1up Platform

by 1upHealth  · Based in United States → — Health Data, On Demand
Family Medicine Hospital Medicine Internal Medicine

Volume based pricing
Regulatory Status Disclosed

Overview

1upHealth provides a FHIR-first data platform designed for healthcare interoperability, enabling health plans to acquire, manage, and utilize healthcare data efficiently and securely. The platform aims to modernize health data exchange by addressing challenges such as manual workflows, lagging information, poor data quality, and data silos. It offers solutions for regulatory compliance, improved member experiences, and stronger provider relationships. The 1up Platform, built on a lakehouse architecture, connects and activates health data across the ecosystem at scale.

Beyond compliance, 1upHealth’s offerings power advanced interoperability use cases like risk adjustment, quality management, member engagement, and care management. The company emphasizes a user-centric design approach, conducting interviews, focus groups, and user testing to understand customer needs and build products that provide actionable insights from health data. 1upHealth is committed to security and trust, embedding these principles into its platform development and operations.

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Key Features

  • FHIR-first data platform
  • Automated prior authorization
  • Payer-to-payer data exchange
  • Provider access to patient data
  • Patient access to health information
  • Accurate provider directory
  • Formulary management
  • EHR integrations
  • Real-time patient updates
  • Advanced analytics and AI enablement

Use Cases

  • Meet government regulations (CMS-9115-F, CMS-0057-F, CMS-4208-F2)
  • Automate prior authorization
  • Improve member onboarding and close care gaps through historical member data
  • Enable providers with timely patient data for better care decisions
  • Publish accurate provider directories for easy in-network care discovery
  • Deliver transparent drug coverage details to members and providers

What Physicians Need to Know

Healthcare API Support
1upHealth provides a common RESTful API that fully supports FHIRu00ae Release 4 (R4 version 4.0.1) for interacting with electronic health data, including clinical and claims data. It supports all FHIR R4 resources defined in the HL7 v2 Specification and offers HL7v2-to-FHIR and CCDA-to-FHIR conversion.
HIPAA-Compliant Infrastructure
The 1up Platform is HIPAA compliant and is used by major hospital systems. It aligns with HITRUST r2 and HIPAA requirements, utilizing encryption, role-based access controls, continuous monitoring, and U.S.-based hosting to safeguard sensitive healthcare data. 1upHealth achieved HITRUST i1 Certification for its FHIR Platform in June 2024, demonstrating its commitment to cybersecurity and data protection.
Clinical NLP Capabilities
Information regarding specific Clinical NLP Capabilities is not explicitly detailed in the provided search results. The platform focuses on data exchange and interoperability using FHIR standards.
De-Identification Tools
Specific de-identification tools are not explicitly mentioned in the provided search results. The platform emphasizes secure and compliant exchange of health data.
Sandbox/Testing Environment
1upHealth offers a developer portal where organizations can create sandbox clients to test their applications with synthetic data. Developers can register, create a client, and sync their application to a demo environment for testing connections to a member-facing authentication application.
Rate Limits & Pricing
1upHealth offers volume-based pricing for API queries, with 20,000 free API queries per month. Beyond that, costs range from $0.0049/query for 1-100,000 queries/month to $0.0029/query for over 1,000,001 queries/month. Health system connections are $0.09 per month per connection after the first 10 free connections. Storage is fixed at $0.99 per 100MB, with up to 100MB free. There are also tiered plans for questionnaire automation, starting with a free plan and scaling up to enterprise pricing.
Certification Program
1upHealth achieved HITRUST i1 Certification for its 1up FHIR Platform in June 2024, demonstrating adherence to high standards for cybersecurity and data protection. They aim to achieve HITRUST r2 Certification by 2025. The platform is also SOC2 certified and GDPR compliant.
Physician Tip

For physicians and healthcare providers, 1up Platform's robust FHIR API support and HIPAA-compliant infrastructure mean easier, secure access to comprehensive patient data, including clinical and claims information. This can streamline data exchange with other systems and applications, potentially improving care coordination and reducing administrative burden. The sandbox environment is valuable for testing new applications without impacting live patient data. While specific clinical NLP and comprehensive medical terminology support are not explicitly detailed, the platform's focus on standardized FHIR data exchange lays a strong foundation for integrating tools that offer these capabilities.

1up Platform is designed to integrate with existing data sources, utilization management systems, analytics tools (like Power BI and Tableau), and identity providers. It offers an extensive network with integration with top EHR vendors and supports various data ingestion options including HL7v2-to-FHIR and CCDA-to-FHIR conversion. The platform also supports integrations with communication tools like Slack, Microsoft Teams, and Google Chat for questionnaire automation. Approved third-party applications can access 1upHealth's Health Plan Patient Access API endpoints.

Details

Category Developer Tools & APIs, EMR / EHR Systems, Population Health Analytics
Pricing Volume based pricing
  • Patient Mediated APIs: 1,000 FREE API queries/month; 1-100,000 queries/month = $0.0049/query; 100,001-1,000,000 = $0.0039/query; >1,000,001 = $0.0029/query; Up to 10 connections FREE; $0.09/month/connection; Up to 100 MB FREE storage; $0.99 per 100MB storage; Typically ~$1-2 per patient per year
  • Direct Provider Connections: 20,000 FREE API queries/month; 1-100,000 queries/month = $0.0049/query; 100,001-1,000,000 = $0.0039/query; >1,000,001 = $0.0029/query; Monthly fee based on # of FHIR® resources, $200-450/month per connection; Up to 2GB FREE storage; $0.99 per 100MB storage
DeploymentCloud-based
Compliance
BAA Available Yes AI-estimated
HIPAA Compliant Yes AI-estimated
FDA Status Not applicable AI-estimated — unknown
Integrations
EHR Not specified
Specialties Family Medicine, Hospital Medicine, Internal Medicine

What the Web Says

1up Platform (1up.health) is a healthcare data platform that focuses on efficient health data interchange and interoperability, utilizing the FHIR standard. It provides cloud-based, API-driven solutions for various healthcare organizations, including payers, providers, digital health innovators, and life sciences entities. The platform is praised for its ability to centralize information, automate tasks like RFP responses, and streamline data exchange, leading to increased productivity and improved patient outcomes.

