Products

SafeBeat Rx App
SafeBeat Rx, Inc.
Cardiology AI
An AI application designed to support safe pharmacological treatment and monitoring for cardiac arrhythmias.

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About SafeBeat Rx

SafeBeat Rx is a healthcare AI company focused on transforming cardiac care by expanding access to remote patient monitoring (RPM), continuous telemetry, event monitoring, and software-enabled remote therapeutic monitoring (RTM). The company’s core offering is an integrated technology that utilizes automated artificial intelligence-based software to analyze electrocardiogram (ECG) data. This technology is designed to replace the traditional three-day hospitalization often required for cardiac monitoring when initiating certain antiarrhythmic medications, enabling arrhythmia patients to start these medications safely from home.

For physicians, SafeBeat Rx’s platform aims to streamline clinical workflows and enhance patient monitoring by providing explainable AI and custom tools that display diagnostic information and treatment steps tailored to the patient. The company’s proprietary machine learning algorithms are designed for ECG interpretation and treatment management recommendations, offering efficiency and streamlined insights. SafeBeat Rx’s technology is currently under development and limited to investigational use, with ongoing clinical trials, including one at the University of California, San Francisco (UCSF), to validate its algorithms and gather user feedback.

Focus Areas

cardiac care remote patient monitoring remote therapeutic monitoring ECG analysis artificial intelligence atrial fibrillation drug-induced QT prolongation digital health wearables

Business Intelligence

Key InvestorsY Combinator, Zillionize, HHS, HeartX Accelerator, Defense TechConnect, MedTech Innovator, LG Nova
PartnershipsUCSF (clinical trial collaboration), Zoll (manufacturer of LifeVest)
Technologycloud-native, AI-based software platform with proprietary machine learning algorithms for ECG interpretation and treatment management, integrated with third-party FDA-cleared cardiac monitoring devices (mobile ECG, mobile cardiac telemetry, implantable cardiac monitor)
FDA Clearances1 (SafeBeat Rx App, K251218) cleared products (estimated)

What Physicians Need to Know

Specialization in Cardiac Care
SafeBeat Rx focuses on cardiac care, particularly in managing atrial fibrillation (AFib) and drug-induced QT prolongation. They aim to expand access to life-saving heart medications by enabling safe, at-home monitoring and drug dosing guidance.
Remote Patient Monitoring (RPM) & Remote Therapeutic Monitoring (RTM)
The company provides integrated technology for remote patient monitoring, event monitoring, software-enabled remote therapeutic monitoring, and cardiac implantable electronic device monitoring. Their platform allows for remote monitoring of patients starting and continuing medications for atrial fibrillation, all from a mobile phone.
Advanced ECG Analysis
SafeBeat Rx utilizes an AI-powered ECG platform that offers beat-by-beat ECG analysis, providing full transparency and the option to adjust measurements for each individual heartbeat. This specialized ECG analysis powers their platform to expand access to remote therapeutic monitoring using third-party FDA-cleared cardiac monitoring devices.
Artificial Intelligence & Machine Learning
Proprietary machine learning algorithms are at the core of SafeBeat Rx's solutions, powering ECG interpretation and treatment management recommendations. Their AI-based ECG analysis software has been validated against expert cardiologist adjudication.
Atrial Fibrillation Management
SafeBeat Rx is developing a medical software solution for safe, at-home ECG monitoring and drug dosing guidance for AFib patients. Their technology aims to replace traditional inpatient hospital stays required for drug initiation and monitoring, allowing patients to manage their heart rhythm disorders remotely.
Drug-Induced QT Prolongation
SafeBeat Rx addresses the critical safety concern of drug-induced QT prolongation, which is a leading cause of FDA nonapproval for many medications. Their AI-powered ECG platform provides accurate QT interval measurements, which is essential for detecting prolonged QT and preventing life-threatening arrhythmias.
Digital Health & Wearables
The platform unlocks the full capabilities of digital health and remote care, utilizing FDA-cleared wearable ECG hardware and integrating with mobile ECG, mobile cardiac telemetry, and implantable cardiac monitors.
Physician Tip

SafeBeat Rx offers physicians a streamlined mobile-first platform with explainable AI and custom tools that display diagnostic information and patient-specific treatment steps, reducing alert fatigue. The technology aims to improve post-discharge cardiac surveillance and provides a novel approach to guideline-adherent pharmacological disease management. It enables safe, at-home initiation and titration of antiarrhythmic drugs, potentially reducing the need for costly and anxiety-inducing inpatient hospital stays. The platform's high QTc accuracy (5u00b17 ms) and 90% accuracy in recommending AAD dosing compared to physicians can enhance clinical decision-making and expand access to life-saving medications, especially for underserved populations.

