Products

Relu Creator
Relu BV
Dental AI
Relu® Creator is an AI-powered dental software for automated CBCT segmentation, 3D modeling, and treatment planning, designed to enhance efficiency and precision in dental clinics and labs.

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About Relu BV

Relu BV is a healthcare AI company specializing in automating digital dentistry workflows for dental laboratories and clinicians. Their AI-powered platform, Relu® Automate, is designed to streamline and enhance various aspects of dental treatment planning and design. This includes automating the design and administrative tasks for common dental cases such as night guards, crowns, and dental models. The company’s technology also focuses on advanced 3D imaging software, including CBCT segmentation for implant, surgical, and orthodontic workflows. Relu’s solutions aim to address the growing shortage of skilled dental technicians by significantly reducing manual design time, allowing labs to increase their output and efficiency without compromising quality.

For physicians, Relu’s offerings translate to faster and more consistent dental designs, empowering dental professionals to redefine patient care. The Relu® Engine and Relu® Creator are utilized by dental labs and software partners for thousands of orthodontic and implant treatments daily. Their AI algorithms are integrated into popular dental treatment planning software, optimizing treatment planning and simulation, streamlining patient communication, and enhancing research, education, and training. Relu’s technology is backed by multiple medical research studies, has achieved CE marking (under the EU MDR) and FDA 510(k) clearance for Relu® Creator, and ISO13485 certification, ensuring adherence to stringent European and US product standards for safety and performance.

Focus Areas

AI-powered dental design digital dental treatment planning automated segmentation orthodontics implantology crown & bridge custom trays bleaching trays virtual patient creation surgical guide design

Business Intelligence

TechnologyAI algorithms, computer vision, deep learning, 3D-Unet networks, cloud-native (Relu® Cloud), REST API (Relu® Hosted Engine), SDK integration. Products: Relu® Creator, Relu® Engine, Relu® Automate.

What Physicians Need to Know

AI-Powered Dental Design & Planning
Relu BV specializes in using AI to automate and enhance various aspects of dental design and treatment planning, including orthodontics, implantology, crown & bridge, custom trays, bleaching trays, virtual patient creation, and surgical guide design. They automate over 50,000 dental designs monthly in the USA and Europe.
Automated Segmentation
A core specialization is automated CBCT segmentation of single teeth, mandibles, full skulls, and critical anatomy like mandibular canals and maxillary sinuses. This was a pioneering effort in 2019, long before AI became a widespread trend in dentistry.
Virtual Patient Creation
Relu has achieved a breakthrough with the creation of the CE-certified virtual patient, integrating CBCT data with intraoral scans to produce clinically accurate 3D models that eliminate crown artifacts. This allows for comprehensive treatment planning, including roots, crowns, and bone.
Implant Planning & Surgical Guides
They offer automated, crown-driven implant planning and surgical guide design, which is CE-certified and clinically validated. This includes automatic nerve and sinus detection for safer outcomes and seamless integration into restorative-driven workflows.
Restorative Dentistry
Relu's AI supports the design of crowns, bridges, custom trays, bleaching trays, and dental models, aiming for highly automated workflows in restorative dentistry.
Orthodontics
Their technology is adopted by aligner and digital bonding companies for digital orthodontic planning with roots and bone at scale, helping to avoid root collisions and prevent roots from being moved outside the bone during treatment.
Key Differentiators
Relu's key differentiators include pioneering AI in dentistry since 2019, offering CE-certified and clinically validated solutions, and providing a cloud-based platform for instant, crown-driven implant proposals with automatic nerve and sinus detection. They also focus on automating a significant portion of dental designs (vision of 80% automation in the next decade).
Technology Stack
Their technology centers on AI-assisted dental CAD automation and CBCT segmentation. The company's name, 'Relu', is an abbreviation of Rectified Linear Unit, an activation function used in artificial neural networks, indicating their deep learning foundation.
Physician Tip

For physicians, Relu BV's technology offers faster, safer, and more predictable outcomes by automating time-consuming manual processes in treatment planning. The virtual patient creation provides a complete 3D picture for comprehensive planning, integrating roots, crowns, and bone. The AI-powered implant planning includes automatic nerve and sinus detection, enhancing safety and predictability. The cloud-based platform allows for instant treatment proposals and access from any device, reducing the need for heavy software or hardware investments. Relu's solutions are CE-certified and clinically validated, ensuring adherence to stringent standards.

