Products

Ligence Heart
Ligence
Cardiology AI
Ligence Heart is an AI-powered web-based platform that automates the analysis and reporting of 2D transthoracic echocardiography, enhancing diagnostic efficiency and accuracy for cardiologists and sonographers.

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About Ligence

Ligence is a Lithuanian health-tech innovator specializing in AI-powered software for cardiac echocardiography, designed to transform how heart ultrasound exams are performed. Their flagship product, Ligence Heart, automates the complex and time-consuming processes of 2D transthoracic echocardiography (TTE) image analysis, measurements, and report generation. This innovative solution empowers cardiologists to achieve faster, more accurate, and consistent clinical decisions by significantly reducing the manual workload, which traditionally consumes a substantial portion of examination time. By streamlining these repetitive tasks, Ligence Heart allows clinicians to dedicate more valuable time to direct patient care and critical diagnostic interpretation.

The Ligence Heart platform is engineered for seamless integration into existing hospital IT infrastructures, including PACS, and adheres to international clinical guidelines such as ASE and ESC standards, ensuring reliable and reproducible cardiac measurements. Its user-friendly, vendor-neutral interface facilitates easy adoption and provides clinicians with transparent, guideline-based data for confident decision-making, particularly in follow-up care. The software has achieved significant regulatory milestones, including U.S. FDA 510(k) clearance in November 2025 and CE mark, validating its scientific credibility and readiness for broad clinical application. With ongoing clinical trials in key international markets and deployments across Europe, Ligence is committed to enhancing the accessibility, accuracy, and efficiency of cardiac ultrasound diagnostics globally.

Focus Areas

Echocardiography analysis cardiac ultrasound heart disease diagnostics AI-powered automation medical imaging workflow efficiency reporting cardiovascular disease

Business Intelligence

Key InvestorsSimpact Ventures, Coinvest Capital, European Innovation Council (EIC) Fund, Lemonade Stand, NGL Ventures (9NGLS), Rita Sakus
PartnershipsClinical trials in United States, Germany, Netherlands, Poland, Lithuania, Morocco; Research with Dr. Haotian Gu at King's College London; EIC Scaling Club; Collaboration with a major ultrasound manufacturer
AcquisitionsNone
TechnologyAI-powered software, web-based, integrates with PACS (Picture Archiving and Communication Systems), EHR (Electronic Health Records), CIS (Clinical Information Systems), RIS (Radiological Information Systems), processes DICOM format data, deep learning neural networks
FDA Clearances2 cleared products (estimated)

What Physicians Need to Know

Echocardiography Analysis Automation
Ligence Heart automates 2D Transthoracic Echocardiography (TTE) analysis and reporting, significantly streamlining the workflow for cardiac ultrasound examinations.
AI-Powered Diagnostics
The platform leverages advanced AI and deep learning to automate image evaluation, including view classification, heart phase prediction, segmentation, and landmark detection, improving diagnostic efficiency and accuracy for various heart diseases like heart failure, aortic stenosis, and pulmonary hypertension.
Workflow Efficiency & Reporting
Ligence Heart cuts echo reporting time in half and reduces the manual workload, allowing cardiologists to focus more on patient care. It generates detailed, guideline-based reports (EACVI, BSE, ASE) in local languages.
Cardiac Ultrasound & Heart Disease
Specializes in intelligent heart ultrasound image analysis for adult patients, aiding in the diagnosis and monitoring of conditions such as systolic dysfunction, pulmonary hypertension, heart failure, aortic stenosis, amyloidosis, and valvular heart diseases.
Left Ventricular Strain Analysis
Ligence has secured FDA 510(k) clearance for its fully automated Left Ventricular Strain analysis, further enhancing its diagnostic capabilities.
Physician Tip

Ligence Heart offers significant advantages for physicians by dramatically reducing the time spent on manual measurements and reporting, potentially saving up to 15 minutes per patient. This efficiency allows for increased patient throughput or more dedicated time for each patient, ultimately enhancing the quality of care. The AI-driven analysis provides consistent, precise, and reliable measurements, reducing inter- and intra-observer variability, which is crucial for accurate diagnosis and effective follow-up care. Its transparent, guideline-based approach (ASE, ESC, EACVI, BSE) ensures that clinicians have full visibility and confidence in the results, moving beyond 'black-box' solutions. The intuitive, web-based interface is designed to be easy to learn and use, resembling familiar programs, and the measurements are fully adjustable by the physician. Furthermore, Ligence's commitment to regulatory compliance (FDA Cleared & CE-Marked) and its development in collaboration with cardiologists ensure a trustworthy and clinically relevant tool.

