AliveCor QT Service

by AliveCor  · Based in United States → — Instant, accurate QT interval measurement for enhanced cardiac safety and informed clinical decision-making.
Cardiology Emergency Medicine Internal Medicine

Contact vendor for pricing details.
Regulatory Status Disclosed

Overview

The AliveCor QT Service (often utilized via the InstantQT software and K1000 or KardiaMobile 6L devices) is a point-of-care cardiac safety solution designed to measure and monitor QT and corrected QT (QTc) intervals in seconds. By utilizing AI-enabled, machine learning-powered ECG sensors, the service allows healthcare professionals to evaluate patients for potentially dangerous changes in cardiac activity without requiring a traditional, complex 12-lead ECG setup.

This service is primarily designed for:

  • Psychiatrists and Mental Health Professionals: To screen and monitor patients prescribed psychotropic medications known to cause QT prolongation.
  • Oncologists and Infectious Disease Specialists: To manage cardiac safety for patients on therapies with known cardiotoxic or QT-prolonging side effects.
  • Clinical Trial Sponsors and Biopharma Partners: To integrate decentralized cardiac safety monitoring and real-world evidence collection into drug development pipelines.

In a clinical workflow, the service eliminates the need for external cardiology referrals for routine QT screening. Clinicians or patients can capture a medical-grade, 6-lead ECG in 30 seconds. The integrated software instantly processes the rhythm, calculates the QTc interval, and flags potential prolongations. This rapid assessment supports immediate clinical decision-making, accelerates therapy starts, and enhances patient safety during ongoing medication titration.

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Key Features

  • Cloud-based Software as a Medical Device (SaMD)
  • Measures QT and QTc intervals (Bazett's and Fridericia's formulas)
  • Analyzes ECGs from AliveCor 6-Lead ambulatory ECG devices (e.g., KardiaMobile 6L)
  • Prescription (Rx) use only, for qualified healthcare professionals
  • Utilizes AI and deep neural networks for ECG analysis
  • Provides instant QT measurements (as InstantQT)
  • Integrates with KardiaStation app and KardiaPro portal
  • API available for integration with EHR, SDK, CRM, EDC, and PSP platforms
  • Secure, unlimited cloud storage for ECG data
  • Supports remote ECG recording and monitoring

Use Cases

  • Screening for QT prolongation before prescribing or titrating QT-prolonging medications (e.g., antipsychotics, certain antibiotics, cancer therapies)
  • Monitoring cardiac safety in clinical trials and drug development
  • Identifying patients at risk for Torsades de Pointes (TdP) and sudden cardiac death
  • Supporting rapid clinical decision-making at the point of care
  • Remote patient monitoring of cardiac health
  • Integration into existing practice workflows and EHR systems

What Physicians Need to Know

ECG/EKG Analysis Capability
The AliveCor QT Service (InstantQT) analyzes 30-second electrocardiograms (ECGs) from AliveCor's 6-Lead ambulatory ECG devices (KardiaMobile 6L) to accurately compute QT and heart-rate corrected QT (QTc) intervals. It utilizes deep neural networks and algorithms for ECG noise filtering and RR-interval calculation, specifically for ECGs identified as Normal Sinus Rhythm by KardiaAI. The KardiaMobile 6L also provides instant detection of Atrial Fibrillation, Bradycardia, Tachycardia, Sinus Rhythm with Supraventricular Ectopy, Sinus Rhythm with Premature Ventricular Contractions, Sinus Rhythm with Wide QRS, and Normal Heart Rhythm.
Arrhythmia Detection Accuracy
The KardiaMobile 6L, integral to the QT Service, offers instant detection of common arrhythmias including Atrial Fibrillation, Bradycardia, Tachycardia, Sinus Rhythm with Supraventricular Ectopy, Sinus Rhythm with Premature Ventricular Contractions, Sinus Rhythm with Wide QRS, and Normal Heart Rhythm. Studies have shown high accuracy, with one indicating 96.6% sensitivity and 94% specificity for the Kardia algorithm in AFib detection compared to expert cardiology over-read of simultaneous 12-lead EKGs. Another study found KardiaMobile 6L superior to single-lead devices for AFib detection (99%/97% sensitivity) and double the accuracy for atrial flutter.
Heart Failure Risk Prediction
While the service primarily focuses on QT interval measurement and arrhythmia detection, it indirectly addresses heart failure risk by identifying QT prolongation, which is associated with an increased risk of sudden cardiac death and Torsades de Pointes, a potentially fatal arrhythmia.
Cardiac Monitoring Integration
The AliveCor QT Service is designed for seamless integration with AliveCor's KardiaMobile 6L device. ECG data is securely stored and can be integrated into existing practice workflows via the KardiaPro web-based portal, or through EHR integration, SDK, and API options. AliveCor supports integration with leading EHR software and cardiac information management systems, such as GE Healthcare's MUSEu2122 NX.
AHA/ACC Guideline Alignment
The service aligns with regulatory recommendations from agencies like the FDA and EMA for QT interval assessment in drug safety evaluations. The KardiaMobile 6L device is FDA-cleared for QTc interval measurement. The utility of the service is also referenced in the context of guidelines like the American Psychiatric Association (APA) Resource Document on QTc Prolongation & Psychotropic Medications.
Real-Time Alert Capability
The InstantQT service enables physicians to record and evaluate ECGs for potentially dangerous changes in cardiac activity, such as QT prolongation, in less than one minute, providing instant access to feedback and results. This rapid analysis supports timely clinical decision-making.
Physician Tip

