ActX Genomic Service

by ActX  · Based in United States → — Personalize medical care using genetics
Cardiology Internal Medicine Oncology

Contact for pricing
Regulatory Status Disclosed

Overview

ActX offers real-time genomic decision support integrated into Electronic Health Records (EHRs), fulfilling the promise of widespread personalized medical care based on genetics. It removes the “last mile” barrier that has prevented effective medical use of an individual’s genetics by making genetics an integral part of medical care.

The service automatically checks all prescriptions for efficacy, adverse reactions, and dosing based on the patient’s genetics. It provides a customizable, EHR-integrated, real-time genomic decision solution that can be live in a matter of weeks for health systems.

For providers, ActX offers a practical way to add precision medicine to their practice, including real-time pharmacogenomics, without impacting workflow. Individuals can also learn how their DNA makes them unique and use that information to help their doctor make better decisions about their care. ActX can also provide a professional medical analysis of 23andMe data, adding genetics into the medical chart for comprehensive coverage on medications, risks, and carrier conditions.

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Key Features

  • EHR Integrated Genomic Decision Support
  • Real-time Pharmacogenomics (medication-genome interactions)
  • Automated prescription checking for efficacy, adverse reactions, and dosing
  • Customizable solution for health systems
  • Integration and professional medical analysis of 23andMe data
  • Identification of actionable hereditary risks (e.g., cancer, cardiovascular, metabolic)
  • Carrier status reporting
  • Continuously updated, evidence-based knowledge base
  • Patient mobile app for accessing and sharing genomic profile
  • Saliva-based DNA testing via CLIA-certified lab

Use Cases

  • Personalized prescription management and optimization
  • Proactive identification and management of hereditary disease risks
  • Integration of genetic data into routine clinical workflow for providers
  • Enhancing precision medicine initiatives for health systems
  • Professional interpretation of direct-to-consumer genetic data (e.g., 23andMe)
  • Patient engagement and education on genetic health

What Physicians Need to Know

Key Capabilities
Provides real-time genomic decision support integrated into existing clinical workflows. Offers pharmacogenomics (drug-genome interaction checking), alerts for actionable hereditary risks (e.g., certain cancers, cardiovascular diseases), and carrier screening. The service includes an integrated patient Genomic Profile that is continuously updated with the latest scientific research.
Clinical Utility
Enables personalized medical care by optimizing medication efficacy, reducing the risk of adverse drug reactions, and individualizing dosing based on a patient's genetic profile. Facilitates early interventions and tailored prevention strategies for identified hereditary risks.
Integration Options
Seamlessly integrates with major Electronic Health Records (EHRs) such as Epic, Oracle Health (Cerner), athenahealth, Greenway Health, CompuGroup Medical (CGM APRIMA), Allscripts, eClinicalWorks, NextGen, and Veradigm. It delivers real-time, patient-specific genomic insights and alerts directly within the physician's existing EHR workflow. ActX can import existing genomic data or provide its own saliva-based genetic testing.
Compliance Status
Designed to be HIPAA compliant, ensuring patient privacy and secure handling of genomic data. Genetic testing is performed by a CLIA-certified laboratory.
Pricing Model
Genetic testing is described as affordable and inexpensive. Specific pricing details are not publicly disclosed but are often based on insurance coverage and may be HSA/FSA eligible. Some services may involve an annual fee after an initial trial.
User Experience
Designed for busy clinicians, integrating genomic insights directly into the daily workflow without requiring physicians to be genetics experts. Provides an easily accessible and frequently updated genomic profile within the EHR, with information presented in an easy-to-understand format for patients and a professional version with evidence-based suggested actions for physicians.
Support Quality
Offers support through a dedicated support portal and email. The underlying knowledge base is continuously curated and updated by a team of clinicians, geneticists, genetic counselors, and clinical pharmacists.
Implementation Complexity
Described as having rapid and painless integration, capable of system-wide implementation in weeks. The platform offers flexibility and customization, with a light technical footprint requiring minimal computing resources and no internal storage within the EHR.
Evidence Base
Focuses on actionable genetic risks where clear medical interventions can be taken, supported by a continuously updated knowledge base informed by the latest published evidence and consensus recommendations. For serious non-medication risks, orthogonal testing (Sanger sequencing) is used to confirm variant findings.
Physician Tip

ActX empowers you to seamlessly integrate actionable genomic insights into your daily practice. Leverage the real-time alerts within your EHR for medication prescribing to optimize drug efficacy and avoid adverse reactions. Proactively identify and manage serious hereditary risks and carrier statuses to enable earlier interventions and personalized prevention strategies. Remember that ActX focuses on evidence-based, actionable risks, providing management suggestions and references to support your clinical decisions without requiring you to be a genetics expert. For serious non-medication risks, confirmatory testing by a genetics specialist is recommended.

