precise matching of patients to a vast global database of actively recruiting clinical trials, which can exceed 19,000 studies.

For physicians, Massive Bio offers an invaluable resource to streamline the complex process of clinical trial referrals. Their “Trial Relay” platform is designed to save physicians time and enhance patient outcomes by providing AI-powered matching capabilities. Crucially, all AI-generated matches undergo validation by Massive Bio’s team of physicians, ensuring a blend of technological innovation with expert clinical oversight. The company fosters extensive collaborations with leading pharmaceutical companies, global partners, and patient advocacy groups, operating in numerous countries and languages to broaden the reach of advanced cancer clinical trials. Beyond matching, Massive Bio provides comprehensive concierge services, guiding patients through eligibility assessments, financial considerations, and appointment scheduling, thereby alleviating significant burdens on both patients and their treating oncologists.

Focus Areas

AI-driven oncology clinical trial matching precision medicine real-world data patient identification pre-screening concierge enrollment drug matching oncology data solutions

Business Intelligence

Key InvestorsRevo Capital, Cavendish Impact Foundation (CIF), DEG – Deutsche Investitions- und Entwicklungsgesellschaft mbH, Kenan Turnacıoğlu PaigeAI, Schusterman Family Investments, International Finance (Washington D.C.)
PartnershipsTheSocialMedwork, Flatiron Health, American Cancer Society (ACS ACTS), Foundation Medicine, Un Ensayo Para Mi (UEPM), Precision Cancer Consortium (PCC)
TechnologySYNERGY-AI/DLCTMS (Deep Learning Clinical Trial Matching System), Natural Language Processing (NLP), Computer Vision, Large Language Model (LLM) and Generative Pre-trained Text (GPT) for Dr Arturo AI (for physicians) and Ask Fiona AI (for patients), Reticulum Nexus (multi-agent platform)

What Physicians Need to Know

AI-driven Oncology Clinical Trial Matching
Massive Bio's core offering is its AI-powered platform (SYNERGY-AI, Trial Relay, Patient Connect) that rapidly and accurately matches cancer patients to suitable clinical trials based on their diagnosis, genomic profile, and geographic location. This significantly reduces the time and effort traditionally required for trial identification.
Precision Medicine & Drug Matching
They specialize in tailoring cancer treatments by leveraging genomic and molecular profiles, integrating precision medicine, targeted therapies, immunotherapy options, and clinical trials. Their AI-powered drug matching product helps oncologists identify comprehensive treatment options, including recently approved drugs and active clinical trials.
Real-World Data (RWD) & Oncology Data Solutions
As an AI-enabled real-world data company, Massive Bio utilizes proprietary data assets including parameterized cancer patient data, an Ontology DB (a comprehensive knowledge base of cancer terminology, drugs, and biomarkers), and a Command Center for advanced data analytics. They offer solutions like Trial Vision and Drug Utilization Optimizer (DUO).
Patient Identification, Pre-screening & Concierge Enrollment
Massive Bio streamlines the entire patient journey by identifying and virtually pre-screening patients for clinical trials. They provide comprehensive concierge services, including patient relations coordinators and oncology nurses, to guide patients through the enrollment process, from initial inquiry to post-enrollment.
Global Reach & Accessibility
Operating in 18 countries and supporting 11 languages, Massive Bio collaborates with 17 top pharmaceutical companies, 130+ global partners, and 400+ patient advocacy groups to expand access to advanced cancer clinical trials worldwide.
Physician Tip

Massive Bio's platform, particularly 'Trial Relay' and 'Dr. Arturo AI,' is designed to significantly reduce the administrative burden of finding and referring patients to clinical trials. Physicians can securely submit patient information online, receive AI-generated clinical summaries and tailored trial matches, and even identify trials recruiting at their own institution. The integrated concierge services for patients further free up physician time, ensuring patients receive comprehensive support throughout their trial journey. Leveraging their real-world data and AI-driven insights can also aid in more informed, data-driven treatment decisions and provide access to the latest therapeutic options. The platform is HIPAA-compliant, ensuring patient data privacy.

Massive Bio's SYNERGY-AI platform is built to function as clinical infrastructure, embedded within oncology workflows. It processes information from electronic health records (EHRs) and integrates with various stakeholders in the pharmaceutical value chain, including drug developers, hospitals, and genomic companies. They also partner with health tech companies like Flatiron Health to enhance patient identification and leverage robust data harmonization frameworks with partners like Prognos Health for enhanced real-world data and insights. The system is designed for real-time, actionable intervention at the point of care.

Products by Massive Bio

1 product in the directory

Massive Bio
Massive Bio
Patient Engagement & Education
Massive Bio is an AI-powered precision oncology platform connecting cancer patients with clinical trials and drug matching based on their medical profiles and genomics, streamlining access to advanced treatments globally.