Utilize AliveCor QT Service for rapid, in-office or remote assessment of QT/QTc intervals, especially when prescribing or titrating QT-prolonging medications to mitigate the risk of Torsades de Pointes. The KardiaMobile 6L device offers a convenient, less intrusive method for ECG recording compared to traditional 12-lead ECGs, improving patient comfort and compliance. Leverage its arrhythmia detection capabilities for early identification of common cardiac rhythm abnormalities. Integrate the service with existing EHR systems via KardiaPro for streamlined data management and enhanced patient monitoring.

AliveCor QT Service integrates with the KardiaMobile 6L device for ECG acquisition. Data can be managed through the KardiaPro web portal and offers robust integration options including EHR integration, SDKs for mobile app developers, and APIs for seamless data import into various enterprise systems. This facilitates automated ECG data transfer, secure storage, and workflow efficiency within clinical practices.

Details

Category Cardiology AI, Pharmacology & Dosing AI
Pricing Contact vendor for pricing details.
DeploymentCloud-based (Software as a Medical Device). Accessed over the internet.
Compliance
BAA AvailableUnknown AI-estimated
HIPAA CompliantUnknown AI-estimated
FDA Status 1 AI-estimated

The AliveCor QT Service received FDA 510(k) clearance (K212662) on April 26, 2022. It is cleared as a cloud-based Software as a Medical Device (SaMD) to measure QT and QTc intervals from AliveCor-designed 6-Lead ambulatory ECG devices for prescription use by qualified healthcare professionals.

Integrations
EHR Not specified
Specialties Cardiology, Emergency Medicine, Internal Medicine

What the Web Says

The AliveCor QT Service, utilizing the KardiaMobile 6L device, offers a portable and efficient solution for QT interval screening, particularly beneficial for patients on QT-prolonging medications. It aims to streamline the process of obtaining ECGs in-office, potentially reducing treatment delays and improving patient outcomes. While generally praised for its ease of use and accuracy in detecting certain arrhythmias, some users and healthcare professionals have raised concerns about its limitations compared to a 12-lead ECG, potential for false positives, and customer service issues.

Overall: Mixed

Strengths

  • Easy to use and portable, making it convenient for in-office or at-home use.
  • Provides rapid detection of abnormal QTc intervals and various arrhythmias like atrial fibrillation, bradycardia, and tachycardia.
  • Can reduce the need for frequent conventional 12-lead ECGs, especially in resource-limited settings, saving time and costs.
  • Offers a clinician ECG review service by board-certified cardiologists for detailed analysis within 24 hours.
  • Helps in monitoring patients on QT-prolonging medications, potentially preventing dangerous side effects.
  • Integration options with EHR and a web-based portal (KardiaPro) for managing patient data.

Limitations

  • Does not replace a 12-lead ECG and may miss certain cardiac events or conditions like heart attacks.
  • Can be prone to artifact and may not always provide a clear reading.
  • Some users report issues with device reliability, connectivity, and battery life.
  • Customer service has been a significant concern for some users, with reports of unresponsiveness and difficulty with returns.
  • The intermittent nature of the device may not be sufficient for detecting all paroxysmal or silent arrhythmias.
  • Subscription required for full access to features and detailed arrhythmia detection beyond basic AFib screening.

Based on reviews from: AliveCor, Fierce Biotech, YouTube (iMedicalApps Editor and Physician Cardiologist Satish Misra), iMedicalApps, JAMAnetwork.com, NCBI (National Center for Biotechnology Information), Trustpilot, Mayo Clinic, PMC (PubMed Central), The Skeptical Cardiologist, Best Buy, Reddit, WorthEPenny, Natural Rhythm Nutrition

