Cardiac CT Function Software Application

by Circle Cardiovascular Imaging  · Based in Canada → — AI-Powered Cardiac CT Function Analysis for Enhanced Diagnosis
Cardiology Cardiothoracic Surgery Radiology

Contact for pricing
Regulatory Status Disclosed

Overview

The Cardiac CT Function Software Application by Circle Cardiovascular Imaging is an advanced software tool designed to assist medical professionals in analyzing cardiac function from multi-phase, multi-slice cardiovascular CT angiography images. It leverages AI/ML algorithms to accurately segment cardiac structures, including the left and right ventricles, and compute key function metrics such as end diastolic volume (EDV), end systolic volume (ESV), stroke volume (SV), ejection fraction (EF), cardiac output (CO), cardiac index (CI), and LV myocardial mass.

This application is part of Circle’s broader cvi42 platform, which offers a comprehensive, vendor-neutral solution for cardiovascular imaging analysis across both CT and MR modalities. The software provides both manual and semi-automatic segmentation capabilities, along with 2D/3D visualization and multiplanar reconstruction of original CT data. It aims to improve patient throughput, accuracy, and reproducibility in cardiac imaging workflows, supporting faster, more reproducible, and efficient interpretation of studies.

The cvi42 platform, including the Cardiac CT Function module, integrates seamlessly with existing systems and workflows, offering full DICOM and PACS connectivity. It is utilized globally in over 1700 hospitals across more than 90 countries, demonstrating its widespread adoption and clinical validation.

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Key Features

  • AI/ML algorithms for cardiac structure segmentation
  • Quantification of cardiac function metrics (EDV, ESV, SV, EF, CO, CI, LV myocardial mass)
  • Manual and semi-automatic heart segmentation (LV, RV)
  • 2D/3D visualization and multiplanar reconstruction
  • Integrated reporting with infographics and screenshots
  • Vendor-neutral solution (supports various operating systems and scanner types)
  • Full DICOM and PACS connectivity
  • Coronary plaque analysis (total, calcified, non-calcified, low attenuation)
  • Calcium scoring and risk classification
  • Pre-procedural planning tools for structural heart interventions

Use Cases

  • Qualitative and quantitative evaluation of cardiovascular CT images
  • Assessment and evaluation of cardiac function
  • Coronary artery disease evaluation and risk stratification
  • Pre-procedural planning for transcatheter aortic/mitral valve replacement
  • Clinical diagnosis decision support in cardiovascular imaging
  • Cardiovascular imaging research

What Physicians Need to Know

Cardiac CT/MRI Analysis
The software is designed for qualitative and quantitative evaluation of multi-phase, multi-slice cardiovascular CT angiography images in DICOM Standard format. It assists in assessing and evaluating cardiac function by performing manual and semi-automatic heart segmentation of the left and right ventricles (LV and RV). Key metrics calculated include end diastolic volume, end systolic volume, stroke volume, ejection fraction, cardiac output, cardiac index, and LV myocardial mass. It also supports visualization, evaluation, and analysis of heart function through the calculation of volume and mass parameters. The cvi42 v6.1 release, which includes this application, features machine-learning AI enhancements for coronary analysis and aortic valve cusp point detection. It can also be used for cardiac MRI images to provide detailed measurements of heart muscle deformation and improve efficiency in post-processing and reporting through automated segmentation.
Coronary Artery Assessment
As part of the cvi42 v6.1 release, the software includes machine-learning AI enhancements and upgrades for coronary analysis, with tools to automatically characterize and quantify plaque within the coronary arteries.
AHA/ACC Guideline Alignment
The device is intended to be used as an aid to the existing standard of care and does not replace existing software applications that physicians use.
Physician Tip

This Cardiac CT Function Software Application is a valuable AI-powered aid for assessing cardiac function from CT angiography images. Leverage its semi-automatic segmentation and quantitative metrics (e.g., ejection fraction, volumes, mass) to enhance your diagnostic workflow. Remember that the software is a supportive tool; always apply your clinical judgment and verify AI-generated outputs before making clinical decisions. The machine-learning enhancements for coronary analysis can assist in plaque characterization and quantification.

The Cardiac CT Function Software Application is designed for the qualitative and quantitative evaluation of cardiovascular CT images in a DICOM Standard format. It is part of Circle Cardiovascular Imaging's broader cvi42 platform.

