Products

Prior Authorization Automation
Surescripts
Prior Authorization
Surescripts' Prior Authorization Automation streamlines medication prior authorizations by retrieving patient data from EHRs and sending it to PBMs, reducing provider intervention and accelerating patient access to treatment.

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About Surescripts

Surescripts is a foundational healthcare technology company operating a comprehensive nationwide health information network, dedicated to streamlining and securing the exchange of critical health intelligence across the U.S. For physicians, Surescripts serves as a vital partner in enhancing patient safety, reducing administrative burdens, and improving the overall quality and cost-effectiveness of care. The company’s offerings extend beyond basic connectivity, providing robust solutions that integrate seamlessly into clinical workflows.

Physicians leverage Surescripts’ network for intelligent prescribing, including electronic prescribing (e-prescribing) and electronic prescribing for controlled substances, which significantly boosts accuracy and efficiency while reducing prescription errors. Furthermore, Surescripts facilitates real-time benefit and price intelligence, enabling physicians to make informed medication choices at the point of care, thereby optimizing patient affordability and adherence. Its intelligent prior authorization solutions aim to accelerate clinically appropriate decisions and minimize manual work, freeing up valuable physician time. The company also provides comprehensive medication history solutions, offering a holistic view of a patient’s past prescriptions to support reconciliation and better care management.

Crucially, Surescripts incorporates artificial intelligence (AI) within its network to optimize existing technologies, enhance data quality, and support faster, more informed clinical and business decisions. For instance, AI is utilized in solutions like electronic prior authorization portals and for parsing clinical attributes from patient records in Record Locator & Exchange and Specialty Medications Gateway. This responsible application of AI helps to close information gaps and empower healthcare professionals with the trusted insights needed to navigate the complexities of modern healthcare, ultimately leading to better patient outcomes.

Focus Areas

Electronic Prescribing Health Information Exchange Prior Authorization Real-Time Prescription Benefit Medication History Clinical Interoperability Care Team Evolution Value-Based Care Specialty Medications Data Management Healthcare Automation AI in Healthcare

Business Intelligence

Key InvestorsTPG Capital, National Community Pharmacies Association (NCPA), National Association of Chain Drug Stores (NACDS), Express Scripts, CVS Caremark
PartnershipsTPG Capital (majority investor and strategic partner), Arcadia (for First-Fill Abandonment solution), Qualifacts (Marketplace integration)
AcquisitionsActiveRADAR (2023), MedAvant Electronic Prescribing Network (2007)
TechnologySurescripts operates a robust health information network utilizing Java and .Net development platforms with an Oracle infrastructure. Their technology leverages a semantic network and AI to power solutions like the Electronic Prior Authorization Portal, break down Consolidated Clinical Document Architectures (CCDAs) for Record Locator & Exchange and Specialty Medications Gateway, and apply machine learning techniques for features like Sig IQ in Medication History. They prioritize network integrity, compliance, and a data management framework focused on accuracy, trust, and stewardship.
FDA ClearancesN/A cleared products (estimated)

What Physicians Need to Know

Electronic Prescribing (E-Prescribing & EPCS)
Surescripts automates the prescribing process, including for controlled substances (EPCS), to enhance speed, accuracy, and patient safety by reducing manual errors and integrating directly into existing workflows.
Health Information Exchange & Clinical Interoperability
Surescripts operates a nationwide health information network that enables seamless and reliable exchange of patient clinical and benefit information across various healthcare settings and professionals. This includes Clinical Direct Messaging and Record Locator & Exchange services, crucial for informed treatment and care transitions.
Prior Authorization
Their solutions, including Intelligent Prior Authorization and Prior Authorization Automation, streamline and often automate the prior authorization process by leveraging clinical insights and benefit intelligence. This significantly reduces administrative burden and treatment delays, with some approvals occurring in seconds.
Real-Time Prescription Benefit
Surescripts provides patient-specific pricing, coverage details, and up to five covered therapeutic alternatives directly within the prescribing workflow. This helps address cost concerns, boost adherence, and avoid coverage barriers at the point of care.
Medication History
They offer comprehensive and accurate medication history services (for ambulatory, reconciliation, and population health) by aggregating data from pharmacy fill records and pharmacy benefit manager (PBM) claims, providing a more complete picture than traditional EHR lists.
Care Team Evolution & Value-Based Care
Surescripts supports evolving care models by integrating more clinical and benefit information into practitioner workflows, fostering collaboration, and providing insights to identify adherence gaps, reduce avoidable costs, and close gaps in care for value-based initiatives.
Specialty Medications
Their solutions simplify the complex prescribing and fulfillment process for specialty medications, accelerating patient access to critical therapies through services like Specialty Patient Enrollment and Specialty Medications Gateway.
Healthcare Automation & AI in Healthcare
Surescripts leverages automation to reduce administrative tasks and applies AI to optimize existing technologies, process vast datasets, and enhance clinical decision-making. AI is used responsibly to identify clinical attributes in patient records and build workflow engines for solutions like prior authorization.
Physician Tip

