AI-Rad Companion Brain MR

by Siemens Medical Solutions U.  · Based in United States → — AI-powered augmented workflow solutions for brain MRI analysis.
Neurology Radiology

Contact for pricing
Regulatory Status Disclosed

Overview

AI-Rad Companion Brain MR is a post-processing image analysis software developed by Siemens Healthineers. It leverages artificial intelligence algorithms to assist clinicians in viewing, analyzing, and evaluating MR brain examinations. The tool automates routine and time-consuming tasks, such as the segmentation of various brain structures and the quantitative analysis of their volumetric properties.

The software automatically identifies approximately 30 brain segments on MRI images, measures their volumes (including gray matter, white matter, and cerebrospinal fluid), and compares these results to a normative reference database. This comparison generates highlighted deviation maps and structured reports, indicating volumetric changes that may be relevant for the diagnosis and management of neurodegenerative diseases like Parkinson’s, Alzheimer’s, and other forms of dementia. Additionally, the AI-Rad Companion Brain MR for Morphometry Analysis, specifically the VA40 version, extends its capabilities to include the quantification and visual assessment of white matter hyperintensities (WMH), providing counts, volumes, and locations. The system supports longitudinal comparison of different timepoints, offering valuable insights into disease progression.

Designed to be seamlessly integrated into existing clinical workflows, AI-Rad Companion Brain MR is DICOM compliant and can transfer results directly to Picture Archiving and Communication Systems (PACS). It operates on the teamplay cloud-based digital health platform, which supports compliance with HIPAA and GDPR, and can be used with MRI scanners from both Siemens Healthineers and other manufacturers. By automating complex measurements and comparisons, the tool aims to reduce radiologists’ workload, increase diagnostic precision, and improve efficiency in interpreting medical images.

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Key Features

  • Automatic segmentation of ~30 brain structures on MRI images
  • Individual volumetric analysis of brain areas (gray matter, white matter, cerebrospinal fluid)
  • Comparison of brain volumes to a normative reference database
  • Automatic generation of highlighted deviation maps for volumetric changes
  • Automatic generation of structured reports with quantitative data
  • White Matter Hyperintensities (WMH) feature (counts, volumes, locations)
  • Longitudinal comparison of different timepoints
  • Seamless integration into existing clinical workflows and PACS
  • DICOM compliant for image and data exchange
  • Cloud-based deployment via teamplay digital health platform

Use Cases

  • Assessment and monitoring of neurodegenerative diseases (e.g., Alzheimer's, Parkinson's, dementia)
  • Evaluating MR brain examinations for volumetric properties of brain structures
  • Quantification and visual assessment of white matter hyperintensities
  • Reducing radiologists' workload by automating routine segmentation and measurement tasks
  • Increasing diagnostic precision and efficiency in interpreting brain MRI studies
  • Supporting differential diagnosis and therapy management in neurology

What Physicians Need to Know

Brain MRI Analysis
AI-Rad Companion Brain MR performs automatic segmentation and individual volumetric analysis of various brain structures based on T1 MPRAGE and T2 FLAIR datasets. It quantifies gray matter, white matter, and cerebrospinal fluid volumes across approximately 30 brain segments.
Neurodegenerative Disease Screening
The tool compares individual brain volumes to a normative reference database (e.g., from ADNI) and automatically generates a highlighted deviation map and structured reports, aiding in the diagnosis and monitoring of neurodegenerative diseases like Parkinson's, Alzheimer's, or other dementias. It also provides analysis of White Matter Hyperintensities (WMH), including counts, volumes, and locations, and supports longitudinal comparison of different time points to monitor changes.
Triage Prioritization Speed
The AI-Rad Companion Brain MR automates routine and repetitive tasks like brain segmentation and volumetric analysis, which were previously performed manually or semi-automatically and were time-consuming. This automation helps to speed up the workflow, with a processing time of 1-10 minutes for analysis.
Mobile Notification System
The AI-Rad Companion with Notifier allows radiologists to review AI results, independent of PACS limitations. While not explicitly a 'mobile' notification system, it facilitates the delivery of results for review.
Physician Tip

AI-Rad Companion Brain MR helps physicians manage workload by automating time-consuming segmentation and volumetric analysis tasks, freeing them to focus on more critical issues. It enhances diagnostic precision by providing objective, quantitative data on brain structure volumes and white matter hyperintensities, compared to normative data, which is crucial for differential diagnosis and therapy management in neurodegenerative diseases. The automatically generated reports with highlighted deviations and longitudinal comparison capabilities support efficient monitoring of disease progression.

The AI-Rad Companion Brain MR seamlessly integrates into existing clinical workflows and is DICOM compliant. Results, including image annotations, reports, and deviation maps, can be automatically transferred to Picture Archiving and Communication Systems (PACS) and can be received directly into reporting templates. It is available on the teamplay cloud-based digital health platform and supports both cloud-based and on-edge deployment options. The software is designed to be used with MRI scanners from Siemens Healthineers and other manufacturers.

