Polso (formerly ChroniSense Medical)

Boston, Massachusetts, USA and Yokneam Illit, Israel  All Israel companies → Founded 2015
Patient Engagement Platform Wearables / RPM
Family Medicine Physical Medicine & Rehab Sports Medicine
Grant — Undisclosed

About Polso (formerly ChroniSense Medical)

Polso, formerly ChroniSense Medical, is a digital health company focused on transforming remote patient care and advancing clinical research. Their core offering is a remote patient monitoring (RPM) platform that combines a medical-grade, wrist-worn multi-sensor device with a patient mobile application and a cloud-based clinician dashboard. This system is designed to continuously monitor multiple vital signs, including pulse rate, blood oxygen level, respiratory rate, and blood pressure, with clinically validated accuracy. The platform emphasizes signal processing and data science to deliver medical-grade monitoring for chronic disease management and supports clinical validation and decentralized clinical trials.

For physicians, Polso’s solution aims to empower patients with a better understanding of their biometric data while providing healthcare providers and clinical researchers with easy, remote access to multiple vital signs, ultimately improving patient care and outcomes. The company’s technology has achieved regulatory clearance for selected vital-sign measurements, with initial FDA 510(k) clearance for monitoring blood oxygen saturation (SpO2), pulse rate, and respiration rate. They are also developing additional vital sign monitoring parameters, including blood pressure via IP-protected radial artery signal acquisition. Polso’s platform is built to lay the foundation for future AI-based predictive insights.

Focus Areas

Remote Patient Monitoring (RPM) Chronic Care Management Decentralized Clinical Trials (DCT) Wearable Medical Devices Vital Sign Monitoring Digital Health Signal Processing Biosignal Analytics AI/ML Predictive Analytics (development)

Business Intelligence

Key InvestorsRainbow Medical, Vinno Capital
PartnershipsMilton Keynes University Hospital (for a clinical validation study)
TechnologyPolso CONNECT™ is a multi-sensor wireless wrist monitor, mobile application, and cloud-based platform. It leverages robust radial artery signals for medical-grade vital sign acquisition and is building the foundation for future AI-based predictive insights.
FDA Clearances1 cleared products (estimated)

What Physicians Need to Know

Specialization
Polso (formerly ChroniSense Medical) specializes in advanced Remote Patient Monitoring (RPM) for chronic disease management and Decentralized Clinical Trials (DCTs). Their platform, Polso CONNECTu2122, provides medical-grade, multi-vital sign monitoring.
Key Differentiators
Polso's key differentiators include their world-class signal processing and data science capabilities, enabling robust biosignal acquisition from the radial artery for a full range of medical-grade parameters. They offer a multi-sensor wireless wrist monitor, a mobile application for patients, and a cloud-based platform for clinicians. The Polsou2122 Watch has received FDA 510(k) clearance for monitoring blood oxygen saturation (SpO2), pulse rate, and respiration rate.
Technology Stack
Their technology stack includes a wearable multi-sensor hardware device (Polsou2122 Watch) with integrated sensors for ECG, PPG, accelerometer, and temperature. The system utilizes Bluetooth for communication with a companion mobile application (Polsou2122 App) on Android devices, and a cloud-based platform for clinicians. They are also building the foundation for future AI-based predictive insights.
Future Developments
Polso is actively developing additional vital sign monitoring parameters, including blood pressure via IP-protected radial artery signal acquisition. They are also exploring blockchain technology for a 'move and earn' model, integrating physical activity with cryptocurrency, though this appears to be a separate initiative from their core medical device offering.
Physician Tip

For physicians, Polso offers a reliable and easy-to-use remote patient monitoring solution for chronic care management and decentralized clinical trials. The medical-grade data, derived from robust radial artery biosignals, provides trustworthy insights into patient health. The platform's ability to monitor multiple vital signs through a comfortable wrist-worn device can enhance patient compliance and engagement. The cloud-based platform allows for remote review of patient data, facilitating proactive care and potentially reducing healthcare costs associated with chronic conditions. The ongoing development of additional parameters like blood pressure monitoring further expands its potential utility in managing complex patients.

While the core Polso CONNECTu2122 platform integrates a wearable device, mobile app, and cloud platform, specific information regarding integrations with existing Electronic Health Record (EHR) systems or other healthcare IT infrastructure is not explicitly detailed in the provided information. However, their expertise in digital health platform development (mobile + cloud) and regulatory submissions suggests a capability for such integrations.

