Monochrome Capital

Monochrome Capital is a US early-stage venture firm associated with founder Karan Mehandru and a thesis oriented around enterprise software, vertical SaaS, and category-leading software companies. The firm’s footprint is consistent with a focused early-stage fund running concentrated bets rather than a high-velocity index strategy. Healthcare exposure is selective rather than central; expect interest in healthcare software companies that are fundamentally enterprise SaaS plays with strong unit economics, vertical depth, and scalable go-to-market motions, rather than care-delivery, regulated devices, or therapeutics. AI focus is real and applied, particularly when AI is core to a vertical SaaS moat. Stage is typically Series A and selective Seed, with check sizes plausibly in the USD 3M to USD 10M range as part of a syndicate, occasionally leading. This is the wrong door for therapeutics, medical devices, biotech, or healthcare services that depend on payor and regulatory navigation rather than software economics. It is a strong fit for healthcare software founders who have already shipped a product, achieved early revenue traction, and are positioning for a Series A with a software-style growth profile. Entry path is a warm introduction from a portfolio CEO, a co-investing seed fund, or a senior enterprise-software operator; founders should bring retention, expansion, and pipeline metrics rather than a sector thesis.