Products

INT Contour
Carina Medical
Oncology AI
AI-Powered Segmentation With Automatic Quality Assurance for radiation oncology and radiology applications, supporting efficient radiation treatment planning.

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About Carina Medical

Carina Medical, also known as Carina AI, is a healthcare artificial intelligence (AI) company specializing in medical image analysis software for radiation oncology and radiology applications. The company develops cutting-edge AI technologies aimed at enhancing the efficiency and accuracy of clinical practices.

Their software provides novel solutions for radiation treatment, including advanced capabilities for both computed tomography (CT) and magnetic resonance imaging (MRI)-based organ segmentation. Carina Medical’s site-specific segmentation models are designed to improve the robustness of their AI systems, thereby streamlining workflows for radiation therapy and ultimately contributing to improved cancer treatment outcomes. Beyond oncology, their offerings extend to innovative medical de-identification and data management platforms, automatic ventricle segmentation for hydrocephalus diagnosis, and advanced AI tools for comprehensive cancer diagnosis, treatment, and monitoring from multi-modality imaging.

Focus Areas

Medical image analysis Radiation oncology Radiology applications CT and MRI-based organ segmentation Site-specific segmentation models Cancer diagnosis Cancer treatment Cancer monitoring OAR and target segmentation Independent dose verification Medical de-identification Data management Ventricle segmentation for hydrocephalus diagnosis

Business Intelligence

Key InvestorsLaunch Blue, National Cancer Institute, U.S. Department of Health and Human Services, KY SBIR Matching Fund, National Institutes of Health
PartnershipsDuke University, Johns Hopkins Hospital, Mayo Clinic (for product deployment and testing)
TechnologyAI-based medical image analysis software, Machine learning-based approach, Independent Monte Carlo algorithm, Software-only product, Deployed within a hospital's private network on a workstation with an advanced graphics processing unit (GPU) and runs as a service
FDA Clearances2 cleared products (estimated)

What Physicians Need to Know

Medical Image Analysis & AI-Powered Segmentation
Carina Medical (Carina AI) specializes in advanced AI-powered medical image analysis, offering fully customizable OAR (Organs At Risk) and target segmentation. Their INTContour product can automatically segment over 120 organs and lymph node groups from CT, MRI, and PET/CT modalities, supporting built-in or custom protocols. This includes site-specific segmentation models for head and neck, thorax, abdomen, and male pelvis.
Radiation Oncology & Independent Dose Verification
For radiation oncology, Carina Medical provides tools for precise treatment planning. Their INTDose software offers fast and accurate independent dose verification using Monte Carlo 3D dose verification algorithms, ensuring comprehensive quality assurance in radiation treatment planning.
Cancer Diagnosis, Treatment & Monitoring
The OncoAI Suite offers advanced AI tools to improve cancer diagnosis, treatment, and monitoring across multi-modality imaging. This includes specialized modules for lymph node detection, brain tumor segmentation, and lung nodule detection, enabling precise quantification and longitudinal tracking of tumor changes.
Medical De-identification & Data Management
Carina Medical's DeIdentifier platform provides an innovative, HIPAA-compliant solution for medical de-identification and data management. It removes Protected Health Information (PHI) from DICOM RT modalities (headers, burned-in text, facial features) while preserving the research value of the data. It also supports project-based data organization and annotation features.
Ventricle Segmentation for Hydrocephalus Diagnosis
QuantBrain - Ventricle offers automatic segmentation and measurement of ventricles for hydrocephalus diagnosis. It supports multi-modality imaging (CT, T1, T2, FLAIR MRI), is robust against various disease conditions (tumor, shunt, infarct), and provides automatic Evans index calculation, reporting, and longitudinal tracking for both pediatric and adult populations.
Key Differentiators & Technology Stack
Carina Medical's key differentiators include fully customizable AI-powered segmentation with automatic quality assurance, the ability for users to train custom models, robust performance across diverse clinical conditions, and comprehensive de-identification that maintains data utility for research. Their technology stack leverages cutting-edge AI/Deep Learning/Machine Learning, operates as web-based systems, is DICOM compliant, supports multiple imaging modalities (CT, MRI, PET/CT), and utilizes Monte Carlo algorithms for dose verification. Deployment can be within a hospital's private network on GPU-equipped workstations, supporting Ubuntu and Windows.
Physician Tip

For physicians, Carina Medical's solutions offer significant advantages in improving the accuracy and efficiency of clinical workflows. The AI-powered segmentation (INTContour) can drastically reduce manual contouring time and inter-observer variability in radiation therapy planning, leading to more precise and standardized treatments. The OncoAI Suite aids in earlier and more accurate cancer diagnosis and monitoring. Independent dose verification (INTDose) provides an essential layer of safety and quality assurance. Furthermore, QuantBrain - Ventricle offers rapid and robust quantitative analysis for hydrocephalus, crucial for diagnosis and longitudinal patient management. The ability to customize protocols and even train AI models means the tools can be tailored to specific departmental needs and preferences. The DeIdentifier ensures patient data privacy while enabling valuable research and AI development within a HIPAA-compliant framework. These tools empower physicians with advanced insights and streamlined processes, ultimately enhancing patient care and operational efficiency.

