Surgalign

Deerfield, Illinois, United States  All United States companies → Founded 1997
Medical Device / Hardware Specialty-Focused AI
Neurosurgery Orthopedics Radiology
Radiology & Imaging AI Surgical AI
Public (formerly), Out of Business (Digital Health Assets acquired) — $210M+

Products

HOLO Portal
Surgalign
Radiology & Imaging AI
HOLO Portal is Surgalign's AI-driven augmented reality surgical guidance system, designed to assist surgeons in spine procedures by segmenting and labeling anatomy for planning screw trajectories and overlaying the plan during surgery.

See all 1 product →

About Surgalign

Surgalign Holdings, Inc. is a global medical technology company dedicated to advancing spine care through innovative solutions, including digital technologies, to improve patient outcomes. The company offers a comprehensive portfolio of spinal hardware implants for various procedures, such as fusion in the lumbar, thoracic, and cervical spine, motion preservation solutions for the lumbar spine, and a minimally invasive surgical implant system for sacroiliac joint fusion. They also provide a range of advanced and traditional orthobiologics (biomaterials).

A key focus for Surgalign is its HOLO AI platform, an artificial intelligence-driven, augmented reality (AR) guidance system for spine surgery. This platform utilizes AI to process intraoperative images, autonomously segmenting and labeling anatomy, and planning patient-specific pedicle screw trajectories that are then approved by the surgeon. The HOLO Portal system, part of this platform, uses AR to overlay the segmented AI reconstruction over the patient’s actual anatomy, providing real-time 3D visualization during surgical procedures to guide instruments and enhance precision. Surgalign aims to integrate this digital surgery platform to improve patient outcomes and drive the adoption of its spinal hardware implants and biomaterials products.

Focus Areas

Spinal implants Digital surgery Artificial intelligence Augmented reality Surgical navigation Orthobiologics Motion preservation Minimally invasive surgery

Business Intelligence

Key InvestorsWater Street Healthcare Partners
PartnershipsPRIA Healthcare, Dr. Pierce Nunley (Spine Institute of Louisiana), Dr. Alexander Vaccaro
AcquisitionsHolo Surgical Inc. (acquired by Surgalign), Inteneural Networks (investment by Surgalign), Prompt Prototypes (acquired by Surgalign). Surgalign's Digital Health Assets were acquired by Augmedics, and its Hardware and Biologics Business was acquired by Xtant Medical Holdings.
TechnologyHOLO AI digital health platform, HOLO Portal surgical guidance system (AI-driven augmented reality), TETRAfuse® 3-D
FDA Clearances2 (HOLO Portal surgical guidance system, Cortera spinal fixation system) cleared products (estimated)

What Physicians Need to Know

Specialization
Surgalign specializes in healthcare AI tools, primarily focusing on digital health solutions for spine surgery and degenerative spinal conditions. Their core offering, the HOLO Portalu2122 system, is an AI-driven augmented reality (AR) guidance system for spine procedures. They also have a portfolio of spinal hardware implants and orthobiologics.
Key Differentiators
Surgalign's key differentiators include being the world's first AI-driven AR guidance system for spine surgery (HOLO Portalu2122). Their technology combines machine learning-based image guidance with AR, automated spine segmentation (anatomy recognition), and automated surgical planning using proprietary AI software. This allows for real-time 3D visualization of patient anatomy directly in the surgeon's field of vision.
Technology Stack
Their technology stack is centered around their HOLO AI digital health platform. This platform utilizes deep learning technology driven by convolutional neural network (CNN) algorithms for automated medical image analysis, including segmenting medical images, measuring anatomic structures, and planning pedicle screw placement. The HOLO Portal system integrates this AI with augmented reality (AR) displays.
AI Insights for Research
Surgalign has also launched HOLO AI Insights, an AI platform for automated medical image analysis, initially for neurovascular research. This platform can automate volumetric analysis of vascular structures on MRI, offering a significant leap in efficiency for longitudinal comparisons. It also provides quantitative measurements of 16 different anatomic structures in the spine from lumbar spine MRI images for retrospective data analysis and clinical research.
Physician Tip

For physicians, Surgalign's HOLO Portal system offers several advantages. It provides intelligent solutions designed to improve patient outcomes by delivering more accurate and efficient care in the surgical environment. The system's AI autonomously processes intraoperative images to create patient-specific plans and displays anatomy in 3D using AR, which can lead to less tissue damage due to improved visualization. Surgeons can leverage this technology to gain information they might currently be missing, enhancing surgical decisions and potentially reducing operative time. Additionally, HOLO AI Insights can assist in clinical research by transforming unstructured medical imaging data into structured datasets for new clinical insights.

Surgalign's HOLO AI digital health platform is designed with a vision for broader application across various healthcare specialties and throughout the care continuum. The HOLO AI Insights platform is integrated with the HOLO Portal spine system. While the company has faced bankruptcy proceedings and its digital health assets were acquired by Augmedics in 2023, the underlying technology and its potential for integration within augmented reality surgical navigation platforms remain significant.

Products by Surgalign

1 product in the directory

HOLO Portal
Surgalign
Radiology & Imaging AI
HOLO Portal is Surgalign's AI-driven augmented reality surgical guidance system, designed to assist surgeons in spine procedures by segmenting and labeling anatomy for planning screw trajectories and overlaying the plan during surgery.

What the Web Says

Surgalign, a medical technology company focused on spine care, has faced significant challenges, including filing for Chapter 11 bankruptcy in June 2023 and settling with the SEC for inflating reported revenue between 2015 and 2019. While some former employees praised the company culture and management, others cited a lack of fiscal controls and a decline in the work environment leading up to its bankruptcy. Surgalign developed products like the Coflex Interlaminar Stabilization device and the HOLO AI system for spine surgery.

