Syapse

San Francisco, California, United States  All United States companies → Founded 2008
Healthcare Analytics / BI Specialty-Focused AI
Hematology Oncology
Oncology AI
Acquired (by N-Power Medicine on January 13, 2025) — $223M

Products

Syapse Precision Medicine
Syapse
Oncology AI
Syapse Precision Medicine is an AI tool designed to support the clinical implementation of precision oncology. It is primarily for oncologists and healthcare systems, including academic and community cancer centers. [3, 7, 9] What it does: The platform integrates clinical and genomic data to provide insights at the point of care. [3, 8, 9] It […]

See all 1 product →

About Syapse

Syapse is a healthcare AI company dedicated to advancing precision medicine, particularly in oncology, through the generation and application of real-world evidence. The company’s platform is designed to integrate previously fragmented clinical, molecular, treatment, and health outcomes data, transforming it into actionable insights. This empowers physicians, especially oncologists, to deliver personalized care at the point of care by providing comprehensive patient insights derived from real-world data.

Syapse collaborates with leading health systems, life sciences companies, and regulators to build a “Learning Health Network.” This network aims to improve outcomes in cancer care by facilitating data sharing and the application of real-world evidence, ultimately striving to ensure all cancer patients have access to the best precision care, regardless of their location or income. Their solutions support the clinical implementation of oncology precision medicine through genomic data integration, decision support, care coordination, and quality improvement.

By leveraging advanced technologies, Syapse plays a pivotal role in making healthcare more personalized and efficient. Their efforts are focused on bridging gaps in access to quality care, particularly in underserved communities, to ensure patients receive the most effective treatments based on the latest research and clinical insights.

What Physicians Need to Know

Precision Oncology Solutions
Syapse specializes in providing a comprehensive software suite for precision medicine, particularly in oncology, enabling personalized cancer care based on a patient's clinical and genomic profile.
Real-World Evidence (RWE) Transformation
The company transforms real-world evidence into actionable insights to directly impact patient care. Their AI-enhanced data platform, Raydar, processes large amounts of RWD to generate critical insights.
Data Sharing Network
Syapse operates a Data Sharing Network, which serves as a unique hub for doctors from various hospital systems to pool their collective experience for the benefit of patients.
Clinical Trial Acceleration
Syapse's platform helps accelerate clinical trial enrollment by matching patients to precision trials at the point of care.
Clinical Decision Support & Care Coordination
Their platform facilitates clinical and genomic data integration, offers decision support, and enhances care coordination and quality improvement at the point-of-care.
Physician Tip

For physicians, Syapse's tools offer the ability to deliver personalized cancer care by integrating clinical and genomic data, providing actionable insights at the point of care. The platform empowers oncologists with real-world evidence, allowing them to view treatments and outcomes from a broad network of patients to inform their own treatment decisions. It also streamlines access to relevant clinical trials and supports Molecular Tumor Boards in recommending targeted therapies, ultimately aiming to improve patient outcomes and increase progression-free survival.

Syapse was acquired by N-Power Medicine on December 30, 2024. As a result, Syapse's extensive network of community-based health systems, its data and technology stack, and its dedicated team are now integrated into N-Power Medicine's AI-powered point-of-care platform and Kaleido Registry. This integration aims to establish a larger community-based prospective clinical research network, enhancing access to clinical trials for community oncologists and patients, particularly in underserved populations. Key technologies mentioned in Syapse's stack include MongoDB, React, Oracle, and HTTP/3, alongside their AI-enhanced data platform, Raydar.

Products by Syapse

1 product in the directory

Syapse Precision Medicine
Syapse
Oncology AI
Syapse Precision Medicine is an AI tool designed to support the clinical implementation of precision oncology. It is primarily for oncologists and healthcare systems, including academic and community cancer centers. [3, 7, 9] What it does: The platform integrates clinical and genomic data to provide insights at the point of care. [3, 8, 9] It […]

What the Web Says

Syapse, a company focused on enabling precision medicine for cancer patients, receives mixed reviews regarding both its product and its work environment. While some employees praise its mission and supportive culture, others criticize management, product ambiguity, and a toxic work atmosphere. Product reviews are scarce on major platforms like G2 and Capterra for the specific 'Syapse' company focused on precision medicine, but other companies with 'Synapse' in their name (e.g., Synapse by Patsnap, Synapse Medicine, Synapse Health, Synapse Software, and Razer Synapse) have reviews available, making it crucial to distinguish between them.

Overall: Mixed

Strengths

  • Meaningful mission in precision medicine for cancer patients.
  • Supportive management and respectful colleagues (in some departments).
  • Good PTO and healthcare benefits.
  • Opportunities to socialize and emphasis on work-life balance.
  • Potential for making a tangible impact in healthcare.
  • Product helps perform warehouse duties within a single system (for Synapse Warehouse Management System).

Limitations

  • Challenging and toxic work environment with political dynamics.
  • Loads of ambiguity in product, requirements, expectations, and timelines.
  • Terrible product that provides no value or revenue streams, with useless data (according to some employees).
  • Unreliable PMO and misaligned executive leadership.
  • Constant ridicule and intimidation behavior by managers.
  • Poor work-life balance, pay, benefits, job security, and advancement ratings.