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Press & Coverage

BioSpace
Massive Bio Partners with TOUCH, The Black Breast Cancer Alliance and Navigating Trials to Expand Cancer Patients' Access to Clinical Trials
Massive Bio announced a partnership with TOUCH, The Black Breast Cancer Alliance, and Navigating Trials to integrate its AI-powered trial matching directly into their platforms, aiming to provide seamless, no-cost access to personalized clinical trial options for cancer patients.
2026-06
Clinical Trials Arena
Massive Bio and FOMAT collaborate for oncology clinical trials
Massive Bio partnered with FOMAT to pilot AI-based prescreening for oncology clinical trials across a community-focused research network in the US, aiming to identify eligible patients earlier and reduce friction in trial enrollment.
2026-07
Business Wire
Massive Bio Announces Partnership with Sequence Me Now to Help Cancer Patients Access Clinical Trials
Massive Bio announced a new partnership with Sequence Me Now (SMN), a nonprofit patient advocacy organization, to connect patients using SMN's self-advocacy resources with Massive Bio's AI-powered clinical trial matching.
2026-07
Business Wire
Massive Bio Expands Global Access to Clinical Trials Through AI-Powered Parameterization and Pre-Screening with OpenAI
Massive Bio announced a collaboration with OpenAI to enhance clinical trial accessibility through large-scale parameterization of clinical trial protocols and real-time patient pre-screening capabilities.
2026-04
Massive Bio
Massive Bio Publishes Landmark AI Clinical Trial Matching Study in ESMO Journal
Massive Bio announced the publication of a peer-reviewed prospective study in ESMO Real World Data and Digital Oncology, demonstrating its AI platform can match cancer patients to clinical trials four times faster than conventional methods.
2026-04
Massive Bio
Massive Bio Receives CNIL Certification for GDPR Compliance
Massive Bio received certification from the French Data Protection Authority (CNIL), confirming its compliance with GDPR and French data privacy laws, allowing it to securely process patient medical records in France.
2025-04
Business Wire
Massive Bio Recognized by White House Cancer Moonshot, Launches $15 Million Initiative at JPM 2025
Massive Bio was recognized by the White House Cancer Moonshot and launched a $15 million initiative to fund its AI-driven clinical trial matching platform and pre-screening hubs, aiming to serve over 50,000 unique cancer patients annually.
2025-01
Massive Bio
Massive Bio Raises $9 Million To Scale Growth and Fuel Global Expansion of AI-Enabled Oncology Clinical Trial Platform
Massive Bio raised $9 million in funding to scale its global operations, invest in marketing, and launch new oncology clinical trial enrollment products with its data-rich platform.
2022-06

Frequently Asked Questions

Massive Bio's AI platform, including Trial Relay, rapidly and accurately matches cancer patients to suitable clinical trials by analyzing their medical records, genomic profiles, and biomarker data. This streamlines the referral process, saving physicians time and expanding access to advanced treatment options for their patients.
Massive Bio leverages AI and integrates genomic and molecular testing results to enable precision oncology, tailoring treatment plans and trial matching to each patient's unique profile. The company also utilizes proprietary real-world data (RWD) assets and partners with organizations like Prognos Health to generate actionable insights, optimizing clinical trials and patient journeys.
Massive Bio's platform identifies and pre-screens patients by evaluating their medical history against complex trial eligibility criteria, significantly reducing the operational burden on sites. They offer comprehensive concierge services, including support from patient relations coordinators and oncology nurses, to guide patients and physicians through the entire clinical trial enrollment process.
Massive Bio offers the Synergy AI Platform, which includes solutions like Trial Relay for physician referrals, Patient Connect for patient engagement, and Pre-Screen Plus for clinical operations. They also provide Dr. Arturo AI as a co-pilot for physicians to interactively summarize patient data and identify matching trials.
Massive Bio is committed to stringent data privacy and regulatory compliance, adhering to standards such as HIPAA, GDPR, and maintaining SOC 2 certification. They employ de-identification processes for clinical summaries and obtain explicit patient consent for data processing, ensuring confidentiality and secure handling of sensitive medical records.
While Massive Bio offers free trial matching services to patients, their engagement model for healthcare providers and administrators typically involves partnerships to integrate their AI-driven solutions into existing workflows. They provide support through dedicated physician networks, roundtables for professional exchange, and concierge services that ease the enrollment burden for both patients and clinical staff.
Founded in 2015, Massive Bio has demonstrated significant growth and stability, securing over $23 million in funding and expanding its operations globally across 17 countries. They have extensive partnerships with over two dozen pharmaceutical companies, CROs, hospital networks like The Oncology Institute, and organizations such as the Precision Cancer Consortium and the American Cancer Society.

Investors

Who's funded Massive Bio.

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