Cleerly ISCHEMIA vs ClearRead CT

Similar category, different focus. These tools serve overlapping but distinct needs. Comparability 65/100 Comparability is an AI-graded 0–100 score of how directly these two tools compete — higher means a more apples-to-apples comparison.
by Cleerly
VS
by Riverain Technologies

AI Verdict

Cleerly ISCHEMIA is designed for detailed non-invasive assessment of coronary artery ischemia, plaque characteristics, and stenosis severity using CCTA scans. ClearRead CT, while also addressing cardiothoracic health, primarily focuses on enhancing pulmonary nodule detection and offers coronary artery calcification scoring from CT scans. Therefore, while both utilize AI for CT analysis in cardiology, their core applications and specific diagnostic outputs are distinct.

Choose Cleerly ISCHEMIA if…

Choose Cleerly ISCHEMIA if your primary goal is to non-invasively assess the likelihood of coronary artery ischemia at a vessel level and characterize coronary plaque burden using CCTA scans. This tool is ideal for cardiologists seeking detailed insights into myocardial perfusion and plaque morphology to inform personalized treatment strategies for heart disease.

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Choose ClearRead CT if…

Choose ClearRead CT if your focus is on enhancing the detection, characterization, and tracking of pulmonary nodules, or for efficient coronary artery calcification scoring on ungated, non-contrast CT scans. This solution is particularly beneficial for radiologists and pulmonologists aiming to improve diagnostic accuracy and streamline workflows in lung cancer screening and general cardiothoracic imaging.

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Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Quick Comparison

Feature Cleerly ISCHEMIA ClearRead CT
Pricing Unknown Contact for pricing
Deployment Web-based solution On-premise (stand-alone server, virtual machine) and Cloud
BAA Available Yes AI-estimated Unknown
FDA Status Cleared AI-estimated Cleared AI-estimated
HIPAA Yes AI-estimated Unknown

Head-to-Head

AI-generated assessment across six dimensions based on each tool's documented features and compliance posture. Grounded in public data — not a substitute for hands-on evaluation.

Usability

ClearRead CT

ClearRead CT emphasizes seamless PACS integration and vendor-neutral processing, allowing radiologists to remain within their native reading environment, which is a significant workflow advantage. User testimonials confirm easy installation and integration, contributing to faster reading times without requiring additional workstations or logins. Cleerly ISCHEMIA offers a web-based platform with interactive reports, which is user-friendly, but ClearRead CT's deep integration into existing radiology workflows provides a more streamlined experience for its target users.

Clinical Value

Cleerly ISCHEMIA

Cleerly ISCHEMIA provides a comprehensive, prognostic assessment of coronary artery disease by non-invasively determining ischemia likelihood at a vessel level, estimating FFR, and characterizing coronary plaque. It has been validated in multiple clinical trials, demonstrating higher diagnostic accuracy and prognostic utility for major adverse cardiovascular events (MACE) compared to other non-invasive methods. While ClearRead CT offers significant value in pulmonary nodule detection and CAC scoring, Cleerly's detailed, prognostic insights into CAD can more directly guide definitive treatment decisions and has a Category I CPT code for reimbursement.

Pricing & Value

Cleerly ISCHEMIA

Neither tool provides transparent pricing, making a direct cost comparison impossible. However, Cleerly ISCHEMIA has secured a Category I CPTu00ae code (75580) for its non-invasive FFR estimation, which signifies established reimbursement pathways and a clearer financial value proposition for providers. This established reimbursement mechanism significantly de-risks the financial investment for healthcare institutions. ClearRead CT does not publicly list similar Category I CPT codes for its primary features.

Enterprise Readiness

ClearRead CT

ClearRead CT demonstrates strong enterprise readiness through its flexible deployment options (on-premise and cloud), vendor-neutral PACS integration, and extensive adoption in over 100 VA sites and globally in 20+ countries. It is also ISO27001 certified and supports role-based authentication. While Cleerly ISCHEMIA is HIPAA compliant and FDA-cleared with API integration, ClearRead CT's proven large-scale deployment across diverse enterprise environments and explicit security certifications suggest a broader and more robust readiness for complex healthcare systems.

Innovation

Cleerly ISCHEMIA

Cleerly ISCHEMIA's innovation lies in its ability to non-invasively estimate fractional flow reserve (FFR) and provide comprehensive, prognostic characterization of coronary plaque from a standard CCTA scan. This '3-in-1' approach for atherosclerosis, stenosis, and ischemia, with its prognostic value for MACE, represents a significant advancement in guiding cardiac care and potentially reducing the need for invasive procedures. While ClearRead CT's patented vessel suppression and automated nodule tracking are innovative for pulmonary imaging, Cleerly's holistic and prognostic approach to CAD diagnosis offers a more transformative impact on patient management.

