ExSight Ventures

VC New York, United States · Founded 2014

ExSight Ventures is a returns-oriented, mission-focused life sciences venture capital firm specializing in early-stage investments in innovative ophthalmic diagnostic and treatment solutions. They leverage deep domain expertise and capital-efficient techniques to identify and support breakthrough technologies addressing vision diseases.

About ExSight Ventures

ExSight Ventures is a specialist early-stage venture firm focused on ophthalmology and vision-related health, with a portfolio orientation that includes therapeutics, diagnostics, and surgical devices for eye disease. The narrow vertical focus is the firm’s defining feature; this is a clinical-domain investor, not a generalist healthtech fund. Healthcare exposure is total within ophthalmology; founders building outside that vertical should not approach. AI focus is selective and clinically grounded; the firm will fund AI-enabled diagnostics, retinal imaging, and decision-support tools where the science holds up and there is a credible regulatory and reimbursement path, but it is not an AI-thesis investor. Stage is typically Seed through Series B with checks plausibly in the USD 1M to USD 5M range, often syndicated with strategic ophthalmology investors and corporate venture arms of the major eye-care players. This is the wrong door for any founder outside vision and eye health, for general digital health, or for AI infrastructure teams. It is a strong fit for early ophthalmology teams that benefit from a scientifically literate partner with deep relationships among retinal specialists, KOLs, eye-care strategics, and the FDA division relevant to ophthalmic products. Entry path is a warm introduction from an ophthalmology KOL, a portfolio CEO, or a co-investing specialist fund; the firm’s narrow focus means cold outreach with on-thesis, scientifically rigorous decks does receive attention when the work is genuine. Bring real clinical data and a clear reimbursement story.

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Team

James C. Murray, J.D.
Co-founder and Partner
Dr. Michael Nissen
Partner
Dr. Firas M. Rahhal
Partner
Mr. Adam Benowitz
Founding Partner
Mr. Alan M. Spiro
Partner

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Last updated 2026-05-06. Sourced from this fund's published materials.
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