Align Technology

Tempe, Arizona, USA  All United States companies → Founded 2020 (as dentalXrai GmbH, acquired by Align Technology in 2022)
Medical Device / Hardware Specialty-Focused AI
Dentistry
Dental AI
Publicly Traded (NASDAQ: ALGN) — Approximately $140 million (pre-IPO funding for Align Technology, Inc.)

Products

Align X-ray Insights
Align Technology
Dental AI
Align X-ray Insights by Align Technology is an AI-powered software solution designed to enhance dental diagnostics by automatically analyzing 2D dental radiographs for abnormalities like caries, periapical radiolucencies, and periodontal bone loss, improving treatment planning and patient communication.
Align’s X-ray Insights
Align Technology
Dental AI
Align's X-ray Insights is a software-only computer-assisted detection device (CADe) that employs AI to automatically analyze and annotate radiographic abnormalities. Giving you time back to focus on delivering exceptional patient care.

See all 2 products →

About Align Technology

Align X-ray Insights, a key component of the broader Align Digital Platform, is an advanced software-only computer-assisted detection (CADe) device designed to revolutionize dental diagnostics for physicians. Leveraging artificial intelligence and deep learning techniques, it automatically analyzes and annotates radiographic abnormalities in 2D dental radiographs, including panoramic, periapical, and bitewing images. This technology aims to streamline diagnostic workflows, enhance the accuracy of pathology detection, and provide valuable time-saving optimizations for dental practices. [1, 5, 9, 11, 12]

For dental professionals, Align X-ray Insights offers a sophisticated tool to support more informed treatment planning and the early detection of various oral health conditions. The software generates detailed reports, provides automatic tooth charting, and overlays color-coded annotations directly onto radiographs, making complex findings intuitive and easy to interpret. It is capable of identifying conditions such as caries, periapical radiolucencies, periodontal bone loss, calculus, fillings, crowns, bridges, implants, root-canal fillings, impacted teeth, and the proximity of lower molars to the mandibular canal. [4, 5, 8, 9, 10, 14]

Beyond diagnostic precision, Align X-ray Insights significantly empowers patient communication and engagement. By visually illustrating oral health conditions and treatment options, it helps build patient trust and has been shown to increase treatment acceptance for restorative procedures. While providing powerful AI-driven analysis, the system is intended to be used in conjunction with a doctor’s evaluation and not as a sole basis for diagnosis, ensuring that clinical autonomy is maintained. It integrates seamlessly with the Align Digital Platform, including iTero intraoral scanners, further advancing digital dentistry. [1, 4, 9, 10, 12, 13]

Focus Areas

Clear Aligners Intraoral Scanners CAD/CAM Software AI-powered Dental Diagnostics AI-assisted Treatment Planning Digital Dentistry Orthodontics Restorative Dentistry

Business Intelligence

Key InvestorsABS Ventures, The Carlyle Group, Oak Hill Capital Partners, Kleiner Perkins Caufield & Byers, Domain Partners, QuestMark
PartnershipsUniversity of Bern (epidemiological study collaboration)
AcquisitionsCadent (2011), exocad (2020), dentalXrai (2022), Cubicure (2023)
TechnologyAlign Digital Platform (cloud-native, AI-driven algorithms, deep learning, integrated suite of technologies and services)
FDA Clearances3 cleared products (estimated)

