GIQuant

by Motilent  · Based in United Kingdom →Quantifying gut motility from MRI
Gastroenterology Radiology

Contact for pricing
Regulatory Status Disclosed

Overview

GIQuant by Motilent is a post-processing medical image analysis software designed to measure and monitor gastrointestinal function. The tool is primarily utilized by gastroenterologists and abdominal radiologists in both pediatric and adult care settings to assist in the assessment of small bowel Crohn’s disease.

The software integrates into existing clinical workflows by processing standard dynamic (cine) magnetic resonance enterography (MRE) sequences. It operates within a DICOM-compliant environment, allowing clinicians to analyze imaging data without disrupting established PACS or imaging protocols. Notable capabilities of GIQuant include:

  • Objective Motility Mapping: Uses image registration and optical flow algorithms to convert subjective cine MRI sequences into a quantitative, unitless motility score.
  • Parametric Visualization: Generates parametric heatmaps of the bowel wall to help identify areas of reduced peristalsis, which are often associated with active inflammation or disease progression.
  • Therapeutic Monitoring: Enables objective tracking of small bowel motility changes over time, helping clinicians assess therapeutic response and support treatment decisions.

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Key Features

  • Quantifies intestinal motility from MRI scans
  • Provides objective, quantitative motility scores
  • Aids in diagnosis, monitoring, and treatment response assessment
  • Non-invasive assessment of gut function
  • Integrates into existing DICOM-compliant clinical workflows
  • Supports personalized medicine approaches
  • Works with standard cine MRI sequences
  • Applicable retrospectively to historical MRI datasets
  • Outputs parametric maps and structured reports
  • CE marked (Class IIa) in addition to FDA cleared

Use Cases

  • Diagnosis of digestive diseases, especially Crohn's disease
  • Monitoring disease progression and activity over time
  • Assessing treatment response and efficacy of therapies
  • Personalized treatment planning for patients
  • Clinical research and drug development studies
  • Retrospective analysis and audit of patient data

What Physicians Need to Know

IBD Assessment Tools
GIQuant is a software solution that quantifies small bowel motility from cine MRI sequences, providing an objective score for assessing Crohn's disease activity in both adults and children. It helps track treatment decisions and monitor response to therapies, with research suggesting motility changes can appear before visible structural changes on MRI.
Procedure Documentation
GIQuant provides clinicians with a rapid, objective score for small bowel motility, reducing variability from subjective image interpretation and supporting standardization of reads. The software outputs a quantitative GIQuant score for defined bowel segments, which can be incorporated into MR enterography reporting.
Quality Metrics Tracking
By offering an objective, quantitative motility score, GIQuant helps standardize assessment of Crohn's disease activity across hospitals and clinical trials, contributing to improved clinical quality and patient safety.
Imaging System Compatibility
GIQuant is DICOM compatible and works directly with standard cine MRI sequences, requiring no special acquisition protocol beyond routine MR enterography. It can be installed within hospital infrastructure.
Physician Tip

Physicians should integrate GIQuant's objective small bowel motility scores with other clinical data, endoscopy findings, and biomarkers for a comprehensive assessment of Crohn's disease activity and treatment response. The tool is particularly useful for monitoring therapeutic efficacy, potentially identifying non-responders earlier, and standardizing MRI interpretations across different practitioners and institutions. It can also provide valuable insights in clinical research and drug development for IBD.

GIQuant is DICOM compatible, allowing it to integrate into standard radiology workflows and be viewed in 'off the shelf' DICOM viewers. It can be deployed within hospital infrastructure or accessed via Motilent's cloud-based platform, Entrolytics, for research and data management. Motilent has also partnered with Nuance AI solutions for deployment across healthcare providers in the U.S.

Details

Category Gastroenterology AI, Radiology & Imaging AI
Pricing Contact for pricing
  • GIQuant operates on a subscription model; contact Motilent directly for specific pricing information
DeploymentOn-premise, cloud-hybrid
Compliance
BAA AvailableUnknown AI-estimated
HIPAA CompliantUnknown AI-estimated
FDA Status 1 AI-estimated

GIQuant is FDA-cleared (Class II, 510(k)) AI medical image analysis software for assessing digestive diseases, particularly Crohn's disease, by quantifying intestinal motility from MRI scans. It is cleared for use in adults and children.

Integrations
EHR Not specified
Specialties Gastroenterology, Radiology

What the Web Says

GIQuant is an AI-powered software solution developed by Motilent that quantifies small bowel motility from cine MRI sequences, primarily for assessing Crohn's disease activity in both adults and children. It provides an objective motility score that can be tracked over time to monitor treatment response and disease progression, offering an additional layer of data to subjective MRI reports. The software is FDA cleared (Class II) and CE marked (Class IIa).

Overall: Positive

Strengths

  • Provides objective and quantitative assessment of small bowel motility, reducing variability from subjective image interpretation.
  • Helps monitor treatment response and disease progression in Crohn's disease, with motility changes potentially appearing before visible structural changes.
  • Can be easily applied to standard MRE protocols and is DICOM compatible, integrating into existing hospital infrastructure.
  • Aids in communicating treatment response in multidisciplinary team (MDT) meetings and provides a digestible format for patients to understand their disease control.
  • Supported by multiple peer-reviewed studies and has shown to help less experienced radiologists become more consistent.
  • Can be used in clinical research and drug development to support consistent assessment of Crohn's disease activity across sites.

