100Plus RPM

by Connect America (powered by 100Plus)  · Based in United States → — Better Remote Care for Better Patient Outcomes. Be more connected to your patients. Connect them to longer, healthier lives.
Family Medicine Geriatrics Internal Medicine

Revenue-sharing model based on medicare reimbursement

Overview

100Plus RPM (by Connect America) is an end-to-end remote patient monitoring and chronic care management (CCM) platform designed to help healthcare providers track patient health metrics between office visits. The platform is primarily utilized by primary care practices, cardiologists, and multi-specialty clinics managing patients with chronic conditions such as hypertension, diabetes, and congestive heart failure.

The platform fits into clinical workflows by handling the administrative and operational burdens of remote care. The 100Plus clinical team acts as an extension of the practice, managing patient outreach, onboarding, device setup, and education. Incoming physiological data is monitored continuously, and the system alerts the practice to significant changes in patient vitals. The platform also integrates with Electronic Health Records (EHR) to streamline billing, simplify claims, and automatically generate reports on billable codes.

Notable Capabilities:

  • AI Virtual Health Assistant (Esper): An interactive, patient-facing AI assistant that sends automated reminders, educational content, and encouragement to support patient adherence and consistent device usage.
  • Turnkey Device Logistics: Cellular-enabled devices are shipped directly to patients pre-configured, eliminating the need for home Wi-Fi setup or smartphone pairing.
  • Comprehensive Reporting Portal: A centralized dashboard for clinicians to study data patterns, receive notifications, and access structured reports.
  • Patient Portal & SDOH Surveys: A secure portal allowing patients to track their own health trends and complete Social Determinants of Health (SDOH) surveys to provide deeper clinical context.

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Key Features

  • AI Virtual Health Assistant (Esper/Ava) for patient engagement and education via SMS
  • Cellularly-connected RPM devices (blood pressure cuff, blood glucose monitor, digital weight scale, pulse oximeter, thermometer)
  • Automated health data collection and real-time alerts for out-of-range readings
  • EHR Integration with major systems (e.g., AdvancedMD, DrChrono, athenahealth, Epic, NextGen, Practice Fusion)
  • Automated billing support and claim generation for Medicare reimbursement
  • Dedicated clinical care team for data monitoring and patient check-ins
  • Patient outreach, enrollment, device setup, and white-glove onboarding services
  • Secure patient portal with multi-factor authentication for health trend review
  • Comprehensive reporting and analytics dashboard for patient insights
  • Telemedicine module for appointment scheduling and telehealth visits

Use Cases

  • Chronic disease management (e.g., hypertension, diabetes, CHF, obesity)
  • Remote Patient Monitoring (RPM) for continuous health data collection
  • Chronic Care Management (CCM) for ongoing patient support
  • Reducing hospitalizations and readmission rates
  • Improving patient adherence and engagement with care plans
  • Streamlining practice workflows and reducing administrative burden

What Physicians Need to Know

Scheduling Optimization
The AI virtual health assistant, Ava/Esper, coordinates patient appointment scheduling and reminders, and the telemedicine module supports doctors in scheduling and conducting online consultations.
Staff Management Features
100Plus reduces administrative burden by handling patient outreach, device setup, engagement, education, and automated claim generation. A dedicated clinical team of licensed nurses and medical assistants acts as an extension of the practice, monitoring data, conducting check-ins, and reporting on billable codes, allowing practice staff to focus on patient care.
Patient Flow Analytics
The provider portal delivers real-time patient health data and automatic alerts for out-of-range readings. Physicians can track historical patient data to identify patterns, and the platform offers an outcomes data summary for the entire RPM patient population, including longitudinal analysis of physiologic metrics.
Multi-Location Support
As a web-based platform, 100Plus is accessible online anytime, inherently supporting providers and patients across various geographical locations and practices in multiple states.
Financial Dashboard
The platform provides automated claim generation and billing functionality for Medicare reimbursement, including tracking time spent monitoring patients to meet billing requirements. It helps practices maximize reimbursement for RPM and CCM services and offers tailored reimbursement estimates.
Referral Management
The AI assistant, Ava/Esper, assists in coordinating physician referrals and the platform helps identify eligible patients for RPM and CCM programs.
Quality Metrics Tracking
100Plus tracks key health metrics such as blood pressure, blood glucose, and weight, demonstrating significant improvements in these areas. The provider portal offers summaries of individual and system-wide performance on health metrics, supporting quality improvement initiatives and informed clinical decisions.
Compliance Reporting
The platform is HIPAA compliant and assists practices in meeting Medicare review requirements for reimbursement. It includes automated reporting on billable codes and streamlines patient adherence to care plans.
Physician Tip

To maximize the benefits of 100Plus RPM, physicians should leverage the AI assistant (Ava/Esper) for patient engagement, reminders, and education to enhance adherence and free up staff time. Utilize the comprehensive reporting and alert system to proactively identify at-risk patients and intervene early, thereby reducing episodic care. Delegate administrative tasks like patient enrollment, device setup, and initial data monitoring to 100Plus's full-service clinical team to optimize practice workflow and allow staff to focus on direct patient care. Finally, understand the billing and reimbursement mechanisms for RPM and CCM to maximize practice revenue while improving patient outcomes.