ActX's strength lies in its deep and real-time integration with a wide array of leading EHR systems, including Epic, Oracle Health (Cerner), athenahealth, and Greenway Health. This allows for automated checking of prescriptions against a patient's genetic profile and direct alerts for actionable genomic risks within your existing clinical workflow. The platform is designed for rapid implementation and can utilize existing patient genomic data or facilitate new saliva-based testing.

Details

Category Pharmacology & Dosing AI
Pricing Contact for pricing
  • Annual fee after free trial for individuals; contact ActX for health systems and practices
  • The service is generally covered by HSA/FSA medical savings accounts
DeploymentEHR integrated (e.g., Epic, Oracle Health, eClinicalWorks), accessible via secure website and mobile app.
Compliance
BAA AvailableUnknown AI-estimated
HIPAA CompliantUnknown AI-estimated
FDA Status Not applicable AI-estimated

ActX is a CAP (College of American Pathologists) accredited Laboratory. Because a physician authorizes the service, FDA approval is not required for its broader interpretation in the U.S.

Integrations
EHR Not specified
Specialties Cardiology, Internal Medicine, Oncology

What the Web Says

ActX Genomic Service integrates actionable genomic insights directly into a clinician's workflow, providing real-time decision support for personalized medicine. It helps physicians tailor treatments, predict medication reactions, and identify hereditary risks based on a patient's genetic profile. The service is designed for busy clinicians and aims to make genomics a practical part of everyday medical care.

Overall: Positive

Strengths

  • Seamless integration with various Electronic Health Records (EHRs) like Epic, athenahealth, Oracle Health (Cerner EHR), Greenway PrimeSUITE, and Veradigm.
  • Provides real-time genomic decision support for medication efficacy, dosing, and potential adverse effects.
  • Identifies actionable genetic risks for conditions like hereditary cancers and cardiovascular diseases, allowing for early intervention.
  • Continuously updates its knowledge base with the latest medical research and reanalyzes patient data, alerting physicians and patients to new findings.
  • Offers affordable saliva-based genetic testing and can also analyze raw data from 23andMe.
  • Results are accessible to both physicians (through EHR) and patients (via a secure website or mobile app).

Limitations

  • Public information on the cost of the service is not readily available, as it's typically billed through insurance.
  • Some users have reported negative experiences with customer service and long waiting times for results.
  • Patients must be affiliated with a doctor to utilize the service.
  • The service is a screening tool and not intended for the diagnosis of high-risk patients, focusing only on selected genetic variants.

Based on reviews from: Nebula Genomics, ActX (works within Epic), athenahealth | athenaConnect, CompuGroup Medical (CGM), ActX (Personalize medical care using genetics), ActX (works within Oracle Health), Greenway Health, DNA Testing Choice, App Store (My ActX Genomic Profile), ActX (Patient Stories), ActX (Personalize medical care using genetics), Altera App Expo, ActX (23andme), DNA Testing Choice (ActX Health Testing Reviews)

Last updated: 2026-08-08

Ratings & Reviews

No reviews yet. Be the first to review this tool!

Rate ActX Genomic Service

Clinical Value
Ease of Use
Integration
Support & Docs
Value for Money

Press & Coverage

ActX
Baptist Health Expands Precision Medicine Effort With ActX
Baptist Health has extended its partnership with ActX until 2028 to expand precision medicine access for its patients and employees, integrating ActX Genomic Decision Support into its Epic EHR across its hospitals and care points.
2023-01
ActX
ActX Laboratory Receives Accreditation from the College of American Pathologists (CAP)
ActX has been awarded accreditation by the College of American Pathologists Accreditation Committee following a recent on-site inspection.
2023-01
ActX
ActX adds personalized, customizable, patient specific recommendations for genetic testing
A new feature in the ActX genomic service now alerts providers if a patient needs genetic testing based on their medications and medical history.
2022-01
ActX
ActX to provide Pharmacogenomic Interpretation for a GUIDE Dementia Care Initiative
ActX has partnered to provide dynamic pharmacogenomic reporting for thousands of patients participating in the GUIDE program, a dementia care initiative.
2022-01
ActX
ActX Expands Genomic Services with New Pharmacogenomic Service Option
ActX has expanded its service offerings with the release of the 'ActX Pharmacogenomic Service' option, catering to patients who prefer to receive only drug-genomic interaction information.
2021-01
Medindia
ActX Adds COVID-19 Susceptibility Assessment to Genomic Screening
ActX has added a new feature to its genomic service that explains a patient's genetic risk for contracting COVID-19, based on current published evidence.
2202-10
ActX
ActX Announces Issuance of U.S. Patent for Real-Time Genomic Decision Support
ActX was issued a U.S. patent for its real-time genomic decision support system, which provides alerts for medication orders and actionable genomic risks.
2020-06
ActX
UCLA Health announces a new pilot project with ActX
UCLA Health is piloting a project with ActX to integrate genomic patient data into its Epic EHR system, aiming to apply precision medicine to a large patient base.
2020-01

