eCARTv5 Clinical Deterioration Suite (“eCART”) vs Etiometry

Direct competitors — feature-level head-to-head below. Comparability 85/100 Comparability is an AI-graded 0–100 score of how directly these two tools compete — higher means a more apples-to-apples comparison.

AI Verdict

Both AgileMD's eCARTv5 and Etiometry offer FDA-cleared, AI-powered clinical decision support for high-acuity care, focusing on early detection of patient deterioration and clinical pathway automation. While eCARTv5 specifically predicts death or ICU transfer in hospitalized adult patients using up to 97 variables, Etiometry provides broader physiologic insights and risk analytics (e.g., IDO2, IVCO2) across various critical care settings. The choice between them may depend on the specific patient population and the desired depth of physiological insights versus a more generalized deterioration prediction.

Choose eCARTv5 Clinical Deterioration Suite (“eCART”) if…

Choose eCARTv5 Clinical Deterioration Suite if your primary goal is to leverage an FDA-cleared, AI-powered early warning system that continuously assesses and predicts the risk of clinical deterioration (death or ICU transfer) in hospitalized adult patients. This tool is ideal for hospitals seeking to integrate real-time risk stratification and embedded clinical pathways directly into their EHR system, aiming to minimize false alarms and reduce clinician workload while improving patient outcomes across various medical conditions.

View eCARTv5 Clinical Deterioration Suite (“eCART”) →

Choose Etiometry if…

Choose Etiometry if your focus is on gaining deep physiologic insights and automating hospital-defined clinical pathways, particularly within high-acuity care settings like the ICU, OR, and ED. This platform is well-suited for organizations looking to aggregate and visualize real-time physiologic data from diverse sources, utilize FDA-cleared risk analytics (e.g., IDO2, IVCO2, ACD, HLA), and drive quality improvement initiatives through automated workflows and comprehensive clinical databases.

View Etiometry →

When considering AI tools for high-acuity care, both AgileMD’s eCARTv5 Clinical Deterioration Suite and Etiometry offer robust solutions, each with distinct strengths. eCART excels at continuously assessing and predicting the risk of clinical deterioration (death or ICU transfer) in hospitalized adult patients, integrating directly with EHRs to provide real-time risk stratification and embedded clinical pathways. Its core strength lies in its early warning system, designed to alert clinicians hours before critical illness, while minimizing false alarms. This makes eCART particularly well-suited for hospital medicine and critical care teams focused on proactive intervention and standardized care guidance across a broad patient population.

Etiometry, conversely, specializes in delivering deep physiologic insights and supporting the automation of hospital-defined clinical pathways, primarily in high-acuity settings like anesthesiology, critical care, and emergency medicine. Its key practical difference is its emphasis on comprehensive data aggregation and visualization from various sources, providing a holistic, vendor-neutral view of patient physiology. Etiometry’s FDA-cleared risk analytics, such as IDO2 and IVCO2, offer specific, data-driven insights for proactive and personalized care escalation or de-escalation. Physicians prioritizing a deep dive into real-time physiologic data and the automation of highly customized clinical pathways within specialized high-acuity environments may find Etiometry to be the more appropriate choice.

Ultimately, the decision hinges on the primary need: if the goal is a broad, continuous assessment of deterioration risk with integrated clinical pathways for general hospitalized adults, eCART is a strong contender. If the focus is on granular physiologic insights, comprehensive data aggregation, and the automation of specialized clinical pathways in high-acuity care, Etiometry offers a more tailored solution.

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Quick Comparison

Feature eCARTv5 Clinical Deterioration Suite (“eCART”) Etiometry
Pricing Contact vendor for tailored quote. Contact for pricing
Deployment Cloud-based SaaS, integrated directly into Electronic Health Record (EHR) systems. Hybrid (On-premise, Cloud-based)
FDA Status 1 AI-estimated 1 AI-estimated
HIPAA Unknown Yes AI-estimated

Head-to-Head

AI-generated assessment across six dimensions based on each tool's documented features and compliance posture. Grounded in public data — not a substitute for hands-on evaluation.

Usability

Etiometry

Etiometry has strong evidence of positive user experience, with 88% of nurses reporting that the platform makes their job easier and helps them complete tasks in fewer steps. It is also described as easy to use and helps streamline communication and charting. While AgileMD is praised for its intuitive interface and user-friendly design, specific metrics on user satisfaction are not as readily available.

Clinical Value

Etiometry

Both tools are FDA-cleared and aim to improve patient outcomes. Etiometry, however, has a broader range of FDA-cleared risk analytics (IDO2, IVCO2, ACD, HLA) and a more extensive evidence base with over 150 studies, demonstrating reductions in ICU length of stay, ventilation time, and readmissions. AgileMD's eCARTv5 has shown strong performance in predicting clinical deterioration and has undergone retrospective and prospective validation.

Pricing & Value

Tie

Both companies state that pricing is available upon contacting the vendor for a tailored quote, indicating a lack of public pricing transparency. While Etiometry has published an economic impact analysis suggesting a significant ROI and annual savings for hospitals, AgileMD also highlights cost efficiency through reduced unnecessary tests and procedures. Without specific pricing details for either, it's difficult to definitively declare a winner in terms of overall value.