Details

Category Cardiology AI, Radiology & Imaging AI
Pricing Contact for pricing
  • Flexible subscription model; volume-aligned pricing; pay-per-process option available for certain modules like plaque analysis
DeploymentOn-premise software, integrated into hospital or private practice environments. Server pulls DICOM data from PACS.
Compliance
BAA AvailableUnknown AI-estimated
HIPAA CompliantUnknown AI-estimated
FDA Status 1 AI-estimated

The Cardiac CT Function Software Application received U.S. FDA 510(k) premarket approval (K241038) on June 7, 2024. It is cleared for qualitative and quantitative evaluation of cardiovascular CT images to calculate and display cardiac function metrics.

Integrations
EHR Not specified
Specialties Cardiology, Cardiothoracic Surgery, Radiology

What the Web Says

The Cardiac CT Function Software Application by Circle Cardiovascular Imaging (Circle CVI) is an FDA-cleared, AI-powered software designed for post-acquisition analysis of cardiac CT angiography images. It assists qualified medical professionals in assessing and evaluating cardiac function by segmenting cardiac structures and quantifying key metrics like ejection fraction, volumes, and coronary plaque analysis. The software is integrated into the broader cvi42 platform, which offers a comprehensive suite of tools for cardiac imaging.

Overall: Mixed

Strengths

  • Advanced AI-powered post-acquisition analysis of cardiac CT images.
  • Provides quantification of function metrics (ejection fraction, volumes) and detailed coronary plaque analysis.
  • Vendor-neutral solution, supporting various operating systems and scanner types.
  • Full DICOM and PACS connectivity for seamless integration into hospital IT environments.
  • On-premise deployment allows for in-house analysis, improving data control, processing times, and workflow efficiency.
  • Improved provider satisfaction, faster turnaround times, and reduced IT/administrative burden.

Limitations

  • Requires user interaction for segmentation and interpretation, despite AI assistance.
  • Innovation in AI application is primarily focused on post-processing rather than image acquisition automation.
  • Pricing information is not publicly disclosed.
  • The CT Function Module's functionality is dependent on the type of vendor acquisition equipment.
  • The device is intended as an aid and does not replace existing software applications physicians use.
  • Limited publicly available reviews from independent sources like G2, Capterra, or Reddit.

Last updated: 2026-07-17

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Videos

Product demos, reviews, and walkthroughs for Cardiac CT Function Software Application.

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Frequently Asked Questions

AI-powered cardiac CT function software significantly improves diagnostic accuracy by automating the quantification of coronary plaque, stenosis, and functional parameters like CT-FFR, often with high agreement to gold standards. It also boosts workflow efficiency by reducing analysis and reporting times, allowing clinicians to interpret cases faster while maintaining diagnostic accuracy.
Many AI cardiac CT solutions have received regulatory clearances such as FDA 510(k) and CE Mark, indicating their safety and effectiveness for clinical use. To ensure HIPAA compliance and patient data privacy, these systems typically employ end-to-end data encryption, robust access controls, de-identification techniques for training data, and require Business Associate Agreements (BAAs) with vendors.
AI-driven analysis often outperforms traditional manual methods in terms of speed, reproducibility, and consistency, especially in detecting obstructive stenosis and quantifying plaque. While traditional methods are labor-intensive and prone to interobserver variability, AI streamlines these processes, though human oversight remains crucial for comprehensive interpretation.
The cost of implementing AI in healthcare, including cardiac CT function software, can range from $50,000 to over $500,000, depending on complexity, customization, and integration needs. This includes expenses for software licensing, data preparation, regulatory validation (which can add $100,000-$500,000+), integration with existing PACS/RIS, and ongoing maintenance.
AI models can exhibit limitations such as algorithmic bias, particularly concerning diverse patient populations or atypical anatomies, often stemming from imbalanced training datasets. Challenges also include generalizability to varied scan protocols and vendors, interpretability of AI decisions, and the need for robust clinical validation in real-world settings. Addressing these requires diverse training data, ethical frameworks, and continuous monitoring.
Adopting AI cardiac CT software requires significant IT infrastructure, including robust computing power (often cloud-based or on-premises GPUs) and seamless integration with existing PACS/RIS and EHR systems. Challenges include data silos, lack of interoperability standards, and the technical complexity of building custom APIs or middleware to connect disparate systems, which can add substantial costs.

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Suggest an Edit → | Last Verified: 2026-04-18 | First Added: 2026-04-18
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