Overall: Negative

Strengths

  • Developed and distributed great products, such as the Coflex device and HOLO AI.
  • Wonderful company culture and supportive colleagues (prior to bankruptcy).
  • Excellent management and growth opportunities (prior to bankruptcy).
  • Good benefits (prior to bankruptcy).
  • HOLO AI technology has significant market opportunity in healthcare.

Limitations

  • Company filed for Chapter 11 bankruptcy in June 2023.
  • Lacked fiscal controls, leading to a flagship development project being a commercial failure.
  • Inflated reported revenue by shipping products early without customer approval between 2015 and 2019.
  • Settled with the U.S. Securities and Exchange Commission for $2 million due to past activities.
  • Work environment declined and company shut down due to running out of money.
  • Received notice of non-compliance with minimum stockholders' equity requirement in April 2023.

Based on reviews from: Indeed.com, Reddit, symplr, Becker's Spine Review, YouTube, SEC Filing (Form 8-K), IndexBox

Last updated: 2026-06-19

Videos

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Press & Coverage

FirstWord HealthTech
FDA clears Surgalign's HOLO Portal system for spine surgery | FirstWord HealthTech
Surgalign announced that its HOLO Portal surgical guidance system received FDA 510(k) clearance for use within lumbar spine procedures, representing the world's first artificial intelligence (AI)-driven augmented reality (AR) guidance system for spine.
2022-01
GlobeNewswire
Surgalign Announces FDA 510(k) Clearance of the Corterau2122 Spinal Fixation System u2013 The Company's New Flagship Posterior Fixation Platform - GlobeNewswire
Surgalign Holdings, Inc. announced FDA 510(k) clearance of the Corterau2122 Spinal Fixation System, a new flagship product designed to drive future growth and enable market share gains in the posterior fixation market.
2022-08
BioSpace
Surgalign To Collaborate with Dr. Alexander Vaccaro and Dr. Pierce Nunley to Advance HOLOu2122 AI Insights and its Artificial Intelligence Technologies - BioSpace
Surgalign Holdings, Inc. announced new collaborative alliances with Dr. Pierce Nunley and the Spine Institute of Louisiana, and Dr. Alexander Vaccaro, to advance its HOLOu2122 AI Insights solution for lumbar spine imaging.
2023-05
MedTech Dive
Augmedics picks up Surgalign's digital health assets for $900K | MedTech Dive
Augmedics acquired the digital health assets of Surgalign Holdings for $900,000 in cash, strengthening its augmented reality and AI portfolio.
2023-08
Xtant Medical Holdings Inc.
Xtant Medical Completes Acquisition of Surgalign's Hardware and Biologics Business
Xtant Medical Holdings, Inc. completed the acquisition of certain assets and liabilities related to the domestic and international biologics and spinal fixation offerings of Surgalign Holdings, Inc. for $5 million.
2023-08
Orthopedics This Week
Surgalign Declares Bankruptcy | Orthopedics This Week
Surgalign Holdings, Inc. initiated bankruptcy proceedings under Chapter 11 of the United States Bankruptcy Code.
2023-07
Fierce Biotech
Surgalign sells off spinal implant product lines for $17M amid attempt to slash spending
Surgalign sold its Coflex and Cofix product lines to Xtant Medical Holdings for $17 million, as part of a restructuring plan to focus on its artificial intelligence products.
2023-03
r/biotech_stocks (Reddit)
Surgalign finally agreed to settle $2.07M with investors over boosted reported revenue
Surgalign settled with investors over claims related to inflated reported revenue between 2015 and 2019, agreeing to fund a $2.075M SEC Fair Fund.
2026-02

Frequently Asked Questions

Surgalign's primary AI-powered product is the HOLO Portalu2122 surgical guidance system, an AI-driven augmented reality (AR) system for spine surgery that assists with automated spine segmentation and surgical planning. They also offer HOLO AI Insights, a cloud-based platform that uses AI to analyze lumbar spine MRI images, providing quantitative measurements of anatomical structures for research and potentially for clinical decision support.
Surgalign's HOLO Portalu2122 surgical guidance system received U.S. Food & Drug Administration (FDA) 510(k) clearance for use in lumbar spine procedures in January 2022. The company has a stated commitment to developing solutions that predictably deliver superior clinical and economic outcomes, and their AI technologies are designed to enhance surgical precision and inform clinical decisions.
Information regarding the specific pricing model for Surgalign's AI products (HOLO Portal and HOLO AI Insights) is not publicly detailed in the provided search results. To assess cost-effectiveness, institutions would typically need to engage directly with Surgalign for a detailed proposal, including pricing, implementation costs, and potential return on investment based on anticipated improvements in surgical outcomes and efficiency.
While specific details on support and training programs are not extensively outlined, Surgalign emphasizes working with surgeons to enhance system functionality and expand use cases. Their approach involves integrating feedback from leading spine surgeons to refine their technology, suggesting a collaborative support model.
Surgalign has collaborated with institutions like the San Diego Spine Foundation and key spine surgeons such as Dr. Alexander Vaccaro and Dr. Pierce Nunley to advance their HOLO AI Insights solution and evaluate its potential. They also acquired Holo Surgical in 2020, which was instrumental in developing the HOLO Portal system's AI and AR technology.
Surgalign filed for Chapter 11 bankruptcy in June 2023 and has been in the process of selling off its assets. Augmedics successfully bid for Surgalign's digital health assets, including the HOLO AI and AR portfolio, for $900,000. This indicates that while Surgalign as an independent entity faced significant financial challenges, its AI technologies are being acquired and may continue to be developed under new ownership.

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