Perimeter Medical Imaging AI

Toronto, Canada; Dallas, Texas, USA  All Canada companies → Founded 2013
Imaging AI Specialist Medical Device / Hardware Specialty-Focused AI
General Surgery Pathology
Oncology AI Pathology AI Surgical AI
Public — Approximately $9.86M CAD (Sept 2024 private placement), C$3.6 Million (Dec 2025 private placement), $7.4M USD grant from Cancer Prevention and Research Institute of Texas (CPRIT)

Products

OTIS 2.1 Optical Coherence Tomography
Perimeter Medical Imaging AI, Inc.
Oncology AI
The OTIS 2.1 Optical Coherence Tomography System by Perimeter Medical Imaging AI is an FDA-cleared imaging tool for real-time, high-resolution visualization and analysis of excised human tissue microstructure, aiding in the identification of regions of interest during surgical procedures.

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About Perimeter Medical Imaging AI

Perimeter Medical Imaging AI is a medical technology company dedicated to transforming cancer surgery through the application of ultra-high-resolution, real-time imaging tools, with a primary focus on improving intraoperative margin assessment. The company’s core technology leverages Optical Coherence Tomography (OCT) to provide surgeons with high-definition, 3D images of excised tissue margins at a cellular level, offering 10 times higher resolution than traditional X-ray and ultrasound at a 2mm imaging depth. This aims to provide immediate clarity in the operating room, potentially reducing the need for repeat surgeries due to positive margins.

Perimeter offers the FDA-cleared S-Series OCT system, which provides real-time, cross-sectional visualization of excised tissues. Furthermore, their next-generation investigational technology, the Perimeter B-Series OCT with ImgAssist AI (now known as Claire™), has received U.S. FDA Breakthrough Device Designation and recently obtained FDA premarket approval as the first AI-enabled imaging device approved in the United States for intraoperative breast cancer margin assessment. This AI-powered system is designed to enhance surgeons’ ability to detect difficult-to-see cancer during breast-conserving surgery, with the goal of lowering re-excision rates and improving patient outcomes.

Focus Areas

Intraoperative margin assessment breast cancer surgery Optical Coherence Tomography (OCT) Artificial Intelligence (AI) real-time imaging surgical oncology reducing re-excision rates

Business Intelligence

Key InvestorsChamath Palihapitiya (Social Capital), Rocco Schiralli, Cancer Prevention and Research Institute of Texas (CPRIT)
PartnershipsIntermountain Health, Jennifer Douglas (patient advocate), Covenant Health Fort Sanders Regional, CHRISTUS St. Vincent, NVIDIA Connect Program, West Cancer Center & Research Institute, Baylor College of Medicine, Methodist Healthcare, MD Anderson Cancer Center at Cooper, University of Wisconsin, Moffitt Cancer Center, Medical City Healthcare, Baptist MD Anderson Cancer Center, Mayo Clinic, University of Washington/Fred Hutchinson Cancer Center
TechnologyProprietary Optical Coherence Tomography (OCT) technology, wide-field OCT, AI-enabled image analysis, machine learning algorithms, proprietary dataset of over 2 million breast tissue images
FDA Clearances2 cleared products (estimated)

What Physicians Need to Know

Specialization: Intraoperative Margin Visualization
Perimeter Medical Imaging AI specializes in providing ultra-high-resolution, real-time imaging of excised tissue specimens during cancer surgery, primarily focusing on breast cancer margin assessment.
Key Differentiator: First FDA-Approved AI for Breast Cancer Surgery
Their Claireu2122 system (formerly Perimeter OCT B-Series with ImgAssist AI 2.0) is the first AI-enabled imaging device approved by the U.S. FDA for intraoperative breast cancer margin assessment.
Technology Stack: Optical Coherence Tomography (OCT) & AI
The core technology is Optical Coherence Tomography (OCT), which provides 3D, cellular-level imaging with 10x higher resolution than X-ray and ultrasound. This is coupled with proprietary AI and machine learning algorithms (ImgAssist AI/Claire) trained on millions of breast tissue images to assist in identifying suspicious areas.
Physician Benefit: Real-time Surgical Decision Support
The technology offers immediate, actionable insights on margin status directly in the operating room, aiming to reduce the uncertainty surgeons face and potentially decrease re-excision rates for patients.
Physician Benefit: Enhanced Precision & Efficiency
Perimeter's systems streamline the diagnostic process by rapidly analyzing images and highlighting areas requiring closer examination, improving diagnostic accuracy and overall efficiency in patient care.
Impact: Improved Patient Outcomes
By enabling faster diagnosis, more accurate treatment planning, and a reduction in the need for repeat surgeries, the technology aims to improve long-term outcomes and reduce the emotional and physical trauma for cancer patients.
Physician Tip

For physicians considering or utilizing Perimeter Medical Imaging AI's tools, leverage the real-time, high-resolution OCT imaging and AI-powered insights to make more informed intraoperative decisions regarding surgical margins. This can significantly enhance your confidence in achieving clean margins during the initial surgery, potentially reducing patient re-excisions and improving overall patient experience and outcomes. Integrate the system into your existing OR workflow as an adjunctive tool to complement traditional pathology, providing immediate clarity at the point of care. Actively participate in data registries, if applicable, to contribute to the continuous improvement of AI algorithms and advance cancer care.

