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Augmentiqs Augmented Reality Microscope (ARM)

by Augmentiqs Medical Ltd. · Based in Israel → — Digital pathology... inside your microscope

Dermatology Oncology Pathology

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Overview

Augmentiqs Augmented Reality Microscope (ARM) integrates augmented reality into existing microscopes, providing real-time access to digital pathology software, AI algorithms, and telepathology capabilities directly within the microscope’s field of view. This system transforms traditional light microscopes into smart, connected devices, enabling pathologists to work more effectively, connect remotely with colleagues, and conduct groundbreaking medical research. By operating from within the existing microscope, Augmentiqs eliminates the need to first digitize slides to access digital tools, offering a cost-effective solution for labs transitioning to digital pathology.

The Augmentiqs platform is designed with an Open API, allowing for multi-directional communication and integration with various digital systems and software, including electronic medical/health record (EMR/EHR) systems, image sharing, data management systems, and other software plugins. It supports the deployment of any digital pathology software algorithm, including popular tools like ImageJ, QuPath, Mindpeak, and AIRA Matrix. The system captures a live, high-resolution view of the region of interest, displaying digital information as augmented reality within the microscope eyepiece. This allows pathologists to interact with the specimen, perform measurements, annotate, count cells, and run AI algorithms without lifting their eyes from the microscope.

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Key Features

Augmented Reality Microscopy (ARM) for existing microscopes
Real-time access to digital pathology software
Integration of AI algorithms directly in the field of view
Real-time telepathology for remote consultations and collaboration
Microscope stage tracking for research and automation
Manual slide scanning directly from the microscope
Open API for integration with third-party software and algorithms
High-resolution image capture and annotation tools
LIS integration for real-time data transfer
Cost-effective alternative to whole slide imaging

Use Cases

Real-time telepathology for frozen sections, tumor boards, and peer review
Computer-assisted diagnostics and quantitative image analysis (e.g., Ki-67, cell counting, color segmentation)
AI training and deployment for pathology artificial intelligence developers
Pathology education and live collaboration between remote locations
Automated data collection and audit of microscope workflow
Research and preclinical studies in pathology

What Physicians Need to Know

Evidence Base

Augmentiqs ARM has been the subject of a pivotal study published in the Journal of Cancer Cytopathology, titled u201cKi-67 Proliferation Index in Neuroendocrine Tumors: Can Augmented Reality Microscopy With Image Analysis Improve Scoring?u201d. This peer-reviewed study demonstrated how Augmentiqs ARM can improve clinical diagnosis using computer-assisted diagnostics. The technology is also used in preclinical studies, including the world's first preclinical deployment of deep-learning algorithms in an augmented reality microscope for fatty liver and myopathy tissue samples. Augmentiqs is also being used to conduct groundbreaking medical and pathology research.

Clinical Validation Studies

A pivotal study conducted by Dr. Liron Pantanowitz at the University of Pittsburgh Medical Center (UPMC) demonstrated that Augmentiqs ARM can improve clinical diagnosis, reduce costs compared to alternative digital pathology technologies, and save considerable time in quantitative scoring. This study, published in the May 2020 Journal of Cancer Cytopathology, specifically explored the functionality, accuracy, and time-saving advantages of Augmentiqs for Ki-67 neuroendocrine tumor scoring. Another study, published in May 2025, investigated the utility and trustworthiness of a Gastric PD-L1 CPS AI Model using an ARM-AI system with 12 expert pathologists.

Alert Fatigue Management

The augmented reality overlay can be easily turned off when toolsets are not required, suggesting a mechanism to manage potential alert fatigue by allowing pathologists to control when they view additional digital information.

Differential Diagnosis Support

Augmentiqs ARM enables the real-time deployment of AI algorithms and other digital pathology applications directly within the microscope, which can include computer-assisted diagnosis and advanced cell analysis. This allows for the overlay of morphometric tools, advanced cell analysis, and critical case data onto the microscope's field of view, supporting pathologists in their diagnostic process.

Clinical Workflow Integration

Augmentiqs ARM integrates seamlessly into existing infinity-corrected light microscopes, adding a digital overlay without degrading the optical quality or changing the regular function of the microscope. This minimizes disruption to routine workflow in busy pathology practices. It eliminates the need for time-consuming and expensive slide scanning, allowing pathologists to access digital tools and AI directly from the live view of the glass slide. The system also supports real-time telepathology for remote consultations, peer review, and frozen sections, enabling multi-directional annotations and AI integration directly on the image.