Videos

Product demos, reviews, and walkthroughs for ActX Genomic Service.

View all on YouTube

Frequently Asked Questions

ActX integrates real-time genomic decision support directly into EHRs, automatically checking prescribed medications against a patient's genetic profile for potential adverse effects, efficacy, and dosing issues. This system uses an continuously updated, evidence-based knowledge base, curated by a team of clinicians and geneticists, to generate actionable alerts and insights for physicians.
ActX is fully HIPAA compliant and CAP accredited for genomic interpretation, with its laboratory being CLIA-certified. Patient data is secured through end-to-end encryption, sophisticated authentication, and audit procedures, ensuring privacy.
ActX provides a genomic *screening* test that analyzes selected genetic variants for targeted genes, rather than performing whole-genome sequencing. Therefore, a negative result does not definitively rule out all risks, and like all medical tests, false positives and false negatives can occur.
ActX's knowledge base is continuously updated and curated by a diverse team of clinicians, geneticists, genetic counselors, and clinical pharmacists, aiming to provide evidence-based and actionable insights. The focus is on established, actionable genetic risks and drug-gene interactions to guide clinical decisions.
The ActX service includes affordable patient DNA testing, and while specific pricing is not publicly detailed, it is generally paid for by patients. The service can often be covered by HSA/FSA medical savings accounts, though final coverage decisions rest with the plan administrator.
While other genetic testing services exist, ActX differentiates itself by offering real-time genomic decision support seamlessly integrated into various EHRs like Epic, athenaClinicals, and Greenway PrimeSUITE. This integration provides actionable insights directly within the physician's workflow, a key advantage over services that only provide raw genetic data.
ActX is designed for rapid implementation with a light technical footprint, requiring minimal internal storage and processing resources. It integrates with numerous EHRs via an open web service architecture, allowing for system-wide deployment in weeks.

Related Tools

Drugs.com Interaction Checker
Drugs.com
Clinical Decision Support & Reference
Drugs.com offers a comprehensive and freely accessible drug interaction database for clinicians and consumers, checking for interactions with multiple drugs, food, and alcohol. It provides independent, objective, comprehensive, and up-to-date information in a clear and concise format for both consumers and healthcare professionals.
Nirmitee.io Diabetes Care Intelligence
Nirmitee.io
Endocrinology & Metabolic AI
Nirmitee.io Diabetes Care Intelligence is an AI-powered platform that integrates CGM data, analyzes 14-day CGM patterns, and correlates them with insulin doses, meal timing, and activity to generate specific dosing recommendations for personalized diabetes management.
CoverMyMeds Prior Authorization
CoverMyMeds
Pharmacology & Dosing AI
CoverMyMeds provides medication access solutions used by prescribers, clinics, pharmacies, payers, and manufacturers to streamline electronic prior authorization (ePA), verify pharmacy benefits, surface formulary alternatives, and coordinate specialty medication enrollments and patient assistance.
Clair – The AI Clinical Reference Tool
Clair
Clinical Decision Support & Reference
Clair is an AI clinical reference tool that provides healthcare teams with accurate, real-time answers to clinical questions, streamlining decisions on disease states, treatments, and drug interactions.
AXIFI Drug Interaction Checker
AXIFI
Clinical Decision Support & Reference
AXIFI is an AI-powered clinical intelligence platform that provides healthcare practitioners and health members with access to a vast research library, clinical protocols, and AI-driven tools for longevity medicine.
SyncMed
SyncMed
Clinical Decision Support & Reference
SyncMed is an early-stage healthcare AI company with validated technology and government backing, seeking pilot partners and strategic investors to accelerate market adoption of its breakthrough medication reconciliation platform.

See all Pharmacology & Dosing AI tools →

Suggest an Edit → | Last Verified: 2026-05-06 | First Added: 2026-05-06
AI Tool Finder
AI-powered search. Results may not be comprehensive.