Carina Medical's products are designed for seamless integration into existing clinical environments. INTContour, for example, operates as a stand-alone web-based system or integrates with applications via Automatic Workflow or Treatment Planning System (TPS) Connectivity, efficiently transferring segmented studies back to the main application. DeIdentifier supports uploading local data or retrieving it remotely from PACS, and INTDose can be installed locally, run as a web service, or called using vendor APIs. This flexibility ensures compatibility with diverse hospital IT infrastructures and clinical workflows.

Products by Carina Medical

1 product in the directory

INT Contour
Carina Medical
Oncology AI
AI-Powered Segmentation With Automatic Quality Assurance for radiation oncology and radiology applications, supporting efficient radiation treatment planning.

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Press & Coverage

Ronovo Surgical
Carinau2122 Makes History: NMPA Approves China's First Modular Robotic Platform for 4 Surgical Specialties!
Ronovo Surgical's Carinau2122 laparoscopic surgical robot received market approval from China's NMPA, becoming the first modular laparoscopic surgical robot in China with full-indication approval for four major specialties: general surgery, thoracic surgery, gynecology, and urology.
2025-03
G-MedTech
Ronovo Surgical's Modular Surgical Robot Carinau00ae Approved in China for Four Major Specialties
Ronovo Surgical's Carinau00ae laparoscopic surgical robot has been approved by China's NMPA, marking a significant milestone as the first modular surgical robot in China to receive full-indication approval for general surgery, thoracic surgery, gynecology, and urology.
2025-03
Innovaccer Inc.
Carina Health Network Partners with Innovaccer to Advance Value-Based Care for Over 1.5 Million Coloradans
Carina Health Network, a Colorado-based nonprofit, partnered with Innovaccer to leverage its Healthcare Intelligence Cloud for accelerating the transition to value-based care and improving outcomes for over 1.5 million Coloradans.
2026-03
GlobeNewswire
Carina Biotech Doses First Patient in Phase 1/2a Clinical Trial of LGR5-Targeted CAR-T Cell Therapy
Carina Biotech announced the dosing of the first patient in a Phase 1/2a clinical trial for its LGR5-targeted CAR-T cell therapy candidate, CNA3103, for metastatic colorectal cancer.
2023-12
BioSpace
Ronovo Surgical Closes $44M Series B Financing to Advance Carinau2122 Platform Towards Commercialization and International Expansion
Ronovo Surgical successfully closed a $44 million Series B financing round to accelerate the commercialization of its Carinau2122 Platform in China and prepare for international expansion.
2024-06
Biotechnology News
Carina Biotech completes $5 million capital raise
Carina Biotech successfully completed a $5 million capital raise from existing and new shareholders to support the continued progress of its CAR-T CNA3103 clinical trial for advanced colorectal cancer.
2025-04
Clinical Trials Arena
FDA clears Carina Biotech's IND to begin colorectal cancer therapy trial
The US FDA issued a 'safe to proceed' letter for Carina Biotech's investigational new drug application to commence a Phase I/IIa clinical trial of CNA3103 for advanced colorectal cancer.
2023-03
PMC (Surgical and Radiologic Anatomy)
Anatomy and variations of the carina and its cartilaginous makeup: a cadaveric study
A cadaveric study investigated the detailed morphology of the carina, finding that most carinal cartilages are composed of the most inferior tracheal ring or bronchial cartilages, with the right main bronchial cartilage being the most common contributor.
2025-02

Frequently Asked Questions

Carina Medical offers several AI solutions, including INTContour for automated OAR and target segmentation across CT, MRI, and PET/CT modalities, and OncoAI Suite for advanced cancer diagnosis, treatment, and monitoring. They also provide INTDose for fast and accurate independent dose verification in radiation treatment planning.
Carina Medical provides QuantBrain - Ventricle, an AI-powered solution for automatic segmentation and measurement of ventricles from CT and MRI, specifically designed for hydrocephalus diagnosis. This tool includes automatic Evans index calculation and supports longitudinal tracking for monitoring disease progression.
Carina Medical's DeIdentifier platform offers innovative medical de-identification and data management, ensuring HIPAA compliance by removing Protected Health Information (PHI) from DICOM RT modalities. This includes features like burned-in text removal, mask-based defacing, and report de-identification, while preserving research value.
Carina Medical's DeIdentifier platform ensures full HIPAA compliance for patient data de-identification. Additionally, Carina AI offers comprehensive support for FDA regulatory requirements, including 510(k) submissions, to ensure their AI tools meet relevant guidelines and standards.
Carina Medical provides customizable segmentation protocols within INTContour, allowing users to adjust regions of interest, naming conventions, and Treatment Planning System (TPS) settings to match specific workflow needs. Their solutions also feature built-in quality assurance and tools for manual editing and annotation.
Carina AI is a startup that originated from multiple labs at the University of Virginia and the University of Kentucky, focusing on developing cutting-edge AI-powered healthcare software solutions. The company is dedicated to pioneering medical technology with a profound commitment to safety, efficacy, and collaboration.
Carina AI has a foundation in academic research, having spun out of university labs, and has strategic partnerships with top hospitals like Duke and Johns Hopkins where their products are deployed and tested. Pricing for their enterprise AI solutions is typically obtained by contacting the company directly for a quote tailored to specific requirements.

Investors

Who's funded Carina Medical.

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