Ligence Heart is designed for seamless integration with existing hospital systems. It is vendor-neutral and can integrate with PACS (Picture Archiving and Communication Systems), EHR (Electronic Health Records), cloud environments, and physical servers. The company also offers personalized solutions and APIs to work with unique or in-house developed systems, ensuring broad compatibility within complex healthcare IT infrastructures.

Products by Ligence

1 product in the directory

Ligence Heart
Ligence
Cardiology AI
Ligence Heart is an AI-powered web-based platform that automates the analysis and reporting of 2D transthoracic echocardiography, enhancing diagnostic efficiency and accuracy for cardiologists and sonographers.

What the Web Says

Ligence is a company founded in 2019 and headquartered in Vilnius, Lithuania, that specializes in AI-powered echocardiography analysis and reporting software called Ligence Heart. This software aims to automate the evaluation of heart ultrasound images, improving accuracy and efficiency in cardiac diagnostics. Reviews suggest that Ligence Heart significantly streamlines echocardiography workflows, saves time for cardiologists, and enhances diagnostic precision. The company emphasizes its software's intuitive interface, seamless integration with existing PACS and EHR systems, and adherence to various clinical guidelines.

Overall: Positive

Strengths

  • Significantly streamlines echocardiography workflow.
  • Offers significant time savings in daily clinical practice for cardiologists.
  • Improves diagnostic accuracy.
  • Automates evaluation of heart ultrasound images with non-inferior accuracy compared to cardiologists.
  • Reduces intra-rater variability of measurements.
  • Integrates seamlessly with existing PACS and EHR systems.

Limitations

  • No specific cons were found in the provided search results from G2, Glassdoor, Capterra, healthcare IT reviewers, or Reddit for Ligence.
  • The Elion profile for Ligence Heart is unclaimed, which might indicate less active engagement on that platform.

Based on reviews from: Elion, Ligence Official Website

Last updated: 2026-07-19

Videos

News, demos, and interviews about Ligence.

