Science 37
About Science 37
Science 37 is a clinical research company that specializes in decentralized clinical trials (DCTs), aiming to make participation in clinical research more accessible for patients and providers. The company’s model delivers trials directly to patients’ homes, expanding access beyond the geographical limitations of traditional sites. This approach is supported by a proprietary technology platform, the Metasite™, which facilitates patient recruitment, enrollment, and overall clinical trial management. Science 37 leverages telemedicine investigators, mobile nurses, remote coordinators, and connected devices to enable universal access to clinical research.
For physicians, Science 37 offers a way to expand patient access to clinical trials and accelerate the development of new treatments. The company’s solutions are designed to improve patient retention and enroll more representative patient populations. Science 37 operates under a single FDA Form 1572 and a central Institutional Review Board (IRB), with centralized medical oversight and research-grade nursing. Their model has consistently shown strong performance, including high completion rates (approximately 86%) and significant contributions to total study enrollment (an average of 20–30% as a single site), validated by the Tufts Center for the Study of Drug Development (Tufts CSDD). Science 37 has also successfully undergone multiple FDA inspections, resulting in No Action Indicated (NAI) classifications with zero Form 483 observations, supporting various regulatory submissions and approvals.
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Business Intelligence
| Key Investors | Lux Capital, Redmile Group, dRx Capital, PPD, Novartis, Amgen, Sanofi Ventures, GV (formerly Google Ventures), Glynn Capital, LifeSci Ventures, Mubadala Ventures |
| Partnerships | eMed, Catalent, Genentech, AOBiome Therapeutics, Sanofi, Otsuka Pharmaceutical, Novartis, AiCure, VisualDx, Linical, Tufts CSDD |
| Acquisitions | Acquired by eMed, LLC in March 2024 |
| Technology | Network Oriented Research Assistant (NORA) platform, Science 37 Operating System (OS), cloud-native, AI-powered patient matching and screening, EHR integration, patient relationship management, contact center technology |
| FDA Clearances | Multiple FDA inspections with No Action Indicated (NAI) classifications across five Phase 3 studies cleared products (estimated) |
What Physicians Need to Know
For physicians, Science 37 offers a unique opportunity to expand access to clinical research for their patients, particularly those who face geographic or logistical barriers to participating in traditional site-based trials. The platform's use of telemedicine investigators and mobile nurses allows for remote patient monitoring and in-home assessments, reducing the burden on both patients and traditional clinical sites. This can lead to faster enrollment and better retention in studies, ultimately accelerating the development of new treatments. Physicians can also be assured by Science 37's FDA-inspected direct-to-patient site, which validates the regulatory compliance and data quality of their decentralized approach. While Science 37 focuses on clinical trial data collection, it's important to note that some competitors are moving towards more wearable-first data collection, which could offer more passive and integrated patient experiences. Physicians should consider how Science 37's model can complement their existing practice and provide additional care options for their patients.
Science 37's Operating System is designed to be a comprehensive, end-to-end platform for decentralized clinical trials, offering capabilities like eConsent, eCOA, eSource, and telemedicine. They have also partnered with AI and advanced data analytics companies like AiCure to enhance virtual trials, including remote dosing adherence monitoring and digital biomarker measurement. While their platform is robust, some alternatives offer technology without the bundled services wrapper, focusing purely on the digital layer and allowing sponsors to coordinate in-person visits through their existing site networks. Science 37 has also collaborated with CROs like PPD to enable them to utilize Science 37's SaaS-based technology platform for designing and executing digital trials. They are also integrating with solutions like Predoc for AI-powered health information management to streamline data acquisition and accelerate enrollment.
What the Web Says
Science 37 is a clinical research company specializing in decentralized clinical trials (DCTs) through its Metasite model, aiming to increase patient access and accelerate biomedical discovery. While the company's mission and the concept of remote clinical trials are generally viewed positively, employee reviews highlight significant concerns regarding job security, management, and strategic direction. Product reviews for their patient-facing app indicate functionality issues.
Overall: MixedStrengths
- Mission-driven company with a focus on patient access and innovative decentralized clinical trials.
- Offers remote work opportunities, which is a significant plus for many employees.
- Collaborative, knowledgeable, and supportive team environment.
- Robust, comprehensive, and competitive benefits package.
- Opportunity for growth within the company.
- Potential for faster enrollment and better throughput in clinical trials.
Limitations
- High turnover rate and lack of job security, with multiple rounds of layoffs.
- Poor leadership and management, including issues with communication, strategy, and appreciation for employees.
- Product (patient app) experiences technical issues like crashing, login problems, and notification failures.
- Unclear strategic direction and frequent changes in objectives.
- Executive team perceived as out of touch and more concerned with money than patient care.
- Understaffing and heavy workloads.
Based on reviews from: Comparably, SimplyHired, Indeed.com, Reddit, Apple App Store, Google Play Store, SourceForge, PreDoc.ai, Seeking Alpha
Last updated: 2026-09-10
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