What Physicians Need to Know

Clear Aligners (Invisalignu00ae System)
Align Technology pioneered the invisible orthodontics market with the Invisalignu00ae System, offering a discreet and comfortable alternative to traditional braces. Key innovations include SmartTracku2122 material for optimal control of tooth movements, SmartForceu2122 features (attachments like Bite Ramps, Precision Cuts, Power Ridge) for predictable force delivery, and SmartStagingu2122 technology for precise sequencing of tooth movements. The system treats a wide range of cases, from simple to complex, across adults, teens, and growing children (Invisalign First), including solutions for mandibular advancement.
Intraoral Scanners (iTerou2122)
The iTerou2122 intraoral scanners (e.g., iTero Elementu2122 5D, iTero Luminau2122) provide highly detailed 3D digital scans, replacing traditional impressions. Features include Near-Infrared Imaging (NIRI) for radiation-free interproximal caries detection, a built-in high-definition intraoral camera, and iTero TimeLapse technology for monitoring tooth movement over time. The iTero Lumina boasts a 3x wider field of capture and a 50% smaller, lighter wand for enhanced user and patient comfort, delivering faster and more accurate scans.
CAD/CAM Software (exocadu2122)
Align Technology acquired exocadu2122, integrating its CAD/CAM software into the Align Digital Platform. This software streamlines workflows for dental professionals and labs, enabling the design and fabrication of various restorations such as crowns, bridges, and veneers. It facilitates enhanced collaboration between doctors and labs through a single, secure channel.
AI-powered Dental Diagnostics (Alignu2122 X-ray Insights)
Align X-ray Insights is an AI-powered software tool that automatically analyzes 2D dental radiographs to enhance diagnostic accuracy. It detects conditions such as caries, periapical radiolucencies, and periodontal bone loss, providing detailed reports, automatic tooth charting, and color overlays of abnormalities. This tool is designed to support more informed treatment planning and improve patient communication.
AI-assisted Treatment Planning (ClinChecku00ae Live Plan, Virtual Care AI)
Align's ClinChecku00ae software, powered by AI-driven staging algorithms, allows for detailed 3D treatment planning and outcome simulation. The new ClinChecku00ae Live Plan feature automates the generation of initial doctor-ready treatment plans within minutes, significantly reducing the planning cycle. Invisalignu00ae Virtual Care AI offers remote monitoring capabilities, using AI-assisted algorithms for automatic assessment of treatment progress and automated notifications for patients, streamlining practice workflows.
Digital Dentistry & Integrated Workflow
Align Technology offers a comprehensive Align Digital Platform, an integrated suite of hardware, software, and services that provides a seamless, end-to-end digital workflow for orthodontic and restorative treatments. This platform connects digital patient capture (iTero scanners), cloud-based treatment planning (ClinCheck), and high-throughput custom manufacturing, enhancing efficiency and patient experience.
Orthodontics & Restorative Dentistry
Align Technology's solutions span both orthodontics and restorative dentistry. For orthodontics, the Invisalign system addresses a broad spectrum of malocclusions. In restorative dentistry, iTero scanners are integral for precise digital impressions used in crowns, bridges, and implant planning, with integration into CAD/CAM systems for fabrication and the iTero Design Suite for chairside design.
Physician Tip

For physicians, Align Technology stands out due to its **integrated digital ecosystem** that streamlines the entire patient journey from diagnosis to retention. The **precision and predictability** offered by SmartTracku2122 material, SmartForceu2122 features, and AI-driven ClinChecku00ae treatment planning lead to more consistent and effective patient outcomes. The **iTerou2122 intraoral scanners** significantly improve workflow efficiency by providing fast, accurate, and comfortable digital impressions, enhanced by NIRI technology for early caries detection. **AI-powered diagnostic tools like Alignu2122 X-ray Insights** and **AI-assisted remote monitoring via Invisalignu00ae Virtual Care AI** enhance diagnostic accuracy, facilitate patient education, and reduce chair time, allowing for more efficient practice management and improved patient engagement. Align's commitment to **clinical education and a vast clinical dataset** (over 22 million Invisalign patients) further empowers doctors to treat a wider range of cases with confidence.

Align Technology's core strength lies in its **Align Digital Platform**, which seamlessly integrates its proprietary hardware (iTerou2122 scanners) and software (Invisalignu00ae ClinChecku00ae, exocadu2122 CAD/CAM, Alignu2122 X-ray Insights, Alignu2122 Oral Health Suite, Invisalignu00ae Virtual Care AI). This creates an **end-to-end digital workflow** that connects doctors, labs, and patients, facilitating efficient data transfer, collaborative treatment planning, and comprehensive patient management. The iTerou2122 scanners are designed for **certified connectivity with restorative and orthodontic labs**, third-party treatment planning, custom implant abutment, and chairside milling systems, ensuring broad compatibility within the digital dentistry landscape.

Products by Align Technology

2 products in the directory

Align X-ray Insights
Align Technology
Dental AI
Align X-ray Insights by Align Technology is an AI-powered software solution designed to enhance dental diagnostics by automatically analyzing 2D dental radiographs for abnormalities like caries, periapical radiolucencies, and periodontal bone loss, improving treatment planning and patient communication.
Align’s X-ray Insights
Align Technology
Dental AI
Align's X-ray Insights is a software-only computer-assisted detection device (CADe) that employs AI to automatically analyze and annotate radiographic abnormalities. Giving you time back to focus on delivering exceptional patient care.

