Therenva SAS
About Therenva SAS
Therenva SAS is a healthcare AI company specializing in advanced imaging software solutions for cardiovascular procedures. Their core offerings, EndoSize and EndoNaut, are designed to assist physicians and healthcare professionals throughout the planning and execution of minimally invasive endovascular interventions. EndoSize provides AI-based image processing for accurate and efficient segmentation and detection of anatomical structures, facilitating precise measurements and comprehensive case planning for various cardiovascular pathologies, including aortic aneurysm repair, aortic dissections, carotid artery disease, peripheral artery disease, and structural heart interventions like TAVI/TAVR and TMVR.
EndoNaut, a patented solution, offers intra-operative 3D navigation and localization of devices. It aligns pre-operative 3D data from EndoSize with 2D fluoroscopic images, providing real-time guidance, enhanced accuracy, and visual comfort during catheterization procedures. This integration of AI, deep learning, and biomechanical simulation in their software toolset aims to standardize and streamline workflows, ultimately improving patient care by enabling more efficient and safer endovascular interventions.
Since its acquisition by Ziehm Imaging in 2020, Therenva’s portfolio is being leveraged globally through Ziehm’s distribution network, with a focus on co-developing new solutions for enhanced pre- and intra-operative image-based decision support systems in cardiovascular and potentially other clinical areas.
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| Key Investors | Europa (prior to acquisition), Ziehm Imaging (acquirer) |
| Partnerships | Ziehm Imaging (parent company and technology partner), Bucharest Sanador Clinic, CHUV Lausanne |
| Acquisitions | Acquired by Ziehm Imaging on July 27, 2020 |
| Technology | AI-based image processing, deep learning, biomechanical simulation, image fusion technology, compatible with mobile and fixed C-arms, DICOM integration |
| FDA Clearances | 2 cleared products (estimated) |
What Physicians Need to Know
Therenva's solutions, EndoSize and EndoNaut, are designed to significantly enhance precision and safety in endovascular interventions through AI-powered planning and navigation. Physicians can expect streamlined preoperative workflows with automated measurements and rapid case planning, saving valuable time. The image fusion technology in EndoNaut helps to substantially reduce patient and staff exposure to X-ray radiation and contrast media. Detailed 3D anatomical models, predictive simulations of vascular deformation, and comprehensive planning reports empower physicians with better decision-making capabilities for optimal treatment strategies and device selection. The versatility of their applications covers a broad spectrum of cardiovascular procedures, from complex aneurysm repair and TAVI/TMVR to peripheral artery disease treatments. Furthermore, EndoNaut's compatibility with existing C-arm systems and intuitive control directly from the interventional table ensures seamless integration into any operating room environment.
Therenva's EndoNaut system is engineered for broad compatibility, integrating seamlessly with most existing mobile and fixed C-arm systems from various manufacturers. The software facilitates efficient data flow by supporting direct DICOM image import from PACS, medical cloud systems, hard disks, and CD-ROMs for both preoperative planning and intraoperative navigation. Therenva has a notable strategic partnership with Ziehm Imaging, which enables deeper software and hardware integration, leading to enhanced and more seamless workflows for clinicians.
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