Limitations

  • The source code for the software is not open, as it is only available for commercial use.
  • While GIQuant scores can change clinical impressions, there were no reported changes in actual treatment plans before and after reviewing the scores in one study.
  • The learning curve for the software can be high, especially for space managers (though this con was mentioned in a review for a different product named 'Quant' on Capterra, not specifically GIQuant).
  • Some general concerns about the accuracy and utility of gut microbiome tests were found on Reddit, though these were not specific to GIQuant which focuses on motility from MRI.

Based on reviews from: Motilent (motilent.com), Health AI Register, AuntMinnie, DigitalHealth.London, Oxford Academic, PMC, Reddit

Last updated: 2026-07-21

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Press & Coverage

PR Newswire
AI Gut-imaging Software Takes on the U.S. with FDA Clearance and National Hospital Partnership
Motilent announced FDA 510(k) clearance for GIQuant in the U.S., partnering with Nuance AI solutions to deploy the AI medical image analysis software for digestive diseases. GIQuant measures intestinal motility from MRI scans to aid in Crohn's disease treatment decisions.
2021-11
AuntMinnie
Motilent gets FDA clearance for AI gut imaging software
Motilent received U.S. FDA 510(k) clearance for GIQuant, an MR image analysis application for evaluating gastrointestinal function, initially focusing on Crohn's disease. The software measures intestinal motility and treatment response on standard MRI exams.
2021-12
DigitalHealth.London
Accelerator alumnus company Motilent receives FDA 510k clearance and national hospital partnership for gut-imaging software
Motilent's GIQuant, a clinically validated tool for Crohn's disease activity scoring based on intestinal motility, received FDA 510k clearance in the USA and will roll out in partnership with Nuance AI solutions. The software is already in use in UK institutions like Great Ormond Street Hospital.
2021-11
Tech Funding News
Motilent raises u00a31.2M to rollout its CE-marked GIQuant software
UK-based Motilent secured u00a31.2 million in NIHR funding to develop and deploy its GIQuant gut-imaging technology to over 10 NHS hospitals, focusing on Inflammatory Bowel Disease and Crohn's Disease. The investment builds on previous awards that accelerated GIQuant's development.
2022-05
Digital Health
Motilent secures additional funding for bowel care technology
Motilent received additional funding from the National Institute for Health and Care Research (NIHR) to further develop and roll out GIQuant, its AI medical image analysis technology for inflammatory bowel disease and Crohn's disease, to NHS hospitals.
2022-05
Journal of Crohn's and Colitis (Oxford Academic)
The CONTEXT trial: Real world clinical use of GIQuantu2014a motility MRI based activity biomarker for small bowel Crohn's disease
This study assessed the impact of implementing GIQuant, a motility MRI-based biomarker, on clinical impressions of treatment response in small bowel Crohn's disease. The results showed that GIQuant influenced gastroenterologists' assessment of patient status in nearly half of the cases.
2026-06
PMC (via Tokyo Medical and Dental University)
Motility Mapping Quantification Using the Classical Optical Flow Algorithm for Small Bowel Crohn's Disease: Comparison with Balloon-assisted Enteroscopy Findings
This study compares a new motility mapping software with GIQuant for small bowel Crohn's disease, using balloon-assisted enteroscopy as a reference standard. It highlights GIQuant as a well-validated commercial software for motility mapping.
2023-05
Motilent
Motilent Monthly Digest #15
This digest mentions that early data from the 5-year CONTEXT Trial showed GIQuant influenced nearly 50% of gastroenterologists' impressions of treatment response and shortened scan times. It also notes the increasing use of Entrolytics, Motilent's platform, for GI research.
2025-04

Videos

Product demos, reviews, and walkthroughs for GIQuant.

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Frequently Asked Questions

GIQuant integrates seamlessly into existing PACS and DICOM-compliant workflows, processing cine MRI sequences to provide objective motility scores. It is primarily used for adults and children with Crohn's disease to monitor disease activity and treatment response, helping physicians make more informed clinical decisions.
GIQuant is CE Marked (Class IIa) and FDA Cleared (Class II) for use in adults and children. For data privacy, it is GDPR compliant as all patient data is processed on-premises at the hospital, without cloud storage or external data transfer.
While GIQuant provides objective motility scores, it should not be used in isolation for clinical decision-making. Its results, such as motility scores, should be interpreted alongside established clinical findings, other imaging parameters, and biomarkers for a comprehensive assessment.
While other AI solutions exist for various GI applications like polyp detection in colonoscopy (e.g., GI Genius) or general radiology AI, GIQuant specifically focuses on quantifying small bowel motility from cine MRI. Its unique approach provides an objective score for intestinal movement, which can precede visible structural changes.
GIQuant operates on a subscription-based pricing model. Specific cost factors are not publicly detailed but typically depend on institutional size, anticipated usage, and the level of integration required within the existing IT infrastructure.
GIQuant enhances diagnostic assessment by providing objective, quantitative motility scores from cine MRI, reducing subjective interpretation variability. This data aids in monitoring treatment response, identifying non-responders earlier, and guiding therapeutic decisions in conditions like Crohn's disease.
While specific training details are not extensively covered in public search results, GIQuant is designed for seamless integration into existing PACS infrastructure. Motilent, the company behind GIQuant, would typically provide necessary support for installation, configuration, and user guidance to ensure effective clinical adoption.

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Suggest an Edit → | Last Verified: 2026-04-21 | First Added: 2026-04-21
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