Products

BrainSee
Darmiyan
Neurology AI
BrainSee by Darmiyan is an FDA-approved, AI-driven software platform that utilizes MRI data and cognitive test scores to predict the likelihood of progression from amnestic mild cognitive impairment (aMCI) to Alzheimer's dementia within five years.

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About Darmiyan

Darmiyan is a pioneering healthcare AI company focused on revolutionizing brain health management through advanced imaging technology. Their core mission is to provide early detection, visualization, and quantification of neurodegenerative disorders, with a primary focus on Alzheimer’s disease.

Their flagship product, BrainSee, is an FDA-approved, AI-powered clinical test designed for physicians. It utilizes advanced AI algorithms to analyze routine clinical brain MRIs and cognitive test results, generating a numerical score that predicts the likelihood of progression from amnestic mild cognitive impairment (aMCI) to Alzheimer’s dementia within five years. This non-invasive tool aims to empower healthcare providers with precise, personalized patient care by enabling timely interventions, guiding preventive strategies, and potentially delaying the onset of dementia, thereby improving patient outcomes. The technology is built upon over four decades of cutting-edge neuroscience research combined with sophisticated medical image processing and machine learning techniques.

What Physicians Need to Know

Specialization
Darmiyan specializes in the early detection and prognosis of Alzheimer's disease using AI-powered analysis of standard brain MRI scans. Their flagship product, BrainSee, predicts the likelihood of progression from amnestic Mild Cognitive Impairment (aMCI) to Alzheimer's dementia within five years.
Key Differentiators
Darmiyan stands out by offering a non-invasive, highly accurate, and reliable prognostic tool that utilizes widely available clinical brain MRIs. Unlike traditional biomarker-based tests, BrainSee focuses on quantifying cellular-level changes in brain tissue architecture to predict disease progression with 91% accuracy. It can detect Alzheimer's up to fifteen years before symptoms appear in cognitively normal individuals.
Technology Stack
Their core technology, DarmiScope (a 'virtual microscope' of the human brain), leverages advanced medical AI and machine learning algorithms to resolve tissue structure in every voxel of a brain MRI. This neuroscience-powered AI runs on a highly scalable, fully automated cloud-based software platform, ensuring secure and HIPAA-compliant access.
FDA Approval
BrainSee received FDA De Novo approval in January 2024, making it the first prognostic test to predict the likelihood of progression to Alzheimer's dementia. It also received FDA Breakthrough Device designation in 2021.
Physician Tip

For physicians, Darmiyan's BrainSee offers actionable insights by providing an objective, patient-specific score (0-100%) that indicates the 5-year risk of progression to Alzheimer's dementia. This enables timely and personalized interventions, potentially delaying dementia onset and improving patient outcomes. The non-invasive nature and use of standard MRI scans mean it can be easily integrated into routine clinical workflows, and any licensed physician, including primary care providers, can prescribe the test. It helps in reassuring lower-risk patients, reducing the need for costly and invasive tests, and can be used to monitor the effectiveness of treatments and lifestyle modifications over time. Furthermore, BrainSee aids in selecting optimal candidates for clinical trials, advancing drug development for Alzheimer's.

Darmiyan's BrainSee platform is designed for seamless integration into existing clinical workflows. It combines standard clinical brain MRI data with cognitive assessments and is accessible to physicians via a secure and HIPAA-compliant web portal.

Products by Darmiyan

1 product in the directory

BrainSee
Darmiyan
Neurology AI
BrainSee by Darmiyan is an FDA-approved, AI-driven software platform that utilizes MRI data and cognitive test scores to predict the likelihood of progression from amnestic mild cognitive impairment (aMCI) to Alzheimer's dementia within five years.

What the Web Says

Darmiyan is a company focused on brain health innovation, particularly in detecting neurodegenerative diseases like Alzheimer's at early stages. Their flagship product, BrainSee, is an AI-powered software that uses MRI brain scans and cognitive assessments to predict the likelihood of progression from mild cognitive impairment (MCI) to Alzheimer's dementia within five years. The company has received FDA De Novo approval for BrainSee, highlighting its potential as a non-invasive and accurate prognostic tool. Employer reviews are limited but generally positive, citing a supportive environment and passionate team.

Overall: Positive

Strengths

  • BrainSee offers prognostic accuracy for Alzheimer's disease.
  • BrainSee is a non-invasive diagnostic tool.
  • BrainSee provides same-day test results.
  • BrainSee integrates seamlessly into clinical workflows.
  • Supportive management and flexible schedule reported by employees.
  • Small, tight-knit, and passionate team environment.

Limitations

  • Limited public employee reviews available.
  • No specific product cons found in the provided search results.
  • No specific company/employer cons found in the provided search results beyond the limited number of reviews.
  • No reviews from G2, Glassdoor, Capterra, or Reddit were found for Darmiyan, only for similarly named companies or general review platforms.

Based on reviews from: Indeed.com, Darmiyan Website, Notebookcheck, MedTech Dive, BioSpace, Global Data

Last updated: 2026-07-18

Videos

News, demos, and interviews about Darmiyan.