Details

Category Neurology AI, Radiology & Imaging AI
Pricing Contact for pricing — Subscription-based software as a service (SaaS) model; contact vendor for specific tiers.
DeploymentCloud-based (via teamplay digital health platform); also supports integration in standard reading environments (PACS).
Compliance
BAA AvailableUnknown AI-estimated
HIPAA CompliantUnknown AI-estimated
FDA Status Yes AI-estimated

The AI-Rad Companion Brain MR for Morphometry Analysis received 510(k) clearance from the U.S. Food and Drug Administration (FDA) around August 2020. The K232305 clearance, dated April 15, 2022, is for an enhancement (VA40) that extends the quantification and visual assessment to white matter hyperintensities.

Integrations
EHR Not specified
Specialties Neurology, Radiology

What the Web Says

The Siemens Healthineers AI-Rad Companion Brain MR for Morphometry Analysis is an AI-powered post-processing software designed to automate the segmentation and volumetric analysis of brain MRI images. It assists clinicians by measuring brain volumes, identifying deviations from normative data, and generating reports, thereby aiming to reduce manual workload and enhance diagnostic efficiency for neurodegenerative disorders like Alzheimer's and Parkinson's disease.

Overall: Positive

Strengths

  • Automates brain segmentation and volumetric analysis, saving radiologists time.
  • Provides quantitative data on brain tissue volumes (gray matter, white matter, cerebrospinal fluid).
  • Compares patient data to age- and sex-matched normative databases, highlighting deviations.
  • Aids in the detection of atrophy in cortical and subcortical regions relevant to dementia diagnosis.
  • FDA cleared, indicating regulatory approval for clinical use.
  • Compatible with MRI scanners from different manufacturers, although it runs on Siemens' cloud-based platform, teamplay.

Limitations

  • Moderate consistency and poor agreement between absolute volumes measured by AI-Rad Companion and FreeSurfer in some studies, though correlation improved after normalization.
  • Standardized measurements can differ significantly from other tools due to variations in normative datasets.
  • Requires integration with Siemens' cloud-based healthcare platform, teamplay.
  • Limited publicly available detailed physician reviews or discussions on platforms like Reddit, G2, or Capterra.
  • Ultimate responsibility for using AI systems in a medical setting lies with physicians, requiring appropriate training and awareness of regulations.
  • Reduced performance of AI systems in the case of small and complex anatomical structures has been reported for AI-based segmentation systems in general, suggesting a need for careful review of AI-generated contours.

Based on reviews from: American Journal of Neuroradiology (via PMC), SelectScience, BioWorld, Cassling, ResearchGate, FDA.gov (via accessdata.fda.gov)

Last updated: 2026-07-20

Ratings & Reviews

No reviews yet. Be the first to review this tool!

Rate AI-Rad Companion Brain MR

Clinical Value
Ease of Use
Integration
Support & Docs
Value for Money

Press & Coverage

Siemens Healthineers
At RSNA, Siemens Healthineers Introduces AI-based MRI Assistants
Siemens Healthineers unveiled two AI-based software assistants, including AI-Rad Companion Brain MR for Morphometry Analysis, at RSNA 2019, designed to streamline routine tasks for radiologists during MRI examinations.
2019-12
Medical Device Network
Siemens Healthineers to introduce AI-based software for MRI - Medical Device Network
Siemens Healthineers announced the debut of its AI-Rad Companion Brain MR for Morphometry Analysis at RSNA 2019, aiming to assist radiologists by automating brain segmentation and volume measurement in MRI images.
2019-12
BioWorld
FDA clears AI-based MRI interpretation tools - Bioworld
The U.S. FDA granted clearance for Siemens Healthineers' AI-Rad Companion Brain MR for Morphometry Analysis, providing radiologists with AI tools to aid in interpreting brain MRI studies.
2020-08
Imaging Technology News
FDA Clears AI-based MRI Interpretation Assistants from Siemens Healthineers
The FDA cleared two new AI-based software assistants from Siemens Healthineers, including AI-Rad Companion Brain MR for Morphometry Analysis, which automates brain segmentation and volume measurement from MRI images.
2020-08
Diagnostic Imaging
FDA Clears Two Siemens Healthineers AI-Based MRI Interpretation Tools
Siemens Healthineers received 510(k) clearance from the FDA for its AI-Rad Companion Brain MR for Morphometry Analysis, an AI-based software that segments brain MRI images and measures brain volume.
2020-08
Siemens Healthineers
AI-Rad Companion Brain MR for morphometry analysis
AI-Rad Companion Brain MR assists clinicians by providing automatic segmentation and quantitative analysis of individual brain structures from MR images, comparing them to normative data.
unknown
American Journal of Neuroradiology
Validity Assessment of an Automated Brain Morphometry Tool for Patients with De Novo Memory Symptoms | American Journal of Neuroradiology
A study published in the American Journal of Neuroradiology assessed the validity of the AI-Rad Companion brain MR imaging tool, finding it reliably detects atrophy in cortical and subcortical regions relevant to dementia diagnosis.
2023-03
Medical Design Briefs
Inside the OEM: Siemens Healthineers - Medical Design Briefs
An article discussing Siemens Healthineers' AI-based products highlights the AI-Rad Companion Brain MR for Morphometry Analysis as a tool that automatically segments brain MRI images and measures brain volume to assist neurologists.
2023-05

Videos

Product demos, reviews, and walkthroughs for AI-Rad Companion Brain MR.