Products by Polso (formerly ChroniSense Medical)

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Press & Coverage

PR Newswire
Promising Remote Patient Monitoring solution, Polsou2122, Achieves 1st FDA Clearance
ChroniSense Medical Ltd. announced that its Polsou2122 Remote Patient Monitoring (RPM) solution received 510(k) clearance from the U.S. Food and Drug Administration (FDA) for monitoring blood oxygen saturation (SpO2), pulse rate, and respiration rate. This clearance is a significant step towards commercializing Polso CONNECTu2122 for chronic care management.
2022-12
Medical Product Outsourcing
FDA Clears ChroniSense's Polso Watch for Remote Monitoring
ChroniSense Medical obtained FDA 510(k) clearance for its Polso remote patient monitoring solution, which monitors blood oxygen saturation, pulse rate, and respiration rate. The Polso device combines a wrist-worn vital signs monitor with a mobile app and cloud platform for clinicians.
2022-12
Medical Design & Development
Polso Remote Patient Monitoring Device Approved by FDA
ChroniSense Medical's Polso, a Remote Patient Monitoring (RPM) solution, has received 510(k) clearance from the FDA for monitoring blood oxygen saturation, pulse rate, and respiration rate. The device aims to transform chronic care management by providing an easy-to-use, medical-grade solution.
2022-12
NoCamels
Smartwatch Monitors Patients' Vital Signs
Israeli medtech company ChroniSense Medical developed Polso, a smartwatch that functions as a wearable medical sensor to accurately monitor vital signs. The device, designed for home and clinical use, recently received FDA clearance.
2022-12
Journal of Medical Internet Research
ChroniSense National Early Warning Score Study: Comparison Study of a Wearable Wrist Device to Measure Vital Signs in Patients Who Are Hospitalized
This study evaluated the clinical validity of the ChroniSense Polsou2122 wearable wrist device for measuring vital signs and providing National Early Warning Scores in hospitalized patients. The research compared wearable device measurements to standard nurse-led manual measurements.
2023-02
BMJ Open / PMC
ChroniSense National Early Warning Score Study (CHESS): a wearable wrist device to measure vital signs in hospitalised patientsu2014protocol and study design
This protocol outlines the ChroniSense National Early Warning Score Study (CHESS), which aims to evaluate the clinical validity of the Polso wrist-based device for providing National Early Warning Scores in hospitalized patients. The study compares Polso measurements to current manual methods.
2019-09
Polso (ChroniSense Medical)
ChroniSense in the News: Forbes Article on Remote Patient Monitoring
ChroniSense Medical was featured in a Forbes article, offering commentary on trends in remote patient monitoring (RPM) and highlighting the role of its Polsou2122 device in transforming healthcare delivery. The article discussed the evolving landscape of RPM, including reimbursement and device-sourced data.
2020-01
Polso (ChroniSense Medical)
Healthcare Transformation Executive Dr. Liz Kwo Joins the ChroniSense Medical Board of Directors
ChroniSense Medical welcomed Dr. Liz Kwo, a healthcare transformation executive, to its Board of Directors as the company's first independent board director. Dr. Kwo brings extensive clinical, entrepreneurial, and leadership experience to the board.
2022-05

Frequently Asked Questions

Polso offers the Polso CONNECTu2122 remote patient monitoring platform, which includes a wrist-worn, multi-sensor vital sign monitor, a patient mobile application, and a cloud-based clinician platform. This system is designed for continuous, medical-grade monitoring of vital signs for chronic disease management and supports decentralized clinical trials.
Polso's remote patient monitoring solution, Polsou2122, received U.S. FDA 510(k) clearance in December 2022 for monitoring blood oxygen saturation (SpO2), pulse rate, and respiration rate. The company emphasizes medical-grade monitoring and adherence to relevant international standards for medical devices, including biocompatibility testing per ISO 10993, software V&V per IEC 62304, and electrical safety per IEC 60601.
While specific pricing structures are not publicly detailed, Polso aims to address the significant healthcare costs associated with chronic conditions, which exceed $1.1 trillion annually in the US. Their solution is designed to provide an easy-to-use, medical-grade remote patient monitoring system, suggesting a focus on cost-effectiveness through improved chronic care management.
Polso provides a remote patient monitoring solution delivery, which includes the deployment of their wearable vital-sign monitoring system with a patient mobile app and clinician cloud platform. They also offer support for clinical validation studies and integration into decentralized clinical trial workflows.
Polso (ChroniSense Medical) is a portfolio company of Rainbow Medical and continues its clinical development in collaboration with leading hospitals, partners, and expert practitioners in the U.S. and globally. They have also been involved in studies like the CHroniSense National Early Warning Score Study (CHESS) at Milton Keynes University Hospital.
ChroniSense Medical rebranded to Polso, signifying a focus on transforming chronic care management through their advanced remote patient monitoring platform. The company has secured FDA clearance for its Polso device, a significant milestone for commercialization and creating a new model in chronic care management. Their leadership team has decades of industry experience, and they are committed to developing innovative medical devices.

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