Unorthodox Ventures

VC Austin, United States · Founded 2017

Unorthodox Ventures invests in early-stage medical technology and physical product companies, operating as a permanent capital vehicle with a single LP. The firm leverages its deep engineering, manufacturing, and marketing expertise to help startups scale and navigate entry into the U.S. market.

About Unorthodox Ventures

Unorthodox Ventures is a US-based investment platform at unorthodoxventures.com with a Crunchbase and LinkedIn presence, positioned as a non-traditional capital partner that historically combines venture investing with operating support and brand-building services. Without explicit stage or sector data in the input, the firm is best understood as a generalist that values founder quality and category-creating ideas rather than a healthcare specialist. The brand-led approach typically maps best onto consumer brands, direct-to-consumer healthcare products, and lifestyle health categories rather than clinical infrastructure, regulated devices, or B2B payer software. For healthcare AI founders, this means the relevance window is narrow but real: consumer health AI, women’s health, mental health, sleep, longevity, and wellness brands with strong storytelling and retention metrics are credible candidates. Anyone building enterprise EHR-integrated software, clinical decision support for hospitals, or therapeutic discovery platforms should look at sector specialists instead. Check sizes for a platform like this typically span USD 500K to USD 3M at seed, with selective participation in larger rounds. Geographic preference skews to US-based companies. Best entry path is a warm introduction through a consumer ecosystem connector or a portfolio founder, supplemented by a direct LinkedIn message to the managing partner with a tight narrative on brand, traction, and why your category is underserved by traditional venture. Bring DTC metrics, brand-building proof points, and retention curves rather than enterprise pipeline maps to the first conversation.

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Healthcare AI tools backed by Unorthodox Ventures

Tools made by companies in Unorthodox Ventures's portfolio that we cover in the directory.

ArteraAI Prostate
Artera
Oncology AI
ArteraAI Prostate is an AI-powered diagnostic test that provides prognostic and predictive insights for localized prostate cancer, aiding in personalized treatment decisions and improving patient outcomes.
Artera (formerly WELL Health)
Artera
Patient Engagement & Education
Artera (formerly WELL Health) provides a unified communication hub for health systems, sitting on top of existing EHR systems to automate workflows, send appointment reminders, and collect patient feedback. The platform aims to deliver the best experience to patients and healthcare staff through seamless, integrated communications, allowing patients to manage healthcare communications from one recognizable phone number and staff to reduce busy work.

Portfolio companies in our directory

Other portfolio companies

Companies in Unorthodox Ventures's portfolio not currently in our directory.

Team

Carey Smith
Founding Contrarian
Yechiel (Ben) Lanzkron
Deal Team
Lewis Kilongo
Deal Team
Cuinn Alexander
Deal Team
Daniel Allen
Deal Team
Rachel Nelson
Deal Team

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Last updated 2026-05-06. Sourced from this fund's published materials.
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