View all on YouTube

Frequently Asked Questions

AI-Rad Companion Brain MR is a post-processing image analysis software that automatically segments and quantifies volumetric properties of various brain structures from T1 MPRAGE and T2 FLAIR datasets. It compares these volumes to a normative database, highlights deviations, and generates a structured report that can be directly archived in your Picture Archiving and Communication System (PACS), seamlessly integrating into the existing clinical workflow.
Yes, AI-Rad Companion Brain MR is FDA cleared and CE-marked, indicating its regulatory compliance for medical use. It is cloud-based and utilizes the certified, secure teamplay infrastructure, which is compliant with HIPAA (Health Information Portability and Accountability Act) in the USA and EU GDPR (General Data Protection Regulation).
While AI-Rad Companion Brain MR provides valuable quantitative data and assists in identifying volumetric changes, it is intended as a supportive tool and its output should be considered by radiologists before making a final diagnosis. Studies have shown varying degrees of correlation and agreement with other segmentation software, and its sensitivity for certain findings can decrease with higher confidence scores.
Yes, there are other AI-powered neuroimaging tools available, such as icobrain, NeuroQuant, and e-ASPECTS, which also automate quantification and analysis of brain structures for neurodegenerative conditions. AI-Rad Companion Brain MR differentiates itself by offering automatic segmentation of over 30 brain regions, comparing them to a normative database, and generating a highlighted deviation map, aiming to save radiologists' time and provide objective, quantitative data.
AI-Rad Companion Brain MR is available through a subscription-based Software as a Service (SaaS) model after an initial 90-day trial license. Installation and use of the teamplay digital health platform are prerequisites for its operation. Specific pricing details are typically obtained by contacting Siemens Healthineers directly.
AI-Rad Companion Brain MR aims to improve efficiency by automating tasks that were previously manual or semi-automatic, providing automatic segmentation and quantitative analysis of individual brain structures. Studies comparing it to tools like FreeSurfer have shown strong correlations, moderate consistency, and high specificity in detecting volumetric abnormalities, though standardized measurements may differ due to varying normative datasets.
AI-Rad Companion Brain MR operates on the cloud-based teamplay digital health platform, which is designed to be compliant with strict data privacy regulations such as HIPAA and GDPR. This secure infrastructure ensures that patient data is handled and protected according to established healthcare standards.

Related Tools

Cercare Medical Oncology Virtual Expert
Cercare Medical
Neurology AI
Cercare Medical's Oncology Virtual Expert is an AI-powered brain tumor segmentation module that provides fast, consistent, and semi-automated tumor analysis from standard MRI data, designed for on-premise deployment within existing clinical radiology workflows.
CoLumbo C-Spine
Smart Soft Healthcare AD
Clinical Decision Support & Reference
CoLumbo C-Spine is an AI-powered software that processes and analyzes cervical spine MRI exams, assisting clinicians in diagnosis and assessment.
MeRT System
Wave Neuroscience
Mental & Behavioral Health AI
MeRT (Magnetic e-Resonance Therapy) is an advanced, personalized form of TMS that uses your own brainwave data to guide treatment. It's a non-invasive, drug-free option designed to help the brain communicate more efficiently so symptoms of conditions like depression, anxiety, PTSD, TBI, autism, and more can improve.
Brainomix 360 Hyperdensity
Brainomix Limited
Neurology AI
Brainomix 360 Hyperdensity is an AI-powered neuroimaging software tool that detects and quantifies brain hyperdensities on CT scans, forming a crucial part of the Brainomix 360 Stroke platform for rapid and accurate stroke assessment.
SOMNUM
HoneyNaps
Clinical Decision Support & Reference
SOMNUM is an AI-enabled medical software tool by Honeynaps Co., Ltd. that provides comprehensive sleep analysis to aid in the diagnosis and management of sleep disorders.
DETECT-ME/CFS project
DETECT-ME/CFS project (ME/CFS Research Foundation)
Clinical Decision Support & Reference
The DETECT-ME/CFS project is developing an AI-supported clinical decision support system to improve the rapid and reliable diagnosis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.

See all Neurology AI tools →

More from Siemens Medical Solutions U.

AI-Rad Companion (Cardiovascular)
Siemens Medical Solutions U.
Cardiology AI
AI-Rad Companion (Cardiovascular) is an AI-powered image processing software by Siemens Healthineers that provides quantitative and qualitative analysis of CT DICOM images to support physicians in evaluating cardiovascular diseases.

View company profile →

Suggest an Edit → | Last Verified: 2026-04-21 | First Added: 2026-04-21
AI Tool Finder
AI-powered search. Results may not be comprehensive.