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Press & Coverage

Ligence
Ligence secures second FDA 510(k) clearance, adding fully automated Left Ventricular Strain analysis
Ligence announced its second U.S. FDA 510(k) clearance for Ligence Heart, its AI-powered echocardiography software, now featuring fully automated Left Ventricular Global Longitudinal Strain (LV GLS) analysis and private cloud deployment options. This expands the platform's capabilities for cardiac ultrasound analysis.
2026-04
LSMU
Successful U.S. Market Entry by Lithuanian Medical Startup: Solution that Redefines Routine Clinical Practice is the Key
Ligence received FDA 510(k) approval for its AI-based cardiac ultrasound software, Ligence Heart, marking one of the first such approvals in Central, Northern, and Eastern Europe for automating heart ultrasound research. This clearance allows U.S. healthcare institutions to use Ligence Heart for automated heart measurement analysis and structured reporting.
2026-01
Disruptivity Times
Ligence Heart Deploys Universal AI Copilot for Echocardiography | Disruptivity Times
Ligence Heart has launched its universal AI copilot for echocardiography, integrating with major cardiac ultrasound machines in Europe through direct API agreements with GE Healthcare, Philips, and Siemens Healthineers. This deployment aims to embed automated image analysis as a baseline standard, reducing measurement time and inter-operator variability.
unknown
Ligence
Ligence Heart receives FDA 510(k) clearance
Ligence announced that its AI-powered echocardiography software, Ligence Heart, has received U.S. Food and Drug Administration (FDA) 510(k) clearance. This enables U.S. healthcare providers to use the software for automated measurements and analysis of 2D transthoracic echocardiography images, aiming to reduce workload and improve workflow efficiency.
2025-11
EIC Scaling Club
Ligence: Bringing AI innovation to the heart of cardiac diagnostics - EIC Scaling Club
Ligence has achieved significant milestones, including becoming the first ultrasound AI to receive the new CE mark and demonstrating that its fully automated Ligence Heart outperformed human measurements in a landmark study. The company is expanding into the U.S. market with further international growth planned for 2026.
2025-11
Ligence
AI4CMR and Ligence announce a Strategic Partnership
AI4CMR and Ligence have formed a strategic partnership to enhance cardiology diagnostics through AI, combining their solutions for cardiac MRI and echocardiography. This collaboration aims to streamline workflows, improve diagnostic precision, and reduce reporting times in clinical environments.
2025-07
EIT Regional Innovation Scheme
AI in Healthcare: Ligence Secures u20ac6M for Cardiac Ultrasound Automation
Ligence, a Lithuanian health-tech startup, secured u20ac6 million in funding to advance its AI-driven cardiac ultrasound analysis technology. This investment aims to automate echocardiography, reduce cardiologists' manual workload, and improve diagnostic efficiency and patient care.
2024-12
ArcticStartup
Lithuanian startup gains u20ac3M to expand AI-driven echocardiography solution across global markets - ArcticStartup
Ligence, a Vilnius-based startup, secured u20ac3 million in seed funding led by Simpact Ventures, with contributions from Coinvest Capital, the European Innovation Council (EIC) Fund, and others. This funding will support the expansion of its AI-powered software for automating cardiac ultrasound image analysis.
2024-11

Frequently Asked Questions

Ligence Heart is an AI-powered software designed for automated analysis and reporting of 2D transthoracic echocardiography (TTE) studies. It streamlines the diagnostic process by automatically segmenting cardiac structures, performing measurements, and detecting pathologies like heart failure, pulmonary hypertension, and systolic dysfunction. This automation reduces manual workload, enhances diagnostic accuracy and consistency, and allows clinicians to focus more on patient care.
Ligence Heart is a web-based, fully integrated echocardiography analysis suite that seamlessly integrates with existing hospital systems, including PACS and EHR. It captures images from ultrasound machines, automatically annotates them, and generates reports, significantly cutting down on the time cardiologists and sonographers spend on manual measurements and reporting. This integration aims to reduce scan times and improve overall workflow efficiency in echo labs.
Ligence Heart assists in the diagnosis and monitoring of various cardiovascular conditions, including systolic dysfunction, pulmonary hypertension, and heart failure. It provides detailed analysis of cardiac parameters, aiding in the assessment of conditions like coronary artery disease, valvular disorders, and cardiomyopathies. The software's consistent measurements are particularly valuable for tracking disease progression and treatment response over time.
Ligence Heart is CE-Marked, classifying it as a Class IIa medical device under the European Commission's MDR 2017/745 framework. Additionally, it has received FDA 510(k) clearance in the United States, enabling its use by healthcare providers in the U.S. for automated and manual analysis of adult 2D TTE images and reporting.
While specific pricing details require direct vendor contact, Ligence Heart is generally offered with a one-time license fee based on the number of installations. Ligence provides comprehensive customer support, including dedicated customer service contact channels ([email protected]) and readily available user manuals and release notes for their software.
Ligence has established strategic partnerships to broaden its market reach and enhance its offerings. Notable collaborations include Blackford, an imaging AI platform provider, to make Ligence Heart available on their platform, and HealthCare Konnect for distribution in Switzerland and North Africa. They also partner with AI4CMR to deliver a combined multimodality solution for cardiac imaging.
Founded in 2019 in Lithuania, Ligence is a health-tech startup focused on AI-driven cardiac ultrasound analysis. The company has demonstrated financial stability by securing significant funding, including u20ac6 million in total funding, with a u20ac3 million seed round led by Simpact Ventures and a convertible loan from the European Innovation Council Fund. They are actively expanding globally, indicating a strong growth trajectory.

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