Reviews & Opinions

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Press & Coverage

Align Technology Investor Relations
Align Technology to Announce Second Quarter 2026 Results on July 29, 2026
Align Technology is scheduled to announce its second quarter 2026 financial results on July 29, 2026. This announcement will provide an update on the company's financial performance.
2026-07
Align Technology Investor Relations
Align Technology Statement on European Commission Proceeding
Align Technology has issued a statement regarding a proceeding initiated by the European Commission. The company is cooperating fully with the investigation into its commercial practices.
2026-06
Align Technology Investor Relations
Align Technology Announces Board Leadership Transition
Align Technology announced that C. Raymond Larkin, Jr. will retire as Chairman, and Kevin Conroy will be appointed Chairman effective July 1, 2026.
2026-06
Compendium
Align Technology Announces Recipients of 2026 University Research Awards
Align Technology announced the recipients of its 15th Annual Research Award Program, providing funding to university-based investigators in orthodontics and dentistry. The funded studies cover various orthodontic and dental research topics.
2026-06
Competition Policy International
EU Opens In-Depth Antitrust Investigation Into Align Technology's Invisalign Sales Practices
The European Commission has launched a formal antitrust investigation into Align Technology to determine if its sales practices, particularly linking Invisalign sales with iTero scanners, violate EU competition rules.
2026-06
Align Technology Investor Relations
Align Technology Announces First Quarter 2026 Financial Results, $200M Stock Repurchase, and Reaffirms Fiscal 2026 Guidance
Align Technology reported first-quarter 2026 total revenues of $1,040.1 million, a 6.2% increase year-over-year, and announced a $200 million stock repurchase. The company also reaffirmed its fiscal year 2026 guidance.
2026-04
Business Wire
Align Technology Recognized for the Fifth Consecutive Year as a LexisNexis Top 100 Global Innovator, Earning u201cFive-Year Top 100 Global Innovatoru201d Distinction
Align Technology has been recognized for the fifth consecutive year as a Top 100 Global Innovator in the 2026 LexisNexis Innovation Momentum report, highlighting its advancements in AI-driven treatment planning and 3D printing innovations.
2026-04
Business Wire
Align Technology Launches Align X-ray Insights, an AI Computer-Aided Detection Software, in the European Union and United Kingdom
Align Technology launched Align X-ray Insights, an AI computer-aided detection software, in the EU and UK, designed to support doctors in diagnosing dental and oral health conditions and improving patient engagement.
2025-03

Frequently Asked Questions

Align Technology's Digital Platform seamlessly integrates the Invisalign System of clear aligners, iTero intraoral scanners, and exocad CAD/CAM software to create an end-to-end digital workflow. This platform enables dental professionals to capture precise 3D scans, plan orthodontic and restorative treatments, and design restorations, enhancing efficiency and patient outcomes.
Align Technology offers AI-powered solutions like Align X-ray Insights, which analyzes 2D radiographs for dental conditions such as caries and bone loss, aiding in diagnosis and patient education. Additionally, Invisalign Virtual Care AI assists with remote monitoring of aligner fit and patient compliance, while ClinCheck software leverages AI for efficient and personalized treatment planning, including ortho-restorative cases.
Patient compliance is crucial for Invisalign treatment success, with recommended wear times of 20-22 hours daily. Align Technology supports compliance through tools like Invisalign Virtual Care AI for remote monitoring and automated patient notifications. They also provide extensive clinical education and training for doctors to effectively manage and motivate patients.
While patient pricing for Invisalign is determined by the individual doctor based on the treatment plan, Align Technology offers various Invisalign packages to suit different case complexities. For professional support, Align provides comprehensive clinical education programs, training centers, webinars, and direct support channels for both Invisalign providers and iTero users.
Align Technology holds a strong market position as a global leader in clear aligners and digital orthodontics, reporting record revenues of $4.0 billion in 2025 with robust gross profit margins and minimal debt. The company continues to invest significantly in R&D and innovation, particularly in AI-driven solutions and international market expansion, positioning it for sustained growth.
Align Technology provides comprehensive solutions for both orthodontics and restorative dentistry through its integrated platform. Invisalign clear aligners address a wide range of malocclusions, while iTero intraoral scanners offer precise digital impressions for both aligner treatment and restorative procedures. The exocad CAD/CAM software and iTero Design Suite further enable in-practice design and fabrication of various dental restorations.
Align Technology actively engages in strategic partnerships to broaden its impact and technological capabilities. Examples include collaborations with dentalcorp to expand access to Invisalign treatment and agreements with companies like DENTSPLY Implants for digital implant restorative workflows. Align also supports academic research through award programs, fostering innovation in orthodontics and dentistry.

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