Deep 6 AI
Overview
Deep 6 AI is an innovative healthcare technology company that leverages artificial intelligence (AI) to accelerate and improve clinical trial recruitment. It disrupts the clinical trial enrollment process by transforming the way researchers identify eligible patients. Using AI and natural language processing (NLP), the platform analyzes both structured and unstructured real-time clinical data from Electronic Medical Records (EMRs), including physician notes, pathology reports, genomics results, and lab reports, to precisely match eligible patients to clinical trials in minutes, not months.
The Deep 6 Precision Research Ecosystem connects healthcare organizations (HCOs), researchers, treating physicians, sponsors, and Contract Research Organizations (CROs), facilitating collaboration and advancing research. The platform is deployed enterprise-wide at health systems and is built on a secure, HIPAA-compliant cloud environment (AWS Virtual Private Cloud, Amazon EKS cluster) to ensure data security and privacy, with data ownership remaining with the healthcare organization.
Deep 6 AI was acquired by Tempus AI on March 11, 2025, expanding Tempus’s platform reach and reinforcing their shared mission of accelerating precision medicine.
Reviewed by Pouyan Golshani, MD — Interventional Radiologist
Key Features
- AI-Powered Patient Matching
- Natural Language Processing (NLP) on Unstructured Data
- Real-Time EMR Data Querying
- Clinical Trial Cohort Builder
- Site Feasibility Assessment
- Real-World Evidence (RWE) Generation
- Trial Recommender for Physicians
- Genomics Integration Module
- EHR Integration (Epic, Cerner)
- De-identification and security controls
Use Cases
- Accelerate patient recruitment for clinical trials
- De-risk trial planning and site selection
- Generate Real-World Evidence (RWE)
- Identify patients for precision medicine trials
- Reduce clinical trial delays
- Improve patient outcomes and satisfaction
What Physicians Need to Know
Physicians can utilize Deep 6 AI to rapidly identify cutting-edge treatment options for their patients by efficiently matching them to relevant clinical trials. The platform significantly reduces the manual burden of patient screening and offers a holistic view of patient data, including critical genomic information, ensuring highly precise and personalized trial matching. This enables faster access to advanced therapies and supports informed decision-making.
Deep 6 AI integrates directly with major Electronic Medical Record (EMR) systems such as Epic and Cerner, leveraging secure, normalized data pipelines. The platform is built on a secure cloud environment (AWS Virtual Private Cloud) and utilizes the Spark NLP platform for advanced text analysis. It also employs FHIR for robust data interoperability. Deep 6 AI was acquired by Tempus AI in March 2025, indicating deeper future integrations within Tempus's broader precision medicine and AI platform. Additionally, it partners with organizations like Graticule for specialized real-world data services.
Details
| Category | Drug Discovery & Research |
| Pricing |
Enterprise licensing model; not publicly disclosed.
|
| Deployment | Cloud-based (AWS Virtual Private Cloud, Amazon EKS cluster), deployed enterprise-wide at health systems. |
| Compliance | |
| BAA Available | Unknown AI-estimated |
| HIPAA Compliant | Unknown AI-estimated |
| FDA Status |
Unknown AI-estimated Publications and case reports show that Deep 6 AI substantially accelerates and improves recruitment efficiency at health systems and research networks, but there is no evidence that the platform has been evaluated as a clinical diagnostic/therapeutic device or undergone formal clinical validation trials in that sense; validation is operational (recruitment metrics), not clinical outcome–based. |
| Integrations | |
| EHR | Not specified |
| Specialties | Cardiology, Neurology, Oncology |
What the Web Says
Deep 6 AI is a clinical trial acceleration software that uses artificial intelligence (AI) and natural language processing (NLP) to identify eligible patients for clinical trials. It analyzes both structured and unstructured patient data from electronic health records (EHRs), including physician notes, pathology reports, and 'omics data, to match patients to complex trial protocols in minutes rather than months. The platform aims to address the inefficiencies of traditional patient recruitment methods, which often lead to trial delays and increased costs.
Overall: PositiveStrengths
- Accelerates patient recruitment from months to minutes.
- Analyzes both structured and unstructured clinical data, including physician notes and pathology reports.
- Improves precision matching of patients to complex trial criteria, reducing false positives.
- Helps find hard-to-reach or rare disease patients.
- Provides a self-service platform for researchers to build cohorts and refine study criteria.
- Operates in a secure, HIPAA-compliant environment, protecting patient privacy.
Limitations
- Predictive performance depends on the quality, completeness, and timeliness of source data.
- Outputs are for decision support only and require validation by clinical and trial teams.
- Integration with proprietary EHRs and other systems may require significant IT effort.
- Regulatory, privacy, and compliance review is necessary when using AI outputs.
- Potential for bias and representativeness issues if models are trained on under-captured populations or coding disparities.
- Model drift and data-schema changes can affect performance.
Based on reviews from: The Silicon Review, SourceForge, pharmaphorum, Deep 6 AI: How Top Life Sciences Teams Are Slashing Trial Timelines by Months, Deep 6 and Carle Partner to Deploy Artificial Intelligence in Clinical Trials, Indeed.com, Growjo, Startup Deep 6 Lands $17 Million To Use AI To Help Find Patients For Clinical Trials, Reddit (r/ClinicalResearchAI), New Jersey Alliance for Clinical and Translational Science (NJ ACTS), Advancing Clinical Research With The Use Of Deep 6 AI, YouTube (Deep 6 AI Leverages AWS to Accelerate Clinical Trial Recruitment and Digitize Clinical Workflows), Work in progress Integrating AI-Enabled Clinical Trial Matching into Operations
Last updated: 2026-08-21
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Press & Coverage
Videos
Product demos, reviews, and walkthroughs for Deep 6 AI.
Deep 6 AI Leverages AWS to Accelerate Clinical Trial Recruitment and Digitize Clinical Workflows
AWS Events
Deep 6 AI + Cedars Sinai Medical Center
Deep 6 AI
What does Deep6 AI do? Ask Founder and CEO Wout Brusselaers!
The INNOVATORS
Using AI to find experimental treatments for patients
KCBD NewsChannel 11 - Lubbock, TX
Episode 1 AI in Clinical Research w/Rajesh Sharma of Deep 6 AI
The Research Slayer Podcast
Deep 6 AI: A Category Creator
Deep 6 AI