For physicians, Surescripts stands out by significantly reducing administrative burdens, especially with automated prior authorizations and comprehensive medication history. Their real-time benefit and price intelligence, delivered directly within the EHR, empowers more informed prescribing decisions, helps patients afford medications, and improves adherence. The robust nationwide network ensures critical patient information is accessible at the point of care, leading to safer, more efficient, and higher-quality patient care. This allows physicians to spend more time focusing on patients rather than paperwork.

Surescripts is deeply integrated into the healthcare ecosystem, connecting virtually all Electronic Health Records (EHRs), health systems, pharmacies, health plans, and Pharmacy Benefit Managers (PBMs) through its nationwide network. As a designated Qualified Health Information Network (QHIN) via Interconnect, Surescripts facilitates broad data exchange under the Trusted Exchange Framework and Common Agreement (TEFCA) and leverages frameworks like Carequality, ensuring seamless interoperability across diverse platforms.

Products by Surescripts

1 product in the directory

Prior Authorization Automation
Surescripts
Prior Authorization
Surescripts' Prior Authorization Automation streamlines medication prior authorizations by retrieving patient data from EHRs and sending it to PBMs, reducing provider intervention and accelerating patient access to treatment.

What the Web Says

Surescripts is a healthcare technology company that operates a nationwide health information network, primarily known for its e-prescribing platform. Reviews indicate that its e-prescribing product is generally efficient and streamlines workflows for healthcare professionals, though some users report difficulties with combination prescriptions and automated refill requests. As an employer, Surescripts receives mixed reviews, with some highlighting a strong mission and positive culture, while others point to issues with management and employee development.

Overall: Mixed

Strengths

  • Efficient e-prescribing for quick medication management.
  • Easy to add pharmacy information and search for drugs, doses, and directions.
  • Streamlines clinical workflows and reduces administrative burden.
  • Enhances patient safety with built-in drug interaction checks.
  • Valuable company mission in e-prescribing and continuity of care.
  • Strong work-life balance and positive company culture reported by some employees.

Limitations

  • Some combination prescriptions can be difficult to find.
  • Automated refill requests can be problematic and lead to confusion.
  • Poor training and employee development.
  • Issues with management, including lack of attention to detail and poor interpersonal skills.
  • Stiff company culture reported by some employees.
  • Advancement opportunities can be challenging due to a fairly flat organizational structure.

Based on reviews from: Indeed.com, SimplyHired, G2.com, Gartner, Elion Health, Reddit, Capterra