Last updated: 2026-07-17

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Press & Coverage

Innolitics
Command Line as a Medical Device (CLaMD)
This article discusses the concept of 'Command Line as a Medical Device' and references AliveCor QT Service as a cloud-based service accessed via a REST-based API, without a direct user interface. It highlights how such software can simplify FDA clearance by shifting display and interaction risks to other cleared devices.
2025-05
ComputerTalk For The Pharmacist
Three AI-Enabled Medical Devices Approved by the FDA | ComputerTalk For The Pharmacist
This article highlights the FDA approval of AliveCor QT Service in 2021 for QT prolongation detection, utilizing AI algorithms trained on a large dataset of ECGs from the KardiaMobile 6L device. It emphasizes the importance of detecting prolonged QT intervals due to its association with serious arrhythmias.
2023-10
ResearchGate
Digital Health Trends 2024
This report on Digital Health Trends 2024 lists AliveCor Kardia AI & AliveCor QT Service among various AI-enabled medical devices. It provides an overview of the digital health market, including consumer apps, digital therapeutics, and provider-focused solutions.
2024-12
Innolitics
AliveCor QT Service (K212662) u2014 FDA 510(k)
This entry provides detailed regulatory information regarding the FDA 510(k) clearance for AliveCor QT Service (K212662). It outlines the indications for use, device description as a cloud-based Software as a Medical Device (SaMD), and its intended use by qualified healthcare professionals.
2022-05
Orthogonal
SaMD Cleared by the FDA: The Ultimate Running List - Orthogonal
This comprehensive list of Software as a Medical Devices (SaMD) cleared by the FDA includes AliveCor QT Service, noting its clearance date as April 26, 2022, and its cardiovascular application.
2024-10
Physician AI Tools
AliveCor QT Service vs HealthCCSng - Physician AI Tools
This comparison highlights AliveCor QT Service's capabilities in providing instant, accurate QT and QTc interval measurements from AliveCor 6-Lead ECGs for cardiac safety assessment and medication prescribing decisions. It also notes its enterprise readiness with explicit integration capabilities.
unknown
Physician AI Tools
AliveCor QT Service vs VX1+ - Physician AI Tools
This article compares AliveCor QT Service with VX1+, emphasizing AliveCor's focus on cardiac safety assessment through precise QT/QTc interval measurements from ambulatory ECGs, leveraging AI for analysis. It also points out AliveCor's robust support ecosystem.
unknown
Physician AI Tools
AliveCor QT Service vs ASSURE Wearable ECG - Physician Ai Tools
This comparison highlights AliveCor QT Service's innovation in leveraging AI and deep neural networks for instant, accurate QT/QTc measurements, crucial for drug safety. It also notes its clear enterprise readiness with API availability for various healthcare platforms.
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Videos

Product demos, reviews, and walkthroughs for AliveCor QT Service.

View all on YouTube

Frequently Asked Questions

AliveCor's InstantQTu2122 service employs FDA-cleared, AI-powered ECG processing software to quickly and accurately measure QT intervals, providing instant feedback on QTc values at the point of care. This AI-driven analysis assists healthcare professionals in detecting potentially dangerous QT prolongations, but the physician's clinical judgment remains essential for determining the appropriate course of treatment and conducting a comprehensive risk-benefit analysis.
AliveCor has received 510(k) clearance from the U.S. FDA for healthcare professionals to use the KardiaMobile 6L device to calculate patients' QTc interval, with the InstantQT service utilizing FDA-cleared ECG processing software. The company ensures HIPAA compliance through stringent data security and compliance practices, also holding SOC2 Type 1 and Type 2 attestations, ISO 27001, and ISO 42001 certifications for its AI Management System.
While studies demonstrate good agreement between AliveCor's mobile ECG and traditional 12-lead ECGs for QTc measurement, one study noted the device underestimated QTc in a majority of cases compared to 12-lead readouts. Physicians should be aware that, like all AI-driven tools, potential biases in data gathering and the need for interpretability of AI models are general considerations in clinical integration. The AI serves as an assistive tool, and clinical expertise is vital for comprehensive patient care and decision-making.
The AliveCor QT Service, utilizing the KardiaMobile 6L and InstantQT, offers a fast and convenient method for QTc measurement, often completing an ECG in 30 seconds, which is quicker than traditional 12-lead ECGs. Studies indicate good agreement and accuracy in QTc measurements when compared to standard 12-lead ECGs, proving its utility for early detection of QT prolongation. Its portability and ease of use facilitate remote monitoring and can streamline clinical workflows, potentially reducing treatment delays.
While consumer-facing subscriptions like KardiaCare or Premium are priced at $13.99 USD monthly, specific pricing for healthcare providers for the AliveCor QT Service is not explicitly detailed in the provided information. However, AliveCor offers Patient Engagement Solutions and cardiac monitoring services for healthcare providers that include reimbursable options and integration with existing CPT monitoring codes. Providers are advised to consult AliveCor directly for detailed professional pricing models, which may include subscription or per-use fees tailored to clinical settings.
AliveCor prioritizes data security and privacy, adhering to HIPAA compliance and holding SOC2 Type 1 and Type 2 attestations. They also maintain ISO 27001 certification and ISO 42001 for their Artificial Intelligence Management System, ensuring responsible AI practices. Patient data is securely stored, and the system is designed with 'Privacy by Design' principles to comply with various data privacy laws, including GDPR and PDPL.

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Suggest an Edit → | Last Verified: 2026-04-17 | First Added: 2026-04-17

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