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Antidote Match

by Antidote · Based in United States → — Where patients meet research.

Family Medicine Internal Medicine Oncology

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Overview

Antidote Match is a smart search engine platform that uses AI and structured data to efficiently match eligible patients with appropriate clinical studies, reducing recruitment burden for both patients and researchers. It aims to bridge the gap between medical research and the people who need it, accelerating the breakthroughs of new treatments. The platform simplifies the process of finding clinical trials by allowing patients to answer a few easy-to-understand questions about their condition and medical history. Antidote Match then presents relevant trials, cutting through the technical language often found on sites like ClinicalTrials.gov. The tool is available on Antidote’s website and is integrated into over 250 partner websites, including patient advocacy groups and health portals, reaching millions of patients monthly. For sponsors, Antidote Match offers precision recruitment services, screening patients on detailed eligibility criteria, including biomarkers and treatment history, to deliver high-quality patient referrals and accelerate enrollment timelines.

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Key Features

AI-powered patient-to-trial matching
Structured data and proprietary algorithms for eligibility exploration
Patient-friendly search interface
Integration with over 250 partner websites
Precision recruitment for sponsors
Deeper pre-screening based on detailed eligibility criteria (e.g., biomarkers, treatment history)
Multi-study screening for sponsors
Patient alerts for new matching trials
Customizable user tracking and demographics for partners
API available for integration

Use Cases

Accelerating clinical trial recruitment for pharmaceutical companies and CROs
Connecting patients with relevant clinical trials
Providing patient advocacy groups with a free clinical trial search tool for their communities
Optimizing patient engagement and retention in clinical trials
Gaining insights into patient populations through aggregated, anonymous demographic and medical data
Facilitating doctor-patient discussions about clinical trial participation

What Physicians Need to Know

Evidence Base

Antidote Match leverages data from ClinicalTrials.gov and direct sponsor partnerships. It uses structured eligibility criteria and proprietary algorithms to determine patient eligibility for trials. The platform also incorporates medical ontologies to translate complex trial information into an easy-to-understand format for patients.

Clinical Validation Studies

While the provided information doesn't detail specific clinical validation studies of Antidote Match as a diagnostic or treatment decision tool for physicians, its core function is to accurately match patients to clinical trials based on their health profiles and trial eligibility criteria.

Alert Fatigue Management

Antidote Match's primary function is patient-to-trial matching and providing notifications when new, relevant trials become available. It's not a general clinical decision support tool for diagnosis and treatment that generates numerous alerts for physicians, thus alert fatigue in that context is not a primary concern for this specific tool.

Differential Diagnosis Support

Antidote Match focuses on connecting patients with clinical trials based on their existing diagnoses and health profiles, rather than providing differential diagnosis support for physicians.

Guideline Update Frequency

Antidote Match continuously scans and updates its trial listings as new recruiting trials appear, drawing data daily from ClinicalTrials.gov and direct sponsor partnerships.

Clinical Workflow Integration

Antidote Match integrates with various partners, including patient advocacy groups and health portals, by embedding its search engine on their websites. It also integrates with clinical trial technology platforms like StudyTeam to streamline workflows for sites and deliver patient referrals and demographic information.

Physician Tip

Physicians can leverage Antidote Match as a valuable resource to help their patients find relevant clinical trials. By directing patients to Antidote Match, physicians can empower them to explore potential new treatment options and contribute to medical research. It's important to discuss any potential trial participation with patients to ensure it aligns with their current treatment plans and overall health goals. The tool can also provide insights into patient populations and their interest in specific trial criteria, which can be beneficial for understanding the research landscape.

Antidote Match has extensive integration capabilities, particularly with patient advocacy groups and health portals, allowing them to embed the search engine directly on their websites. It also integrates with clinical trial management platforms like StudyTeam to facilitate the referral and enrollment process, providing sites with higher quality referrals and sponsors with actionable enrollment data. Furthermore, Antidote is partnering with companies like SEQSTER to integrate comprehensive patient data, including medical history, genomic data, and lifestyle factors, for more accurate trial matching.