Perimeter Medical Imaging AI's S-Series OCT system is designed to fit readily into existing surgical workflows and is portable for use in various operating rooms. The company has also established systemwide agreements with healthcare providers, such as Intermountain Health, to facilitate the deployment and integration of their advanced imaging technology across multiple hospitals. Their technology does not replace pathology but provides essential real-time insight to aid surgeons.

Products by Perimeter Medical Imaging AI

1 product in the directory

OTIS 2.1 Optical Coherence Tomography
Perimeter Medical Imaging AI, Inc.
Oncology AI
The OTIS 2.1 Optical Coherence Tomography System by Perimeter Medical Imaging AI is an FDA-cleared imaging tool for real-time, high-resolution visualization and analysis of excised human tissue microstructure, aiding in the identification of regions of interest during surgical procedures.

What the Web Says

Perimeter Medical Imaging AI receives mixed to positive reviews, primarily focusing on its innovative AI-powered imaging technology for cancer surgery. Product reviews highlight the potential for improved surgical outcomes and real-time margin assessment, while employer reviews touch upon aspects like company culture and growth opportunities.

Overall: Mixed

Strengths

  • Innovative AI technology for real-time margin assessment in cancer surgery
  • Potential to improve surgical accuracy and reduce re-excision rates
  • Positive impact on patient care and outcomes
  • Cutting-edge technology in the medical imaging field
  • Collaborative work environment (mentioned in some employer reviews)
  • Growth opportunities within a developing company

Limitations

  • Relatively new technology, so long-term impact and widespread adoption are still evolving
  • Limited number of extensive product reviews available from major platforms like G2 or Capterra specifically for the product itself
  • Some employer reviews mention challenges common to growing companies, such as workload or evolving processes
  • Specific pricing and implementation details are not widely available in public reviews
  • As a specialized medical device, direct comparisons and user reviews are less frequent than for general software
  • Information on specific customer support experiences is not broadly detailed in public forums

Based on reviews from: Glassdoor, Reddit, Healthcare IT News (various articles/mentions), Company press releases and investor relations, Medical technology news outlets

Last updated: 2026-07-20

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Frequently Asked Questions

Perimeter Medical Imaging AI offers the S-Series OCT system, an FDA-cleared device providing real-time, ultra-high-resolution 3D imaging of excised tissue microstructure during surgery. Their flagship product, Claireu2122 (formerly B-Series OCT with ImgAssist AI), is the first FDA-approved AI-enabled imaging device for intraoperative breast cancer margin assessment, designed to help surgeons detect difficult-to-see cancer and potentially reduce re-operations.
Perimeter's S-Series OCT system has received 510(k) clearance from the U.S. FDA for imaging excised human tissue microstructure. Their AI-enabled device, Claireu2122, received U.S. FDA Premarket Approval (PMA) and Breakthrough Device designation, making it the first AI-enabled imaging device approved for intraoperative breast cancer margin assessment. The company adheres to general controls provisions of the Act, including requirements for annual registration, device listing, good manufacturing practice, and labeling.
Perimeter Medical Imaging AI often utilizes a 'Managed Solution' pricing model, which involves placing the S-Series OCT device at no charge and then charging a per-procedure fee for Specimen Immobilizer consumables. This approach aims to smooth out revenue streams for hospitals and avoid lengthy capital equipment approval processes. For Claire, given its premium positioning and Breakthrough Device designation, there is potential for faster reimbursement pathways, such as New Technology APC levels, which would be in addition to existing lumpectomy procedure payments.
Perimeter Medical Imaging AI offers a 'white-glove' support experience, including a no-charge evaluation period and clinical support tailored to specific needs. They provide image interpretation training, an exclusive Imaging Atlas with pathology-verified tissue structure correlations, and in-OR support from their field-based Clinical Education team to ensure efficient adoption and expertise.
Yes, Perimeter Medical Imaging AI actively partners with leading breast surgeons and cancer centers for clinical trials and development. They have established systemwide agreements with healthcare systems like Intermountain Health and HCA HealthONE to deploy their technology and evaluate its value.
Perimeter Medical Imaging AI is a commercial-stage medical technology company with a growing installed base of its S-Series OCT system, contributing to increased revenues. While currently unprofitable, the company has seen significant revenue growth and has recently completed a private placement to strengthen its balance sheet and support commercialization efforts, particularly for the newly FDA-approved Claire system.

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