CLARUS (700)
Overview
The ZEISS CLARUS 700 is a comprehensive, AI-enhanced ultra-widefield (UWF) retinal imaging system designed for eye care specialists. It combines UWF imaging with true color, excellent clarity, and a complete suite of imaging modalities to provide detailed views of the retina from the macula to the far periphery.
Powered by Broad Line Technology, the CLARUS 700 captures images that closely resemble the natural coloration of the fundus as seen during clinical examination, utilizing red, green, and blue Light Emitting Diodes (LEDs).
Key imaging modalities include True Color (with RGB channel separation), Fluorescein Angiography (FA), Fundus Autofluorescence (FAF-Green and FAF-Blue), Infrared (IR) imaging, and external eye imaging. It also offers advanced features like PrecisionFocus for rapid focusing on areas of interest, AutoBright for optimizing angiogram brightness, and AI-powered GazePoint technology to facilitate montaging by identifying the optic nerve as a focal point, ensuring sharper and more detailed UWF images.
The system is designed to maximize workflow efficiency, provide a comfortable patient experience, and assist in the diagnosis and monitoring of various retinal diseases, including age-related macular degeneration, diabetic retinopathy, and retinal vascular occlusions.
Reviewed by Pouyan Golshani, MD — Interventional Radiologist
Key Features
- Ultra-widefield (UWF) imaging (up to 200u00b0 with montaging, 133u00b0 single capture)
- True Color imaging with Red, Green, and Blue LED illumination
- Fluorescein Angiography (FA)
- Fundus Autofluorescence (FAF-Green, FAF-Blue)
- Infrared (IR) imaging
- External Eye imaging
- AI-powered GazePoint technology for accurate gaze derivation and montaging
- PrecisionFocus technology for enhanced region-of-interest examination
- AutoBright software for optimized angiogram brightness
- High resolution (up to 7.3 u00b5m detail)
- Comprehensive suite of imaging modalities
Use Cases
- Diagnosis and monitoring of retinal diseases (e.g., AMD, diabetic retinopathy, retinal vascular occlusions)
- Visualization of vascular structures of the retina and choroid
- Assessment of the peripheral retina for early disease detection
- Documentation of ocular disease indications in various regions of the eye
- Evaluation of macular pigment and pigment epithelium health
- Comprehensive fundus examinations and treatment planning
What Physicians Need to Know
Leverage the CLARUS 700's true color and multi-modal imaging (FA, FAF, IR) to gain a comprehensive view of retinal pathologies from the macula to the far periphery. Utilize the AI-enhanced capture features like PrecisionFocus, AutoBright, and GazePoint to optimize image quality and streamline workflow, especially for challenging cases or patients with poor fixation. Integrate CLARUS images with OCT data via the ZEISS Integrated Diagnostic Imaging platform for a holistic patient assessment, particularly for conditions like AMD and glaucoma. The high sensitivity for DR detection makes it a robust tool for diabetic eye screening programs.
The ZEISS CLARUS 700 is designed for seamless integration within the ZEISS Retina Workflow and the broader Integrated Diagnostic Imaging platform. It combines exam data from devices like the CLARUS and CIRRUSu2122 HD-OCT to provide a unified view for more efficient and insightful treatment decisions. It also integrates with ZEISS Glaucoma Workplace software. This connectivity supports an end-to-end 'screening-to-treatment' solution.
Details
| Category | Ophthalmology AI |
| Pricing | Contact vendor — Pricing information is not publicly disclosed. Contact Carl Zeiss Meditec sales for a quote. |
| Deployment | On-premise (device-based) |
| Compliance | |
| BAA Available | Yes AI-estimated |
| HIPAA Compliant | Yes AI-estimated |
| FDA Status |
Yes AI-estimated The CLARUS 700 received initial FDA 510(k) clearance in July 2019. It subsequently received an updated 510(k) clearance (K243878, dated April 17, 2025) for new functionality, specifically Indocyanine Green Angiography (ICGA), as an active, software-controlled, high-resolution ophthalmic imaging device for in-vivo imaging of the human eye. |
| Integrations | |
| EHR | Not specified |
| Specialties | Ophthalmology |
What the Web Says
The ZEISS CLARUS 700 is an ultra-widefield (UWF) retinal camera that offers true color imaging and a comprehensive suite of modalities, including fluorescein angiography (FA) and indocyanine green angiography (ICGA) functionality. It is designed to provide high-resolution images of the retina, from the macula to the far periphery, aiding in the diagnosis and monitoring of various retinal diseases. Physicians generally praise its image quality, true color representation, and ease of use, particularly in a non-mydriatic setting.
Overall: PositiveStrengths
- True color imaging provides natural-looking fundus photographs, similar to direct observation.
- High resolution and clarity across a wide field of view (up to 200u00b0 with montaging, 133u00b0 single capture).
- Multiple imaging modalities available on a single platform (true color, FAF blue/green, FA, external photography, infrared imaging, ICGA).
- Features like PrecisionFocus, AutoBright, and GazePoint (AI-based) enhance image quality, optimize brightness, and facilitate montaging, improving workflow efficiency.
- Can detect more referable retinopathy and peripheral lesions compared to conventional imaging.
- Generally well-tolerated by patients, including children, and often reduces the need for pupil dilation.
Limitations
- Some users have reported issues with the CLARUS 500 model, including software glitches and hardware problems, raising concerns about the 700.
- One Reddit user was not impressed with a demo, citing struggles to get clear photos and low image quality.
- The device gives off a bright flash that some patients may not like.
- Montaging multiple images to achieve ultra-widefield views can be difficult, especially with uncooperative patients like babies.
- The Optos camera may capture a larger retinal area in a single image and has a wider field of view in some comparisons.
- The cost of the machine can be a significant barrier.
Based on reviews from: RetinaToday, Review of Optometry, Ophthalmic Photographers' Society, Insight, Eyetube, YouTube, Reddit, ResearchGate, Stock Titan, Optometry Times, Review of Ophthalmology, Retinal Physician, PMC, Medilex, amedeo lucente, Revista Mu00e9dica de la Universidad Autu00f3noma de Sinaloa, SciELO Mu00e9xico
Last updated: 2026-07-17
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Dr Agrawal recommends ZEISS CLARUS 700: Better diagnostics, tailored treatments, improved care