SafeBeat Rx's specialized ECG analysis powers its platform to expand access to remote therapeutic monitoring using third-party FDA-cleared cardiac monitoring devices, including mobile ECG, mobile cardiac telemetry, and implantable cardiac monitors. The company is also developing a 'SafeBeat Kit' that combines commercially available products like mobile ECG devices, mobile cardiac telemetry, and wearable defibrillators with their proprietary software.

Products by SafeBeat Rx

1 product in the directory

SafeBeat Rx App
SafeBeat Rx, Inc.
Cardiology AI
An AI application designed to support safe pharmacological treatment and monitoring for cardiac arrhythmias.

What the Web Says

SafeBeat Rx is a company focused on developing AI-powered ECG software for cardiac care, aiming to enable remote therapeutic monitoring and expand access to life-saving medications. The company's technology is designed to help clinicians quickly assess patient information from a mobile phone, moving beyond diagnostics to recommend treatment. While direct product reviews from platforms like G2, Glassdoor, Capterra, or Reddit are limited, testimonials from medical professionals and an intern's experience suggest a positive outlook on the company's mission and work environment.

Overall: Positive

Strengths

  • Potential to dramatically improve care for patients requiring in-patient monitoring for drug initiation.
  • May improve patient care and workflows, and reduce healthcare costs.
  • Addresses disparities in antiarrhythmic drug (AAD) hospitalizations, particularly for rural and minority patients.
  • AI-powered ECG platform provides beat-by-beat analysis with high QTc accuracy.
  • Opportunity for employees to contribute meaningfully to the product and work with highly competent individuals.
  • Strong leadership from physician-engineers with a passion for medical innovation.

Limitations

  • Product is currently limited to investigational use only.
  • Limited public reviews available on major platforms like G2, Glassdoor, Capterra, and Reddit for both product and employer.
  • Some general 'Safety Rx' or 'Rx Safe' reviews on Indeed.com mention limited benefits and unprofessional management, though it's unclear if these are directly related to SafeBeat Rx.

Based on reviews from: SafeBeat Rx u2013 Powering Cardiac Therapeutics u2013 All From Your Phone, Novel, automated mobile heart rhythm analysis technology to start antiarrhythmic medications safely at home - NIH RePORTER, SafeBeat Rx Funding | $5M-$10M Revenue | Complete Analysis - Extruct AI, SafeBeat Rx-Moving ECG AI Beyond Diagnostics to Recommending Treatment - PubMed, SafeBeat Rx-Moving ECG AI Beyond Diagnostics to Recommending Treatment | Request PDF - ResearchGate, Top 10 SafeBeat Alternatives & Competitors in 2026 - G2, Jobs at SafeBeat (S21) | Y Combinator's Work at a Startup, SafeBeat Rx-Moving ECG AI Beyond Diagnostics to Recommending Treatment., Certified Cardiac Technician - SafeBeat Rx, Certified Cardiac Technician - SafeBeat Rx - BeBee, Working at Safety Rx: Employee Reviews | Indeed.com, Safety Rx Careers and Employment | Indeed.com, Capterra: Reviews, Pricing, Features in 2026 - SoftwareSuggest, Safe Rx Careers and Employment | Indeed.com, Working at Rx Safe: Employee Reviews | Indeed.com, PioneerRx Reviews 2026. Verified Reviews, Pros & Cons | Capterra, Working at Rx Healthcare Services: Employee Reviews | Indeed.com, Page 2 | OptiMantra Reviews 2026. Verified Reviews, Pros & Cons | Capterra