Last updated: 2026-07-22

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Press & Coverage

Business Wire
Surescripts Recognized as One of the Best Places to Work in Healthcare in 2026
Surescripts was recognized as one of the best places to work in healthcare in 2026.
2026-05
Business Wire
Surescripts Expands Prior Authorization Automation, Enabling 50% More Prescribers Nationwide to Improve Medication Access for Patients in 2026
Surescripts announced the expansion of its Prior Authorization Automation solution, increasing the number of enabled prescribers by 50% since December 2025, now totaling 68,000 across 42 health systems.
2026-05
Business Wire
New Surescripts Survey Results: More Than Half of Patients Hit Roadblocks Accessing Their Prescriptions
A new national survey by Surescripts revealed that over half of patients encounter difficulties accessing their prescriptions, with cost, delays, and prior authorizations being significant barriers.
2026-06
BioSpace
Surescripts Annual Impact Report Shows Collaboration, Innovation Gains in Interoperability, Prior Authorization Automation and Medication Access in 2025
Surescripts released its 2025 Annual Impact Report, highlighting significant advancements in health data interoperability, improved efficiency for care providers, and enhanced patient access to prescription therapy.
2026-03
Surescripts
Surescripts RxTransfer Saves Time for Pharmacists and Prescribers with Seamless Communication, Ensuring Patients Have Access to Needed Medications Without Delay
Surescripts announced strong adoption of its RxTransfer solution, including across 4,800 Walmart locations, enabling electronic prescription transfers and reducing administrative burden.
2026-03
Surescripts
The health intelligence platform behind virtually every prescription
Surescripts details its health intelligence platform, emphasizing its role in secure health data exchange, high uptime, and continuous innovation for improved patient care.
2026-07
Surescripts
Surescripts Announces Strategic Partnership with TPG to Enhance Patient Care and Meet Evolving Healthcare Needs Nationwide
Surescripts announced that TPG, a global alternative asset management firm, will become a majority investor, aiming to accelerate the development and scaling of Surescripts' solutions.
2024-10
Healthcare Dive
FTC reaches proposed settlement with Surescripts in antitrust case
The Federal Trade Commission reached a proposed settlement with Surescripts in an antitrust case, which will prohibit Surescripts from imposing exclusivity agreements and enforcing non-compete clauses.
2023-07

Frequently Asked Questions

Surescripts' E-Prescribing and Real-Time Prescription Benefit solutions integrate directly into your EHR, providing patient-specific pricing, coverage details, and therapeutic alternatives at the point of care. This helps reduce medication errors, address cost concerns, and improve patient adherence by flagging prior authorization requirements and offering lower-cost options.
Surescripts offers Medication History solutions (Ambulatory, Populations, Reconciliation) and Clinical Direct Messaging to provide a comprehensive view of patient medication history, fill data gaps, and enable secure exchange of clinical documents. This robust interoperability, facilitated by the Surescripts Network Alliance and Carequality framework, enhances care coordination, informs treatment decisions, and reduces administrative burden across care settings.
Surescripts' Electronic Prior Authorization and Prior Authorization Automation solutions integrate into your workflow, automatically retrieving clinical data from the EHR to expedite approvals and reduce manual processes. For specialty medications, solutions like Specialty Medications Gateway and Specialty Patient Enrollment streamline prescribing, patient enrollment, and allow pharmacists to access critical clinical information directly.
Surescripts prioritizes robust data management with a focus on accuracy, trust, and compliance, underpinning its network integrity and security. They leverage healthcare automation and AI in products like Prior Authorization Automation and Record Locator & Exchange to optimize workflows, reduce administrative burdens, and support faster, more informed clinical decisions, viewing AI as a tool to enhance human judgment.
Surescripts adheres to stringent compliance standards, including HITRUST r2 Certification, EHNAC, and DirectTrust accreditations, and operates as a HIPAA Business Associate, ensuring rigorous data security and patient privacy. They offer comprehensive support through resources like a Workbench, Independent Pharmacy Helpline, Learning Center, and a dedicated Prior Authorization Portal for healthcare organizations.
While specific pricing details for providers are not publicly disclosed, Surescripts' solutions are designed for seamless integration into virtually all existing EHR systems, often through partnerships with EHR vendors. Their value proposition focuses on reducing administrative costs and improving patient outcomes by embedding critical health intelligence directly into clinical workflows.
Surescripts supports value-based care by providing comprehensive patient medication history and care activity insights, enabling providers to identify adherence opportunities and close care gaps. They also facilitate the evolution of care teams by empowering all clinicians, including pharmacists, with shared clinical and cost information within their workflows to address primary care shortages and enhance collaborative patient care.

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