Zephyr Sleep Technologies
About Zephyr Sleep Technologies
Zephyr Sleep Technologies was a healthcare AI company that developed FDA-approved, cloud-connected medical devices for the diagnosis and treatment of sleep-disordered breathing, primarily obstructive sleep apnea (OSA). Their flagship product, MATRx plus, was an at-home Class II medical device designed to perform both a standard home sleep test (HST) and an oral appliance trial.
The MATRx plus system leveraged proprietary algorithms, artificial intelligence, and machine learning to identify patients who would be suitable for oral appliance therapy and to recommend an optimal mandibular position for treatment. This technology aimed to reduce the high failure rates historically associated with oral appliance therapy for OSA. The device offered real-time, cloud connectivity, enabling seamless collaboration among dental professionals, sleep physicians, and Zephyr’s servers for comprehensive patient management.
Unfortunately, Zephyr Sleep Technologies ceased operations on June 25, 2021. The company cited the significant impact of the COVID-19 pandemic on the dental services and products industry, coupled with unsuccessful efforts to raise additional equity capital, as the reasons for its closure.
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What Physicians Need to Know
It is important for physicians to be aware that Zephyr Sleep Technologies ceased operations on June 25, 2021, due to the impact of the COVID-19 pandemic and unsuccessful efforts to secure additional funding. While their MATRx plus system offered innovative solutions for OSA diagnosis and oral appliance therapy planning, the company is no longer operational. Therefore, new prescriptions or reliance on their services for ongoing patient management are not possible. Physicians who previously utilized Zephyr's technology may need to explore alternative solutions for patient selection and oral appliance titration.
Prior to its closure, Zephyr Sleep Technologies had partnered with Dentsply Sirona to integrate the MATRx plus into a 'Simple Sleep Solution,' combining 3D imaging, SICAT Air software, and OPTISLEEP appliances for a comprehensive 3D solution for OSA analysis and treatment. This partnership aimed to create a digital workflow for dental practitioners. However, given Zephyr's cessation of operations, the direct integration and support for the MATRx plus system are no longer available. Any existing integrations would be legacy and not actively supported by Zephyr.
What the Web Says
Zephyr Sleep Technologies was a company that developed medical devices for diagnosing and treating sleep-disordered breathing, notably the MATRx and MATRx plus systems. The company ceased operations on June 25, 2021, due to the impact of the COVID-19 pandemic on the dental services and products industry and an inability to raise additional equity capital. Prior to its closure, employee reviews indicated a generally positive workplace culture, though some concerns about management and job security were raised. Product reviews for their MATRx plus device highlighted its innovative technology for identifying suitable candidates for oral appliance therapy and simplifying the treatment process for dental professionals.
Overall: NegativeStrengths
- Cutting-edge technology for sleep apnea diagnosis and treatment
- MATRx plus simplifies workflow for dental professionals
- MATRx plus offers real-time cloud connectivity for collaboration among health professionals
- Positive workplace culture and respectful environment (prior to closure)
- Flexible work environment (prior to closure)
- Product was considered unique in its capabilities
Limitations
- Company ceased operations in June 2021
- Poor leadership team cited by some employees (prior to closure)
- Low job security and advancement opportunities (prior to closure)
- Product price was a barrier for some (prior to closure)
- Some employees hoped to never hear of the company again (prior to closure)
- Management paid on unknown criteria, not performance or merit (prior to closure)
Based on reviews from: Indeed.com, Sleep Review, Capterra, Reddit, G2
Last updated: 2026-07-19
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