Based on reviews from: Indeed.com, G2.com, Reddit, Capterra, Elion Health, BevNET.com

Last updated: 2026-07-22

Videos

News, demos, and interviews about Syapse.

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Press & Coverage

GlobeNewswire
Syapse Announces $35 Million Growth Investment with Innovatus Capital Partners to Expand Delivery of Real-World Evidence Through Syapseu2019s Learning Health Network
Syapse closed a $35 million growth funding round led by Innovatus Capital Partners, with participation from existing investors. The funding will expand its focus on providing real-world insights to partners to improve outcomes for cancer patients.
2022-07
GlobeNewswire
Syapse Expands Oncology Real-World Data Offerings with Introduction of Syapse Cohorts: Essentials
Syapse launched Syapse Cohorts: Essentials, a new real-world data offering designed to provide cancer researchers and life sciences companies with fit-for-purpose datasets across various cancer types. This expands upon their existing Enriched Cohorts offering.
2024-05
Clinical Trials Arena
Signal: FDA renews Syapse collaboration to use real-world data in oncology
The FDA's Oncology Center of Excellence renewed a four-year collaboration agreement with Syapse to evaluate real-world data study designs and methods for informing regulatory objectives. The partnership aims to explore the potential uses of real-world data in regulatory decision-making.
2023-12
Journal of Personalized Medicine
Improvements in Clinical Cancer Care Associated with Integration of Personalized Medicine
This peer-reviewed article, co-authored by Syapse personnel, discusses how a higher personalized medicine integration score within healthcare institutions is significantly associated with a higher percentage of metastatic non-small cell lung cancer patients receiving targeted therapies.
2024-09
Canaccord Genuity
Syapse has been acquired by N-Power Medicine to Expand its Next-Generation Community-Based Network for Oncology Clinical Research and Clinical Trials
Syapse was acquired by N-Power Medicine in a stock-for-stock exchange, aiming to expand access to prospective clinical trials and life-saving innovations for cancer patients in community settings.
2024-12
Applied Clinical Trials Online
Medidata and Syapse Announce Partnership
Medidata and Syapse partnered to transform oncology clinical trials for the age of precision medicine, focusing on designing eligibility criteria, identifying trial sites, and gathering appropriate patients.
unknown
JCO Clinical Cancer Informatics
Quality Assurance and Technology-Enabled Curation of Oncology Real-World Data
This article details Syapse's robust quality-control processes for technology-enabled curation of oncology real-world data, highlighting their proprietary 4-branch QC program to ensure data accuracy and consistency.
unknown
GlobeNewswire
Syapse Announces New Real-World Data Studies Published at 2021 American Society for Clinical Oncology Annual Meeting
Syapse announced the publication of five abstracts at the ASCO 2021 Annual Meeting, showcasing studies that utilized Syapse's real-world data capabilities to draw conclusions for improving clinical care and patient outcomes.
2021-06

Frequently Asked Questions

Syapse primarily offers the Precision Medicine Platform, which integrates clinical and genomic data to support precision oncology. Their AI-enhanced data platform, Raydar, processes large amounts of real-world data to generate critical insights, aiding in decision support, care coordination, and outcomes tracking for cancer patients.
Syapse operates within its Learning Health Network, handling sensitive patient data, and collaborates with the FDA on real-world data initiatives, which necessitates adherence to stringent healthcare data regulations. While specific certifications like HIPAA were not explicitly detailed, the nature of their work implies robust data security and privacy protocols are in place to manage patient information.
Syapse's pricing model is not publicly disclosed, which is typical for enterprise-level healthcare software solutions that are often customized. Healthcare organizations interested in their precision medicine platform would need to contact Syapse directly for a detailed quote tailored to their specific needs and scale of implementation.
While specific support details are not extensively publicized, Syapse's partnerships with major health systems for implementing precision medicine programs suggest comprehensive services. These likely include software deployment, integration into existing electronic health record systems, and ongoing support for clinical and operational teams to ensure effective utilization.
Syapse partners with a network of leading health systems, including Henry Ford Health System, CommonSpirit Health, and Providence St. Joseph Health, to build its Learning Health Network. They also collaborate with biopharmaceutical companies like Amgen and Pfizer, and regulatory bodies such as the FDA, to advance real-world evidence and accelerate precision oncology.
Syapse has demonstrated significant financial backing, raising a total of $223 million in funding over nine rounds from various institutional investors. In January 2025, Syapse was acquired by N-Power Medicine, indicating a strategic integration aimed at expanding community-based oncology clinical research and trials.
Syapse utilizes its AI-enhanced platform, Raydar, to process real-world data, and its collaboration with the FDA includes evaluating real-world data study designs and methods, which inherently involves addressing data quality and potential biases. General AI in healthcare compliance emphasizes understanding AI outputs, mitigating bias, and ensuring human oversight to promote ethical deployment.

Investors

Who's funded Syapse.

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