100Plus offers EHR integration to securely incorporate patient data into electronic health records, aiming to streamline billing processes and reduce administrative burden. The platform has a notable partnership with athenahealth through its Marketplace program, making its RPM services readily available to athenahealth users.

Details

Category Practice Management & Scheduling
Pricing Revenue-sharing model based on medicare reimbursement
  • Devices are provided at no cost to eligible Medicare patients and practices
  • Providers are reimbursed by Medicare for services, including initial setup (approx
  • $20 one-time), device supply and data collection (approx
  • $55/month per patient), and clinical staff time for monitoring and interactive communication (approx
  • $60/month per patient for 20 minutes)
DeploymentCloud-based
Compliance
BAA AvailableUnknown AI-estimated
HIPAA CompliantUnknown AI-estimated
FDA Status Unknown AI-estimated

RPM devices used with the 100Plus platform must meet the FDA definition of a medical device. CMS guidelines for billing RPM do not explicitly require FDA registration or clearance, but devices must automatically upload patient measurements.

Integrations
EHR Not specified
Specialties Family Medicine, Geriatrics, Internal Medicine

What the Web Says

100Plus RPM is a remote patient monitoring platform that provides cellular-based, ready-to-use RPM devices to patients, allowing physicians to receive real-time health data and automatic alerts. The platform aims to simplify chronic disease management and has shown statistically significant improvements in patient health metrics like blood pressure, blood glucose, and weight loss. It also includes features like a telemedicine module, billing functionality for Medicare reimbursement, and an AI-powered virtual medical assistant named Ava.

Overall: Mixed

Strengths

  • Delivers cellular-based, ready-to-use RPM devices to patients.
  • Provides real-time patient health data and automatic health alerts to physicians.
  • Demonstrated significant reductions in blood pressure, blood glucose, and weight loss.
  • Offers an end-to-end solution including patient outreach, device setup, engagement, education, and automated claim generation.
  • Utilizes AI (Ava, a virtual medical assistant) to improve patient engagement and outcomes.
  • Helps reduce hospitalizations and other forms of high acuity care.

Limitations

  • Some users reported issues with inaccurate device readings and being charged for unused devices.
  • Concerns about over-billing and poor customer service have been raised.
  • Patients may need to be trained on using the equipment, contrary to initial expectations.
  • Lack of transparency in pricing, requiring direct contact for a tailored quote.
  • Limited public buyer reviews, suggesting a need for more customer references and trials.
  • Potential for patients to be responsible for 20% of the cost, which can be a concern for cost-sensitive populations.

Based on reviews from: GetApp UK, PR Newswire, Capterra, Software Advice, 100Plus (White Paper), Healthcare Digital, Connect America, RankedVendors, Reddit, Slashdot