At a glance

Pricing Contact for pricing

Deployment Cloud Based (SaaS), API Integration, Embeddable Search Engine For Websites

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Details

Category	Clinical Decision Support & Reference, Drug Discovery & Research
Pricing	Contact for pricing Free for patients; SaaS offering for sponsors (Enterprise Match); Group Practice: $149/provider/month (for Antidote AI, a different product); Enterprise: Custom pricing (for Antidote AI, a different product)
Deployment	Cloud-based (SaaS), API integration, embeddable search engine for websites
Compliance
BAA Available	Yes AI-estimated
HIPAA Compliant	Yes AI-estimated
FDA Status	Unknown AI-estimated — unknown
Integrations
EHR	Not specified
Specialties	Family Medicine, Internal Medicine, Oncology

What the Web Says

Antidote Match is generally well-regarded as a solution for patient-trial matching, praised for its ability to connect patients with relevant clinical trials efficiently. Physicians appreciate its potential to improve patient access to research, while tech reviewers highlight its sophisticated algorithm and user-friendly interface. Some concerns exist regarding the completeness of trial listings and the potential for information overload.

Overall: Positive

Strengths

Efficient and accurate patient-trial matching
Improves patient access to clinical research
User-friendly interface for both patients and physicians
Sophisticated algorithm for precise matching
Reduces manual effort in trial recruitment
Supports a wide range of therapeutic areas

Limitations

Completeness of trial listings can vary
Potential for information overload for some users
Integration challenges with existing EHR systems for some practices
Reliance on patient-provided information for accuracy
Limited direct physician input on trial criteria in some workflows
Cost can be a barrier for smaller research sites

Based on reviews from: Antidote.com, G2, Capterra, Reddit (various subreddits related to healthcare IT and clinical trials), Healthcare IT News, Physician forums and blogs

Last updated: 2026-08-08

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Press & Coverage

Melanoma Research Alliance

Melanoma Research Alliance and Antidote Improve the Clinical Trial Navigator Experience for Patients and Caregivers

The Melanoma Research Alliance (MRA) and Antidote announced improvements to the Clinical Trial Navigator, powered by Antidote Match, to enhance the clinical trial search experience for melanoma patients and caregivers. These updates focus on user-centric design and functionality, particularly for rare melanoma subtypes and earlier disease stages.

2024-03

Antidote Technologies

Antidote and XpertPatient.com partner to empower those new to a cancer diagnosis to easily find clinical trials

Antidote Technologies partnered with XpertPatient.com to integrate Antidote Match, providing newly-diagnosed cancer patients with access to a patient-friendly clinical trial search. This collaboration aims to increase patient understanding of clinical trials and awareness of treatment options.

2023-02

Business Wire

Antidote Technologies Unveils Smart COVID-19 Clinical Trial Search to Speed Up Treatment and Vaccine Research Worldwide

Antidote Technologies added COVID-19 trials to its Antidote Match platform, allowing individuals to quickly find and be matched to clinical trials for COVID-19 treatment and prevention. The platform uses structured eligibility criteria and proprietary algorithms to connect patients with relevant studies globally.

2020-04

PatientPoint

PatientPoint and Antidote Team Up to Drive Clinical Trial Recruitment at the Point of Care

PatientPoint and Antidote Technologies announced a partnership to enhance clinical trial recruitment by directing patients and providers to Antidote Match at over 7,300 primary care and subspecialty practices. This initiative aims to bridge the gap between medical research and patients by facilitating discussions about clinical trials at the point of care.

2019-02

Emerj Artificial Intelligence Research

AI and Machine Learning for Clinical Trials - Examining 3 Current Applications

This article discusses Antidote Match as an application of AI and machine learning in clinical trials, highlighting its ability to connect patients to medical research studies. The platform uses algorithms trained on patient eligibility criteria to search thousands of open trials based on user responses.

2018-09

Global Genes

A Matchmaker for Patients Seeking Clinical Trials - Global Genes

Global Genes announced a partnership with Antidote Technologies to integrate the Antidote Match search engine into patient advocacy websites, allowing patients to easily explore eligibility for trials listed on ClinicalTrials.gov. This aims to simplify the process of finding clinical trials for patients, especially those with rare diseases.

2018-03

pharmaphorum

Merck funds Antidote's clinical trial matching tech

Antidote, formerly TrialReach, secured $11 million in funding led by Merck Global Health Innovation, to expand its Antidote Match platform. The funding will support the integration of electronic health record and genetic mutation matching, and global expansion, aiming to increase clinical trial participation.

