Informai (for RadOncAI product) / Global Network for AI in Radiation Oncology (for RadoncAI.net)

Houston, Texas, USA  All United States companies → — Founded 2017
Imaging AI Specialist Specialty-Focused AI
Seed — $2.0M

Products

RadOncAI
Informai (for RadOncAI product) / Global Network for AI in Radiation Oncology (for RadoncAI.net)
Oncology AI
RadOncAI is an AI solution by Informai designed to optimize and enhance radiation oncology workflows, improving efficiency and accuracy in treatment planning and delivery.

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About Informai (for RadOncAI product) / Global Network for AI in Radiation Oncology (for RadoncAI.net)

InformAI is a healthcare AI company that develops AI-driven enterprise software solutions, specializing in critical fields such as radiology, radiation oncology, and high-acuity informatics. Their flagship product, RadOncAI, is an FDA-cleared software-as-a-medical-device (SaMD) designed to enhance clinical decision-making in radiation therapy. It provides AI-guided dose prediction from CT simulations and clinician-defined treatment-planning structures for adult head-and-neck malignant or benign disease. The software aims to generate optimized radiation plans that target tumors while minimizing exposure to adjacent healthy tissues, ultimately improving consistency, efficiency, quality, and safety in radiation oncology workflows.

Beyond RadOncAI, InformAI’s product pipeline includes TransplantAI and SinusAI. TransplantAI is a donor-recipient informatics platform that leverages AI to enable granular transplant decisions at the point of care, addressing organ scarcity and allocation inefficiency. SinusAI is designed to advance CT imaging diagnostics with AI-enabled precision and efficiency. InformAI’s solutions are developed to integrate into hospital workflows and existing reimbursement frameworks, with a focus on solving workflow bottlenecks, accelerating diagnosis and decision-making, and improving clinician productivity.

Focus Areas

radiology radiation oncology transplant decision support CT diagnostics AI-driven clinical software medical imaging patient outcome prediction

Business Intelligence

Key InvestorsDEFTA Partners, Joyance Partners, Social Starts, National Science Foundation
PartnershipsNvidia's Inception Program, Microsoft for Startups, Amazon Activate, University of Texas Southwestern Medical Center (UTSW), Texas Medical Center
TechnologyAI-driven enterprise software, AI-enabled image classifiers, patient outcome predictors, machine learning, deep learning
FDA Clearances1 cleared products (estimated)

What Physicians Need to Know

Specialization: Radiation Oncology
InformAI's flagship product, RadOncAI, is an AI-enabled software for radiation therapy dose planning, specifically for head and neck cancer patients. It optimizes treatment dose plans to target tumors while minimizing exposure to healthy tissues.
Specialization: Transplant Decision Support
TransplantAI is a donor-recipient informatics platform that utilizes AI to enable granular transplant decisions at the point of care. It leverages data from over 500 parameters per organ and CT images to enhance decision-making for heart and lung transplant outcomes.
Specialization: CT Diagnostics
SinusAI is a product in InformAI's pipeline that aims to advance CT imaging diagnostics with AI-enabled precision and efficiency.
Key Differentiator: Clinical Focus & Fit-for-Purpose Products
InformAI emphasizes targeted solutions for specific clinical pain points rather than one-size-fits-all imaging AI.
Key Differentiator: Enterprise-Grade Integration
The company develops scalable, enterprise software designed to integrate into hospital workflows and existing reimbursement frameworks.
Key Differentiator: Clinical Provenance & Partnerships
Product development is tied to the Texas Medical Center ecosystem, ensuring clinical relevance.
Technology Stack: AI/Machine Learning/Deep Learning
InformAI develops sophisticated machine learning and deep learning products to enhance clinical decision-making, optimize treatment planning, and improve patient outcomes. Their products are AI-driven enterprise software solutions.
Regulatory Status
InformAI has received FDA 510(k) clearance for its RadOncAI radiation dose planning software-as-a-medical-device (SaMD).
Physician Tip

For physicians, InformAI's products, like RadOncAI, offer the potential for generating high-quality radiation dose plans more efficiently, assisting in delivering optimized and clinically achievable plans in a fraction of the time. This can lead to substantial clinical productivity and cost savings. The AI-driven tools aim to improve consistency, efficiency, quality, and safety in radiation care by providing expert-level plans, generating plans in minutes, improving IMRT/VMAT protocols, and reducing off-target radiation. For transplant specialists, TransplantAI provides real-time predictive insights for donor-recipient matching, assessing multi-outcome risks, and improving transplant matching and patient outcomes. The company's focus on 'fit-for-purpose' AI means their solutions are designed to address specific clinical pain points, aiming to accelerate diagnosis, improve clinician productivity, and provide decision support that integrates into existing hospital workflows.