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Press & Coverage

PR Newswire
Darmiyan Receives FDA Approval for BrainSee, the First Prognostic Test for Predicting Likelihood of Progression to Alzheimer's Dementia
Darmiyan announced FDA approval for BrainSee, a first-in-class clinical test that non-invasively predicts the progression to Alzheimer's disease, marking a significant advancement in brain health and disease management.
2024-01
PR Newswire
Darmiyan Receives FDA Approval for Post-Market Surveillance Study of BrainSee, the First-in-Class Clinical Test for Predicting Risk of Progression to Clinical Alzheimer's Disease
Darmiyan received FDA approval for a 7-year post-market surveillance study for BrainSee, aiming to further validate its safety and effectiveness in a diverse patient population across the United States.
2025-05
BioSpace
Darmiyan, Inc. Announces Launch of Groundbreaking BrainSee Platform for Alzheimer's Testing
Darmiyan launched its BrainSee Platform, integrating the FDA-approved BrainSee Test for Alzheimer's disease, designed to revolutionize how individuals assess and monitor their risk of progression to Alzheimer's dementia.
2024-09
MedTech Dive
Imvaria and Darmiyan receive FDA authorizations for AI-enabled diagnostic tools
The FDA granted De Novo authorization to Darmiyan's BrainSee, an AI-powered software that uses MRI scans and cognitive tests to predict the likelihood of progression from mild cognitive impairment to Alzheimer's dementia within five years.
2024-01
BioSpace
Global Pharma Giant Eisai Leads a $6M Series Seed Investment Round in Darmiyan to Expedite its Clinical Market Entry
Pharma giant Eisai led a $6 million Series Seed investment round in Darmiyan, aiming to accelerate the clinical market entry of Darmiyan's advanced brain diagnostics.
2020-04
MCRA
MCRA Supports Darmiyan with FDA Approval for BrainSee Device
MCRA supported Darmiyan in achieving FDA Breakthrough Device Designation in 2021 and subsequently securing De Novo marketing authorization for BrainSee in January 2024, a significant step for Alzheimer's diagnostics.
2024-05
Darmiyan (Scientific Publications)
Early Detection of Alzheimer's Disease with BrainSee, the FDA Breakthrough Software Medical Device (CTAD 2021 press release)
This publication highlights BrainSee as an FDA Breakthrough Software Medical Device for the early detection of Alzheimer's Disease, presented at the CTAD 2021 conference.
2021-11
PR Newswire
The first Virtual Microscope of the human brain, developed by Darmiyan, accurately measures Alzheimer's-related abnormalities
Darmiyan announced the successful third-party validation of its BrainSee technology, a virtual microscope for the human brain, which accurately measures Alzheimer's-related abnormalities and predicts cognitive future in MCI patients.
2020-08

Frequently Asked Questions

Darmiyan's flagship product is BrainSee, an FDA-authorized, AI-powered clinical tool designed to help physicians predict the likelihood of Alzheimer's disease progression in patients over 55 with amnestic mild cognitive impairment (aMCI) within five years. It integrates standard brain MRI, basic cognitive testing, age, and sex to generate a personalized prognostic score. Darmiyan also mentions DarmiSpace, a personalized lifestyle management platform that uses BrainSee scores to guide interventions for delaying or preventing cognitive decline.
Darmiyan's BrainSee received FDA marketing authorization in January 2024 through the De Novo pathway, making it the first and only non-invasive prognostic tool of its kind for clinical use. It also received FDA Breakthrough Device Designation in 2021. The company has secured FDA approval for a 7-year post-market surveillance study to further validate BrainSee's safety, effectiveness, and real-world utility.
BrainSee is designed for accessibility, allowing any licensed physician, including general practitioners, geriatricians, psychiatrists, and preventive medicine specialists, to order it. Physicians upload a patient's MRI scan files and cognitive test scores to a secure, HIPAA-compliant web portal, which then renders an Alzheimer's dementia probability score on the same day. While specific support details aren't publicly detailed, the company provides a tutorial and interpretation guide for physicians, as well as a guide for patients and caregivers.
Specific pricing details for Darmiyan's products are not publicly disclosed. Healthcare AI solutions often utilize various strategic pricing models, such as value-based, subscription, or per-test fees, to align with clinical adoption and economic incentives. Interested healthcare providers and administrators would need to contact Darmiyan directly for detailed pricing and implementation costs.
Darmiyan has established significant partnerships, including a $6M seed investment round led by pharmaceutical giant Eisai. They collaborate with leading institutions like the National Alzheimer's Coordinating Center (NACC), UC Davis, and UAB Alzheimer's Disease Research Centers for studies. Additionally, Darmiyan is partnering with the Five Star Home Health Care consortium for the Medicare GUIDE program and has been selected as a Preferred Provider for Cognitive Health Solutions by the California Association of Health Facilities (CAHF).
Founded in San Francisco in 2016 and backed by Y-Combinator, Darmiyan has demonstrated ongoing financial activity and growth. The company successfully closed a $6 million seed investment round in 2020, led by Eisai, with participation from IT-Farm and Y-Combinator. In late 2023, Darmiyan also filed a notice of an exempt offering to raise over $3.5 million in new equity investment, indicating continued funding and expansion efforts.

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