Enterprise Readiness

Etiometry

Both tools are HIPAA compliant and FDA cleared, indicating a strong foundation for enterprise use. Etiometry offers a hybrid deployment model (on-premise, cloud-based) which can be more flexible for large enterprises with varying IT infrastructures. Etiometry also has 10 FDA clearances and is used in over 175 ICUs across more than 50 hospitals, demonstrating widespread adoption and scalability. AgileMD is cloud-based SaaS and integrates directly with EHRs, with over 400 hospitals and 150,000 clinical users.

Innovation

Etiometry

Both tools leverage AI for clinical decision support. Etiometry stands out with its development of multiple FDA-cleared, model-based risk algorithms for various physiological insights, including non-invasive prediction of carbon dioxide retention in neonates. Etiometry also has a cardiogenic shock tool that supports institution-defined classification within clinical pathways. AgileMD's eCARTv5 utilizes a gradient-boosted machine-learning model for early warning, which is also innovative.

Support & Docs

Tie

Both companies encourage direct contact for support and provide resources like documentation and training. Etiometry's implementation process has been described as straightforward with responsive support, and minimal ongoing IT workload. AgileMD also offers various training resources and support channels including email, phone, chat, and a knowledge base. Without more detailed comparative information on the breadth and depth of their documentation and support services, it's a tie.

Feature-by-Feature

Detail beyond the Quick Comparison summary. For pricing, deployment, BAA, FDA, and HIPAA see the Overview tab.

Feature eCARTv5 Clinical Deterioration Suite (“eCART”) Etiometry
Name eCARTv5 Clinical Deterioration Suite (u201ceCARTu201d) Etiometry
Company AgileMD Etiometry
Tagline AI-powered clinical decision support for better healthcare outcomes and efficiency. Clinical Intelligence for High-Acuity Care Teams
Description AgileMD's eCARTv5 Clinical Deterioration Suite is an FDA-cleared, AI-powered Software as a Medical Device (SaMD) that integrates with EHRs to continuously assess and predict the risk of clinical deterioration (death or ICU transfer) in hospitalized adult patients, guiding care with embedded clinical pathways. Etiometryu2019s platform delivers deep physiologic insights and supports the automation of hospital defined clinical pathwaysu2014enabling clinicians to make timely decisions and actions that may improve outcomes, reduce costs, and ease the burden on care teams.
Key Features AI-powered clinical deterioration prediction; Continuous patient risk assessment (death or ICU transfer); EHR integration with real-time data (up to 97 variables); Embedded clinical pathways for care guidance; Early warning system (alerts hours before critical illness); Risk stratification (eCART score and risk designation); Minimizes false alarms and clinician workload; Reporting and benchmarking capabilities Data Aggregation & Visualization (Holistic view, vendor-neutral); FDA-Cleared Risk Analytics (IDO2, IVCO2, ACD, HLA); Clinical Pathway Automation; Quality Improvement Application/Clinical Database; AI-driven clinical intelligence; Real-time physiologic data aggregation; Early deterioration identification; Proactive & personalized care escalation/de-escalation
Specialties Critical Care, Emergency Medicine, Hospital Medicine Anesthesiology, Critical Care, Emergency Medicine

Videos

Demos, reviews, and walkthroughs featuring eCARTv5 Clinical Deterioration Suite (“eCART”) and Etiometry.

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Frequently Asked Questions

eCARTv5 integrates directly into EHR systems, analyzing up to 97 real-time variables including vital signs, lab results, and nursing assessments to generate a risk score and guide care with embedded clinical pathways. Etiometry also integrates with major EHR systems like Epic and Cerner, providing single sign-on, ingesting medication, I/O, observations, and order sets, and offering real-time visualization tools to support bedside decision-making and interdisciplinary communication.
eCARTv5 demonstrated an AUROC of 0.834 in retrospective validation and 0.828 in prospective validation for predicting clinical deterioration (death or ICU transfer). At a moderate-risk threshold, it had a sensitivity of 51.8% and a positive predictive value (PPV) of 9.0%, while at a high-risk threshold, the PPV increased to 14.2% with a sensitivity of 38.6%. Etiometry's platform utilizes FDA-cleared risk analytics algorithms, such as IDO2, IVCO2, and HLA, which continuously ingest patient data to detect deterioration.
eCARTv5 is designed for hospitalized adult patients across various medical and surgical wards, with validated performance across diverse patient demographics and clinical conditions, including COVID-19, sepsis, and heart failure. Etiometry is primarily focused on high-acuity care settings like ICUs, and has expanded its evidence base to include adult critical care, with specific applications in cardiac surgery, circulatory support, and ventilation management.
Etiometry provides implementation specialists who work with hospital IT teams for server setup, software installation, and maintenance, as well as clinical specialists who train hospital staff on all shifts and consult on adapting the platform to meet site-specific needs. Etiometry's platform is described as intuitive and easy to use, with multiple views adaptable to different clinical situations. Information regarding eCARTv5's specific training and learning curve was not available in the provided data.
Etiometry's Quality Improvement Application (QI App) provides long-term storage and accessibility of clinical data for research, quality improvement, and reporting initiatives, including automated reports for tracking clinical performance and events like mechanical ventilation. eCARTv5 includes reporting and benchmarking capabilities that allow hospital teams to evaluate their performance and create more productive practice patterns.
Etiometry's platform is designed to support standardized care by automating workflows aligned with hospital-specific clinical guidelines and has been deployed across over 175 ICUs in 50+ hospitals. eCARTv5 has been validated retrospectively in a geographically diverse set of health systems and prospectively across 21 hospitals from three health systems, suggesting its applicability for multi-site deployments.
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