Decision Audit Trail

Augmentiqs allows for the saving of images with overlayed data, annotations, and morphometrics to a PC or an internal image database. This includes automatic objective calibration and the ability to integrate barcode readers for automatic slide data entry, which can contribute to a comprehensive audit trail of diagnostic decisions and supporting data. The system also tracks XY position and objective magnification, providing valuable metadata for AI training and potentially for auditing purposes.

Physician Tip

Leverage Augmentiqs ARM to integrate AI and digital tools directly into your existing microscopy workflow without the need for whole-slide scanning, saving time and cost. Utilize the real-time augmented reality overlays for quantitative analysis, cell counting, and critical case data to enhance diagnostic precision. Engage in real-time telepathology for immediate consultations and peer review, sharing live views and annotations with colleagues globally. Remember that the AR overlay can be toggled off to prevent alert fatigue. The system's ability to save annotated images and track slide data can be valuable for documentation and future reference.

Augmentiqs ARM is designed as an Open API system, allowing for integration with various digital pathology software, AI algorithms, and Laboratory Information Systems (LIS). It can deploy any AI algorithm directly within the live microscopy workflow and synchronize with Whole Slide Imaging (WSI) files for comprehensive data sets. The system is compatible with all infinity-corrected light microscopes. It operates on a PC with Windows 7 or higher, with recommended specifications for optimal performance.

At a glance

Deployment On Premise (integrated With Existing Microscopes And PC)

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Details

Category	Clinical Decision Support & Reference, Pathology AI, Radiology & Imaging AI
Pricing	Unknown — unknown
Deployment	On-premise (integrated with existing microscopes and PC)
Compliance
BAA Available	Unknown AI-estimated
HIPAA Compliant	Unknown AI-estimated
FDA Status	Unknown AI-estimated Augmentiqs is FDA Class I exempt. The FDA encourages the development of innovative, safe, and effective medical devices, including those that incorporate augmented reality and virtual reality (AR/VR).
Integrations
EHR	Not specified
Specialties	Dermatology, Oncology, Pathology

What the Web Says

The Augmentiqs Augmented Reality Microscope (ARM) transforms existing analog microscopes into smart, connected devices, enabling real-time digital pathology. It integrates augmented reality, AI, and telepathology capabilities directly into the pathologist's workflow, aiming to improve diagnostic accuracy and efficiency, particularly in cancer detection.

Overall: Positive

Strengths

Cost-effective solution compared to full digital pathology systems, as it leverages existing microscopes.
Enables real-time telepathology and collaboration with remote colleagues, even with limited internet bandwidth.
Integrates AI and image analysis tools directly into the microscope's field of view, assisting with tasks like cancer detection and quantitative scoring.
Improves diagnostic accuracy and efficiency, with studies showing increased agreement among pathologists when using AI-assistance.
Maintains the optical quality and depth perception of traditional microscopy while adding digital functionalities.
Open API allows for integration with various digital systems and software, fostering a versatile pathology ecosystem.

Limitations

Some initial studies used accelerated computing units (like NVidia Titan Xp GPU) which might still be a cost challenge for widespread clinical adaptation.
The microdisplay used in some prototypes had limited brightness, requiring adjustments to the microscope light source for adequate contrast.
While improving efficiency, the technology still requires pathologists to adapt to a new workflow that integrates digital overlays.
The technology is still relatively new, with many studies and deployments being recent or ongoing.

Based on reviews from: Augmentiqs Website, NoCamels, PubMed, PMC - NIH, arXiv, YouTube, Luminate, Kinetic Vision, Google Research, DataDrivenInvestor, Reddit

Last updated: 2026-09-10

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Press & Coverage

NoCamels

Israeli Startup's Augmented Reality Tech Reinvents The Microscope For Pathologists

Augmentiqs, an Israeli startup, is transforming traditional analog microscopes into augmented reality (AR) devices for real-time digital pathology, enabling pathologists to work more effectively and connect remotely. The system integrates into existing microscopes, offering a cost-effective alternative to full digital pathology by allowing real-time examination with augmented projections.

2020-02

Augmentiqs

ARM Microscopy Study for Ki-67 Scoring - Augmentiqs

A peer-reviewed study published in the May 2020 Journal of Cancer Cytopathology, conducted at UPMC, demonstrated the functionality, accuracy, and time-saving advantages of Augmentiqs' Augmented Reality Microscope (ARM) for Ki-67 neuroendocrine tumor scoring. The study showed that ARM with embedded QuPath image analysis software can quantify samples in minutes, significantly reducing the time of manual counting.