2017-09

Multiple Sclerosis News Today

MS Clinical Trials and Patient Enrollment Goal of MSAA Partnership - Multiple Sclerosis News Today

The Multiple Sclerosis Association of America (MSAA) partnered with Antidote Technologies to make Antidote Match available on MSAA's website. This tool uses natural language processing and artificial intelligence to help individuals with MS find relevant clinical trials by answering a few questions.

2017-01

Videos

Product demos, reviews, and walkthroughs for Antidote Match.

Karan Aujla - Antidote (Lyrics)

Musicgenree

[PROJECT 7] Final Match uff1cAntidoteuff1e ud0acub9c1ud30cud2b8 ud22cud45c @uc720uc601uc11c(YOO YOUNGSEO)

uace0uace0uc53d GOGOSING

[PROJECT 7] u266a Antidote @Final Match | ucd5cuc885ud654

uace0uace0uc53d GOGOSING

Find Your Perfect Match - phaware + Antidote Clinical Trials Matching Tool

phaware global association

phawareu00ae + Antidote = Accelerated Lung Disease Research

phaware global association

uc720uc601uc11c - Antidote uba40ud2f0ucea0 uc9c1ucea0 [4K] @241227 PROJECT7 FINAL MATCH Antidote YOOYOUNGSEO FANCAM ud504ub85cuc81dud2b87 ud30cuc774ub110 uc548ud2f0ub3c4ud2b8

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View all on YouTube

Frequently Asked Questions

How does Antidote Match integrate into my existing clinical workflow and electronic health record (EHR) system?

Antidote Match is primarily a clinical trial matching service that connects patients with trials. While Antidote aims to simplify healthcare management and can integrate with Hospital Information Systems (HL7) for managing patient details and medical histories, specific EHR integration details for physicians using Antidote Match for clinical decision support would require direct inquiry with Antidote.

What are the compliance implications and data security measures associated with using Antidote Match for patient referrals to clinical trials?

Antidote emphasizes compliance with applicable laws and regulations, including anti-kickback laws, and has a dedicated compliance department. They also focus on HIPAA compliance for managing patient data. When patients use Antidote Match, their demographic and medical data is aggregated anonymously to provide insights into patient populations.

Are there alternative clinical decision support tools for trial matching that I should consider, and how does Antidote Match compare?

Yes, alternatives exist. While Antidote Match focuses on connecting patients with trials they may be eligible for right now, other tools like TrialsAlert offer ongoing research monitoring. Other clinical trial management systems and recruitment services include Viedoc, Clinical Research Suite, Florence eBinders, Elligo Health Research, and ClinicalConnection. Antidote Match differentiates itself with its precision matching based on detailed eligibility criteria, including treatment history and biomarkers, and multi-study screening capabilities.

What is the pricing model for physicians or healthcare systems to utilize Antidote Match for their patients?

Antidote Match is generally free for patients and patient advocacy group partners, as its revenue comes from pharmaceutical sponsors who pay for recruitment services. Antidote also offers a product called Match Enterprise for sponsors to create a matching experience for their studies, suggesting a business-to-business model for healthcare organizations.

What are the limitations of Antidote Match in terms of trial coverage, patient populations, or the complexity of eligibility criteria it can handle?

Antidote Match leverages medical ontologies and proprietary algorithms to match patients to trials based on complex inclusion and exclusion criteria, aiming to simplify the process for patients. While it strives for comprehensive coverage of US trials, the complexity of eligibility criteria, especially for phase 3 and oncology trials with narrow windows, remains a challenge in recruitment. The tool is designed to handle detailed eligibility, including treatment history and biomarkers.

How does Antidote Match ensure the quality and relevance of the clinical trials presented to patients?

Antidote Match uses structured data and proprietary algorithms to explore a patient's eligibility for every trial, going beyond basic diagnosis matching to include treatment history, comorbidities, and lab results. This precision matching helps identify patients who genuinely qualify, aiming to reduce screen failure rates. They also partner with organizations like SEQSTER to leverage a 360u00b0 view of patient data for more accurate matching.

Can Antidote Match help address the issue of diverse patient representation in clinical trials?

Yes, Antidote aims to foster diversity in drug development. Through partnerships and by providing access to patient medical records, their collaboration with SEQSTER, for instance, helps ensure better representation of underserved populations in clinical trials, addressing barriers such as lack of information and logistical challenges.

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