InformAI's enterprise-grade software is designed for seamless and scalable integration into hospital workflows and existing reimbursement frameworks. RadOncAI, for instance, accepts CT simulation, target, and organ-at-risk inputs and exports DICOM RT Dose to compatible treatment-planning or DICOM-RT workflows. They partner with elite medical institutions and deploy directly with channel partners. Strategic partners include Nvidia's Inception Program, Microsoft for Startups, and Amazon Activate.

Products by Informai (for RadOncAI product) / Global Network for AI in Radiation Oncology (for RadoncAI.net)

1 product in the directory

RadOncAI
Informai (for RadOncAI product) / Global Network for AI in Radiation Oncology (for RadoncAI.net)
Oncology AI
RadOncAI is an AI solution by Informai designed to optimize and enhance radiation oncology workflows, improving efficiency and accuracy in treatment planning and delivery.

What the Web Says

Informai (for RadOncAI product) and the Global Network for AI in Radiation Oncology (for RadoncAI.net) operate in the rapidly evolving field of AI in radiation oncology. RadOncAI is an FDA-cleared radiology AI listing for radiotherapy planning, specifically for adult head-and-neck malignant or benign disease, providing AI-guided dose prediction. The broader application of AI in radiation oncology is seen as a transformative force, with numerous studies and implementations focusing on improving efficiency, accuracy, and personalized patient care in areas like image processing, treatment planning, and outcome prediction. However, there's also a recognized need for robust validation, clear clinical utility, and careful integration into existing workflows to ensure responsible deployment and address concerns about potential biases and the need for human oversight.

Overall: Mixed

Strengths

  • AI-guided dose prediction for head-and-neck radiotherapy planning.
  • FDA-cleared radiology AI listing.
  • Potential to improve speed, accuracy, and quality of radiation therapy decision-making.
  • Can automate routine tasks and analyze complex data sets quickly.
  • Aids in improving efficiency and reducing errors in radiology reporting.
  • Contributes to more personalized treatment and improved patient safety.

Limitations

  • No exact-product price found in public evidence.
  • Deployment details and security/privacy controls for the exact configuration are not established in public FDA decision material.
  • AI models may not provide clear clinical utility, and added value remains a key question.
  • Integration into existing workflows requires coordinated, multi-institutional collaboration.
  • Potential for false positives and false negatives in diagnostic AI tools, leading to additional cognitive burden.
  • Radiation oncologists may not be trained for detailed delineation of complex structures, potentially leading to over-reliance on AI tools without adequate review.

Based on reviews from: G2, Google Search, Reddit, Slashdot, Indeed.com, Trustpilot, CancerNetwork, Accuray, FeaturedCustomers, YouTube

