About Anumana
Anumana is an AI-driven health technology company co-founded by nference and Mayo Clinic, dedicated to transforming cardiovascular care. Their core mission is to leverage cutting-edge artificial intelligence and translational science to decipher the electrical signals of the heart, enabling earlier and more accurate diagnosis, treatment, and interventions in cardiology.
The company develops and commercializes software-as-a-medical-device (SaMD) solutions, which include FDA-cleared ECG-AI algorithms. These algorithms analyze standard 10-second or 12-lead electrocardiograms (ECGs) to detect subtle patterns invisible to the human eye, revealing critical information about heart conditions. For instance, their FDA-cleared ECG-AI LEF (low ejection fraction) technology identifies reduced heart function, and they have the first and only FDA-cleared ECG-AI algorithm for cardiac amyloidosis using standard 12-lead ECGs. Anumana’s algorithms are built upon extensive proprietary datasets, including over 25 million longitudinal patient data from leading institutions and more than 100,000 paired ECGs and echocardiograms, ensuring high accuracy and representation across diverse patient populations.
Beyond diagnostics, Anumana is expanding its focus into perioperative cardiac care, developing novel generative AI imaging and visualization technologies, and real-time procedural support tools for structural heart, interventional cardiology, and electrophysiology procedures. Their solutions are designed to integrate seamlessly into existing clinical workflows, providing physicians with crucial, actionable insights at the point of care to improve patient outcomes throughout the entire cardiac care continuum.
Focus Areas
Business Intelligence
| Key Investors | nference, Mayo Clinic Ventures, Matrix, Matrix Capital Management, NTT Venture Capital, Boston Scientific, MedTech Innovator |
| Partnerships | Pfizer, Novartis Pharmaceuticals Corporation, Philips, AliveCor, American College of Cardiology (ACC) |
| Acquisitions | NeuCures (also referred to as NeuTrace) |
| Technology | ECG-AI Platform, multimodal generative AI platform, Software as a Medical Device (SaMD), nference's nSights real-world evidence generation platform, integrates with EHR systems and ECG platforms, cloud-native |
| FDA Clearances | 3 cleared products (estimated) |
What Physicians Need to Know
For physicians, Anumana's AI tools transform routine 12-lead ECGs into powerful diagnostic instruments, enabling earlier detection of hidden cardiovascular conditions like low ejection fraction, pulmonary hypertension, hyperkalemia, and cardiac amyloidosis. This can lead to more timely interventions, optimize the utilization of more expensive diagnostic tests like echocardiograms, and improve diagnostic confidence at the point of care. The integration into existing clinical workflows means minimal disruption, allowing for enhanced cardiac assessment and more appropriate referrals to specialists, ultimately improving patient outcomes and potentially preventing disease progression.
Anumana's platform is designed for seamless integration across diverse healthcare systems, including EHRs and ECG information management systems. They have established key partnerships, such as with Philips for their ECG AI Marketplace, making their FDA-cleared LEF algorithm available through Philips' ECG portfolio. Additionally, they are collaborating with InfoBionic.Ai to integrate their ECG-AI algorithms into remote cardiac telemetry platforms, expanding their reach to wearable lower-lead ECGs in patients' homes.
What the Web Says
Anumana is an AI-driven health technology company that develops ECG algorithms for early disease diagnosis and intervention, with a focus on cardiovascular conditions. Their technology analyzes the heart's electrical signals to reveal insights beyond human detection capabilities, aiming to identify at-risk patients earlier and inform ongoing care. The company was founded in 2021 as a collaboration between the Mayo Clinic and nference. Anumana has received FDA clearance for its cardiac ECG-AI algorithm to detect low ejection fraction (LEF) and for its pulmonary hypertension algorithm, with a cardiac amyloidosis algorithm also receiving Breakthrough Device Designation.
Overall: PositiveStrengths
- AI-driven ECG algorithms enable early disease diagnosis and intervention, particularly for cardiovascular conditions.
- Technology is built on extensive patient records (over 22 million) and validated through numerous peer-reviewed publications.
- Algorithms provide clinically validated insights and integrate seamlessly into existing clinical workflows without requiring new hardware.
- Focus on proactive care, improving patient outcomes and potentially reducing healthcare costs.
- Received FDA clearances and Breakthrough Device Designation for key algorithms.
- Strong commitment to excellence in the development and manufacturing of regulated medical devices, as evidenced by ISO 13485 certification.
Limitations
- Limited public reviews available on platforms like G2, Glassdoor, and Capterra specifically for Anumana, making it difficult to gauge widespread user satisfaction for their products or as an employer.
- Some search results were for similarly named companies (e.g., Animana, Amana, Humana, Anaplan, Anomalo, Asana, Lumana, Yumana, uman.ai), which could lead to confusion when researching.
Based on reviews from: anumana Inc Average Salary, Pay Ranges & Benefits, Anumana - Jobs, Funding & Reviews - Employbl, Working at Humana: 8,280 Reviews | Indeed.com, Working as an IT at Humana: Employee Reviews | Indeed.com, Anumana - Unlocking the Language of the Heart, Animana Reviews 2026. Verified Reviews, Pros & Cons - Capterra, IT Operations & Helpdesk reviews at Humana in Remote | Indeed.com, Working at amana in Houston, TX: Employee Reviews | Indeed.com, Working as a Help Desk Analyst at Humana: Employee Reviews | Indeed.com, Amana - Reliable? : r/hvacadvice - Reddit, Anumana Makes Educated Inferences in Heart Failure, Cardiac Care AI Company, Anumana, Announces Receipt of ISO 13485 Certification | DAIC, Anumana: Interview With CEO Maulik Nanavaty About The AI-Driven Health Technology Company - Pulse 2.0, Working at amana: Employee Reviews | Indeed.com, Working as an Analyst at Humana: 70 Reviews | Indeed.com, Capterra Pros and Cons | User Likes & Dislikes - G2, Lumana Reviews 2026: Details, Pricing, & Features - G2, Capterra Reviews 2026: Details, Pricing, & Features | G2, Anaplan Reviews 2026: Details, Pricing, & Features | G2, Yumana Software Pricing, Alternatives & More 2026 - Capterra, Asana Software Pricing, Alternatives & More 2026 | Capterra, Asana Reviews 2025 - G2, Anomalo Reviews 2026: Details, Pricing, & Features - G2, uman.ai Reviews 2026: Details, Pricing, & Features - G2
Last updated: 2026-07-19
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