Support & Docs

ClearRead CT

Riverain Technologies provides a comprehensive support framework for ClearRead CT, including dedicated customer care via email and phone with specified hours, a support ticket system, FAQs, system requirements, workflow guides, and manuals. This detailed offering of resources and direct contact options indicates a robust and accessible support structure. Cleerly also states a commitment to customer success and offers various resources, but ClearRead CT's explicit breakdown of support services appears more extensive.

Feature-by-Feature

Detail beyond the Quick Comparison summary. For pricing, deployment, BAA, FDA, and HIPAA see the Overview tab.

Feature Cleerly ISCHEMIA ClearRead CT
Name Cleerly ISCHEMIA ClearRead CT
Company Cleerly RIVERAIN TECHNOLOGIES
Description Cleerly ISCHEMIA is an FDA-cleared AI tool that analyzes CCTA scans to non-invasively determine the likelihood of coronary artery ischemia at a vessel level, aiding physicians in personalized diagnosis and treatment planning for heart disease. ClearRead CT is an FDA-cleared AI suite by Riverain Technologies for cardiothoracic health, enhancing pulmonary nodule detection and coronary artery calcification analysis in CT scans. It improves diagnostic accuracy, reduces reading times, and streamlines radiology workflows through advanced AI and vessel suppression technology.
Key Features AI-enabled CCTA analysis, Non-invasive fractional flow reserve (FFR) estimation, Vessel-level ischemia likelihood determination, Coronary plaque characterization (volume, type, location), Stenosis severity assessment, 3D digital models of coronary arteries, Comprehensive interactive web-based reports, Integration with PowerScribe via API Pulmonary Nodule Detection (solid, part-solid, ground glass), Patented Vessel Suppression (Clear Visual Intelligence), Nodule Characterization and Measurement (volume, diameter, location, type, depth), Automated Nodule Tracking and Comparison to Prior Exams, Coronary Artery Calcification (CAC) Scoring (ungated, non-contrast CTs), Reduced Reading Time (up to 36%), Improved Detection Accuracy (29% reduction in missed actionable nodules), Seamless PACS Integration / Vendor-neutral processing
Specialties Cardiology, Radiology Cardiology, Pulmonology, Radiology

Videos

Demos, reviews, and walkthroughs featuring Cleerly ISCHEMIA and ClearRead CT.

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Frequently Asked Questions

Cleerly ISCHEMIA is an AI tool specifically designed to analyze CCTA scans to non-invasively determine the likelihood of coronary artery ischemia at a vessel level, aiding in personalized diagnosis and treatment planning for heart disease. ClearRead CT, conversely, is an AI suite that enhances pulmonary nodule detection and performs coronary artery calcification (CAC) analysis in CT scans, focusing on cardiothoracic health and improving diagnostic accuracy for lung abnormalities.
Cleerly ISCHEMIA provides detailed CCTA analysis, including non-invasive fractional flow reserve (FFR) estimation, vessel-level ischemia likelihood, coronary plaque characterization (volume, type, location), and stenosis severity assessment. ClearRead CT offers coronary artery calcification (CAC) scoring, specifically from ungated, non-contrast CTs, as part of its broader cardiothoracic health suite, but does not focus on ischemia or detailed plaque characterization.
While both tools are relevant to Cardiology and Radiology, ClearRead CT uniquely extends its support to Pulmonology, primarily through its advanced pulmonary nodule detection, characterization, and tracking features. Cleerly ISCHEMIA is solely focused on cardiology and radiology for comprehensive heart disease diagnosis and management.
Cleerly ISCHEMIA offers integration with PowerScribe via an API for comprehensive interactive web-based reports. ClearRead CT provides seamless PACS integration and vendor-neutral processing, with output provided in DICOM format, allowing for review alongside original or vessel-suppressed series.
Yes, both tools provide quantitative data. Cleerly ISCHEMIA offers non-invasive FFR estimation, vessel-level ischemia likelihood, and detailed coronary plaque characterization and stenosis assessment. ClearRead CT provides nodule characterization and measurement (volume, diameter, location, type, depth), automated nodule tracking, and coronary artery calcification (CAC) scoring.

Backers

Who funded each tool's parent company.

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