Last updated: 2026-09-26

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Press & Coverage

InformAI
InformAI Receives FDA 510(k) Clearance for RadOncAI Radiation Therapy Dose Planning Software
InformAI has received 510(k) clearance from the FDA for its RadOncAI radiation dose treatment planning software-as-a-medical-device (SaMD). This software is designed to enable AI-driven radiation therapy, optimizing radiation plans to target tumors while minimizing exposure to healthy tissues.
2026-06
Dealroom News
InformAI lands $1M NIH grant to expand AI organ-matching tool
InformAI has secured $1 million in grant funding for the second year of a National Institutes of Health (NIH) Fast-Track grant to further develop TransplantAI, its clinical decision-support tool for organ transplants. This non-dilutive government backing validates the increasing role of AI in high-stakes clinical decisions.
2026-09
CancerNetwork
AI's Evolving Role in Radiation Oncology
Artificial intelligence is becoming a daily reality in oncology, shaping various aspects of cancer care from treatment planning to patient navigation. Expert radiation oncologists are discussing how to implement AI rigorously, equitably, and without losing the human element of medicine.
2026-09
International Atomic Energy Agency (IAEA)
Artificial Intelligence Improves Collection of Global Radiotherapy Data
The IAEA's global radiotherapy database, DIRAC, has integrated AI into its workflow to enhance data collection and support research on access to cancer care. This new process uses AI to identify and convert publicly available information on radiotherapy centers and equipment into structured records, which are then validated by experts.
2026-06
GE HealthCare
GE HealthCare Expands Research Collaboration to Explore Using Generative AI for More Personalized Radiation Therapy
GE HealthCare announced a new collaboration with Mass General Brigham to explore how generative AI could help radiation oncology teams quickly access and interpret patient information for personalized cancer treatment. The goal is to develop an AI tool integrated into GE HealthCare's Intelligent Radiation Therapy (iRT) solution.
2026-09
Aidoc
RadOncAI | Informai radiology AI profile
RadOncAI provides AI-guided dose prediction from CT simulation and clinician-defined treatment-planning structures for adult head-and-neck malignant or benign disease. The software's output must be reviewed, revised, and approved by a radiation oncologist, medical physicist, or dosimetrist.
2026-09
EINPresswire.com
InformAI, Inc. Begins Phase 2 Work on NIH Grant for Innovative AI Solution, TransplantAI
InformAI, Inc. has begun Phase 2 work on a $2.2 million NIH Fast-Track grant to support TransplantAI, an AI solution addressing organ scarcity and allocation inefficiency. The grant will fund the development of more precise predictive models for heart and lung transplant outcomes.
2025-12
InformAI
XGBoost Outperforms Traditional Transplant Regulatory Models Based on Regression
A publication by Pettit, R. W., et al. (2026) highlights that XGBoost outperforms traditional transplant regulatory models based on regression. This research is featured on InformAI's website, indicating their involvement in advanced AI models for healthcare.
2026

Frequently Asked Questions

Informai's RadOncAI product aims to enhance precision and efficiency in radiation oncology by leveraging AI for tasks such as treatment planning, contouring, and patient outcome prediction. It is designed to integrate with standard DICOM-compliant imaging systems and existing oncology information systems to minimize disruption to current clinical workflows.
RadOncAI.net serves as a collaborative platform for advancing AI in radiation oncology, enabling researchers and clinicians to share insights and potentially de-identified data. The network prioritizes patient data privacy through robust anonymization protocols and strict adherence to international data protection regulations such as HIPAA and GDPR, ensuring secure and ethical data exchange.
Informai employs rigorous validation methodologies for its AI-driven software, including extensive retrospective and prospective studies to demonstrate clinical efficacy and safety. For patient outcome prediction and transplant decision support, the company collaborates with leading medical institutions to validate algorithms against real-world patient data and clinical endpoints.
Informai offers flexible pricing models for RadOncAI, which can include subscription-based licensing or per-use fees, tailored to the needs of individual healthcare providers. Comprehensive support services are provided, encompassing initial implementation and staff training, dedicated technical assistance, and continuous software updates and maintenance to ensure optimal performance.
Informai has forged strategic partnerships with key medical technology companies and prominent research institutions to enhance its AI capabilities and expand its reach. These collaborations foster innovation, facilitate the integration of RadOncAI with diverse healthcare platforms, and contribute to the company's long-term stability and competitive advantage in the market.
Informai addresses the 'black box' concern by developing AI models that prioritize interpretability and transparency, especially in critical applications like CT diagnostics and radiation dose planning. The company provides tools and interfaces that allow clinicians to understand the rationale behind AI-generated recommendations, fostering trust and enabling informed clinical decisions.
Informai's long-term vision for RadOncAI and RadOncAI.net is to establish a leading global ecosystem for AI-driven solutions in radiation oncology, continuously advancing treatment precision and patient outcomes. The company also explores strategic expansion into other medical imaging and diagnostic areas, leveraging its core AI expertise to address broader clinical needs and improve healthcare delivery.

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