Relu partners with leading dental software companies and dental labs to embed their AI planning and design automation into existing clinical workflows. They make their algorithms available through an API or SDK, allowing seamless integration into various treatment planning software. Relu's 'Single Inbox' automates the intake of scans and prescriptions from all major intraoral scanner brands, email, and cloud storage, standardizing incoming data for efficient workflow.

Products by Relu BV

1 product in the directory

Relu Creator
Relu BV
Dental AI
Relu® Creator is an AI-powered dental software for automated CBCT segmentation, 3D modeling, and treatment planning, designed to enhance efficiency and precision in dental clinics and labs.

What the Web Says

Relu BV appears to be a company with two distinct facets based on the search results: "Relu Consultancy" which focuses on AI automation and digital product development, and "Relu BV" which is involved in healthcare IT, specifically medical image management and viewing. Reviews for "Relu Consultancy" on G2 are overwhelmingly positive, highlighting their professionalism, responsiveness, and effective solutions. Information regarding "Relu BV" in the healthcare IT space is primarily from FDA approvals for products like Relu Cloud and Relu Creator, indicating their involvement in radiology and medical image processing. There were no specific product reviews for Relu BV's healthcare IT products on the platforms searched, nor were there employer reviews for Relu BV as a distinct entity from "ReluTech" or "Relu Consultancy".

Overall: Positive

Strengths

  • Professional and responsive team for AI automation and digital product development.
  • Fast turnaround time from talented developers.
  • Effective in building AI models and automating system workflows.
  • User-friendly interface provided by Relu Consultancy.
  • Delivers solutions tailored to specific organizational goals.
  • Good communication and affordable outputs from Relu Consultancy.

Limitations

  • One review for Relu Consultancy mentioned that the finished product took longer than expected.
  • Lack of specific product reviews for Relu BV's healthcare IT products.
  • Limited employer reviews directly for "Relu BV"; some negative employer reviews exist for a company called "ReluTech" which may or may not be related.

Based on reviews from: G2, FDA (via Innolitics and accessdata.fda.gov), Indeed.com (for ReluTech)