2021-05

Augmentiqs

Augmentiqs Receives U.S. Patent

Augmentiqs announced it received a U.S. patent for its innovative method of improving pathology, highlighting the unique way its technology enhances microscopic examination. This patent recognizes the usefulness and innovation of the Augmentiqs system.

2023-05

Augmentiqs

Augmentiqs and SeeTrue Technologies Partner to Improve Pathology Research and Workflow

Augmentiqs partnered with eye-tracking leader SeeTrue Technologies to enhance pathology and microscope-based research. The collaboration aims to leverage the synergy of their technologies to significantly improve research and workflow in pathology.

2022-06

Defense Innovation Unit (DIU)

AI-Enabled Microscopes Could Bring More Timely, Accurate Cancer Detection

The U.S. Department of Defense's Predictive Health program is developing AI tools for early cancer detection, including an Augmented Reality Microscope (ARM) that uses a high-resolution camera and AR display to highlight abnormalities. Initial findings suggest AI-enabled technologies like ARM can increase diagnostic accuracy and efficiency in cancer detection.

2023-09

NIH (National Library of Medicine)

Augmented reality microscopy to bridge trust between AI and pathologists

A study published in Virchows Archiv explores an Augmented Reality Microscope (ARM) system, retrofitted with an Augmentiqs unit, to integrate AI into pathology workflows for PD-L1 CPS scoring. The ARM-AI framework allowed pathologists to evaluate AI assistance in real-time, improving both AI finetuning and pathologists' performance.

2025-05

GlobeNewswire

Inspirata and Augmentiqs Announce New Technical Partnership and Integration

Inspirata, a cancer informatics and digital pathology provider, announced a new technical partnership with Augmentiqs to bring real-time insights and digital case-sharing functionality directly into the pathologist's microscope via augmented reality. This collaboration introduces an innovative solution for casework, allowing pathologists to utilize AR to integrate critical case information and sharing features from Inspirata's Dynamyxu2122 solution.

2020-03

TweakTown

Google has built an AI-powered microscope designed to identify cancer cells

Google and the Department of Defense have collaborated to create an Augmented Reality Microscope (ARM) prototype with heads-up-display capabilities to speed up cancer cell identification. The ARM can be retrofitted to existing microscopes and displays visual indicators and heatmaps to assist doctors.

2023-09

Videos

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Frequently Asked Questions

How does the Augmentiqs ARM integrate AI into my existing pathology workflow?

The Augmentiqs ARM unit attaches to your current light microscope, allowing real-time overlay of AI-generated information directly into your eyepiece view. This means you can utilize AI algorithms for tasks like image analysis and cell counting without needing to digitize entire slides beforehand, streamlining your workflow.

What are the compliance and regulatory considerations for using Augmentiqs ARM with AI in a clinical setting?

When integrating any device into a medical instrument, regulatory approval and validation studies are crucial. Augmentiqs telepathology features are designed to be HIPAA compliant by not electronically transferring identifiable patient information during sessions, ensuring patient privacy.

What are the main limitations of the Augmentiqs ARM that I should be aware of?

One limitation noted in studies is that the ARM-AI framework may limit analysis to one region of interest (ROI) per biopsy case. Additionally, while AI assists, human involvement is still required for quantitative assessments, such as manually selecting stained nuclei for Ki-67 index calculation.

How does the cost of Augmentiqs ARM compare to other digital pathology solutions, especially those with AI capabilities?

The Augmentiqs ARM is presented as a cost-effective solution, being approximately 20 times less expensive than a high-capacity whole-slide scanner. It eliminates the need for expensive and time-consuming slide digitization, offering a more affordable route to incorporating digital and AI technologies into routine pathology.

What are the alternatives to Augmentiqs ARM for integrating AI into pathology, and what are their pros and cons?

Alternatives often involve whole-slide imaging (WSI) systems, which require digitizing entire glass slides before AI analysis. While WSI offers extensive digital archiving and remote access, it can be more time-consuming and significantly more expensive than ARM, which provides real-time AI integration directly through the microscope eyepiece.

How does Augmentiqs ARM ensure the trustworthiness and validation of its AI outputs for diagnostic purposes?

Augmentiqs aims to build trust by allowing pathologists active participation in the training and deployment of AI models. The system facilitates real-time evaluation of AI-assisted scoring against manual methods, ensuring pathologists can assess and validate the AI's usefulness in their practice.

Can the Augmentiqs ARM be used for telepathology and remote consultations, and how does it handle data security?

Yes, Augmentiqs ARM enables real-time telepathology for remote consultations and peer review. It securely transfers a live view of the tissue to remote participants using industry-standard encryption, while patient identifiable information is kept in the lab to maintain HIPAA compliance.