Products

VBrain-OAR
Vysioneer
Neurology AI
VBrain-OAR by Vysioneer is an FDA-cleared AI software for automated contouring of organs at risk (OAR) in brain MRI images and multi-modality image registration, designed to assist in radiation treatment planning.
VBrain
Vysioneer
Oncology AI
VBrain is the first-ever FDA-cleared AI-powered tumor auto-contouring solution, designed to optimize brain tumor radiosurgery with enhanced precision and efficiency.

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About Vysioneer

Vysioneer is an oncology AI company dedicated to transforming cancer care through the application of machine learning. Their core mission is to expedite the delivery of effective therapies to cancer patients by enhancing drug efficacy with lesion-level precision. The company leverages its proprietary, FDA-cleared, cloud-based AI platform to augment clinicians’ productivity and facilitate precision medicine, ultimately aiming for improved patient outcomes.

For physicians, Vysioneer’s technology offers practical solutions, such as their featured product, VBrain. This is a pioneering tumor auto-contouring system designed to optimize brain tumor radiosurgery by identifying common brain tumors like metastasis, meningioma, and acoustic neuroma. This capability significantly accelerates the radiosurgery treatment planning workflow, providing a “second set of eyes and hands” to assist in analyzing and segmenting medical scans. Beyond brain tumors, their platform supports automatic image analysis for various clinical findings across different imaging modalities.

Vysioneer’s AI solutions are actively utilized in both clinical practice and pharmaceutical clinical development, with collaborations including Pfizer and the Stanford Cancer Institute. The company aims to establish a new standard for evaluating drug efficacy, providing data with significantly higher granularity (10 to 50 times more) than current methods. This enhanced data can enable pharmaceutical companies to make earlier and more confident decisions in clinical trials, thereby accelerating the development and approval of new cancer treatments.

Focus Areas

Oncology AI Tumor Auto-Contouring Radiation Therapy Radiosurgery Drug Efficacy Assessment Clinical Trials Brain Tumors (Metastasis Meningioma Acoustic Neuroma) Lesion-Level Insights Precision Medicine

Business Intelligence

Key InvestorsChaac Ventures, JLABS
PartnershipsPfizer, MC Medical, Stanford Cancer Institute, GE Healthcare, Mary Bird Perkins Cancer Center, NVIDIA
TechnologyCloud-based AI platform, Deep Learning Technology, Neural Network-based AI solution, Vendor-neutral, GPU-accelerated compute ecosystem
FDA Clearances1 cleared products (estimated)

What Physicians Need to Know

Oncology AI & Deep Learning
Vysioneer leverages proprietary deep learning technology to transform cancer care, augmenting clinicians' productivity and delivering precision medicine.
Tumor Auto-Contouring (VBrain)
VBrain is the first-ever FDA-cleared AI-powered tumor auto-contouring solution, specifically for brain tumors. It significantly reduces manual contouring time from hours to minutes, enhancing efficiency and accuracy in radiation therapy planning.
Radiation Therapy & Radiosurgery
VBrain optimizes brain tumor radiosurgery with enhanced efficiency and efficacy, enabling quicker response times and more precise tumor targeting. It integrates seamlessly into existing clinical workflows.
Drug Efficacy Assessment & Clinical Trials
Vysioneer's AI platform evaluates drug efficacy down to the individual tumor level, providing 10 to 50 times more granularity than traditional methods. They are the first AI company to deploy an AI system in pharma-sponsored prospective trials for efficacy evaluation, collaborating with companies like Pfizer and academic institutions like Stanford Cancer Institute.
Brain Tumors Specialization
VBrain applies auto-contouring to the three most common types of brain tumors: brain metastasis, meningioma, and acoustic neuroma.
Lesion-Level Insights & Precision Medicine
The company focuses on unlocking lesion-level insights to address tumor heterogeneity, enabling more personalized cancer medicine and improving the understanding of long-term treatment outcomes. This approach helps identify the right treatment for the right patient at the right time.
Physician Tip

For physicians, Vysioneer's solutions, particularly VBrain, offer significant advantages by acting as a 'second set of eyes and hands' to enhance accuracy and efficiency in radiation oncology. You can expect a dramatic reduction in manual contouring time (up to 30.8% decrease in treatment planning time), allowing more focus on patient care. The AI demonstrates higher sensitivity (12.2%) for lesion detection, even identifying lesions that might be missed by the human eye, and improves contouring accuracy for clinicians of all skill levels. This leads to more precise treatment planning and potentially better patient outcomes. For those involved in clinical trials, Vysioneer's AI provides unparalleled granularity in drug efficacy assessment, enabling earlier and more confident decisions in drug development and exploring novel endpoints beyond traditional RECIST criteria.

Vysioneer's VBrain is a cloud-based, vendor-neutral solution designed for seamless integration into existing clinical workflows, supporting data routing to and from DICOM nodes within a hospital network. They have established collaborations with major healthcare technology providers like GE Healthcare to make their solutions available on GE equipment, further facilitating integration into diverse clinical environments. The company also works with NVIDIA, leveraging GPUs for accelerated development and deployment, and plans to make AI solutions available on NVIDIA NGC for streamlined software delivery.