Last updated: 2026-10-25

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Press & Coverage

EU-Startups
Belgian AI dental startup Relu lands €1.51 million to accelerate US expansion
Relu, a Leuven-based AI startup focused on automating dental design and planning workflows, secured a €1.51 million strategic investment from Dental Innovation Alliance (DIA) to expand its presence in the US market. This funding follows a €2 million seed round in March 2023, also backed by DIA.
2026-08
Dealroom News
Relu raises $1.75M from repeat backer DIA to expand in the US
Relu, a Belgian AI startup automating dental lab design work, raised a $1.75 million strategic investment from Dental Innovation Alliance (DIA), a repeat investor. The capital will be used to strengthen Relu's position in the US market, addressing the shortage of skilled dental technicians.
2026-08
Relu (Press Release)
Relu Secures FDA 510(k) and CE Marking for Revolutionary Dental Software Relu® Creator
Relu announced it received both FDA 510(k) clearance and CE Mark approval for its Relu® Creator software, a dental tool that uses AI to create 3D anatomical models from patient scans. These regulatory milestones allow for commercial distribution in the US and EU.
2024-10
Dentistry Today
Relu Announces Single Inbox for Dental Labs
Relu launched 'Single Inbox,' a new feature that automates dental lab intake by centralizing and standardizing scans, prescriptions, and metadata from various sources. This aims to reduce manual work and improve efficiency for dental laboratories.
2026-09
Business Wire
Relu® Cloud Receives CE Certification for AI Implant Planning and Unlocks EU Market Access
Relu.ai received CE certification under the EU MDR for its AI automatic implant planning solution, Relu® Cloud. This certification allows Relu to offer its AI-powered implant planning and surgical guide design to dental professionals in the EU.
2025-10
DrBicuspid.com
Relu Creator gets FDA approval, CE Mark
Dental AI software provider Relu has received FDA 510(k) clearance and a CE Mark for its Relu Creator tool, which utilizes AI for automated anatomical identification and enhanced 3D imaging in dental procedures.
2024-10
The SaaS News
Relu Raises $1.75M Strategic Investment
Relu, a software company based in Belgium and Boston, secured a $1.75 million strategic investment from Dental Innovation Alliance (DIA) to accelerate the expansion of its AI-powered dental lab automation platform in the US.
2026-08
Relu (Press Release)
Relu Raises €2 Million Funding to Automate Dental Treatment Planning
Relu, a dental software company, raised €2 million in seed funding from global dental industry investors, including Dental Innovation Alliance, to advance its AI algorithms for automating digital dental treatment planning and expand its focus on EU and US markets.
2023-03

Frequently Asked Questions

Relu BV specializes in AI-powered automated segmentation for dental CBCT and intraoral scans, facilitating digital dental treatment planning across various specialties. Their solutions aim to streamline workflows for orthodontics, implantology, crown & bridge, custom trays, and bleaching trays by providing precise anatomical models and virtual patient creation. The integration is designed to be compatible with common dental CAD/CAM software and imaging systems, minimizing disruption to current clinical practices.
Relu BV prioritizes the accuracy and reliability of its AI algorithms through extensive validation against ground truth data and clinical expert review. Their AI models are trained on diverse datasets to ensure robust performance across various patient anatomies and imaging modalities, which is crucial for applications such as surgical guide design and implant planning. The company also emphasizes continuous improvement and rigorous testing to maintain high standards of precision and safety in their solutions.
Relu BV is committed to adhering to relevant medical device regulations and obtaining necessary certifications for its AI software. This includes compliance with regulations in major markets such as the EU (e.g., MDR) and the US (e.g., FDA clearance). The company focuses on demonstrating the safety and efficacy of its products through robust documentation and clinical validation to meet these stringent requirements.
Relu BV offers flexible pricing structures tailored to the needs of different practices and institutions. This typically includes subscription models for access to their AI platform, per-case fees for specific services like automated segmentation or surgical guide design, and enterprise licensing options for larger organizations. Specific details on pricing are usually provided after an initial consultation to understand the client's unique requirements and usage volume.
Relu BV provides comprehensive technical support and training programs to ensure seamless adoption and effective utilization of their AI dental solutions. This includes initial onboarding, user manuals, online resources, and dedicated customer support channels. Training can be customized to cover specific aspects of their software relevant to different clinical roles, helping staff to quickly become proficient in leveraging the AI tools for improved patient care.
Relu BV's long-term vision is to be a leading innovator in AI-powered dental solutions, continuously expanding their offerings and improving patient outcomes. The company's stability is underpinned by a strong focus on research and development, strategic investments, and a growing customer base. Relu BV actively pursues partnerships and collaborations with dental technology providers, academic institutions, and industry leaders to enhance their market position and drive future growth.
Relu BV's AI algorithms are designed to be robust and adaptable to variations in scan quality from a wide range of CBCT machines and intraoral scanners. While the AI can process diverse inputs, optimal results are achieved with scans that meet certain minimum quality requirements regarding resolution, contrast, and artifact reduction. Relu BV provides guidelines and recommendations for scan acquisition to help users achieve the best possible outcomes with their AI solutions.

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