Last updated: 2026-07-25

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Press & Coverage

100Plus
New CPT Codes Expand Access to Remote Patient Monitoring - 100Plus
CMS has finalized two new CPT codes (99445 and 99470) for Remote Patient Monitoring (RPM), effective January 1, 2026, which will make RPM services more flexible and accessible. These codes address a long-standing gap in RPM reimbursement by allowing providers to bill for patients who transmit data for as few as 2 to 15 days in a 30-day period, rather than the previous 16-day minimum.
2025-11
100Plus
The Benefits of Remote Patient Monitoring and Chronic Care Management Programs for Patients with Diabetes - 100Plus
A study on the 100Plus RPM platform involving over 31,000 patients demonstrated an average reduction of 9.3 mg/dL in blood glucose for diabetic patients and an average weight loss of 12.1 lbs for patients starting at over 286 lbs. RPM allows for near real-time tracking of glucose levels, enabling healthcare providers to detect changes earlier and intervene promptly.
2024-11
100Plus
How AI-enabled RPM Can Reduce Barriers to Care and Improve Health Outcomes for Rural Communities - 100Plus
The 2024 Final Medicare Physician Fee Schedule, released November 2, 2023, will allow Rural Health Centers (RHCs) and Federally Qualified Health Centers (FQHCs) to receive Medicare reimbursement for telehealth and remote patient monitoring services. AI-enabled RPM can bridge geographic barriers by allowing clinicians to manage patient care outside traditional settings, reducing the need for physical visits, which is particularly beneficial for rural patients.
2023-11
100Plus
The Benefits of EHR Integration for Remote Patient Monitoring - 100Plus
100Plus's RPM solution securely integrates with all major EHRs, including AdvancedMD, Allscripts, Athena, Cerner, Epic, and more, using standard interfaces like FHIR, HL7, and APIs. This integration streamlines workflows, simplifies billing by automatically pushing eligible RPM claims into a practice's EHR as a draft charge, and increases scalability.
2023-08
100Plus
Remote Patient Monitoring Becomes a Game-Changer for Greenville Healthcare Associates - 100Plus
Greenville Healthcare Associates implemented the 100Plus RPM solution for nearly 600 patients, observing significant improvements in clinical health metrics, increased patient engagement, and better compliance with care plans. The results included an average reduction in random blood glucose of 6.0 mg/dl for diabetic patients, a mean weight loss of 3.6 lbs for obese patients, and average blood pressure reductions for hypertensive patients.
2023-05
100Plus
Patient Outcomes Using Remote Patient Monitoring - 100Plus
An analysis of over 30,000 patients across 426 healthcare practices using 100Plus RPM showed significant reductions in blood pressure, blood glucose for diabetics, and weight loss. 94% of healthcare providers reported that 100Plus RPM improved or greatly improved blood pressure control, and 69% reported an improved ability to achieve guideline-directed medical therapy for heart failure.
2023-01
PR Newswire
100Plus Enables Sweetwater Medical Associates to Improve Patient Adherence and Health Metrics with AI-Assisted Remote Patient Monitoring - PR Newswire
Sweetwater Medical Associates improved patient adherence and clinical health metrics using the 100Plus AI-assisted RPM platform, with statistically significant improvements over 180 days. Patients with hypertension saw an average blood pressure reduction of 5.80 mmHg, and obese patients experienced a mean weight loss of 3.45 lbs.
2022-09
PR Newswire
Remote Patient Monitoring Platform 100Plus Powered by Artificial Intelligence Health Assistant Ava Leads to Improved Health Metrics for Senior Adult Patients - PR Newswire
An analysis of over 18,000 Medicare patients using the 100Plus RPM platform, powered by AI health assistant Ava, showed significant reductions in blood pressure, blood glucose for diabetics, and weight loss. The mean systolic blood pressure decreased from 141.0 mmHg to 136.3 mmHg in the first three months, and diabetes patients' random glucose decreased by 7.5 mg/dl.
2021-11

Videos

Product demos, reviews, and walkthroughs for 100Plus RPM.

View all on YouTube

Frequently Asked Questions

100Plus RPM is designed for family care physician practices managing patients with chronic conditions in an outpatient setting, such as hypertension, diabetes, and congestive heart failure. The platform handles patient outreach, consent, device setup, and shipping of pre-configured cellular devices, requiring minimal time from clinicians for enrollment and training. Clinicians then review monthly patient data and alerts through a provider portal, with AI assistants like Ava and Esper engaging patients to promote adherence.
100Plus RPM utilizes standard CPT codes for remote patient monitoring, including 99453 for initial setup, 99454 for device supply and data collection, and 99457/99458 for clinical staff time and interactive communication. While Medicare reimburses for these services, 100Plus operates on a revenue-sharing model, meaning practices receive a reduced net reimbursement after the platform deducts fees for hardware, cellular service, and support. A provider can bill CPT code 99454 once per patient every 30 days, regardless of the number of devices used, and must collect at least 16 days of data within that period.
100Plus RPM offers a no-upfront-cost model for physician practices, covering devices, software, and patient onboarding without initial investment. For patients, there is no charge for devices, test strip refills, or shipping, though a standard co-pay or deductible may apply, which is often covered by secondary insurance. Practices receive approximately $60 per patient per month in reimbursement, but this is a net amount after 100Plus's revenue-sharing deductions.
A significant limitation of 100Plus RPM is its revenue-sharing model, which can substantially reduce the net per-patient income for practices compared to platforms allowing full reimbursement retention. The platform primarily focuses on RPM, with limited support for stacking multiple care management programs like Chronic Care Management (CCM), Principal Care Management (PCM), Behavioral Health Integration (BHI), or Remote Therapeutic Monitoring (RTM). Additionally, its device ecosystem is somewhat limited, offering about six device types and lacking integration for continuous glucose monitors (CGMs) or contactless monitoring solutions.
Compared to alternatives, 100Plus offers a zero-upfront-cost entry barrier and an end-to-end solution with AI virtual assistants for patient engagement and cellular-only devices requiring no patient tech setup. However, competitors like CCN Health may offer higher per-patient revenue by allowing providers to retain full Medicare reimbursement, broader program stacking (RPM, CCM, PCM, BHI, RTM), and a wider range of devices including CGMs and contactless monitoring. Other alternatives such as HealthArc, Prevounce, and Smart Meter also provide comprehensive RPM solutions with varying features, device ecosystems, and pricing models.
Yes, 100Plus RPM maintains compliance with Health Insurance Portability and Accountability Act (HIPAA) regulations, ensuring secure handling of patient data. Regarding billing, only one practitioner can bill for RPM services per patient within a 30-day period, even if multiple devices are used for different conditions. While RPM can be billed in conjunction with Chronic Care Management (CCM) services, the time spent on each service must be separately documented to avoid duplication.

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Suggest an Edit → | Last Verified: 2026-04-24 | First Added: 2026-04-24
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