Products by Vysioneer

2 products in the directory

VBrain-OAR
Vysioneer
Neurology AI
VBrain-OAR by Vysioneer is an FDA-cleared AI software for automated contouring of organs at risk (OAR) in brain MRI images and multi-modality image registration, designed to assist in radiation treatment planning.
VBrain
Vysioneer
Oncology AI
VBrain is the first-ever FDA-cleared AI-powered tumor auto-contouring solution, designed to optimize brain tumor radiosurgery with enhanced precision and efficiency.

Reviews & Opinions

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Press & Coverage

Vysioneer
Vysioneer's Collaboration with Pfizer Oncology Highlighted in Washington Post Live Interview
Vysioneer's collaboration with Pfizer Oncology was featured in a Washington Post Live Interview, showcasing their work in advancing cancer care with AI.
2025-10
Vysioneer
ESMO Congress 2025 in Collaboration with Pfizer
Vysioneer presented clinical trial data in collaboration with Pfizer at the ESMO Congress 2025, with their research on AI-derived early response highlighted in the ESMO Daily Reporter.
2025-10
Vysioneer
VYSIONEER Collaborates with MC Medical to Introduce the First-ever Brain Tumor Auto Contouring AI for Radiotherapy to Japan
Vysioneer announced a collaboration with MC Medical to bring their AI-powered brain tumor auto-contouring solution, VBrain, to Japan for radiotherapy.
2024-01
Princeton Innovation
Startup brings AI technology to measurements of tumor progression - Princeton Innovation
Vysioneer, founded by Princeton alumnus Jen-Tang (JT) Lu, was recognized at the Alumni Startup Challenge for its cutting-edge oncology AI solutions, including VBrain, the first AI tumor auto-contouring tool to receive FDA clearance.
2023-07
PR Newswire
Vysioneer Announces Data Sharing Agreement with Pfizer to Augment Oncology Clinical Trials with Artificial Intelligence
Vysioneer and Pfizer entered a data sharing agreement to apply AI in oncology clinical trials, aiming to improve drug efficacy assessment and explore advanced biomarkers.
2023-02
PMC (PubMed Central)
Stratified assessment of an FDA-cleared deep learning algorithm for automated detection and contouring of metastatic brain tumors in stereotactic radiosurgery - PMC
This study validated Vysioneer's VBrain, an FDA-cleared deep learning algorithm, for its promising results in segmenting brain metastases in patients treated with stereotactic radiosurgery.
2023-04
Imaging Technology News
Vysioneer Receives FDA Clearance on First-Ever Tumor Auto-Contouring Solution for Radiation Therapy
Vysioneer received FDA clearance for VBrain, the first AI-powered tumor auto-contouring solution for radiation therapy, which enhances precision and efficiency in treating brain tumors.
2021-04
Neuro-Oncology
Randomized multi-reader evaluation of automated detection and segmentation of brain tumors in stereotactic radiosurgery with deep neural networks | Neuro-Oncology | Oxford Academic
A study published in Neuro-Oncology demonstrated that Vysioneer's AI-based assistive tool, VBrain, increased inter-clinician agreement, improved tumor detection, and shortened contouring time in SRS workflows.
2021-03

Frequently Asked Questions

Vysioneer's flagship product is VBrain, an FDA-cleared, AI-powered solution for brain tumor auto-contouring. VBrain significantly improves clinical workflows and treatment accuracy for brain radiosurgery and radiotherapy by automating the contouring process for common brain tumors, which traditionally takes several hours, down to a few minutes.
VBrain is specifically designed to auto-contour the three most common types of brain tumors: brain metastasis, meningioma, and acoustic neuroma. Clinical findings indicate that VBrain assistance leads to a 12.2% higher sensitivity for lesion detection and decreases treatment planning time by a median of 30.8%.
Yes, Vysioneer's VBrain received FDA clearance in 2021, marking it as the first AI device cleared for tumor auto-contouring in radiation therapy. This regulatory approval underscores its safety and efficacy for clinical use.
Vysioneer's AI platform provides lesion-level insights, enabling a more granular evaluation of drug efficacy in clinical trials, going beyond traditional patient-level data. This allows pharmaceutical companies, such as Pfizer, to make earlier and more confident decisions by analyzing individual tumor responses and predicting long-term outcomes like progression-free survival.
Vysioneer has established strategic partnerships with leading institutions and companies, including National Taiwan University Hospital, Stanford Cancer Institute, Pfizer, GE Healthcare, and MC Medical in Japan. These collaborations demonstrate strong market adoption, clinical validation, and a commitment to expanding their AI solutions globally, indicating robust company stability.
Vysioneer's AI goes beyond traditional patient-level assessments by analyzing individual tumors within a patient, providing detailed lesion-level insights. This capability helps clinicians and pharmaceutical companies understand tumor heterogeneity and predict treatment outcomes more accurately, supporting personalized treatment strategies.
While specific details on pricing and support structures require direct inquiry, Vysioneer emphasizes seamless integration of its AI solutions, such as VBrain, into existing clinical workflows. VBrain is designed to be vendor-neutral, supporting data routing to and from DICOM nodes within a hospital network, and the company offers contact channels for support.

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