Last updated: 2026-08-19

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Press & Coverage

SafeBeat Rx
SafeBeat Awarded $2M SBIR Grant to Advance AI-based ECG Analysis for Mobile Therapeutic Monitoring of Atrial Fibrillation Patients: Clinical Study at University of California San Francisco
SafeBeat Rx received a $2M Small Business Innovation Research (SBIR) grant from the National Heart, Lung, and Blood Institute (NHLBI) at NIH to advance its AI-based ECG analysis for mobile therapeutic monitoring of atrial fibrillation patients, with a clinical study at UCSF.
2024-06
Life Science Network
SafeBeat Rx-Moving ECG AI Beyond Diagnostics to Recommending Treatment.
This article introduces SafeBeat Rx, an AI-powered ECG platform that offers beat-by-beat ECG analysis and supports guideline-adherent pharmacological disease management.
2026-06
SafeBeat Rx
SafeBeat Receives Supplement Award for UCSF Phase II SBIR Grant. Advancing Dr. Margaret Ferrari's Career Development.
SafeBeat Rx received a supplement award for its Phase II SBIR grant from NIH, in collaboration with UCSF, to support Dr. Margaret Ferrari's career development in cardiac care innovation.
2026-07
SafeBeat Rx
SafeBeat Celebrates AI-ECG Innovation at Annual AF Symposium, Presents Three New Abstracts
SafeBeat Rx participated in the Annual AF Symposium, presenting three new abstracts on acute and long-term remote monitoring of antiarrhythmic drug titration, educational analysis of AF social media content, and automated QTc measurements.
2025-01
Innolitics
SafeBeat Rx App (K251218) u2014 FDA 510(k)
The SafeBeat Rx App received FDA 510(k) clearance for advisory use by qualified healthcare personnel to evaluate provisional ECG data in conjunction with clinical history.
2026-02
Arkansas Business
HeartX Accelerator announces 5 startups for 2022 program
SafeBeat Rx was selected for the 2022 HeartX accelerator program, which facilitates guaranteed hospital pilot projects and clinical trials for early-stage cardiovascular innovation companies.
2022-10
Business Wire
MedTech Innovator Announces Top 50 Startups Selected for the 2022 Cohort in Tenth Year of World's Largest MedTech Accelerator Program
SafeBeat Rx was named one of the top 50 startups selected for the 2022 MedTech Innovator Accelerator program, the world's largest accelerator of medical technology companies.
2022-06
Preqin
SafeBeat Rx Inc. Asset Profile
SafeBeat Rx Inc. raised non-equity assistance funding led by MedTech Innovator in June 2022.
2022-06

Frequently Asked Questions

SafeBeat Rx is a digital health company that utilizes an AI-powered ECG platform to go beyond diagnostics and guide cardiac therapeutics. It aims to expand access to remote therapeutic monitoring for atrial fibrillation (AFib) patients, enabling them to safely initiate and manage antiarrhythmic medications from home, thereby reducing the need for hospitalization. The platform also addresses concerns about drug-induced QT prolongation, a key safety issue for many medications, by providing beat-by-beat ECG analysis with explainable AI.
SafeBeat Rx integrates with third-party FDA-cleared cardiac monitoring devices, including mobile ECGs, mobile cardiac telemetry, and implantable cardiac monitors, to enable comprehensive remote patient monitoring. Its AI-based software analyzes ECG data to provide diagnostic information and treatment recommendations, streamlining workflows for clinicians and allowing for remote titration and long-term monitoring of cardiac medications. This approach aims to replace traditional inpatient monitoring with a safe, at-home solution.
SafeBeat Rx's AI-based ECG analysis software is currently for investigational use only, and its performance characteristics have not yet been established. The company has submitted an FDA 510(k) application for approval of its QTc algorithm, which is currently underway.
SafeBeat Rx is designed for clinicians by clinicians, with software streamlined for mobile phone use that provides explainable AI and custom tools for diagnostic information and patient-specific treatment steps. The company has received support from organizations like the Heart Rhythm Society and has ongoing collaborations, including a clinical study at the University of California, San Francisco (UCSF) to validate its AI-based ECG analysis software. SafeBeat Rx also partners with manufacturers of FDA-approved wearable cardioverter defibrillators and insurers, aiming to reduce healthcare costs.
SafeBeat Rx was founded in 2020 and has a team of 1-10 employees. It has received funding from investors such as Y Combinator, HeartX Accelerator, Defense TechConnect, MedTech Innovator, LG Nova, and Zillionize. The company has also been awarded a Direct to Phase II Small Business Innovation Research (SBIR) grant of approximately $2M from the National Heart, Lung, and Blood Institute (NHLBI) at the National Institutes of Health (NIH).

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