City of Hope Ventures

City of Hope Ventures is the strategic investment arm of City of Hope, a comprehensive cancer center in Duarte, California. The fund focuses on accelerating commercialization of novel oncology therapies and life science technologies, with sub-vertical attention to biotech and pharma therapeutics. AI is not a stated focus.

The fund invests at seed and Series A with $1M to $5M checks. Its strategic value is access to oncology clinical expertise, translational research capabilities, and a major cancer treatment infrastructure. U.S. companies developing oncology assets are the clearest fit, particularly those with potential to engage City of Hope as a clinical or research partner.

Founders should approach with a defined oncology asset, scientific rationale, and a credible development plan. The most effective entry points are usually through clinical investigators or technology transfer relationships at City of Hope, rather than cold venture outreach. Expect diligence to weigh both venture metrics and how the company could leverage the institution’s translational footprint. Limited public information is available about deal cadence and portfolio composition.