Overall: Positive

Strengths

  • Efficient health data interchange and interoperability using FHIR standard.
  • Centralized information access, reducing time spent searching for data.
  • Automation of tasks like RFP and questionnaire responses, significantly speeding up processes.
  • Ease of use and smooth implementation.
  • Responsive and supportive customer service.
  • Secure and compliant exchange of high-quality, comprehensive, and timely health data.

Limitations

  • Some users found the web interface for responding to and editing questions took some getting used to.
  • The platform is still evolving, with some features noted as coming soon.
  • One review on Reddit for a different product named '1up' (a bike rack) mentioned issues with corrosion and difficult-to-replace parts, as well as unhelpful customer support, but this does not appear to be related to 1up.health.
  • Another Reddit discussion about a '1up' bike rack mentioned the locking mechanism in the hitch coming loose on rough roads and parts needing replacement after five years.
  • Some users of a different 'OneUp' social media scheduling tool experienced laggy mobile versions and occasional website crashes.

Based on reviews from: G2, Slashdot, Elion Health, Indeed.com, Reddit, KLAS Research, Gartner Peer Insights, Capterra

Last updated: 2026-07-27

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Press & Coverage

1upHealth Newsroom
1upHealth Announces 1up Gateway to Simplify CMS-0057-F Compliance for Health Plans
1upHealth introduced the 1up Gateway, a new solution to help health plans comply with the CMS Interoperability and Prior Authorization Final Rule (CMS-0057-F) by providing a managed API and compliance layer for existing FHIR infrastructures.
2026-07
1upHealth Newsroom
Oklahoma's Largest Locally Owned Health Plan Selects 1upHealth
CommunityCare, Oklahoma's largest locally owned health plan, has chosen the 1up Platform and its associated solutions for their interoperability initiatives.
2025-09
ACCESS Newswire
1upHealth Sets a New Standard for Health Data Interoperability
1upHealth launched an enhanced 1up Platform at HIMSS25, featuring a modern lakehouse architecture to provide real-time access to actionable health data for various healthcare stakeholders.
2025-03
1upHealth Blog
The New 1up Platform: Bringing the Power of Lakehouse Architecture to Healthcare
This article details the launch of the v2 1up Platform, highlighting its modern lakehouse architecture and its ability to transform healthcare with real-time health data exchange and analytics.
2025-03
Parsers VC
1up Secures $5.25M to Revolutionize Sales Knowledge Automation
1up, a New York-based startup, secured $5.25 million in seed funding for its AI knowledge automation platform designed to streamline sales processes by providing quick answers to complex sales questions.
2025-01
1upHealth Blog
Powering Electronic Prior Authorization with Integrated Data & AI
This article discusses how payers can leverage FHIR interoperability and AI automation within the 1up Platform to meet regulatory requirements and improve prior authorization processes.
2026-02
1upHealth Newsroom
Health Data Cloud Leader 1upHealth Raises $40 Million Series C led by Sixth Street Growth
1upHealth announced a $40 million Series C funding round, led by Sixth Street Growth, to further develop its FHIR-native platform for interoperability and modern computing, used by over 75 enterprise organizations.
2023-04
PR Newswire
1upHealth Selected by NCQA As Partner in Digital Quality Solutions Pilot
1upHealth was chosen by the National Committee for Quality Assurance (NCQA) to participate in its inaugural Digital Quality Solutions pilot, leveraging its FHIRu00ae data platform for broad-scale interoperability.
2022-06

Videos

Product demos, reviews, and walkthroughs for 1up Platform.

View all on YouTube

Frequently Asked Questions

The 1up Platform prioritizes data security and privacy by adhering to industry standards like HIPAA and FHIR. It employs robust encryption protocols, access controls, and regular security audits to protect sensitive patient information throughout the data lifecycle.
The 1up Platform provides a comprehensive suite of developer tools, including FHIR APIs for standardized data exchange, SDKs for various programming languages, and a developer portal with extensive documentation and tutorials. These resources enable physicians to integrate health data into their applications efficiently.
The 1up Platform is designed with compliance in mind, offering features and guidance to help developers meet regulatory requirements like HIPAA. It provides secure data handling, audit trails, and consent management tools to ensure that applications built on the platform adhere to necessary legal and ethical standards.
The 1up Platform typically offers tiered pricing models that cater to different user needs, from individual developers to large healthcare enterprises. These models often include factors like data volume, API calls, and the number of integrated applications, with detailed information usually available on their official website or through direct inquiry.
While powerful, potential limitations of the 1up Platform could include the learning curve associated with FHIR standards for those new to them, or the need for specific technical expertise to fully leverage advanced customization options. Data integration might also be limited by the availability and quality of data from external sources.
Yes, there are other platforms and tools for healthcare application development. The 1up Platform differentiates itself through its strong focus on FHIR-native API access, comprehensive developer tools, and a robust emphasis on compliance and security, aiming to simplify the complexities of healthcare data integration for developers.
The 1up Platform is designed to facilitate integration with various EHR systems by leveraging FHIR standards. The process typically involves connecting to the EHR's FHIR API (if available) or utilizing 1up's connectors to normalize data from different sources into a standardized FHIR format, making it accessible for applications.

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Suggest an Edit → | Last Verified: 2026-07-26 | First Added: 2026-07-26

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