Plug & Play Ventures

VC Sunnyvale, United States · Founded 2006

Plug and Play Ventures invests globally in early-stage, technology-driven healthcare and life sciences startups, leveraging its massive corporate partner network to accelerate pilot programs and commercial distribution.

About Plug & Play Ventures

Plug & Play Ventures is the venture investment arm of Plug and Play Tech Center, a Silicon Valley-based global accelerator and corporate-innovation platform that runs vertical-specific programs including a substantial health and insurtech track. The investment vehicle typically writes small initial checks (often $25K to $250K) alongside accelerator participation, with the differentiated value being corporate connectivity, pilot pathways with the platform’s extensive Fortune 500 partner network, and exposure across the global accelerator footprint. For healthcare founders, Plug and Play is most relevant if you are at the seed or pre-seed stage and would benefit from structured corporate introductions to large health systems, payers, pharma companies and medical device manufacturers participating in the program, particularly if you are open to participating in their accelerator cohort. The firm is a poor fit as a lead investor in any competitive seed or Series A round at scale, and is not well-suited for therapeutics, regulated devices and diagnostics that require deep scientific or regulatory partnership. Founders should evaluate the time commitment of accelerator participation against the realistic value of corporate introductions; quality varies significantly by partner and by founder fit with the program. Entry is via the open accelerator application process for the health track, supplemented by direct outreach to Plug and Play health team principals via LinkedIn. Founders should clarify check size, equity terms, program duration, location requirements, named corporate partners relevant to their thesis, and follow-on capital pathways before committing.

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Healthcare AI tools backed by Plug & Play Ventures

Tools made by companies in Plug & Play Ventures's portfolio that we cover in the directory.

AlgoSurg
AlgoSurg Inc.
Radiology & Imaging AI
AlgoSurg provides AI-powered cloud-based solutions for 3D surgical planning, patient-specific instrument design, and robotic surgery enhancement, primarily for orthopedic and cardiovascular procedures. It accelerates workflows for medical device OEMs, robotic systems, and 3D printing providers by automating surgical planning and generating 3D models from CT/MRI scans.
CharmHealth EHR
CharmHealth
Patient Engagement & Education
CharmHealth offers an AI-powered, cloud-based EHR system with an integrated AI Copilot designed to ease documentation burden, simplify workflows, and answer questions for care teams.
Hyfe
Hyfe
Drug Discovery & Research
Hyfe offers an advanced acoustic AI system for detecting and monitoring cough, establishing it as a routinely measured biomarker and endpoint for clinical research and respiratory care.
Caresyntax Data-Driven Surgical Intelligence
Caresyntax
Clinical Decision Support & Reference
Caresyntax is a vendor-neutral, enterprise-grade surgical intelligence platform that uses AI-powered software to analyze large volumes of clinical, operational, and financial data to provide actionable insights and improve patient outcomes and operational efficiency.

Portfolio companies in our directory

Other portfolio companies

Companies in Plug & Play Ventures's portfolio not currently in our directory.

Team

Saeed Amidi
Founder & CEO
LinkedIn
Alireza Masrour
General Partner, Investments
LinkedIn
Jojo Flores
Co-Founder
LinkedIn

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Last updated 2026-05-06. Sourced from this fund's published materials.
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