ARC Innovation Center

ARC Innovation Center is Sheba Medical Center’s flagship venture engine, structured to accelerate the global deployment of clinical AI, medical devices, and telemedicine through international hospital partnerships. The structural advantage is unusual: ARC is housed inside one of the largest and most internationally connected hospitals in the world, which gives portfolio companies real-world validation environments and pathways into other hospital systems globally. For physician founders, that hospital integration is operationally meaningful in a way that few investors can match.

The thesis concentrates on digital health, clinical AI, and medical devices that can be deployed inside Sheba and then exported to other hospital systems through ARC’s international partnership network. The incubator engages with founders who want to integrate their products into clinical environments early, validate them with real patients and clinicians, and use that validation to accelerate commercial deployment elsewhere. The portfolio is not deeply public, but the operating pattern is consistent.

Check sizes sit in the 250 thousand to 1 million dollar range, consistent with an incubator and seed positioning. Stage focus is firmly at the start: pre-seed and seed, with the expectation that follow-on capital will come from Israeli healthtech-specialist funds and international Series A investors once the company has matured. Geography is Israel-anchored, with the international hospital network providing United States and global pathways.

The team is built around clinicians, technologists, and innovation-program operators embedded inside Sheba, which is the structural advantage. Diligence is built around the clinical-fit value proposition as much as the standard venture process.

Approach ARC when you are a physician or technical founder with a clinical AI tool, a medical device, or a telemedicine product that would genuinely benefit from hospital integration and international deployment. Pure consumer-wellness or unregulated software plays will be a worse fit. The most direct path in is through Sheba clinicians, ARC’s innovation programs, or other ARC portfolio founders. Time the conversation when you have a working product or prototype, a clinical-validation plan, and a willingness to engage with the hospital environment as a development partner. Founders should plan for a substantive engagement with the clinical organization rather than a hands-off check.